{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "e1ecd643-536a-4e6d-ac7d-a414aabadd69",
          "code": "MEQ84W5J4Q",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "f52b56ed-3747-dc3a-bc77-56e661df5455",
          "code": "100000076856",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "f4c5197b-f0a4-f732-dbc3-5d5029e40e35"
          ]
        }
      ],
      "substance_class": "protein",
      "references": [
        {
          "uuid": "e1817656-5883-4350-9a22-f34fa931f3f1",
          "citation": "https://www.sciencedirect.com/science/article/pii/S000862152100001X",
          "url": "https://www.sciencedirect.com/science/article/pii/S000862152100001X",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "71db9c18-c65c-4a5e-b051-c8ec91055220",
          "citation": "P126",
          "url": "https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/pl126.pdf",
          "doc_type": "INN_LIST",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "87b488b0-1c8d-4ca9-a167-937d56b666fc",
          "citation": "USAN January 27, 2021",
          "doc_type": "USANCOUN",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "5b4f98f1-395f-447e-b3cd-65e8e10ac872",
          "citation": "P16278",
          "url": "https://www.uniprot.org/uniprot/P16278",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "76e45bd3-6ecf-40e7-a262-8011d1416ce8",
          "citation": "USAN January 27, 2021",
          "doc_type": "USANCOUN",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "5fa9a0e1-e180-4b7f-91df-ea4848300c44",
          "citation": "Rabinowitz, Zachary M., and Lina Cui. \"Detecting cellular senescence in vivo: Imagining imaging better.\" Aging and Cancer (2023).",
          "url": "https://onlinelibrary.wiley.com/doi/full/10.1002/aac2.12067",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "dfade9ba-c9b8-4e1f-a126-66025b8e3cb3",
          "citation": "Rabinowitz, Zachary M., and Lina Cui. \"Detecting cellular senescence in vivo: Imagining imaging better.\" Aging and Cancer (2023).",
          "url": "https://onlinelibrary.wiley.com/doi/full/10.1002/aac2.12067",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f4c5197b-f0a4-f732-dbc3-5d5029e40e35",
          "citation": "SMS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "e4230b8d-e9e4-451b-8d3f-75c8ab356c32",
      "version": "11",
      "unii": "MEQ84W5J4Q",
      "relationships": [
        {
          "uuid": "4fd49731-0fba-4fbf-87c1-8b63341bc38c",
          "amount": {
            "uuid": "2a24d952-cd92-4fd7-92aa-eb901fe8c7e2"
          },
          "type": "VECTOR->EXPRESSED PROTEIN",
          "related_substance": {
            "uuid": "5afda71d-90e8-4616-b6e4-caeeeb535fde",
            "refuuid": "e17a47ee-a6a7-4d7d-8b6d-98d6452d3710",
            "name": "Seglebegagene Dasniparvovec",
            "unii": "EXB5VWG5TW",
            "linking_id": "EXB5VWG5TW",
            "ref_pname": "Seglebegagene Dasniparvovec"
          }
        },
        {
          "uuid": "77b6712e-bb25-410e-9156-d10812a48b35",
          "amount": {
            "uuid": "e16dce73-0806-4cbc-9b93-6cd77f58f9d6"
          },
          "type": "LIGAND->TARGET",
          "references": [
            "e1817656-5883-4350-9a22-f34fa931f3f1"
          ],
          "related_substance": {
            "uuid": "37cf93ea-df66-4b11-83cd-83ea609ff7f9",
            "refuuid": "7019c1ad-0ad5-4491-a9da-93b74c1bef84",
            "name": "GAXILOSE",
            "unii": "A571S2B3JE",
            "linking_id": "A571S2B3JE",
            "ref_pname": "GAXILOSE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "59075360-c733-4ab2-84eb-f0e4867c28ee",
          "amount": {
            "uuid": "d4e6e8f9-aeb0-4f55-b632-a74210bd7a83"
          },
          "type": "VECTOR->EXPRESSED PROTEIN",
          "references": [
            "71db9c18-c65c-4a5e-b051-c8ec91055220"
          ],
          "related_substance": {
            "uuid": "baab158e-7047-40ed-91cc-90bffce8ef2a",
            "refuuid": "ac1b6dc7-036f-41b0-b164-7eda84b033d6",
            "name": "LIXMABEGAGENE RELDUPARVOVEC",
