{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "6f99b48e-11d6-43de-81a6-32047db2c3e3",
          "code": "21 CFR 172.510",
          "comments": "PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION|Subpart F--Flavoring Agents and Related Substances|Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=172.510",
          "code_system": "CFR",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "7d7c82e0-677e-4dcb-8f8a-21a83704fb8b",
          "code": "28",
          "comments": "LiverTox|HDS: Herbal|Laxative|Aloe vera",
          "type": "PRIMARY",
          "url": "https://livertox.nlm.nih.gov/Aloe.htm",
          "code_system": "LIVERTOX",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "7ff9d243-b050-4593-a508-dbeb3bea187d",
          "code": "ALOE (FINALIZED)",
          "comments": "EMA Herbal Substance|",
          "type": "PRIMARY",
          "url": "http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/herbal/medicines/herbal_med_000011.jsp&mid=WC0b01ac058001fa1d",
          "code_system": "EPA PESTICIDE CODE",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "d44b2c47-7074-45b2-9d20-cee78b091262",
          "code": "91263",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/91263/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "96e8d1a0-24b7-4542-86fa-64da41ad7586",
          "code": "m1569",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m1569?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "0812e7a7-a1fe-4d6f-8eec-cbabd6366ec3",
          "code": "SUB37102",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "2406afaf-49d8-4d53-9858-1b44c02449fa",
          "code": "CHEMBL2108221",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL2108221",
          "code_system": "ChEMBL",
          "references": [
            "dfa99df8-2e7b-4f97-9d57-ddb80e818143"
          ]
        },
        {
          "uuid": "b7e82cc1-d5ac-5fa0-54e6-0b5dda0ba763",
          "code": "Aloe",
          "type": "PRIMARY",
          "url": "https://www.ncbi.nlm.nih.gov/books/n/lactmed/LM915/",
          "code_system": "LACTMED",
          "references": [
            "05dc941e-3abf-a89e-07f8-67f40482e7c7"
          ]
        },
        {
          "uuid": "434efc92-015b-9432-f74c-542411fc1225",
          "code": "6 (Number of products:524)",
          "comments": "Dietary Supplement Label Database|Botanical|Aloe",
          "type": "PRIMARY",
          "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=6&item=Aloe",
          "code_system": "DSLD",
          "references": [
            "05dc941e-3abf-a89e-07f8-67f40482e7c7"
          ]
        },
        {
          "uuid": "2a39bcbe-c5cc-4121-9cb4-f107065dfbd8",
          "code": "V5VD430YW9",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "41478f7c-112b-a303-305e-7409fdb319e3",
          "code": "V5VD430YW9",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=V5VD430YW9",
          "code_system": "DAILYMED",
          "references": [
            "edce0ed3-560f-f514-f9a3-9e0122a2ea1a"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "2afcebe6-6084-417e-ba34-1cf96ea00dd7",
          "amount": {
            "uuid": "a41fca5d-98f6-49f8-be99-c315fa140bac"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "7e2fa412-e258-455d-8319-f00a21ba8ef2",
            "refuuid": "78173142-8aa6-4487-b293-935aa058de79",
            "name": "ALOE",
            "unii": "V5VD430YW9",
            "linking_id": "V5VD430YW9",
            "ref_pname": "ALOE",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "mixture",
      "names": [
        {
          "uuid": "a9b2c9ba-735a-46ca-bb33-56d47d4398ec",
          "name": "ALOE",
          "stdName": "ALOE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "b0635687-bb33-44ce-a1af-8cc2c803e1fd",
            "d08c8b5b-2b25-4baf-9c45-ffa3ee220da1",
            "576472af-419a-4969-b2c8-71f6ba2d57dd",
            "3c1ff4e0-c602-4bc9-b0e3-2d9c4bfda3c4",
            "08a05c28-6bb8-497c-99d9-3c9d578e53b2",
            "293f149f-db68-4f1b-a741-381273364657",
            "0e8098e1-ee38-4c84-8bf6-012635462eca",
            "b4370f19-d19c-410a-9844-272a9d4bf993",
            "173b8432-9f63-4372-adf2-4543b9391ba8"
          ],
          "display_name": true
        },
        {
          "uuid": "a21a72c9-1f5f-42d4-adba-11aaf9f2ee71",
          "name": "ALOE BARBADENSIS MILLER LEAF [EMA HERBAL SUBSTANCE]",
          "stdName": "ALOE BARBADENSIS MILLER LEAF [EMA HERBAL SUBSTANCE]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b"
          ],
          "display_name": false
        },
        {
          "uuid": "2aedcf6d-35c3-464c-b1cc-7b51ee5acb55",
          "name": "ALOE CAPENSIS LEAF [EMA HERBAL SUBSTANCE]",
          "stdName": "ALOE CAPENSIS LEAF [EMA HERBAL SUBSTANCE]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b"
          ],
          "display_name": false
        },
        {
          "uuid": "0bdf0465-5ea4-4518-886d-cd094a55950a",
          "name": "ALOE EXTRACT",
          "stdName": "ALOE EXTRACT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3a34922c-ca5a-4b5a-92f0-96059b149ec8"
