{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "f77962c8-c884-4495-8b26-09cf6a026829",
          "code": "2,5-XYLENOL",
          "comments": "JECFA|FUNCTIONAL CLASSIFICATION|Flavouring Agent",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=1688",
          "code_system": "JECFA EVALUATION",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039"
          ]
        },
        {
          "uuid": "a14d6213-52cb-4704-a0b2-04b15371c7e4",
          "code": "95-87-4",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=95-87-4",
          "code_system": "CAS",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039",
            "70913099-fb65-4c28-a41c-9854aff204a2"
          ]
        },
        {
          "uuid": "bd83c2a4-c844-4629-a18b-a6b776c1cb29",
          "code": "C048893",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67048893",
          "code_system": "MESH",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039"
          ]
        },
        {
          "uuid": "dae466e5-a8ca-4587-9f27-b79b5f629bad",
          "code": "m11549",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m11549?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039"
          ]
        },
        {
          "uuid": "a0974fed-c727-4cad-8148-63590a64f52a",
          "code": "202-461-5",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.002.238",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039"
          ]
        },
        {
          "uuid": "5dd80b46-faed-45ac-976c-4a7983e47e6d",
          "code": "7267",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/7267",
          "code_system": "PUBCHEM",
          "references": [
            "ea61e313-9bab-41d3-9297-8af7c503e039"
          ]
        },
        {
          "uuid": "bc0e2897-7236-9dba-d604-2db3b9089fd9",
          "code": "5296",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/source/hsdb/5296",
          "code_system": "HSDB",
          "references": [
            "e7f32644-1d33-29ce-1247-f508ae2b5a07"
          ]
        },
        {
          "uuid": "6d972aaf-5afd-1b94-04b7-26a244ac83ef",
          "code": "DTXSID6025145",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID6025145",
          "code_system": "EPA CompTox",
          "references": [
            "51b84aa3-9fd8-ad34-5867-949edc6f9591"
          ]
        },
        {
          "uuid": "8b26267d-4271-463a-85bb-0e10119b0f1d",
          "code": "XH3E3564KX",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "36124d78-fd7b-eb69-8bd4-2774901f8602",
          "code": "2599",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=2599",
          "code_system": "NSC",
          "references": [
            "54846d8b-e420-5560-a08a-c653b8e8910a"
          ]
        },
        {
          "uuid": "0459f1cf-a24f-876a-e5ba-e9586df1c333",
          "code": "585",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/585/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "acafee73-28af-29f5-bb27-5d5f87f9adba"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "8447460e-de57-4163-acb3-63f9a85a847c",
          "amount": {
            "uuid": "0238e92b-b8cc-43d5-8387-02eb2bacbee5",
            "units": "PERCENT PEAK AREA",
            "high_limit": 0.1
          },
          "qualification": "EP",
          "type": "PARENT->IMPURITY",
          "interaction_type": "CHROMATOGRAPHIC PURITY (GC)",
          "references": [
            "e7398da7-5181-77be-2454-650b71ef48e0"
          ],
          "related_substance": {
            "uuid": "52ceeabf-d8a2-4a35-8bfd-02352fa50f45",
            "refuuid": "95c83ad7-b9a9-40f8-8a14-1516cc7185d5",
            "name": "METACRESOL",
            "unii": "GGO4Y809LO",
            "linking_id": "GGO4Y809LO",
            "ref_pname": "METACRESOL",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "508c14e0-0e5a-4fa1-b7a3-afc86edd2ce4",
          "amount": {
            "uuid": "863d48bc-8006-4690-a298-4a6157201a92",
            "units": "PERCENT PEAK AREA",
            "high_limit": 0.1
          },
          "qualification": "EP",
          "type": "PARENT->IMPURITY",
          "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)",
          "references": [
            "594a4d4f-c22a-4ccd-908b-f08b2a291b9e"
          ],
          "related_substance": {
            "uuid": "23b7c029-e817-45cb-9eea-ebdc0aa23564",
            "refuuid": "8ecfdcef-89ad-450d-b082-b6dedb9f879c",
            "name": "GEMFIBROZIL",
            "unii": "Q8X02027X3",
            "linking_id": "Q8X02027X3",
            "ref_pname": "GEMFIBROZIL",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "48175553-f030-47bd-81c9-3bd3684ad76c",
          "name": "1-HYDROXY-2,5-DIMETHYLBENZENE",
          "stdName": "1-HYDROXY-2,5-DIMETHYLBENZENE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "54964eb2-b4ff-4466-873a-3bf417ff3ed0"
