{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "e008aabc-2694-44c5-a914-32e536b11818",
          "code": "P33681",
          "type": "PRIMARY",
          "url": "http://www.uniprot.org/uniprot/P33681",
          "code_system": "UNIPROT",
          "references": [
            "1d57e400-fad7-4a1f-b9f8-3ba1c8a212b1"
          ]
        },
        {
          "uuid": "3bbea3fc-49a0-492f-84a3-c1e01479fefa",
          "code": "P33681",
          "type": "PRIMARY",
          "url": "https://pharos.nih.gov/idg/search?q=P33681",
          "code_system": "PHAROS",
          "references": [
            "1d57e400-fad7-4a1f-b9f8-3ba1c8a212b1"
          ]
        },
        {
          "uuid": "f8a16588-87a2-43ff-a8c9-3df60e301aff",
          "code": "W6H7SY78HC",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        }
      ],
      "substance_class": "protein",
      "references": [
        {
          "uuid": "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
          "citation": "http://www.uniprot.org/uniprot/P33681",
          "url": "http://www.uniprot.org/uniprot/P33681",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd",
          "citation": "UNIPROT",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1d57e400-fad7-4a1f-b9f8-3ba1c8a212b1",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493394176000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "505e96c8-667a-4a9f-9454-200425c4234c",
          "citation": "https://www.drugbank.ca/drugs/DB01281#BE0000847",
          "doc_type": "WEBSITE",
          "public_domain": true
        },
        {
          "uuid": "64fe4668-df8e-4688-8e57-2745db925a31",
          "citation": "P33681",
          "url": "https://www.uniprot.org/uniprotkb/P33681",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f8822362-cd8e-454a-af6a-e51e25e14d8e",
          "citation": "Rilimogene Galvacirepvec/ MedNet",
          "doc_type": "INN",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f6bd927d-c62e-4788-a073-6302485ad905",
          "citation": "Rilimogene Galvacirepvec/ MedNet",
          "url": "https://www.cancer.gov/publications/dictionaries/cancer-drug/def/rilimogene-galvacirepvec-rilimogene-glafolivec",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "9b8efd29-02c2-4878-a8b3-ad6bc0d44349",
      "version": "12",
      "unii": "W6H7SY78HC",
      "relationships": [
        {
          "uuid": "b13b46dd-1400-4f3b-9ecb-68cc7f24984d",
          "amount": {
            "uuid": "6bbf09df-7723-431e-bbae-946ae8f1c98f"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "505e96c8-667a-4a9f-9454-200425c4234c"
          ],
          "related_substance": {
            "uuid": "f9b04f60-03cb-42d4-a31f-76a23c6c4773",
            "refuuid": "a595d37f-e739-4cd6-bc03-93219cc9c960",
            "name": "ABATACEPT",
            "unii": "7D0YB67S97",
            "linking_id": "7D0YB67S97",
            "ref_pname": "ABATACEPT"
          }
        },
        {
          "uuid": "545cfeca-367a-4a7a-9bb3-c9ec0e62abe4",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "992816d4-53dc-4f3f-af93-bcb68e1b8e16",
            "refuuid": "e334c15b-5170-4712-b9c4-6928f47f8121",
            "name": "GALIXIMAB",
            "unii": "S9OX9692ZB",
            "linking_id": "S9OX9692ZB",
            "ref_pname": "GALIXIMAB"
          }
        },
        {
          "uuid": "2b014c57-6106-4b25-a3ca-7bad42a634fd",
          "amount": {
            "uuid": "12c23c75-2410-41e2-a19e-a5b81385ccdf"
          },
          "type": "PARENT->DERIVATIVE",
          "references": [
            "64fe4668-df8e-4688-8e57-2745db925a31"
          ],
          "related_substance": {
            "uuid": "64357327-c84f-4131-8506-cf55c40e1b73",
            "refuuid": "6f5ac614-54ac-961e-6652-c18037971854",
            "name": "T-lymphocyte activation antigen CD80 preprotein",
            "unii": "APN8654GMB",
            "linking_id": "APN8654GMB",
            "ref_pname": "T-lymphocyte activation antigen CD80 preprotein",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "ddf9fa2d-659d-4b8f-8b67-b1f40f198911",
          "amount": {
            "uuid": "78b28f13-aa7a-4075-a236-345380c93a95"
          },
          "type": "VECTOR->EXPRESSED PROTEIN",
          "references": [
            "f6bd927d-c62e-4788-a073-6302485ad905"
          ],
          "related_substance": {
            "uuid": "22b95a77-4b5f-4dbe-aa14-f90a3591e39d",
            "refuuid": "d7d3d2e1-b7af-e0eb-e449-6f894f37e2d3",
            "name": "MVA-BN-BRACHYURY-TRICOM VACCINE",
            "unii": "GD1ZWN2I2Y",
            "linking_id": "GD1ZWN2I2Y",
            "ref_pname": "MVA-BN-BRACHYURY-TRICOM VACCINE",
            "substance_class": "reference"
          }
        }
      ],
      "names": [
        {
          "uuid": "9c790f1f-1e2c-4598-bd53-730ee00f5489",
          "name": "ACTIVATION B7-1 ANTIGEN",
          "stdName": "ACTIVATION B7-1 ANTIGEN",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "04a1d879-4d0b-4603-a1f9-00cb5c024b95",
          "name": "B7",
          "stdName": "B7",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "a8379773-0d2e-45d1-a7e9-441db0a94ebe",
          "name": "BB1",
          "stdName": "BB1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "16a1765a-39d9-4e87-97fb-61b75896b9b1",
          "name": "CD28LG",
          "stdName": "CD28LG",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "1736ba79-c5fe-45c0-ace5-a3d90454ebda",
          "name": "CD28LG1",
          "stdName": "CD28LG1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "88065140-5ebf-448c-aca9-5ff46c95dfe4",
          "name": "CD80",
          "stdName": "CD80",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "be5d15cf-1d0f-473a-8317-88f31a62cb24",
          "name": "CTLA-4 COUNTER-RECEPTOR B7.1",
