{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "c1ce361a-7950-4069-bd6b-ff98e44b2c02",
          "code": "2,5-DIMETHYLPYRAZINE",
          "comments": "JECFA|FUNCTIONAL CLASSIFICATION|Flavouring Agent",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=4108",
          "code_system": "JECFA EVALUATION",
          "references": [
            "00f0c988-af9d-4cbb-85ac-1f17b58a377b"
          ]
        },
        {
          "uuid": "95fdf482-7991-43e3-86f9-7e17e1c5eeff",
          "code": "123-32-0",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=123-32-0",
          "code_system": "CAS",
          "references": [
            "00f0c988-af9d-4cbb-85ac-1f17b58a377b",
            "f9270746-ec2d-4fc8-a461-33c575079e22"
          ]
        },
        {
          "uuid": "576de93f-8f03-4402-a1f1-49f281cb33fa",
          "code": "204-618-3",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.004.200",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "00f0c988-af9d-4cbb-85ac-1f17b58a377b"
          ]
        },
        {
          "uuid": "7df15002-f17f-4673-893f-96a2f57fde90",
          "code": "31252",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/31252",
          "code_system": "PUBCHEM",
          "references": [
            "00f0c988-af9d-4cbb-85ac-1f17b58a377b"
          ]
        },
        {
          "uuid": "b38a184b-1df8-2a58-c3c9-1e19d47f8a4f",
          "code": "DTXSID6047652",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID6047652",
          "code_system": "EPA CompTox",
          "references": [
            "873d3989-cd9a-ab98-ce47-d291fa9139bb"
          ]
        },
        {
          "uuid": "ac5708b7-00a9-43b8-99ae-0fc74587165b",
          "code": "V99Y0MUY1Q",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "dd91516b-e786-3c80-fd70-fa7dc1891553",
          "code": "49139",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=49139",
          "code_system": "NSC",
          "references": [
            "2d79b08d-f655-a83e-9c32-d28bed0c8100"
          ]
        },
        {
          "uuid": "e1412362-8915-cf30-e3f2-6901fbd854f2",
          "code": "841",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/841/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "a7dda6b4-85e7-8847-7211-0923fce028bf"
          ]
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "e556f27b-8ab6-4998-acdd-0a9c7196537a",
          "name": "2,5-DIMETHYL-1,4-DIAZINE",
          "stdName": "2,5-DIMETHYL-1,4-DIAZINE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f878b119-56da-4ab5-898d-bd31838d416b",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        },
        {
          "uuid": "0b41ebcd-8a41-4777-a8ea-c242e5eb9401",
          "name": "2,5-DIMETHYLPYRAZINE",
          "stdName": "2,5-DIMETHYLPYRAZINE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f878b119-56da-4ab5-898d-bd31838d416b",
            "59eedd20-654e-489a-8bfd-dcd8aac3f993",
            "98460e75-32dd-416d-8f1f-0178d6c407fb",
            "40223a2f-94c6-4804-89a6-421571fcd289",
            "02354106-1fc3-436b-b065-16122d5c24ae",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": true
        },
        {
          "uuid": "c1d75bb8-4e6e-4a0e-891a-47a41dcb078b",
          "name": "2,5-DIMETHYLPYRAZINE [FCC]",
          "stdName": "2,5-DIMETHYLPYRAZINE [FCC]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "02354106-1fc3-436b-b065-16122d5c24ae",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        },
        {
          "uuid": "faba924b-0e8d-44a9-a1b0-fd95b402ccc0",
          "name": "2,5-DIMETHYLPYRAZINE [FHFI]",
          "stdName": "2,5-DIMETHYLPYRAZINE [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "98460e75-32dd-416d-8f1f-0178d6c407fb",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        },
        {
          "uuid": "8445e810-2626-493d-ae53-74761968c74f",
          "name": "FEMA NO. 3272",
          "stdName": "FEMA NO. 3272",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "744fbcf2-7023-4232-b37f-d75326914720"
          ],
          "display_name": false
        },
        {
          "uuid": "628b17f4-bb42-4a95-8577-86f40901715c",
          "name": "KETINE",
          "stdName": "KETINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f878b119-56da-4ab5-898d-bd31838d416b",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        },
        {
          "uuid": "f9797ca2-fe31-41a8-8115-35a4e848ac01",
          "name": "NSC-49139",
          "stdName": "NSC-49139",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "19d4788f-f2b8-46f5-811f-e389933a355a",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        },
        {
          "uuid": "d6f9761e-0497-4b40-9423-95c57eba91d9",
          "name": "PYRAZINE, 2,5-DIMETHYL",
          "stdName": "PYRAZINE, 2,5-DIMETHYL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "1405a9fc-4eac-4413-9dd0-1646a4eca866",
            "c313171b-c40a-460c-a561-d92647f83d6c"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "f878b119-56da-4ab5-898d-bd31838d416b",