            "unii": "8G4FJ7F8EY",
            "linking_id": "8G4FJ7F8EY",
            "ref_pname": "LIXMABEGAGENE RELDUPARVOVEC",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "adc9ead9-de89-46ab-ab8f-03a8a1ba3310",
          "amount": {
            "uuid": "7d65aa4d-b72f-42b3-9ac9-d3fd597ff86c"
          },
          "type": "PARENT->DAUGHTER",
          "references": [
            "87b488b0-1c8d-4ca9-a167-937d56b666fc"
          ],
          "related_substance": {
            "uuid": "b624592b-31ac-4b52-abfc-67dc22344b11",
            "refuuid": "54c3fec9-9a95-4bbc-9083-7398faf47e3b",
            "name": "BOMTABEGAGENE BAVOPARVOVEC EXPRESSED BETA-GALACTOSIDASE PREPROTEIN",
            "unii": "GR87RLW7UV",
            "linking_id": "GR87RLW7UV",
            "ref_pname": "BOMTABEGAGENE BAVOPARVOVEC EXPRESSED BETA-GALACTOSIDASE PREPROTEIN",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "2b2ceb0d-8242-4640-938e-e08dec65baf0",
          "amount": {
            "uuid": "775ab463-f6b5-4f34-b2ad-763e69f7d86c"
          },
          "type": "VECTOR->EXPRESSED PROTEIN",
          "references": [
            "76e45bd3-6ecf-40e7-a262-8011d1416ce8"
          ],
          "related_substance": {
            "uuid": "972822f6-46ee-4156-adc8-cf9b8b96671b",
            "refuuid": "e076c7b9-d83d-4a7c-96a8-8080c2153966",
            "name": "BOMTABEGAGENE BAVOPARVOVEC",
            "unii": "ZMG9G56THB",
            "linking_id": "ZMG9G56THB",
            "ref_pname": "BOMTABEGAGENE BAVOPARVOVEC"
          }
        },
        {
          "uuid": "8591b9d2-57dc-4842-bb02-08fa632bb368",
          "amount": {
            "uuid": "f9b0e03c-5290-415d-a518-cfe25bd948c8"
          },
          "comments": "Used as a in-vivo marker for cell senescence. ",
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "5fa9a0e1-e180-4b7f-91df-ea4848300c44"
          ],
          "related_substance": {
            "uuid": "af9b8a37-514c-44cf-9764-03e92f845571",
            "refuuid": "f76e3e9a-21e6-4e77-91c9-996596a17b73",
            "name": "2-Fluoropyridin-3-yl β-D-galactopyranoside F-18",
            "unii": "Z63S8T4TGE",
            "linking_id": "Z63S8T4TGE",
            "ref_pname": "2-Fluoropyridin-3-yl β-D-galactopyranoside F-18",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "a76b5096-6b70-4a9f-9cb1-09f484688580",
          "amount": {
            "uuid": "88ea6489-e6fc-4b39-9a01-05c44371f4f1"
          },
          "type": "SUBSTRATE->ENZYME",
          "references": [
            "dfade9ba-c9b8-4e1f-a126-66025b8e3cb3"
          ],
          "related_substance": {
            "uuid": "b7dbfbff-e1d8-4bcf-a778-96a2e0c819bf",
            "refuuid": "58ba3437-89a3-4c2a-a7fa-7d9b3a7b1f09",
            "name": "2-Fluoropyridin-3-yl β-D-galactopyranoside",
            "unii": "3XEN3WZG6L",
            "linking_id": "3XEN3WZG6L",
            "ref_pname": "2-Fluoropyridin-3-yl β-D-galactopyranoside",
            "substance_class": "reference"
          }
        }
      ],
      "names": [
        {
          "uuid": "1895ee96-7568-4bbe-bbe3-a89fcf49ddeb",
          "name": "ACID BETA-GALACTOSIDASE",
          "stdName": "ACID BETA-GALACTOSIDASE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
          ],
          "display_name": false
        },
        {
          "uuid": "6bbf7186-7be1-4b8e-9032-5db235233f46",
          "name": "BETA-GALACTOSIDASE",
          "stdName": "BETA-GALACTOSIDASE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
          ],
          "display_name": true
        },
        {
          "uuid": "c8a302c8-8185-464b-a351-a75ed1fb4a0a",
          "name": "ELASTIN RECEPTOR 1",
          "stdName": "ELASTIN RECEPTOR 1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
          ],
          "display_name": false
        },
        {
          "uuid": "6bb74a40-3f31-4167-af8c-52b580b81443",
          "name": "GLB1",
          "stdName": "GLB1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
          ],
          "display_name": false
        },
        {
