{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "polymer": {
        "uuid": "f1e40a0f-abfe-c5a8-e180-d1204a33a8c2",
        "classification": {
          "uuid": "fedefeb8-e423-08e4-b08f-76bb1d1d34e0",
          "parent_substance": {
            "uuid": "2f96c997-272e-4f91-925e-6deca1a92da9",
            "refuuid": "8993eee6-a544-48f0-923c-baf1650a9004",
            "name": "COTTON FIBER",
            "references": [],
            "unii": "70LDW53ROO",
            "linking_id": "70LDW53ROO",
            "ref_pname": "COTTON FIBER",
            "substance_class": "reference"
          },
          "polymer_class": "HOMOPOLYMER",
          "polymer_geometry": "LINEAR",
          "polymer_subclass": [
            "SUBSTITUTED"
          ],
          "source_type": "BIOSYNTHETIC"
        },
        "monomers": [
          {
            "uuid": "c0cee530-e3df-aa78-e921-f99e2ea03327",
            "amount": {
              "uuid": "804a570c-d6a2-c9cb-e877-e89293577d2e"
            },
            "type": "MONOMER",
            "defining": false,
            "monomer_substance": {
              "uuid": "699dfec1-8850-9469-ef20-3145404951fc",
              "refuuid": "4cf90035-16a7-4b50-b45c-fc1451b122d2",
              "name": ".BETA.-D-GLUCOPYRANOSE",
              "linking_id": "J4R00M814D",
              "ref_pname": ".BETA.-D-GLUCOPYRANOSE",
              "substance_class": "reference",
              "unii": "J4R00M814D"
            }
          },
          {
            "uuid": "a1fe33a2-51f2-487c-b605-220e1ec570bc",
            "type": "SUBSTITUENT",
            "defining": false,
            "monomer_substance": {
              "uuid": "9faf8482-9a3b-4562-b94d-f0869c8dca02",
              "refuuid": "fa076cc4-0e8d-4b65-aef5-cf1e95e2659e",
              "name": "PROPYLENE OXIDE",
              "linking_id": "Y4Y7NYD4BK",
              "ref_pname": "PROPYLENE OXIDE",
              "substance_class": "reference",
              "unii": "Y4Y7NYD4BK"
            }
          }
        ],
        "references": [
          "18aa7736-f36c-ee27-c5f6-af9de755a3b4"
        ],
        "display_structure": {
          "id": "01585cac-6009-4a8b-8062-fad6b2fcef43",
          "molfile": "\n  Marvin  01132105372D          \n\n 24 22  0  0  1  0            999 V2000\n   19.8136  -10.2133    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0\n   20.6346  -10.2133    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   22.2232   -4.4723    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   20.5750   -4.4714    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   19.7542   -3.0457    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   21.8172   -2.3320    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   22.2302   -3.0512    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0\n   21.8160   -3.7648    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n   20.9888   -3.7648    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0\n   20.5819   -3.0457    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n   20.9958   -2.3320    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n   20.5824   -1.6137    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.6339   -2.3439    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0\n   17.8966   -3.0457    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   25.0722   -3.0512    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   20.9918   -0.9003    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   21.8130   -0.9003    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   20.9780   -5.1761    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   21.8038   -5.1807    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   20.3049   -7.8144    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   21.0149   -7.3994    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   21.7254   -7.8098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.4357   -7.3948    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   21.0149   -6.5783    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  6  7  1  0  0  0  0\n  7  8  1  0  0  0  0\n  8  3  1  6  0  0  0\n  8  9  1  0  0  0  0\n  9  4  1  1  0  0  0\n  9 10  1  0  0  0  0\n 10  5  1  