{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-09-09",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "b59ff25b-0516-45ba-9c76-ba91a76c207f",
          "code": "P45974",
          "type": "PRIMARY",
          "url": "http://www.uniprot.org/uniprot/P45974",
          "code_system": "UNIPROT",
          "references": [
            "9bcc37dd-b362-4d5a-8f99-8ccdcf7897b8"
          ]
        },
        {
          "uuid": "86b62e48-d41b-4341-ab56-6f06380ed033",
          "code": "P45974",
          "type": "PRIMARY",
          "url": "https://pharos.nih.gov/idg/search?q=P45974",
          "code_system": "PHAROS",
          "references": [
            "9bcc37dd-b362-4d5a-8f99-8ccdcf7897b8"
          ]
        },
        {
          "uuid": "bdb7b415-6501-447e-9147-f3f6580a84e4",
          "code": "USP5",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/USP5",
          "code_system": "WIKIPEDIA",
          "references": [
            "9bcc37dd-b362-4d5a-8f99-8ccdcf7897b8"
          ]
        },
        {
          "uuid": "7641286a-88dd-40be-b7f4-e80c3725aac3",
          "code": "ZHG6J7FHG4",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        }
      ],
      "substance_class": "protein",
      "names": [
        {
          "uuid": "4da791c2-a732-49a0-9ca1-bcf3ccb8708c",
          "name": "DEUBIQUITINATING ENZYME 5",
          "stdName": "DEUBIQUITINATING ENZYME 5",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": false
        },
        {
          "uuid": "f5debb44-27c7-465f-b6c4-7037683d227f",
          "name": "ISOPEPTIDASE T",
          "stdName": "ISOPEPTIDASE T",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": false
        },
        {
          "uuid": "a29152ae-d149-4c9e-84e3-02bfb675290b",
          "name": "ISOT",
          "stdName": "ISOT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": false
        },
        {
          "uuid": "81c99f46-0eb2-4e17-a106-7e5fa0f5e83c",
          "name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5",
          "stdName": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": true
        },
        {
          "uuid": "f592caee-bd0d-4bf6-8c26-dc962a42cd47",
          "name": "UBIQUITIN THIOESTERASE 5",
          "stdName": "UBIQUITIN THIOESTERASE 5",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": false
        },
        {
          "uuid": "33384a85-d97e-49f0-900d-3af7c3c94a70",
          "name": "UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 5",
          "stdName": "UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 5",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "385802c8-1be5-4a47-9399-14fa169a92bd",
            "d8457f28-b4c2-4e96-bffd-0c4f045cde66"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "385802c8-1be5-4a47-9399-14fa169a92bd",
          "citation": "http://www.uniprot.org/uniprot/P45974",
          "url": "http://www.uniprot.org/uniprot/P45974",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "d8457f28-b4c2-4e96-bffd-0c4f045cde66",
          "citation": "UNIPROT",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9bcc37dd-b362-4d5a-8f99-8ccdcf7897b8",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493393834000,
          "tags": [
            "NOMEN"
          ]
        }
      ],
      "definition_type": "PRIMARY",
      "protein": {
        "uuid": "abf3c473-4c6e-4103-b113-9c9fe47133fe",
        "glycosylation": {
          "uuid": "35e68e2f-10bc-467f-b788-2d9812eff3c7"
        },
        "subunits": [
          {
            "uuid": "8f0b166f-1fdd-4a09-8484-342b0e732002",
            "sequence": "AELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYIYFYQRVAS",
            "subunit_index": 1
          }
        ],
        "references": [
          "385802c8-1be5-4a47-9399-14fa169a92bd"
        ],
        "disulfide_links": [
          {
            "sites": [
              {
                "residue_index": 194,
                "subunit_index": 1
              },
              {
                "residue_index": 815,
                "subunit_index": 1
              }
            ]
          }
        ],
        "other_links": [
          {
            "uuid": "7fe6e9ad-001e-4c49-af56-14a36f2850b5",
            "sites": [
              {
                "residue_index": 198,
                "subunit_index": 1
              },
              {
                "residue_index": 201,
                "subunit_index": 1
              },
              {
                "residue_index": 218,
                "subunit_index": 1
              },
              {
                "residue_index": 231,
                "subunit_index": 1
              }
            ],
            "linkage_type": "COORDINATION COMPOUND"
          }
        ],
        "protein_sub_type": "",
        "sequence_type": "COMPLETE"
      },
      "definition_level": "COMPLETE",
      "uuid": "f6fbf365-e10b-41b9-a1a2-12764d2c023f",
      "version": "4",
      "properties": [
        {
          "uuid": "e74fc317-4b4f-4e2c-b073-cbcbdd9832c6",
          "name": "MOL_WEIGHT",
          "type": "amount",
          "value": {
            "uuid": "e2c0893d-c149-4ab6-8957-9be77cf6ad22",
            "units": "DA"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        },
        {
          "uuid": "a27ddd25-5617-4d9b-adfc-9a9e407aed48",
          "name": "Molecular Formula",
          "value": {
            "uuid": "b0c95de8-d652-4812-a373-59eec2a6e584",
            "type": "ESTIMATED",
            "non_numeric_value": "C4237H6573N1135O1323P3S39"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "bf27e86d-afba-47fc-978f-7d5f8c89e8f0",
        "structural_modifications": [
          {
            "uuid": "74bb02c3-9129-4dc5-90c7-c6909c976401",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 155,
                "subunit_index": 1
              },
              {
                "residue_index": 778,
                "subunit_index": 1
              },
              {
                "residue_index": 782,
                "subunit_index": 1
              }
            ],
            "molecular_fragment": {
              "uuid": "ada4e1f7-8b7a-4558-b5e9-c1b5829c7b3e",
              "refuuid": "b6eb2edb-1b4d-46ad-92ad-a43f0f545926",
              "name": "DEXFOSFOSERINE",
              "unii": "VI4F0K069V",
              "linking_id": "VI4F0K069V",
              "ref_pname": "DEXFOSFOSERINE",
              "substance_class": "reference"
            },
            "structural_modification_type": "AMINO ACID SUBSTITUTION"
          },
          {
            "uuid": "7ed5f472-5db2-48b8-8da9-32dc02cd0383",
            "sites": [
              {
                "residue_index": 198,
                "subunit_index": 1
              },
              {
                "residue_index": 201,
                "subunit_index": 1
              },
              {
                "residue_index": 218,
                "subunit_index": 1
              },
              {
                "residue_index": 231,
                "subunit_index": 1
              }
            ],
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "44097a72-8b4b-48d0-a84a-d562636a44a3",
              "refuuid": "b5efe83d-a459-4030-b254-1047b15ee50a",
              "name": "C3H1-TYPE ZINC FINGER",
              "unii": "JKX41V9FYM",
              "linking_id": "JKX41V9FYM",
              "ref_pname": "C3H1-TYPE ZINC FINGER",
              "substance_class": "reference"
            },
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          }
        ]
      },
      "unii": "ZHG6J7FHG4"
    }
  ]
}