          "citation": "DOSE",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "c313171b-c40a-460c-a561-d92647f83d6c",
          "citation": "DOSE",
          "doc_type": "DOSE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1405a9fc-4eac-4413-9dd0-1646a4eca866",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "744fbcf2-7023-4232-b37f-d75326914720",
          "citation": "CHEMID 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "98460e75-32dd-416d-8f1f-0178d6c407fb",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "02354106-1fc3-436b-b065-16122d5c24ae",
          "citation": "FCC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "19d4788f-f2b8-46f5-811f-e389933a355a",
          "citation": "SCIFINDER",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "00f0c988-af9d-4cbb-85ac-1f17b58a377b",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390840000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3eb997ee-cbe0-41e8-8526-88b14b7ccc69",
          "citation": "AN OVERVIEW OF THE EFFECTS OF TOBACCO INGREDIENTS ON SMOKE CHEMISTRY AND TOXICITY; FOOD AND CHEMICAL TOXICOLOGY; BAKER, RR; 42(SUPPL):53-83, 2004",
          "url": "http://www.sciencedirect.com/science/article/pii/S0278691504000043",
          "doc_type": "JOURNAL ARTICLE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "5606bdf7-71d6-4805-9a64-b65e6c33ded4",
          "citation": "SRS import [V99Y0MUY1Q]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=V99Y0MUY1Q",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390840000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "39fede4a-7247-4ad9-b9ae-f446c16e3546",
          "citation": "ChemID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "40223a2f-94c6-4804-89a6-421571fcd289",
          "citation": "2,5-DIMETHYLPYRAZINE [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "59eedd20-654e-489a-8bfd-dcd8aac3f993",
          "citation": "2,5-DIMETHYLPYRAZINE [FCC]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "873d3989-cd9a-ab98-ce47-d291fa9139bb",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=123-32-0",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "2d79b08d-f655-a83e-9c32-d28bed0c8100",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "f9270746-ec2d-4fc8-a461-33c575079e22",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "a7dda6b4-85e7-8847-7211-0923fce028bf",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "ad69e573-a7b3-4331-9ad0-47038da8fd90",
          "id": "ad69e573-a7b3-4331-9ad0-47038da8fd90",
          "molfile": "\n  Marvin  01132109002D          \n\n  8  8  0  0  0  0            999 V2000\n    4.4224   -6.3898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.1136   -6.8402    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.0691   -7.6641    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.7604   -8.1144    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    6.4962   -7.7409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.1873   -8.1914    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.5405   -6.9172    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8493   -6.4667    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  3  2  1  0  0  0  0\n  2  8  2  0  0  0  0\n  4  3  2  0  0  0  0\n  5  4  1  0  0  0  0\n  5  6  1  0  0  0  0\n  7  5  2  0  0  0  0\n  8  7  1  0  0  0  0\nM  END",
          "smiles": "Cc1cnc(C)cn1",
          "formula": "C6H8N2",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "ccf7b2b3-7e9f-47a2-b43e-2e7f15ef3fe8"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "108.1413",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "00e76edc-13de-4170-abd8-790f8fd9cab9",
      "version": "5",
      "structure": {
        "id": "b539faca-c833-4353-879e-47c540153a59",
        "molfile": "\n  Marvin  01132109232D          \n\n  8  8  0  0  0  0            999 V2000\n    4.4224   -6.3898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.1136   -6.8402    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8493   -6.4667    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    6.5405   -6.9172    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.4962   -7.7409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.1873   -8.1914    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.7604   -8.1144    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    5.0691   -7.6641    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  2  3  2  0  0  0  0\n  3  4  1  0  0  0  0\n  4  5  2  0  0  0  0\n  5  6  1  0  0  0  0\n  5  7  1  0  0  0  0\n  7  8  2  0  0  0  0\n  8  2  1  0  0  0  0\nM  END",
        "smiles": "Cc1cnc(C)cn1",
        "formula": "C6H8N2",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "108.1413",
        "optical_activity": "NONE",
        "references": [
          "5606bdf7-71d6-4805-9a64-b65e6c33ded4",
          "39fede4a-7247-4ad9-b9ae-f446c16e3546"
        ],
        "stereo_centers": 0
      },
      "unii": "V99Y0MUY1Q"
    }
  ]
}