          ],
          "display_name": false
        },
        {
          "uuid": "f965d6ed-d8c4-4d7a-bb12-5ec148e4a54c",
          "name": "2,5-DIMETHYLPHENOL",
          "stdName": "2,5-DIMETHYLPHENOL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "1f07f9cb-8444-40d3-911b-56b1a9dc1380",
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "06ab2cff-dd73-4c53-af64-c4d436cc3286",
            "13c6e3e7-cede-46cb-9e99-23c164c4e5a7"
          ],
          "display_name": false
        },
        {
          "uuid": "ee591381-fa75-4dd6-b6fb-2d268f7b3ff9",
          "name": "2,5-DIMETHYLPHENOL [HSDB]",
          "stdName": "2,5-DIMETHYLPHENOL [HSDB]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "1f07f9cb-8444-40d3-911b-56b1a9dc1380",
            "4949701d-52b3-4e54-9566-38eb4d3dfca0"
          ],
          "display_name": false
        },
        {
          "uuid": "63d05f93-e40a-4783-9222-f3f5d96c813c",
          "name": "2,5-XYLENOL",
          "stdName": "2,5-XYLENOL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "54964eb2-b4ff-4466-873a-3bf417ff3ed0",
            "26c05e99-6033-47a7-85f1-821a5341e2af",
            "256c8aee-6c93-4f32-8cec-8a8b449888c9"
          ],
          "display_name": true
        },
        {
          "uuid": "feb9b6f8-d986-443a-9780-dcfb4bb5060b",
          "name": "2,5-XYLENOL [FHFI]",
          "stdName": "2,5-XYLENOL [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "256c8aee-6c93-4f32-8cec-8a8b449888c9"
          ],
          "display_name": false
        },
        {
          "uuid": "8b19acb7-4d0e-47dc-a967-9d4e194195f0",
          "name": "DIMETHYLPHENOL, 2,5-",
          "stdName": "DIMETHYLPHENOL, 2,5-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4f85e061-dd08-443f-952e-7ef49cafc019"
          ],
          "display_name": false
        },
        {
          "uuid": "b5693c7a-fe5b-4cbd-b280-7b61fbf55c27",
          "name": "FEMA NO. 3595",
          "stdName": "FEMA NO. 3595",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "6616c717-328f-41a5-9f48-49c436d89a16"
          ],
          "display_name": false
        },
        {
          "uuid": "13890e12-3d41-7c4e-2cf6-acc1ab671e50",
          "name": "GEMFIBROZIL IMPURITY A [EP IMPURITY]",
          "stdName": "GEMFIBROZIL IMPURITY A [EP IMPURITY]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "594a4d4f-c22a-4ccd-908b-f08b2a291b9e"
          ],
          "display_name": false
        },
        {
          "uuid": "a063b126-109b-21ba-ca30-0095e43dbce5",
          "name": "METACRESOL IMPURITY G [EP IMPURITY]",
          "stdName": "METACRESOL IMPURITY G [EP IMPURITY]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e7398da7-5181-77be-2454-650b71ef48e0"
          ],
          "display_name": false
        },
        {
          "uuid": "b895ca64-8b04-43fd-afbd-0d271f1fd575",
          "name": "NSC-2599",
          "stdName": "NSC-2599",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "54964eb2-b4ff-4466-873a-3bf417ff3ed0"
          ],
          "display_name": false
        },
        {
          "uuid": "1b53e533-c021-4a41-8614-71a65f58391f",
          "name": "PHENOL, 2,5-DIMETHYL-",
          "stdName": "PHENOL, 2,5-DIMETHYL-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "54964eb2-b4ff-4466-873a-3bf417ff3ed0"
          ],
          "display_name": false
        },
        {
          "uuid": "60bbbfad-b5ee-4ee7-af5b-3740676af51c",
          "name": "XYLENOL 2,5-DIMETHYLPHENOL",
          "stdName": "XYLENOL 2,5-DIMETHYLPHENOL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "b1ebbb6c-e253-402f-88cf-de338b699468",
            "4e3ce4c9-381b-43f2-b98e-9a660b0793e7"
          ],
          "display_name": false
        },
        {
          "uuid": "a7ebd21b-25bb-4cee-a0d0-b44f6229c108",
          "name": "XYLENOL 2,5-DIMETHYLPHENOL [MI]",
          "stdName": "XYLENOL 2,5-DIMETHYLPHENOL [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4949701d-52b3-4e54-9566-38eb4d3dfca0",
            "b1ebbb6c-e253-402f-88cf-de338b699468"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "e7398da7-5181-77be-2454-650b71ef48e0",
          "citation": "European Pharmacopoeia Online 9.8, Metacresol Monograph",
          "doc_type": "EP",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "70913099-fb65-4c28-a41c-9854aff204a2",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "4f85e061-dd08-443f-952e-7ef49cafc019",
          "citation": "ICSAS BATCH 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "6616c717-328f-41a5-9f48-49c436d89a16",
          "citation": "CHEMID 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "54964eb2-b4ff-4466-873a-3bf417ff3ed0",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4949701d-52b3-4e54-9566-38eb4d3dfca0",
          "citation": "CHEMID",