6  0  0  0\n 10 11  1  0  0  0  0\n 11  6  1  0  0  0  0\n 11 12  1  1  0  0  0\n  7 13  1  6  0  0  0\n  5 14  1  0  0  0  0\n  7 15  1  0  0  0  0\n 12 16  1  0  0  0  0\n 16 17  1  0  0  0  0\n  4 18  1  0  0  0  0\n  3 19  1  0  0  0  0\n 20 21  1  0  0  0  0\n 21 22  1  0  0  0  0\n 22 23  1  0  0  0  0\n 21 24  1  0  0  0  0\nM  STY  3   1 GEN   2 GEN   3 SRU\nM  SAL   1  2   1   2\nM  SDI   1  4   19.3936  -10.6333   19.3936   -9.7933\nM  SDI   1  4   21.0546   -9.7933   21.0546  -10.6333\nM  SAL   2  5  20  21  22  23  24\nM  SDI   2  4   19.8849   -8.2344   19.8849   -6.1583\nM  SDI   2  4   22.8557   -6.1583   22.8557   -8.2344\nM  SAL   3 15   3   4   5   6   7   8   9  10  11  12  13  16  17  18  19\nM  SDI   3  4   19.3342   -5.6007   19.3342   -0.4803\nM  SDI   3  4   23.0539   -0.4803   23.0539   -5.6007\nM  END",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "EPIMERIC",
          "defined_stereo": 5,
          "ez_centers": 0,
          "molecular_weight": 219.2122,
          "optical_activity": "UNSPECIFIED",
          "stereo_centers": 6
        },
        "idealized_structure": {
          "id": "6c295c80-0625-4262-8e24-df80cab34fc6",
          "molfile": "\n   JSDraw209232215132D\n\n 27 24  0  0  1  0              0 V2000\n   30.3703  -19.1420    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0\n   31.9203  -19.1420    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   34.9203   -8.3040    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   31.8083   -8.3020    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   30.2583   -5.6100    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   34.1533   -4.2630    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   34.9333   -5.6210    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   34.1513   -6.9680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   32.5893   -6.9680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   31.8213   -5.6100    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   32.6023   -4.2630    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   31.8223   -2.9070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   35.6953   -4.2850    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0\n   28.0493   -5.6100    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   37.9733   -5.6210    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   32.5953   -1.5600    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   34.1453   -1.5600    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   32.5693   -9.6320    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   34.1283   -9.6410    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   33.1573  -15.3720    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   33.0983  -13.8210    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   34.4143  -13.0030    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   36.4053  -13.7290    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   31.7313  -13.0900    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   29.3453  -14.2170    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n   35.9733  -18.5310    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   37.5313  -18.5310    0.0000 *   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  6  7  1  0  0  0  0\n  7  8  1  0  0  0  0\n  8  3  1  6  0  0  0\n  8  9  1  0  0  0  0\n  9  4  1  1  0  0  0\n  9 10  1  0  0  0  0\n 10  5  1  6  0  0  0\n 10 11  1  0  0  0  0\n 11  6  1  0  0  0  0\n 11 12  1  1  0  0  0\n  7 13  1  6  0  0  0\n  5 14  1  0  0  0  0\n  7 15  1  0  0  0  0\n 12 16  1  0  0  0  0\n 16 17  1  0  0  0  0\n  4 18  1  0  0  0  0\n  3 19  1  0  0  0  0\n 20 21  1  0  0  0  0\n 21 22  1  0  0  0  0\n 22 23  1  0  0  0  0\n 21 24  1  0  0  0  0\n 24 25  1  0  0  0  0\n 26 27  1  0  0  0  0\nM  STY  1   1 SRU\nM  SAL   1  8   3   4   5   6   7   8   9  10\nM  SAL   1  7  11  12  13  16  17  18  19\nM  SBL   1  2  13  14\nM  SMT   1 A\nM  SDI   1  4   29.2903   -6.3040   29.2903   -4.7850\nM  SDI   1  4   36.2013   -4.7850   36.2013   -6.3040\nM  STY  1   2 SRU\nM  SAL   2  4  20  21  22  24\nM  SBL   2  2  21  23\nM  SMT   2 B\nM  SDI   2  4   31.0363  -14.0510   31.0363  -12.5320\nM  SDI   2  4   35.1373  -12.5320   35.1373  -14.0510\nM  END",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "EPIMERIC",
