{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "1574e54e-de9e-4da5-b9a9-47c66ac09d79",
          "code": "C71838",
          "type": "PRIMARY",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C71838",
          "code_system": "NCI_THESAURUS",
          "references": [
            "ac1dbdd9-48ec-4211-9e77-05581c63ecbb"
          ]
        },
        {
          "uuid": "3011842c-6ae8-464e-bb89-c2b6dfa91415",
          "code": "68650-46-4",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=68650-46-4",
          "code_system": "CAS",
          "references": [
            "ac1dbdd9-48ec-4211-9e77-05581c63ecbb",
            "33d12baf-046d-4823-8232-579d7d3593fa"
          ]
        },
        {
          "uuid": "222b85dc-a8a2-8053-c168-c80e6301dabd",
          "code": "DTXSID20100798",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID20100798",
          "code_system": "EPA CompTox",
          "references": [
            "c0d1ec6e-d5c6-f06a-5af1-4cdf09a37fe8"
          ]
        },
        {
          "uuid": "97e1d959-5894-401a-b60c-06adb8fc8300",
          "code": "236531",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/236531/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "7c03f944-7186-86df-c98b-b131989e254e"
          ]
        },
        {
          "uuid": "bbe28969-44f3-d3a5-23bc-cfafcd2b1b66",
          "code": "C79688",
          "comments": "Natural Product[C66892]|Plant-based Natural Product[C106104]|Plant Part[C79611]|Plant Oil",
          "type": "CONCEPT",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C79688",
          "code_system": "NCI_THESAURUS",
          "references": [
            "c22096f0-5117-132d-aef5-0f786a7976c5"
          ]
        },
        {
          "uuid": "95aeb48d-4a39-a954-46b6-fa81e005dcbf",
          "code": "2108820",
          "type": "ALTERNATIVE",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/2108820/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "c22096f0-5117-132d-aef5-0f786a7976c5"
          ]
        },
        {
          "uuid": "9d717b4e-1e38-30f8-0eab-ed8d1be104bc",
          "code": "364 (Number of products:112)",
          "comments": "Dietary Supplement Label Database|Botanical|Buchu",
          "type": "PRIMARY",
          "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=364&item=Buchu",
          "code_system": "DSLD",
          "references": [
            "c22096f0-5117-132d-aef5-0f786a7976c5"
          ]
        },
        {
          "uuid": "c645b29b-8f9a-44e1-9da3-4e8bad5d05b3",
          "code": "KOS935A04V",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "44a9a949-42b0-c1cb-9837-61907c944fdd",
          "code": "KOS935A04V",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=KOS935A04V",
          "code_system": "DAILYMED",
          "references": [
            "f949e9c6-c33d-21ed-62cf-8e076908eefd"
          ]
        }
      ],
      "substance_class": "structurallyDiverse",
      "names": [
        {
          "uuid": "128efc6a-8d5d-4aab-81dc-aefa7fc822b0",
          "name": "AGATHOSMA BETULINA LEAF OIL",
          "stdName": "AGATHOSMA BETULINA LEAF OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f595c4a5-a947-4ccc-bf21-6fbd5629c81a"
          ],
          "display_name": true
        },
        {
          "uuid": "ce3ead6a-81a5-4428-8dc6-3e2e903af913",
          "name": "AGATHOSMA BETULINA LEAF VOLATILE OIL",
          "stdName": "AGATHOSMA BETULINA LEAF VOLATILE OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "18391674-22ea-41e7-9fdf-6828fabc9e8d"
          ],
          "display_name": false
        },
        {
          "uuid": "49421757-9e32-65ed-722e-b14726db46bc",
          "name": "Agathosma betulina oil [WHO-DD]",
          "stdName": "AGATHOSMA BETULINA OIL [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "24a22165-0a69-7c78-34b1-1ef8282876b4"
          ],
          "display_name": false
        },
        {
          "uuid": "9a2f5a15-f60e-4df3-8536-1a5f4ca54c57",
          "name": "BAROSMA BETULINA LEAF OIL",
          "stdName": "BAROSMA BETULINA LEAF OIL",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": true,