          "uuid": "8c5a773f-0f9d-4c0e-9951-475f4e26d8f8",
          "name": "LACTASE (HUMAN)",
          "stdName": "LACTASE (HUMAN)",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
          ],
          "display_name": false
        }
      ],
      "protein": {
        "uuid": "5c368c14-8a56-4230-b667-fcce23a09e99",
        "glycosylation": {
          "uuid": "542d0d82-c6a4-452e-a6e8-1bcd42ab80a2",
          "n_glycosylation_sites": [
            {
              "residue_index": 219,
              "subunit_index": 1
            },
            {
              "residue_index": 436,
              "subunit_index": 1
            },
            {
              "residue_index": 470,
              "subunit_index": 1
            },
            {
              "residue_index": 514,
              "subunit_index": 1
            },
            {
              "residue_index": 517,
              "subunit_index": 1
            },
            {
              "residue_index": 527,
              "subunit_index": 1
            },
            {
              "residue_index": 219,
              "subunit_index": 2
            },
            {
              "residue_index": 436,
              "subunit_index": 2
            },
            {
              "residue_index": 470,
              "subunit_index": 2
            },
            {
              "residue_index": 514,
              "subunit_index": 2
            },
            {
              "residue_index": 517,
              "subunit_index": 2
            },
            {
              "residue_index": 527,
              "subunit_index": 2
            }
          ]
        },
        "subunits": [
          {
            "uuid": "578508fa-e371-41e4-ba24-2283fc6f7514",
            "sequence": "QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV",
            "subunit_index": 1
          },
          {
            "uuid": "f9de672c-72f3-4ac2-b3a9-34dd58a4d2e6",
            "sequence": "QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV",
            "subunit_index": 2
          }
        ],
        "references": [
          "5b4f98f1-395f-447e-b3cd-65e8e10ac872"
        ],
        "disulfide_links": [
          {
            "sites": [
              {
                "residue_index": 598,
                "subunit_index": 2
              },
              {
                "residue_index": 606,
                "subunit_index": 2
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 167,
                "subunit_index": 2
              },
              {
                "residue_index": 202,
                "subunit_index": 2
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 598,
                "subunit_index": 1
              },
              {
                "residue_index": 606,
                "subunit_index": 1
              }
            ]
          },
          {
            "sites": [
              {
                "residue_index": 167,
                "subunit_index": 1
              },
              {
                "residue_index": 202,
                "subunit_index": 1
              }
            ]
          }
        ],
        "protein_sub_type": "",
        "protein_type": "ENZYME",
        "sequence_origin": "HUMAN",
        "sequence_type": "COMPLETE"
      },
      "properties": [
        {
          "uuid": "9e615052-0221-4605-94fe-57921fbc0635",
          "name": "MOL_WEIGHT:NUMBER(CALCULATED)",
          "type": "amount",
          "value": {
            "uuid": "66bfeac2-55b2-4c89-b196-4f3fa816ec5c",
            "type": "ESTIMATED",
            "average": 146062.366,
            "units": "Da"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        },
        {
          "uuid": "636c8a5e-ab0f-4a04-8fda-f04035571c27",
          "name": "Molecular Formula",
          "value": {
            "uuid": "4164f06d-9776-45da-9057-365a7e409d65",
            "type": "ESTIMATED",
            "non_numeric_value": "C6692H10084O1892N1720S36"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "4c478d97-80e6-4044-b62e-0d4f84c13462"
      }
    }
  ]
}