{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "a2df6f20-2182-48a0-b506-8d83f9321cd3",
          "code": "529-05-5",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=529-05-5",
          "code_system": "CAS",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e",
            "2f3faeae-1f4c-4ce0-a4cf-ee86d4047550"
          ]
        },
        {
          "uuid": "515777b1-3e73-4f74-8eeb-4902d011b894",
          "code": "C013872",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67013872",
          "code_system": "MESH",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "ef3621df-b3ad-448f-821f-37d747332d6a",
          "code": "CHAMAZULENE",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Chamazulene",
          "code_system": "WIKIPEDIA",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "7e17fc4a-16c5-4f45-a60f-dd0e4c343803",
          "code": "208-449-6",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.007.682",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "c003d850-2157-4277-8666-28970206b5b4",
          "code": "m3309",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m3309?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "5d0a8fd2-cfd1-4e65-b05f-f2eecd63e9f0",
          "code": "SUB71061",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "1624f55a-fc18-4edb-bd12-33a2325fad45",
          "code": "10719",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/10719",
          "code_system": "PUBCHEM",
          "references": [
            "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e"
          ]
        },
        {
          "uuid": "ecf72630-c26a-13a0-19dd-ea21ce86d987",
          "code": "DTXSID70200939",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID70200939",
          "code_system": "EPA CompTox",
          "references": [
            "7bb6fced-1147-0c79-a025-a577dd64d659"
          ]
        },
        {
          "uuid": "029c8fdc-bb54-401f-84a8-2569e1fec378",
          "code": "Z439UH6E5F",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "915d6843-04f8-4a8b-bce6-0fc63b73e18a",
          "code": "100000135558",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "9092fea5-e55f-1fee-d578-b0284957a6d4"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "80ba09c1-df5a-472a-b12f-ed937a6eb4fa",
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "96866edf-4065-44f6-9a78-30255345ccaf",
            "refuuid": "d22589be-437b-4af0-964f-d8fd6958cb3f",
            "name": "CHAMAZULENE",
            "unii": "Z439UH6E5F",
            "linking_id": "Z439UH6E5F",
            "ref_pname": "CHAMAZULENE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "fd058b85-3ba8-4287-b0c5-4f17946307f2",
          "type": "PARENT->CONSTITUENT ALWAYS PRESENT",
          "references": [
            "192c84ef-428d-457b-9654-815ef9410ee3"
          ],
          "related_substance": {
            "uuid": "f14a6877-e0d2-425e-af6c-6d6d792ffcd3",
            "refuuid": "2ba21cff-62f7-40a2-aa50-daef1722fcad",
            "name": "CHAMAEMELUM NOBILE FLOWER",
            "unii": "O2T154T6OG",
            "linking_id": "O2T154T6OG",
            "ref_pname": "CHAMAEMELUM NOBILE FLOWER",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "8bdec075-6fd2-40a7-b156-a28a55fdc5f9",
          "amount": {
            "uuid": "ced5a2a5-e41e-4b32-b5b5-09de3b1c81d8"
          },
          "type": "PARENT->CONSTITUENT ALWAYS PRESENT",
          "related_substance": {
            "uuid": "7b23fa0e-6fbb-40ca-abc0-8477ea242696",
            "refuuid": "3347cc3f-fac6-4a3c-945d-f0bd68dd3c46",
            "name": "CHAMOMILE",
            "unii": "FGL3685T2X",
            "linking_id": "FGL3685T2X",
            "ref_pname": "CHAMOMILE",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "0b7eedfb-f84e-46ec-acbc-43d49b7d4797",
          "name": "1,4-DIMETHYL-7-ETHYLAZULENE",
          "stdName": "1,4-DIMETHYL-7-ETHYLAZULENE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "d88b2b7e-287d-439c-9be6-ab23f4c0bd1a",
          "name": "7-ETHYL-1,4-DIMETHYLAZULENE",
          "stdName": "7-ETHYL-1,4-DIMETHYLAZULENE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8bde71d9-f621-47da-b757-d1784702509a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "59915a6e-97fb-4fea-8183-7784d43d9fb6",
          "name": "AZULENE, 7-ETHYL-1,4-DIMETHYL-",
