{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "e703c0d5-2086-49f4-a2d0-23c9f1bfe806",
          "code": "104-49-4",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=104-49-4",
          "code_system": "CAS",
          "references": [
            "156cfbb2-11e6-40c2-b98c-7bd9d1d3461a",
            "53adedc2-99b5-465c-866d-0c8fa253e732"
          ]
        },
        {
          "uuid": "7abf2345-4b3d-44ed-a74d-8bfb36915044",
          "code": "203-207-6",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.002.916",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "156cfbb2-11e6-40c2-b98c-7bd9d1d3461a"
          ]
        },
        {
          "uuid": "b0e5f787-4f3b-45f6-9488-d98b185e7a5d",
          "code": "61009",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/61009",
          "code_system": "PUBCHEM",
          "references": [
            "156cfbb2-11e6-40c2-b98c-7bd9d1d3461a"
          ]
        },
        {
          "uuid": "bc693341-b014-7b8f-779d-8b801209ca36",
          "code": "DTXSID3025883",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID3025883",
          "code_system": "EPA CompTox",
          "references": [
            "594643d3-a988-5907-7efa-9d5c8cbd0b95"
          ]
        },
        {
          "uuid": "3013be3c-7a07-40db-b0cf-773545a665c8",
          "code": "OKE64XZR2L",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "28b74feb-4ffb-b829-eae1-cb049c86b30e",
          "code": "94776",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=94776",
          "code_system": "NSC",
          "references": [
            "d0f193d9-3aa8-277c-b4be-d52607ac8a01"
          ]
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "8771f321-759c-4242-84b7-1a8db6899ea2",
          "name": "1,4-DIISOCYANATOBENZENE",
          "stdName": "1,4-DIISOCYANATOBENZENE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5131d43b-233d-4d97-9308-6d201c83900e"
          ],
          "display_name": true
        },
        {
          "uuid": "586ed406-8a49-48ce-94ba-cc802a745ad3",
          "name": "1,4-PHENYLENE DIISOCYANATE",
          "stdName": "1,4-PHENYLENE DIISOCYANATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "3af1cb1c-cfa4-4d55-960a-16cf87b5025b",
          "name": "1,4-PHENYLENEBIS(ISOCYANATE)",
          "stdName": "1,4-PHENYLENEBIS(ISOCYANATE)",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "8cac8629-1861-4872-a3a7-b232c309c117",
          "name": "BENZENE, 1,4-DIISOCYANATO-",
          "stdName": "BENZENE, 1,4-DIISOCYANATO-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "33400df0-2efe-4977-805c-27eb39ccf969",
          "name": "HYDROQUINONE, DIISOCYANATE",
          "stdName": "HYDROQUINONE, DIISOCYANATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "5c02757e-16ad-4dba-bd55-a048fbdc6809",
          "name": "ISOCYANIC ACID, P-PHENYLENE ESTER",
          "stdName": "ISOCYANIC ACID, P-PHENYLENE ESTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "0096705b-9a0e-4b5a-8066-9ec21ec78377",
          "name": "NSC-94776",
          "stdName": "NSC-94776",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "abe7c2ef-bab8-4893-8014-2562c33769e8"
          ],
          "display_name": false
        },
        {
          "uuid": "7bd2d653-46be-40ae-a0e0-65032877a71a",
          "name": "P-PHENYLENE DIISOCYANATE",
          "stdName": "P-PHENYLENE DIISOCYANATE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "ddccf814-0034-44b2-af64-c109c18998dd",
          "name": "P-PHENYLENE ISOCYANATE",
          "stdName": "P-PHENYLENE ISOCYANATE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        },
        {
          "uuid": "060e21d9-b15c-43df-b9f7-771c21d3d126",
          "name": "PPDI",
          "stdName": "PPDI",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0bbf3e61-71a6-4ed5-bdad-1267af1d554e"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "5131d43b-233d-4d97-9308-6d201c83900e",
          "citation": "CFSAN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "0bbf3e61-71a6-4ed5-bdad-1267af1d554e",
          "citation": "STN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "abe7c2ef-bab8-4893-8014-2562c33769e8",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "156cfbb2-11e6-40c2-b98c-7bd9d1d3461a",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493392183000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b5e0ba2b-2a6e-40fb-bd2c-cdab6231f0fb",
          "citation": "SRS import [OKE64XZR2L]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=OKE64XZR2L",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493392183000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "594643d3-a988-5907-7efa-9d5c8cbd0b95",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=104-49-4",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "53adedc2-99b5-465c-866d-0c8fa253e732",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "d0f193d9-3aa8-277c-b4be-d52607ac8a01",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "9c8ea0fb-ed1f-4fd3-8149-6d1abe6ad971",
          "id": "9c8ea0fb-ed1f-4fd3-8149-6d1abe6ad971",
          "molfile": "\n  Marvin  01132108082D          \n\n 12 12  0  0  0  0            999 V2000\n    0.0000   -0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7112   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4225   -1.6557    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1337   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8449   -1.6501    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5562   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5562   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8449    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1337   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.2731   -0.0114    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    4.9787   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.6899   -0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  2  0  0  0  0\n  3  2  2  0  0  0  0\n  3  4  1  0  0  0  0\n  4  5  1  0  0  0  0\n  4  9  2  0  0  0  0\n  5  6  2  0  0  0  0\n  6  7  1  0  0  0  0\n  8  7  2  0  0  0  0\n 10  7  1  0  0  0  0\n  9  8  1  0  0  0  0\n 10 11  2  0  0  0  0\n 11 12  2  0  0  0  0\nM  END",
          "smiles": "c1cc(ccc1N=C=O)N=C=O",
          "formula": "C8H4N2O2",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "78b388ab-c0b7-4ff6-bfb5-de968d118e1b"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "160.1299",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "5d9047ef-4397-4ac1-94c2-aa45fc2ca0eb",
      "version": "4",
      "structure": {
        "id": "42fd5ad9-bfa9-4d2f-85c8-36843cf5481b",
        "molfile": "\n  Marvin  01132103322D          \n\n 12 12  0  0  0  0            999 V2000\n    1.4225   -1.6557    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7112   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.2731   -0.0114    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    4.9787   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.6899   -0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1337   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8449   -1.6501    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1337   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5562   -1.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8449    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5562   -0.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  2  0  0  0  0\n  1  7  1  0  0  0  0\n  2  3  2  0  0  0  0\n  4  5  2  0  0  0  0\n  4 12  1  0  0  0  0\n  5  6  2  0  0  0  0\n  7  8  2  0  0  0  0\n  7  9  1  0  0  0  0\n  8 10  1  0  0  0  0\n  9 11  2  0  0  0  0\n 10 12  2  0  0  0  0\n 11 12  1  0  0  0  0\nM  END",
        "smiles": "c1cc(ccc1N=C=O)N=C=O",
        "formula": "C8H4N2O2",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "160.1299",
        "optical_activity": "NONE",
        "references": [
          "b5e0ba2b-2a6e-40fb-bd2c-cdab6231f0fb",
          "5131d43b-233d-4d97-9308-6d201c83900e"
        ],
        "stereo_centers": 0
      },
      "unii": "OKE64XZR2L"
    }
  ]
}