          "references": [],
          "defined_stereo": 5,
          "ez_centers": 0,
          "molecular_weight": 235.2116,
          "optical_activity": "UNSPECIFIED",
          "stereo_centers": 6
        }
      },
      "codes": [
        {
          "uuid": "f3cf747a-778f-76fe-bc0d-a8fd638ab485",
          "code": "300000032771",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "16cd1a4d-6f7e-0739-3020-3f06102c6941"
          ]
        },
        {
          "uuid": "30053606-b6c8-d5f5-eeb0-7753742a4138",
          "code": "9004-64-2",
          "type": "GENERIC (FAMILY)",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=9004-64-2",
          "code_system": "CAS",
          "references": [
            "9474c74a-a632-35e5-ca48-9d23a26f1ba4"
          ]
        },
        {
          "uuid": "872c157e-c130-c12c-8de5-ebc962f488a4",
          "code": "VQ8ZWO78F6",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=VQ8ZWO78F6",
          "code_system": "DAILYMED",
          "references": [
            "091bdb65-89da-9153-18d1-2ca53c842c77"
          ]
        },
        {
          "uuid": "cab84402-e7cf-4680-914b-f3b2498f63e5",
          "code": "VQ8ZWO78F6",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        }
      ],
      "substance_class": "polymer",
      "notes": [
        {
          "note": "This is an incomplete polymer record. A more detailed definition may be available soon.",
          "references": [],
          "uuid": null
        }
      ],
      "references": [
        {
          "uuid": "8d706397-986e-7f8c-f7da-8ac6e9df0e0c",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "9474c74a-a632-35e5-ca48-9d23a26f1ba4",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "18aa7736-f36c-ee27-c5f6-af9de755a3b4",
          "citation": "MANUFACTURER PRODUCT DESCRIPTION",
          "doc_type": "MANUFACTURER PRODUCT DESCRIPTION",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f3f1968d-b69b-30af-b075-f92a62ee9c43",
          "citation": "NISSO",
          "doc_type": "MANUFACTURER PRODUCT DESCRIPTION",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a6c97c60-e7fa-4342-a8ad-de9dfc3b4a2f",
          "citation": "A li i S di f L HPC d HPMCASApplication Studies of L-HPC and HPMCAS for Pharmaceutical Dosage Forms U d t- Update -",
          "url": "https://ipecamericas.org/sites/default/files/ef12april24-hall.b%235-sakae.obara(shin-etsu).pdf",
          "doc_type": "MANUFACTURER PRODUCT DESCRIPTION",
          "public_domain": true
        },
        {
          "uuid": "400e7058-2ee5-4f25-b2ff-8a7340559876",
          "citation": "Klucel™ hydroxypropylcellulose Physical and chemical properties",
          "url": "https://www.ashland.com/file_source/Ashland/Product/Documents/Pharmaceutical/PC_11229_Klucel_HPC.pdf",
          "doc_type": "MANUFACTURER PRODUCT DESCRIPTION",
          "public_domain": true
        },
        {
          "uuid": "091bdb65-89da-9153-18d1-2ca53c842c77",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "16cd1a4d-6f7e-0739-3020-3f06102c6941",
          "citation": "SMS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "INCOMPLETE",
      "uuid": "0f86393a-e7eb-00ea-2739-a81ac1a9e399",
      "version": "27",
      "unii": "VQ8ZWO78F6",
      "relationships": [
        {
          "uuid": "ed898f22-d2ce-3d66-9345-eeaafa647964",
          "amount": {
            "uuid": "054fcb30-8bc8-4ba4-8e13-070d6259b8c0"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "d45dec86-9c68-679d-148c-0d41dac74bf8",
            "refuuid": "0f86393a-e7eb-00ea-2739-a81ac1a9e399",
            "name": "HYDROXYPROPYL CELLULOSE (430000 WAMW)",
            "unii": "VQ8ZWO78F6",
            "linking_id": "VQ8ZWO78F6",
            "ref_pname": "HYDROXYPROPYL CELLULOSE (430000 WAMW)",
            "substance_class": "reference"
          }
        }
      ],
      "names": [
        {
          "uuid": "d18ab543-715c-47ab-fa92-ebc349deb357",
          "name": "HYDROXYPROPYL CELLULOSE (410000-450000 WAMW)",
          "stdName": "HYDROXYPROPYL CELLULOSE (410000-450000 WAMW)",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8d706397-986e-7f8c-f7da-8ac6e9df0e0c"