          ],
          "display_name": false
        },
        {
          "uuid": "d9e5046d-b2ad-4113-b237-08050b215ef8",
          "name": "ALOE FEROX MILLER LEAF [EMA HERBAL SUBSTANCE]",
          "stdName": "ALOE FEROX MILLER LEAF [EMA HERBAL SUBSTANCE]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b"
          ],
          "display_name": false
        },
        {
          "uuid": "16f9d9b1-6664-465c-b448-4f7ba1afe108",
          "name": "ALOE LEAF",
          "stdName": "ALOE LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f90ed1ac-107f-4cc8-b453-088f33f4815e"
          ],
          "display_name": false
        },
        {
          "uuid": "2f7fa854-5792-4c87-8f8b-dc397f772c90",
          "name": "ALOE LEAF INSPICCATED JUICE",
          "stdName": "ALOE LEAF INSPICCATED JUICE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7c09efce-8167-49ee-ac3c-c88362d3857b"
          ],
          "display_name": false
        },
        {
          "uuid": "7e125252-7e81-442b-aa04-f27645a93926",
          "name": "ALOE LEAF LATEX",
          "stdName": "ALOE LEAF LATEX",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f90ed1ac-107f-4cc8-b453-088f33f4815e"
          ],
          "display_name": false
        },
        {
          "uuid": "f7403e78-27ae-4d29-8948-9be5f8e4507c",
          "name": "ALOE SOCOTRINA",
          "stdName": "ALOE SOCOTRINA",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7c09efce-8167-49ee-ac3c-c88362d3857b",
            "9855b8c9-cae9-4c4d-ae9f-1cee47da11aa",
            "a988cd7c-b0ce-4483-b90b-34017ce55f17"
          ],
          "display_name": false
        },
        {
          "uuid": "68f95365-b0a1-4d72-afed-960c61672d3f",
          "name": "ALOE SOCOTRINA [HPUS]",
          "stdName": "ALOE SOCOTRINA [HPUS]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7c09efce-8167-49ee-ac3c-c88362d3857b",
            "a988cd7c-b0ce-4483-b90b-34017ce55f17"
          ],
          "display_name": false
        },
        {
          "uuid": "a5dd6a99-c5aa-403f-9b5b-4b9abe64fbbb",
          "name": "ALOE [FHFI]",
          "stdName": "ALOE [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08c8b5b-2b25-4baf-9c45-ffa3ee220da1"
          ],
          "display_name": false
        },
        {
          "uuid": "4e6de7ec-ef85-4012-9549-d2a423af4af1",
          "name": "ALOE [JAN]",
          "stdName": "ALOE [JAN]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "101510dc-7572-fcb1-aba7-3fbb0c41b750"
          ],
          "display_name": false
        },
        {
          "uuid": "db4114dc-421a-4cc2-9681-93079ae0b858",
          "name": "ALOE [MI]",
          "stdName": "ALOE [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "576472af-419a-4969-b2c8-71f6ba2d57dd"
          ],
          "display_name": false
        },
        {
          "uuid": "c7ef1b76-3db7-4967-9069-a53356584f85",
          "name": "ALOE [USP MONOGRAPH]",
          "stdName": "ALOE [USP MONOGRAPH]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "08a05c28-6bb8-497c-99d9-3c9d578e53b2"
          ],
          "display_name": false
        },
        {
          "uuid": "07d3fcd6-f6d5-4999-9af4-14c8613befbe",
          "name": "ALOE [VANDF]",
          "stdName": "ALOE [VANDF]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "293f149f-db68-4f1b-a741-381273364657"
          ],
          "display_name": false
        },
        {
          "uuid": "44422e51-f113-47a5-8dcc-5b389e547024",
          "name": "ALOE, EXTRACT",
          "stdName": "ALOE, EXTRACT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "75a382dd-496f-41fe-a0e4-2cd2245275ba"
          ],
          "display_name": false
        },
        {
          "uuid": "d790230d-4874-4055-80e5-4af9daf65070",
          "name": "ALOE, UNSPECIFIED",
          "stdName": "ALOE, UNSPECIFIED",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "30d1496d-dbec-4c38-9a1b-0a1ba634a2b5"
          ],
          "display_name": false
        },
        {
          "uuid": "eec5e11b-bd9d-4bac-93ca-c2a0ecffce25",
          "name": "ALOES",
          "stdName": "ALOES",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b",
            "c55767e7-822c-403f-a9b8-5a933a6cddd0",
            "20f7e758-fe77-400f-a8f0-df0facf65e36"
          ],
          "display_name": false
        },
        {
          "uuid": "03f5923b-32eb-413a-8aea-9bd30c4e1f49",
          "name": "ALOES [EMA HERBAL SUBSTANCE]",
          "stdName": "ALOES [EMA HERBAL SUBSTANCE]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b"
          ],
          "display_name": false
        },
        {
          "uuid": "5714a4ee-ba3c-43da-a15e-a352fbad790c",
          "name": "ALOES- [EMA HERBAL SUBSTANCE]",
          "stdName": "ALOES- [EMA HERBAL SUBSTANCE]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4c39239f-491d-40e0-9b6f-acd4ae406d9b"
          ],
          "display_name": false
        },
        {
          "uuid": "a7f732f1-5d87-495c-9723-24f215d1cea6",
          "name": "B2348 [LANGUAL]",
