{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "191f5e2e-754c-4a46-a119-8ead960513f9",
          "code": "ISOQUINOLINE",
          "comments": "JECFA|FUNCTIONAL CLASSIFICATION|Flavouring Agent",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=4927",
          "code_system": "JECFA EVALUATION",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "03e087b4-8a27-42b0-a448-85a3bf12ee74",
          "code": "119-65-3",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=119-65-3",
          "code_system": "CAS",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf",
            "e2850b37-7aae-43f9-a0ce-94f641479dc6"
          ]
        },
        {
          "uuid": "619b9cf2-4387-4568-bd9f-3145bc1af949",
          "code": "C039109",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67039109",
          "code_system": "MESH",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "d5de9dfe-db51-4879-8d97-41dd71474642",
          "code": "21 CFR 172.515",
          "comments": "PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION|Subpart F--Flavoring Agents and Related Substances|Sec. 172.515 Synthetic flavoring substances and adjuvants.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=172.515",
          "code_system": "CFR",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "cdc9e582-2966-4730-a16a-118febbcd7c1",
          "code": "ISOQUINOLINE",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Isoquinoline",
          "code_system": "WIKIPEDIA",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "597b47cd-9e47-44fd-8cfc-93f5710145e2",
          "code": "204-341-8",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.003.947",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "8a17a6cd-26ef-4fc4-90f3-8e3e9558429f",
          "code": "m6538",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m6538?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "1eb665e1-cb6e-48d6-8b76-2bb3eed80106",
          "code": "8405",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/8405",
          "code_system": "PUBCHEM",
          "references": [
            "b5170071-d480-4e58-a57f-3d21cb07fcaf"
          ]
        },
        {
          "uuid": "dd3b46f8-cd05-f00b-1be1-3b0bedd05368",
          "code": "DTXSID2047644",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID2047644",
          "code_system": "EPA CompTox",
          "references": [
            "e811d936-fdb9-e6ce-211b-9371fb2c2759"
          ]
        },
        {
          "uuid": "9337f611-d103-d352-17a5-240ed2d4b204",
          "code": "DB04329",
          "type": "PRIMARY",
          "url": "https://go.drugbank.com/drugs/DB04329",
          "code_system": "DRUG BANK",
          "references": [
            "e74230d3-9584-7632-7286-22b42522656a"
          ]
        },
        {
          "uuid": "e41793c7-b34a-492b-ab07-1db348f9c17f",
          "code": "JGX76Y85M6",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "0f46d5d1-c137-6d64-0148-3b657a60117f",
          "code": "16092",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:16092",
          "code_system": "CHEBI",
          "references": [
            "e74230d3-9584-7632-7286-22b42522656a"
          ]
        },
        {
          "uuid": "24541afe-2a03-f45e-00b8-e3fd4492485d",
          "code": "3395",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=3395",
          "code_system": "NSC",
          "references": [
            "29323310-c96c-e450-52c1-f57fbe220f3a"
          ]
        },
        {
          "uuid": "0c5b918f-6166-6279-8bfa-f696d2ef544e",
          "code": "1187",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/1187/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "d46cab2c-7ee7-af34-5157-943989e135cd"
          ]
        },
        {
          "uuid": "6f24160a-edee-d554-f2fb-eb27de81737f",
          "code": "300000053418",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "7cfe0757-15ba-40eb-e2bc-91a033984b5c"
          ]
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "f9e3a374-683d-44d1-ad2f-e5681a484077",
          "name": "2-BENZAZINE",
          "stdName": "2-BENZAZINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e1673ccf-41a9-4277-aaf0-2c45397923f9",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590"
          ],
          "display_name": false
        },
        {
          "uuid": "9d172dcc-8b2c-453f-9abb-c2f0de2b579e",
          "name": "BETA-QUINOLINE",
          "stdName": "BETA-QUINOLINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e1673ccf-41a9-4277-aaf0-2c45397923f9",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590"
          ],
          "display_name": false
        },
        {
          "uuid": "44e87676-070d-4ca3-9e11-5cfdcdb693f3",
          "name": "FEMA NO. 2978",