          "stdName": "AZULENE, 7-ETHYL-1,4-DIMETHYL-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "6de32494-ad5b-45e2-b93e-fab778f5f6e3",
          "name": "BA-2784",
          "stdName": "BA-2784",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "9187c4fe-1a82-416a-bb57-6bb446455dba",
          "name": "CAMAZULENE",
          "stdName": "CAMAZULENE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "f82d2f63-dc04-439a-8cdf-c801e8cf0d8d",
          "name": "CHAMAZULEN",
          "stdName": "CHAMAZULEN",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "d1a15828-664f-4ee5-ad6e-7c770517e60d",
          "name": "CHAMAZULENE",
          "stdName": "CHAMAZULENE",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e8c73deb-2c13-4401-8db4-b4294299ad2d",
            "1cd75e77-6106-4489-89c1-ee134a5627e3",
            "ac84b05f-24a4-4a36-962c-f0b087ee5e34",
            "b62e6a9f-1258-41f6-8d1d-ca6f2bdb12d0",
            "8bde71d9-f621-47da-b757-d1784702509a",
            "b3dae390-5461-4266-93d8-4c873a7e5786",
            "c17fbc29-e855-4f8f-b5c5-1c1746967041",
            "7c5e6392-1be5-4c8d-899c-eb8875922c0a"
          ],
          "display_name": true,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "067fe956-918f-459c-9ad5-e08462323402",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "39c4bd87-4c88-4e26-8140-59e4f0d52a0b",
          "name": "CHAMAZULENE (CONSTITUENT OF CHAMOMILE) [DSC]",
          "stdName": "CHAMAZULENE (CONSTITUENT OF CHAMOMILE) [DSC]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a5746776-3171-4028-b379-ce59b94c052c",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "99153d2b-4e5e-42e4-8b8d-c97507b87811",
          "name": "CHAMAZULENE [MI]",
          "stdName": "CHAMAZULENE [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "ac84b05f-24a4-4a36-962c-f0b087ee5e34",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "d2e7239c-f87a-5baf-396a-d0c4a80410b8",
          "name": "Chamazulene [WHO-DD]",
          "stdName": "CHAMAZULENE [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "626b0792-091c-ecb0-2fd0-99793ce51161"
          ],
          "display_name": false
        },
        {
          "uuid": "7094bfca-aedc-476c-8379-33abbe39dae9",
          "name": "DIMETHULEN",
          "stdName": "DIMETHULEN",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8adf4313-feed-4078-9ae3-dab92571b90a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        },
        {
          "uuid": "c4ddb8c4-4e93-4c2a-8750-8e6bf29b3a85",
          "name": "DIMETHULENE",
          "stdName": "DIMETHULENE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8bde71d9-f621-47da-b757-d1784702509a",
            "b3dae390-5461-4266-93d8-4c873a7e5786"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "8bde71d9-f621-47da-b757-d1784702509a",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "b3dae390-5461-4266-93d8-4c873a7e5786",
          "citation": "MERCK INDEX",
          "doc_type": "MERCK INDEX",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ac84b05f-24a4-4a36-962c-f0b087ee5e34",
          "citation": "MERCK INDEX",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e8c73deb-2c13-4401-8db4-b4294299ad2d",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1cd75e77-6106-4489-89c1-ee134a5627e3",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8adf4313-feed-4078-9ae3-dab92571b90a",
          "citation": "SCIFINDER",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a5746776-3171-4028-b379-ce59b94c052c",
          "citation": "USP-DSC, VOL.2, 2015",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d2d0e690-b50e-4d6d-bb79-9a30ce7fca0e",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389665000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "192c84ef-428d-457b-9654-815ef9410ee3",
          "citation": "HERBAL MEDICINES 4TH ED 2103",
          "doc_type": "BOOK",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1db74e4a-d322-4226-a075-e5ff57706a7a",
          "citation": "SRS import [Z439UH6E5F]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=Z439UH6E5F",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389665000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c17fbc29-e855-4f8f-b5c5-1c1746967041",
          "citation": "CHAMAZULENE [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b62e6a9f-1258-41f6-8d1d-ca6f2bdb12d0",