          "stdName": "B2348 [LANGUAL]",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "1d971f01-cc71-4b21-9563-932bddba4bb8"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "3c1ff4e0-c602-4bc9-b0e3-2d9c4bfda3c4",
          "citation": "USP/NF 26",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "f90ed1ac-107f-4cc8-b453-088f33f4815e",
          "citation": "USP/NF",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7c09efce-8167-49ee-ac3c-c88362d3857b",
          "citation": "HPUS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "75a382dd-496f-41fe-a0e4-2cd2245275ba",
          "citation": "EAFUS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c55767e7-822c-403f-a9b8-5a933a6cddd0",
          "citation": "MARTINDALE",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a988cd7c-b0ce-4483-b90b-34017ce55f17",
          "citation": "HPUS 2011",
          "doc_type": "HOMEOPATHIC PHARMACOPOEIA US",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "08a05c28-6bb8-497c-99d9-3c9d578e53b2",
          "citation": "USP 33",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d08c8b5b-2b25-4baf-9c45-ffa3ee220da1",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "576472af-419a-4969-b2c8-71f6ba2d57dd",
          "citation": "Merck",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "30d1496d-dbec-4c38-9a1b-0a1ba634a2b5",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3a34922c-ca5a-4b5a-92f0-96059b149ec8",
          "citation": "rxnorm",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1d971f01-cc71-4b21-9563-932bddba4bb8",
          "citation": "LANGUAL",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "293f149f-db68-4f1b-a741-381273364657",
          "citation": "NDF-RT",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4c39239f-491d-40e0-9b6f-acd4ae406d9b",
          "citation": "http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/herbal/medicines/herbal_med_000011.jsp&m",
          "url": "http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/herbal/medicines/herbal_med_000011.jsp&m",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "dfa99df8-2e7b-4f97-9d57-ddb80e818143",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390552000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8eda4af2-2243-4cbc-a78e-927a1be64370",
          "citation": "SRS import [V5VD430YW9]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=V5VD430YW9",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390552000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9855b8c9-cae9-4c4d-ae9f-1cee47da11aa",
          "citation": "ALOE SOCOTRINA [HPUS]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b4370f19-d19c-410a-9844-272a9d4bf993",
          "citation": "ALOE [USP]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "173b8432-9f63-4372-adf2-4543b9391ba8",
          "citation": "ALOE [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "0e8098e1-ee38-4c84-8bf6-012635462eca",
          "citation": "ALOE [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b0635687-bb33-44ce-a1af-8cc2c803e1fd",
          "citation": "ALOE [VANDF]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "20f7e758-fe77-400f-a8f0-df0facf65e36",
          "citation": "ALOES [EMA HERBAL SUBSTANCE]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "101510dc-7572-fcb1-aba7-3fbb0c41b750",
          "citation": "JAN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "05dc941e-3abf-a89e-07f8-67f40482e7c7",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "edce0ed3-560f-f514-f9a3-9e0122a2ea1a",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        }
      ],
      "mixture": {
        "uuid": "41e54471-6190-4161-b863-31b67dc999eb",
        "components": [
          {
            "uuid": "21130fc8-9fbf-4ca9-8e30-384767e864f5",
            "type": "MAY_BE_PRESENT_ONE_OF",
            "substance": {
              "uuid": "bae74f13-6965-4d74-81f3-e544542a602b",
              "refuuid": "65127ee0-6828-4d9c-b5de-2e752df51a22",
              "name": "ALOE VERA LEAF",
              "unii": "ZY81Z83H0X",
              "linking_id": "ZY81Z83H0X",
              "ref_pname": "ALOE VERA LEAF",
              "substance_class": "reference"
            },
            "references": []
          },
          {
            "uuid": "72cd3420-d4b5-4895-b952-c987538fd176",
            "type": "MAY_BE_PRESENT_ONE_OF",
            "substance": {
              "uuid": "26df4d75-150e-4017-b8b7-bdfdf156b4c2",
              "refuuid": "68dd53e3-4b1b-4849-b7a6-2931022aca6f",
              "name": "ALOE FEROX LEAF",
              "unii": "0D145J8EME",
              "linking_id": "0D145J8EME",
              "ref_pname": "ALOE FEROX LEAF",
              "substance_class": "reference"
            },
            "references": []
          }
        ],
        "references": [
          "f90ed1ac-107f-4cc8-b453-088f33f4815e",
          "8eda4af2-2243-4cbc-a78e-927a1be64370"
        ]
      },
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "78173142-8aa6-4487-b293-935aa058de79",
      "version": "7",
      "modifications": {
        "uuid": "290921ac-b8a5-4eed-b5f6-df3a0f266fee"
      },
      "unii": "V5VD430YW9"
    }
  ]
}