          ],
          "display_name": false
        },
        {
          "uuid": "b131e300-36a3-66e1-97fe-8326fff220dc",
          "name": "HYDROXYPROPYL CELLULOSE (430000 WAMW)",
          "stdName": "HYDROXYPROPYL CELLULOSE (430000 WAMW)",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "18aa7736-f36c-ee27-c5f6-af9de755a3b4"
          ],
          "display_name": true
        },
        {
          "uuid": "296e1016-74f7-8a72-ea63-9b0311937f72",
          "name": "KLUCEL GF",
          "stdName": "KLUCEL GF",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "18aa7736-f36c-ee27-c5f6-af9de755a3b4"
          ],
          "display_name": false
        },
        {
          "uuid": "309c674b-d791-0d35-c251-19685615e9ad",
          "name": "KLUCEL GXF",
          "stdName": "KLUCEL GXF",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "18aa7736-f36c-ee27-c5f6-af9de755a3b4"
          ],
          "display_name": false
        },
        {
          "uuid": "00e73800-8053-12dd-c41a-d715937aea6f",
          "name": "NISSO HPC M",
          "stdName": "NISSO HPC M",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f3f1968d-b69b-30af-b075-f92a62ee9c43"
          ],
          "display_name": false
        }
      ],
      "properties": [
        {
          "uuid": "256a2257-6df8-c002-2920-09f81d0e5242",
          "name": "MOL_WEIGHT:WEIGHT AVERAGE",
          "type": "amount",
          "defining": true,
          "property_type": "CHEMICAL",
          "references": [
            "18aa7736-f36c-ee27-c5f6-af9de755a3b4"
          ]
        },
        {
          "uuid": "d072e9cc-45d7-4b25-aa96-932ab47a21f2",
          "name": "MOLAR SUBSTITUTION",
          "referencedSubstance": {
            "uuid": "1e509b63-a80b-4732-a039-eb2ad35a31cf",
            "refPname": "HYDROXYPROPYL FRAGMENT",
            "refuuid": "74c604e6-0900-42f1-9627-a189b7c3c4ab",
            "substanceClass": "reference",
            "linkingID": "74c604e6-0900-42f1-9627-a189b7c3c4ab",
            "name": "HYDROXYPROPYL FRAGMENT",
            "references": []
          },
          "defining": false,
          "property_type": "CHEMICAL",
          "references": [
            "400e7058-2ee5-4f25-b2ff-8a7340559876"
          ]
        },
        {
          "uuid": "f5990c4b-e338-4e47-9de2-b7d38a44ee29",
          "name": "DEGREE OF SUBSTITUTION",
          "referencedSubstance": {
            "uuid": "62b700f0-0503-4811-8d07-da6876e820d2",
            "refPname": "HYDROXYPROPYL FRAGMENT",
            "refuuid": "74c604e6-0900-42f1-9627-a189b7c3c4ab",
            "substanceClass": "reference",
            "linkingID": "74c604e6-0900-42f1-9627-a189b7c3c4ab",
            "name": "HYDROXYPROPYL FRAGMENT",
            "references": []
          },
          "defining": false,
          "property_type": "CHEMICAL",
          "references": [
            "a6c97c60-e7fa-4342-a8ad-de9dfc3b4a2f"
          ]
        },
        {
          "uuid": "250a9f95-c9ab-4a70-ab77-a1a6ba2546a8",
          "name": "VISCOSITY:DYNAMIC",
          "defining": false,
          "parameters": [
            {
              "uuid": "8c448347-b65a-496e-89b5-b6f715227323",
              "name": "Content",
              "type": "CHEMICAL",
              "value": {
                "uuid": "9ffe4419-737d-493c-aaa2-06b008bb99be",
                "type": "WEIGHT PERCENT",
                "average": 2,
                "units": "%",
                "references": [],
                "non_numeric_value": "in water"
              },
              "references": []
            },
            {
              "uuid": "e7151309-d376-486d-8bb9-36be80f42a57",
              "name": "Temperature",
              "type": "PHYSICAL",
              "value": {
                "uuid": "eb60278d-fc56-4810-9012-da34a13f6930",
                "type": "EXACT",
                "average": 25,
                "units": "°C",
                "references": []
              },
              "references": []
            }
          ],
          "property_type": "PHYSICAL"
        },
        {
          "uuid": "8d1ad448-f73d-4985-8506-bcac44e68657",
          "name": "MOL_WEIGHT:NUMBER AVERAGE",
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "fd9aac71-f136-6fad-e78f-871e2b6ddf19"
      }
    }
  ]
}