          "references": [
            "9f4beed1-1c2a-4265-946e-202089c1f942",
            "890a56bf-0c21-4da6-8e7e-b7375fc6695d",
            "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
            "fe0389bf-ee4b-4c14-99e7-13178b5b585a",
            "eba47879-013c-4bab-adc1-cc29d50e27ab"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "e21cc0b7-b763-4297-814f-cde3e3d631f1",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "a9feea48-9ef6-4950-ac2e-e304d4cf9f1e",
          "name": "BAROSMA ORBICULARIS LEAF OIL",
          "stdName": "BAROSMA ORBICULARIS LEAF OIL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
            "fe0389bf-ee4b-4c14-99e7-13178b5b585a"
          ],
          "display_name": false
        },
        {
          "uuid": "c74239e1-5fcb-4874-bd41-5c4ede23f701",
          "name": "BUCCO BETULINA LEAF OIL",
          "stdName": "BUCCO BETULINA LEAF OIL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
            "fe0389bf-ee4b-4c14-99e7-13178b5b585a"
          ],
          "display_name": false
        },
        {
          "uuid": "4f45e9b3-da0f-40e7-a3d7-bb93ee62e023",
          "name": "BUCCU LEAF OIL",
          "stdName": "BUCCU LEAF OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e82819de-9e27-4b15-b21c-0ae7643fb313",
            "39b04358-830c-45ad-a50c-5f678bbbad53"
          ],
          "display_name": false
        },
        {
          "uuid": "28876a39-0eed-a910-4a74-47029bbde300",
          "name": "BUCHU",
          "stdName": "BUCHU",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7c03f944-7186-86df-c98b-b131989e254e"
          ],
          "display_name": false
        },
        {
          "uuid": "47798293-a061-447d-bbe9-3e28e9f7efe4",
          "name": "BUCHU LEAF OIL",
          "stdName": "BUCHU LEAF OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f395a8e3-b669-4b43-bf32-1385277a5b55",
            "e392e89a-df84-488a-89e7-60cb5af72673"
          ],
          "display_name": false
        },
        {
          "uuid": "03478266-177e-4e66-b6d3-ef99f1426f30",
          "name": "BUCHU LEAVES OIL [FHFI]",
          "stdName": "BUCHU LEAVES OIL [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "2c7467df-f50b-4656-9a40-e8466e8df48d",
            "9ba27844-7a85-4d68-9044-14d9f2a1476c"
          ],
          "display_name": false
        },
        {
          "uuid": "49317e1e-b161-42e6-b525-22c28befc9fa",
          "name": "BUCHU OIL",
          "stdName": "BUCHU OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e82819de-9e27-4b15-b21c-0ae7643fb313",
            "39b04358-830c-45ad-a50c-5f678bbbad53"
          ],
          "display_name": false
        },
        {
          "uuid": "2dc5fdb7-ab9b-4567-9226-8d08e4c58d47",
          "name": "HARTOGIA BETULINA LEAF OIL",
          "stdName": "HARTOGIA BETULINA LEAF OIL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
            "fe0389bf-ee4b-4c14-99e7-13178b5b585a"
          ],
          "display_name": false
        },
        {
          "uuid": "d97f533b-6f48-439d-a3af-0ce0c5151263",
          "name": "PARAPETALIFERA BETULINA LEAF OIL",
          "stdName": "PARAPETALIFERA BETULINA LEAF OIL",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
            "fe0389bf-ee4b-4c14-99e7-13178b5b585a"
          ],
          "display_name": false
        },
        {
          "uuid": "5e79cd9a-da06-48df-b656-70189db15c6f",
          "name": "ROUND LEAF BUCHU LEAF OIL",
          "stdName": "ROUND LEAF BUCHU LEAF OIL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "6f0118ae-df2a-4ace-970f-084077263f68"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "f595c4a5-a947-4ccc-bf21-6fbd5629c81a",
          "citation": "ITIS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "6f0118ae-df2a-4ace-970f-084077263f68",
          "citation": "Wikipedia",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "2c7467df-f50b-4656-9a40-e8466e8df48d",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9ba27844-7a85-4d68-9044-14d9f2a1476c",
          "citation": "HANDBOOK OF FLAVOR INGREDIENTS",