          "citation": "CHAMAZULENE [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "7c5e6392-1be5-4c8d-899c-eb8875922c0a",
          "citation": "CHAMAZULENE [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "7bb6fced-1147-0c79-a025-a577dd64d659",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=529-05-5",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "2f3faeae-1f4c-4ce0-a4cf-ee86d4047550",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "626b0792-091c-ecb0-2fd0-99793ce51161",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "9092fea5-e55f-1fee-d578-b0284957a6d4",
          "citation": "EU-SRS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "e1f1662b-55af-4713-9879-662e0e630dc3",
          "id": "e1f1662b-55af-4713-9879-662e0e630dc3",
          "molfile": "\n  Marvin  01132111422D          \n\n 14 15  0  0  0  0            999 V2000\n    2.6913   -0.1835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.9808   -0.9540    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.4535   -1.5873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8076   -2.3371    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.4482   -3.0791    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6416   -3.2523    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4503   -4.0563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.0005   -2.7378    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.2120   -2.9886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.2715   -2.3164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.2198   -1.6494    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.0233   -0.8609    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.0057   -1.9183    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6494   -1.4090    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  4  3  1  0  0  0  0\n  3 14  2  0  0  0  0\n  5  4  2  0  0  0  0\n  5  6  1  0  0  0  0\n  7  6  1  0  0  0  0\n  6  8  2  0  0  0  0\n  9  8  1  0  0  0  0\n  8 13  1  0  0  0  0\n  9 10  2  0  0  0  0\n 10 11  1  0  0  0  0\n 12 11  1  0  0  0  0\n 11 13  2  0  0  0  0\n 14 13  1  0  0  0  0\nM  END",
          "smiles": "CCc1ccc(C)c-2ccc(C)c2c1",
          "formula": "C14H16",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "82e4ccd3-002b-4317-b1c5-5f2eadf01533"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "184.2774",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "d22589be-437b-4af0-964f-d8fd6958cb3f",
      "version": "13",
      "structure": {
        "id": "a5c797a9-33f7-4005-8647-a6d165a04395",
        "molfile": "\n  Marvin  01132108372D          \n\n 14 15  0  0  0  0            999 V2000\n    1.0057   -1.9183    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.0005   -2.7378    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.2120   -2.9886    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6494   -1.4090    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.2198   -1.6494    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6416   -3.2523    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.2715   -2.3164    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.4482   -3.0791    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.4535   -1.5873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8076   -2.3371    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.0233   -0.8609    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4503   -4.0563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.9808   -0.9540    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.6913   -0.1835    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  3  2  1  0  0  0  0\n  4  1  1  0  0  0  0\n  5  1  2  0  0  0  0\n  6  2  2  0  0  0  0\n  7  5  1  0  0  0  0\n  8  6  1  0  0  0  0\n  9  4  2  0  0  0  0\n 10  9  1  0  0  0  0\n 11  5  1  0  0  0  0\n 12  6  1  0  0  0  0\n 13  9  1  0  0  0  0\n 14 13  1  0  0  0  0\n  3  7  2  0  0  0  0\n  8 10  2  0  0  0  0\nM  END",
        "smiles": "CCc1ccc(C)c-2ccc(C)c2c1",
        "formula": "C14H16",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "184.2774",
        "optical_activity": "NONE",
        "references": [
          "1db74e4a-d322-4226-a075-e5ff57706a7a",
          "8bde71d9-f621-47da-b757-d1784702509a"
        ],
        "stereo_centers": 0
      },
      "unii": "Z439UH6E5F"
    }
  ]
}