{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "2a7dd3ab-e06b-4af8-ae9d-9e57dc460cc4",
          "code": "7440-21-3",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=7440-21-3",
          "code_system": "CAS",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2",
            "ad6521c8-fb81-4ff6-b072-2a97878d5692"
          ]
        },
        {
          "uuid": "a14b6d37-c388-4141-b000-a7172ea4d360",
          "code": "C84589",
          "type": "PRIMARY",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C84589",
          "code_system": "NCI_THESAURUS",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "cc7e0477-9b79-4604-820d-0e2965a79d0f",
          "code": "D012825",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/68012825",
          "code_system": "MESH",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "10f550b9-5064-4dae-95fd-53a25dc7c017",
          "code": "9774",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/9774/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "ef888458-9926-4151-9d6d-837dea34557f",
          "code": "m9900",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m9900?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "8062d7a7-83f0-4fdc-8be5-760344df9d5c",
          "code": "SUB126233",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "98f3ddaf-ad0f-4c6e-8607-c3c1c0863cc8",
          "code": "5461123",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/5461123",
          "code_system": "PUBCHEM",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "92d4860e-1698-4307-b67c-4c26142ba6f6",
          "code": "231-130-8",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.028.300",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "5fffcd3a-1756-4dad-aa0f-339309dc5fb2"
          ]
        },
        {
          "uuid": "ca2586e6-01c7-bbf7-d20f-d0a77c7bfd36",
          "code": "5033",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/source/hsdb/5033",
          "code_system": "HSDB",
          "references": [
            "c7318c53-34c6-7e47-b9a3-c5e98fb8d9e0"
          ]
        },
        {
          "uuid": "2c4dd744-c6a0-17b7-22f2-145000d6c1c6",
          "code": "DTXSID0051441",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID0051441",
          "code_system": "EPA CompTox",
          "references": [
            "a3ccf5ee-a5c0-5421-f9c5-e6257a4443ce"
          ]
        },
        {
          "uuid": "78cb614f-2b4a-4e22-f6d2-4e3926ae71a9",
          "code": "C1940",
          "comments": "Drug or Chemical by Structure[C1913]|Inorganic Chemical[C579]|Element",
          "type": "CONCEPT",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1940",
          "code_system": "NCI_THESAURUS",
          "references": [
            "6c87a010-56e9-51c2-6cbc-4e819b520c56"
          ]
        },
        {
          "uuid": "7c256f60-896d-b5fe-f24c-6a586fa4cd47",
          "code": "DB12982",
          "type": "PRIMARY",
          "url": "https://go.drugbank.com/drugs/DB12982",
          "code_system": "DRUG BANK",
          "references": [
            "6c87a010-56e9-51c2-6cbc-4e819b520c56"
          ]
        },
        {
          "uuid": "4533cc87-fcfd-4bbf-9f90-6f84be062088",
          "code": "Z4152N8IUI",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "3630c3ce-ddb2-9a67-3f21-c8f79ef61992",
          "code": "146 (Number of products:1149)",
          "comments": "Dietary Supplement Label Database|Mineral|Silicon",
          "type": "PRIMARY",
          "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=146&item=Silicon",
          "code_system": "DSLD",
          "references": [
            "6c87a010-56e9-51c2-6cbc-4e819b520c56"
          ]
        },
        {
          "uuid": "4f82d718-ef18-3475-a8f7-ad93d7df91ec",
          "code": "27573",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:27573",
          "code_system": "CHEBI",
          "references": [
            "6c87a010-56e9-51c2-6cbc-4e819b520c56"
          ]
        },
        {
          "uuid": "194b380d-41e5-4b29-eb72-fe773f1e1e1e",
          "code": "Z4152N8IUI",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=Z4152N8IUI",
          "code_system": "DAILYMED",
          "references": [
            "f811bd9c-9724-ec92-1b29-9355d53b515c"
          ]
        },
        {
          "uuid": "3bd1c096-ce8f-e5e8-560d-7ea99e72b24d",
          "code": "100000151810",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "327bb38b-b19c-4c96-93c7-2684258c10ff"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "4a0eea8f-add3-4adc-bf1e-5872b4f92335",
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "c370b924-7a11-442f-90ff-39b5811bce9c",
            "refuuid": "cc861294-f183-4874-9a67-f7f44e045901",
            "name": "SILICON",
            "unii": "Z4152N8IUI",
            "linking_id": "Z4152N8IUI",
            "ref_pname": "SILICON",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "ac51b206-b274-4077-a090-d7cce2876463",
          "name": "SILICON",
          "stdName": "SILICON",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "94b0b8be-11fc-43c8-9af5-391d720ed670",
            "a6b70120-d03f-459a-a981-bde99333fa1b",
            "d63fcd27-5864-4e8d-8ed6-d4f08231b775",
            "adee836d-c91e-4ad1-a540-866176b5d4d9",
            "4d5df745-bf74-4ea8-be09-79812a5d913e",
            "d15d478e-5588-4fd6-bfa0-2f88acbfca4f",
            "4af92f86-594a-49c4-a486-6a4eaa0c0da6",
            "843a7ef9-16fe-41c8-bc93-45e9e319635e",
            "a002c60d-ab34-40da-9e05-df9677c17467"
          ],
          "display_name": true
        },
        {