          "stdName": "CTLA-4 COUNTER-RECEPTOR B7.1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "6bbc5363-a133-4398-b29a-846fe9c6acf0",
          "name": "LAB7",
          "stdName": "LAB7",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": false
        },
        {
          "uuid": "80156237-9c75-4e80-8aca-19ab809dbe36",
          "name": "T-LYMPHOCYTE ACTIVATION ANTIGEN CD80",
          "stdName": "T-LYMPHOCYTE ACTIVATION ANTIGEN CD80",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "46aac327-7fc1-4451-b4a8-e242a9f0dc9d",
            "c124d5c0-d8b4-42b7-bb60-f4dab058c7dd"
          ],
          "display_name": true
        }
      ],
      "protein": {
        "uuid": "7d64186d-7646-4392-98c5-eaa2ca7743bc",
        "glycosylation": {
          "uuid": "239c89fb-9c91-4f46-839d-31448d8599d2",
          "glycosylation_type": "HUMAN",
          "n_glycosylation_sites": [
            {
              "residue_index": 19,
              "subunit_index": 1
            },
            {
              "residue_index": 55,
              "subunit_index": 1
            },
            {
              "residue_index": 64,
              "subunit_index": 1
            },
            {
              "residue_index": 152,
              "subunit_index": 1
            },
            {
              "residue_index": 173,
              "subunit_index": 1
            },
            {
              "residue_index": 177,
              "subunit_index": 1
            },
            {
              "residue_index": 192,
              "subunit_index": 1
            },
            {
              "residue_index": 198,
              "subunit_index": 1
            },
            {
              "residue_index": 19,
              "subunit_index": 2
            },
            {
              "residue_index": 55,
              "subunit_index": 2
            },
            {
              "residue_index": 64,
              "subunit_index": 2
            },
            {
              "residue_index": 152,
              "subunit_index": 2
            },
            {
              "residue_index": 173,
              "subunit_index": 2
            },
            {
              "residue_index": 177,
              "subunit_index": 2
            },
            {
              "residue_index": 192,
              "subunit_index": 2
            },
            {
              "residue_index": 198,
              "subunit_index": 2
            }
          ]
        },
        "subunits": [
          {
            "uuid": "6b648a0b-a6cd-4b83-a22e-3ceae3f29dee",
            "sequence": "VIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV",
            "subunit_index": 1
          },
          {
            "uuid": "a4cc303e-4ea6-47a6-b843-a9f146be8121",
            "sequence": "VIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV",
            "subunit_index": 2
          }
        ],
        "references": [
          "46aac327-7fc1-4451-b4a8-e242a9f0dc9d"
        ],
        "disulfide_links": [
          {
            "sites": [
              {
                "residue_index": 16,
                "subunit_index": 1
              },
              {
                "residue_index": 82,
                "subunit_index": 1
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 16,
                "subunit_index": 2
              },
              {
                "residue_index": 82,
                "subunit_index": 2
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 128,
                "subunit_index": 1
              },
              {
                "residue_index": 182,
                "subunit_index": 1
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 128,
                "subunit_index": 2
              },
              {
                "residue_index": 182,
                "subunit_index": 2
              }
            ]
          }
        ],
        "protein_sub_type": "T-CELL ANTIGEN",
        "protein_type": "RECEPTOR",
        "sequence_origin": "HUMAN",
        "sequence_type": "COMPLETE"
      },
      "properties": [
        {
          "uuid": "1d060433-fa19-495b-b42f-c58a58d35679",
          "name": "MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)",
          "type": "amount",
          "value": {
            "uuid": "8da2e5cd-ace5-42c9-8643-ee6ae7bff23c",
            "type": "NUMBER AVERAGE",
            "average": 58623,
            "units": "DA",
            "non_numeric_value": "UNMODIFIED MW"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        },
        {
          "uuid": "78c5b8fd-6ffa-4102-b347-e7f5af3ba477",
          "name": "Molecular Formula",
          "value": {
            "uuid": "c6fd9213-7998-49bf-ac83-124270226885",
            "type": "ESTIMATED",
            "non_numeric_value": "C2604H4064N712O780P2S28"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "32af715d-8fa5-4798-a532-20bb5e221637",
        "structural_modifications": [
          {
            "uuid": "57792430-6001-47fd-86ab-85de4364dc60",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 250,
                "subunit_index": 1
              },
              {
                "residue_index": 250,
                "subunit_index": 2
              }
            ],
            "molecular_fragment": {
              "uuid": "fa3e882d-be1d-4a45-8ae9-c7f3519b4452",
              "refuuid": "b6eb2edb-1b4d-46ad-92ad-a43f0f545926",
              "name": "DEXFOSFOSERINE",
              "unii": "VI4F0K069V",
              "linking_id": "VI4F0K069V",
              "ref_pname": "DEXFOSFOSERINE",
              "substance_class": "reference"
            },
            "residue_modified": "SERINE",
            "structural_modification_type": "AMINO ACID REPLACEMENT"
          }
        ]
      }
    }
  ]
}