          "doc_type": "CHEMID",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "256c8aee-6c93-4f32-8cec-8a8b449888c9",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1f07f9cb-8444-40d3-911b-56b1a9dc1380",
          "citation": "HSDB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b1ebbb6c-e253-402f-88cf-de338b699468",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "06ab2cff-dd73-4c53-af64-c4d436cc3286",
          "citation": "TOX 21",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ea61e313-9bab-41d3-9297-8af7c503e039",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390927000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "880687b5-d3bd-4381-91e2-6ede433a4b61",
          "citation": "SRS import [XH3E3564KX]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=XH3E3564KX",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390927000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "26c05e99-6033-47a7-85f1-821a5341e2af",
          "citation": "2,5-XYLENOL [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "13c6e3e7-cede-46cb-9e99-23c164c4e5a7",
          "citation": "2,5-DIMETHYLPHENOL [HSDB]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "4e3ce4c9-381b-43f2-b98e-9a660b0793e7",
          "citation": "XYLENOL 2,5-DIMETHYLPHENOL [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "e7f32644-1d33-29ce-1247-f508ae2b5a07",
          "citation": "WEBSITE",
          "url": "https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+95-87-4",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "51b84aa3-9fd8-ad34-5867-949edc6f9591",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=95-87-4",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "594a4d4f-c22a-4ccd-908b-f08b2a291b9e",
          "citation": "EP 10.5",
          "doc_type": "EP",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "54846d8b-e420-5560-a08a-c653b8e8910a",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "acafee73-28af-29f5-bb27-5d5f87f9adba",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "438bd02d-8d24-47a3-9bdd-0417081c2d0f",
          "id": "438bd02d-8d24-47a3-9bdd-0417081c2d0f",
          "molfile": "\n  Marvin  01132103342D          \n\n  9  9  0  0  0  0            999 V2000\n    7.4019   -3.5005    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4019   -4.3292    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.1062   -4.7510    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.1062   -5.5757    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.3834   -5.9902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.3834   -6.8147    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.6792   -5.5604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.9558   -5.9716    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.6792   -4.7395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  2  3  1  0  0  0  0\n  9  2  2  0  0  0  0\n  4  3  2  0  0  0  0\n  5  4  1  0  0  0  0\n  5  6  1  0  0  0  0\n  7  5  2  0  0  0  0\n  7  8  1  0  0  0  0\n  7  9  1  0  0  0  0\nM  END",
          "smiles": "Cc1ccc(C)c(c1)O",
          "formula": "C8H10O",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "786978e6-cf94-42e3-9a9d-0e87c991961c"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "122.1647",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "b079732d-5a92-49a7-841f-6d8e561be66c",
      "version": "10",
      "structure": {
        "id": "5cd3f33c-752e-4882-b192-b5a15687e4ec",
        "molfile": "\n  Marvin  01132104482D          \n\n  9  9  0  0  0  0            999 V2000\n    6.6792   -5.5604    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.3834   -5.9902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.1062   -5.5757    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.1062   -4.7510    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4019   -4.3292    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.6792   -4.7395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4019   -3.5005    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.3834   -6.8147    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.9558   -5.9716    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  2  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  2  0  0  0  0\n  5  4  1  0  0  0  0\n  6  5  2  0  0  0  0\n  1  6  1  0  0  0  0\n  5  7  1  0  0  0  0\n  2  8  1  0  0  0  0\n  1  9  1  0  0  0  0\nM  END",
        "smiles": "Cc1ccc(C)c(c1)O",
        "formula": "C8H10O",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "122.1647",
        "optical_activity": "NONE",
        "references": [
          "880687b5-d3bd-4381-91e2-6ede433a4b61",
          "6616c717-328f-41a5-9f48-49c436d89a16"
        ],
        "stereo_centers": 0
      },
      "unii": "XH3E3564KX"
    }
  ]
}