          "uuid": "ba41c6ab-7123-41f5-8de9-4dda28fe762e",
          "name": "SILICON [II]",
          "stdName": "SILICON [II]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "94b0b8be-11fc-43c8-9af5-391d720ed670"
          ],
          "display_name": false
        },
        {
          "uuid": "061f0fc3-25ae-40aa-a7db-da10de76517f",
          "name": "SILICON [MART.]",
          "stdName": "SILICON [MART.]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d15d478e-5588-4fd6-bfa0-2f88acbfca4f",
            "adee836d-c91e-4ad1-a540-866176b5d4d9"
          ],
          "display_name": false
        },
        {
          "uuid": "8ab3f24a-df57-492c-875e-fa66dbdfe1af",
          "name": "SILICON [MI]",
          "stdName": "SILICON [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d15d478e-5588-4fd6-bfa0-2f88acbfca4f",
            "4af92f86-594a-49c4-a486-6a4eaa0c0da6"
          ],
          "display_name": false
        },
        {
          "uuid": "792110c4-3754-4d3d-af14-e81bc1a4615c",
          "name": "SILICON, ELEMENTAL [HSDB]",
          "stdName": "SILICON, ELEMENTAL [HSDB]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c7e35c2e-9351-4e31-aae9-3012638ccf78",
            "d15d478e-5588-4fd6-bfa0-2f88acbfca4f"
          ],
          "display_name": false
        },
        {
          "uuid": "ac93ea32-b139-67a1-4715-46455d53a5ed",
          "name": "Silicon [WHO-DD]",
          "stdName": "SILICON [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4cb707d3-73ea-ebec-f45c-5dd16772de84"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "94b0b8be-11fc-43c8-9af5-391d720ed670",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "4af92f86-594a-49c4-a486-6a4eaa0c0da6",
          "citation": "MERCK INDEX",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d15d478e-5588-4fd6-bfa0-2f88acbfca4f",
          "citation": "MERCK INDEX",
          "doc_type": "MERCK INDEX",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "adee836d-c91e-4ad1-a540-866176b5d4d9",
          "citation": "MART",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c7e35c2e-9351-4e31-aae9-3012638ccf78",
          "citation": "HSDB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4d5df745-bf74-4ea8-be09-79812a5d913e",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "5fffcd3a-1756-4dad-aa0f-339309dc5fb2",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390779000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "bb7fa833-b14f-4c75-94b5-41401c9cca35",
          "citation": "SRS import [Z4152N8IUI]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=Z4152N8IUI",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390779000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "2d8e19b1-9802-4fe7-8429-ffd2ff165651",
          "citation": "Merck",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "843a7ef9-16fe-41c8-bc93-45e9e319635e",
          "citation": "SILICON [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "a6b70120-d03f-459a-a981-bde99333fa1b",
          "citation": "SILICON [MART.]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "a002c60d-ab34-40da-9e05-df9677c17467",
          "citation": "SILICON [II]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "d63fcd27-5864-4e8d-8ed6-d4f08231b775",
          "citation": "SILICON [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "c7318c53-34c6-7e47-b9a3-c5e98fb8d9e0",
          "citation": "WEBSITE",
          "url": "https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+7440-21-3",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a3ccf5ee-a5c0-5421-f9c5-e6257a4443ce",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=7440-21-3",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "6c87a010-56e9-51c2-6cbc-4e819b520c56",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "973f189c-cf08-f004-7678-2852c967cbff",
          "citation": "PCPC",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true
        },
        {
          "uuid": "ad6521c8-fb81-4ff6-b072-2a97878d5692",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "4cb707d3-73ea-ebec-f45c-5dd16772de84",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "f811bd9c-9724-ec92-1b29-9355d53b515c",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "327bb38b-b19c-4c96-93c7-2684258c10ff",
          "citation": "EU-SRS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "8d2bb397-852d-4857-9bf0-343e93800071",
          "id": "8d2bb397-852d-4857-9bf0-343e93800071",
          "molfile": "\n  Marvin  01132107202D          \n\n  1  0  0  0  0  0            999 V2000\n   10.0313   -5.9688    0.0000 Si  0  0  0  0  0 15  0  0  0  0  0  0\nM  END",
          "smiles": "[Si]",
          "formula": "Si",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "5d49cb5f-0656-44c2-9a5c-15ad5056b527"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "28.0854",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "cc861294-f183-4874-9a67-f7f44e045901",
      "version": "14",
      "structure": {
        "id": "86067585-4a14-4856-b569-d25e3056ca13",
        "molfile": "\n  Marvin  01132106572D          \n\n  1  0  0  0  0  0            999 V2000\n   10.0313   -5.9688    0.0000 Si  0  0  0  0  0 15  0  0  0  0  0  0\nM  END",
        "smiles": "[Si]",
        "formula": "Si",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "28.0854",
        "optical_activity": "NONE",
        "references": [
          "bb7fa833-b14f-4c75-94b5-41401c9cca35",
          "2d8e19b1-9802-4fe7-8429-ffd2ff165651"
        ],
        "stereo_centers": 0
      },
      "unii": "Z4152N8IUI"
    }
  ]
}