          "doc_type": "HANDBOOK OF FLAVOR INGREDIENTS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "18391674-22ea-41e7-9fdf-6828fabc9e8d",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "eba47879-013c-4bab-adc1-cc29d50e27ab",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "890a56bf-0c21-4da6-8e7e-b7375fc6695d",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "f395a8e3-b669-4b43-bf32-1385277a5b55",
          "citation": "DMF",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e392e89a-df84-488a-89e7-60cb5af72673",
          "citation": "DMF",
          "doc_type": "DMF",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e82819de-9e27-4b15-b21c-0ae7643fb313",
          "citation": "SCIFINDER",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "39b04358-830c-45ad-a50c-5f678bbbad53",
          "citation": "STN (SCIFINDER)",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "49d4edb0-1dfa-42c0-8e4d-b8077377936d",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "87fd79c4-dc6f-4499-9488-cbe7cf3eb0e5",
          "citation": "WHO DRUG DICTIONARY",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ba7cfed2-8722-41f7-9d41-d2ef18c85848",
          "citation": "MPNS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fe0389bf-ee4b-4c14-99e7-13178b5b585a",
          "citation": "KEW GARDENS (WCPS)",
          "doc_type": "KEW GARDENS (WCPS)",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ac1dbdd9-48ec-4211-9e77-05581c63ecbb",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391316000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7b1095be-b3f9-4201-a5b0-8b7c23f0651b",
          "citation": "AN OVERVIEW OF THE EFFECTS OF TOBACCO INGREDIENTS ON SMOKE CHEMISTRY AND TOXICITY; FOOD AND CHEMICAL TOXICOLOGY; BAKER, RR; 42(SUPPL):53-83, 2004",
          "url": "http://www.sciencedirect.com/science/article/pii/S0278691504000043",
          "doc_type": "JOURNAL ARTICLE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8e379579-d0ed-4b8f-a7de-bf6c6ee807c4",
          "citation": "SRS import [KOS935A04V]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=KOS935A04V",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391316000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "2c05055b-3cc6-456f-aa96-a994baec4220",
          "citation": "Catalog of Life 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9f4beed1-1c2a-4265-946e-202089c1f942",
          "citation": "BAROSMA BETULINA LEAF OIL [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "c0d1ec6e-d5c6-f06a-5af1-4cdf09a37fe8",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=68650-46-4",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "7c03f944-7186-86df-c98b-b131989e254e",
          "citation": "RXNORM",
          "doc_type": "NLM",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "c22096f0-5117-132d-aef5-0f786a7976c5",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "33d12baf-046d-4823-8232-579d7d3593fa",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "f949e9c6-c33d-21ed-62cf-8e076908eefd",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "24a22165-0a69-7c78-34b1-1ef8282876b4",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "02e81391-0ce6-44a3-8617-f8a53e08ff84",
      "version": "10",
      "structurally_diverse": {
        "uuid": "45075f67-4fca-4091-a963-7ed2d4bd0dbd",
        "fraction_name": "volatile oil",
        "parent_substance": {
          "uuid": "acfe199e-22b2-4d95-a2cf-45eb728614a2",
          "refuuid": "b40ba293-2775-4ccb-834d-b775d551c213",
          "name": "AGATHOSMA BETULINA WHOLE",
          "unii": "9PD9T4W96S",
          "linking_id": "9PD9T4W96S",
          "ref_pname": "AGATHOSMA BETULINA WHOLE",
          "substance_class": "reference"
        },
        "part": [
          "leaf"
        ],
        "references": [
          "2c05055b-3cc6-456f-aa96-a994baec4220",
          "8e379579-d0ed-4b8f-a7de-bf6c6ee807c4"
        ],
        "source_material_class": "ORGANISM",
        "source_material_type": "PLANT"
      },
      "modifications": {
        "uuid": "7dea8bb1-6be5-48a2-84a4-308de98a5743"
      },
      "unii": "KOS935A04V"
    }
  ]
}