          "stdName": "FEMA NO. 2978",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "16084498-f219-4ce8-8ed0-fa8614606013"
          ],
          "display_name": false
        },
        {
          "uuid": "1c67b0e4-4a91-461e-8f99-1806315d0211",
          "name": "ISOQUINOLINE",
          "stdName": "ISOQUINOLINE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9b76b6c7-2e8b-4840-a910-272e9502cf10",
            "e1673ccf-41a9-4277-aaf0-2c45397923f9",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590",
            "b8e8416d-e7fa-48c1-bee1-fe137ba0ef42",
            "b4558669-5193-4350-b721-99967a38fda6",
            "68e71f1d-008c-4080-9a2c-7f8967b0f459"
          ],
          "display_name": true
        },
        {
          "uuid": "57e2da62-2b02-4562-8a75-aeba74707d8a",
          "name": "ISOQUINOLINE [FHFI]",
          "stdName": "ISOQUINOLINE [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e1673ccf-41a9-4277-aaf0-2c45397923f9",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590"
          ],
          "display_name": false
        },
        {
          "uuid": "d8b99818-b93f-43bc-ad73-b132e3614a47",
          "name": "ISOQUINOLINE [MI]",
          "stdName": "ISOQUINOLINE [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9b76b6c7-2e8b-4840-a910-272e9502cf10",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590"
          ],
          "display_name": false
        },
        {
          "uuid": "5ac90461-2c81-4e47-be9f-9c1426f65472",
          "name": "LEUCOLINE",
          "stdName": "LEUCOLINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "e1673ccf-41a9-4277-aaf0-2c45397923f9",
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590"
          ],
          "display_name": false
        },
        {
          "uuid": "2ff8b733-7f6e-428c-ac7d-07660d8b857c",
          "name": "NSC-3395",
          "stdName": "NSC-3395",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3273247d-7f22-48b9-aa3c-5f29d2ac0590",
            "b5fe4be7-c55f-4348-8f6b-8b53ba8b5896"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "b4558669-5193-4350-b721-99967a38fda6",
          "citation": "EAFUS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "16084498-f219-4ce8-8ed0-fa8614606013",
          "citation": "CHEMID 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9b76b6c7-2e8b-4840-a910-272e9502cf10",
          "citation": "MERCK INDEX",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3273247d-7f22-48b9-aa3c-5f29d2ac0590",
          "citation": "MERCK INDEX",
          "doc_type": "MERCK INDEX",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e1673ccf-41a9-4277-aaf0-2c45397923f9",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b5fe4be7-c55f-4348-8f6b-8b53ba8b5896",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b5170071-d480-4e58-a57f-3d21cb07fcaf",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390522000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "72547098-4b09-4921-81bd-4a5aecc89609",
          "citation": "SRS import [JGX76Y85M6]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=JGX76Y85M6",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390522000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "68e71f1d-008c-4080-9a2c-7f8967b0f459",
          "citation": "ISOQUINOLINE [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b8e8416d-e7fa-48c1-bee1-fe137ba0ef42",
          "citation": "ISOQUINOLINE [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "e811d936-fdb9-e6ce-211b-9371fb2c2759",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=119-65-3",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "e74230d3-9584-7632-7286-22b42522656a",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "e2850b37-7aae-43f9-a0ce-94f641479dc6",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "29323310-c96c-e450-52c1-f57fbe220f3a",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "d46cab2c-7ee7-af34-5157-943989e135cd",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        },
        {
          "uuid": "7cfe0757-15ba-40eb-e2bc-91a033984b5c",
          "citation": "SMS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "6fa51c99-2349-44df-bf20-d45e432e3182",
          "id": "6fa51c99-2349-44df-bf20-d45e432e3182",
          "molfile": "\n  Marvin  01132105482D          \n\n 10 11  0  0  0  0            999 V2000\n    0.7086    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -0.4138    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -1.2413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7086   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7086   -2.4825    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4223   -2.8963    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1360   -2.4825    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1360   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4223   -1.2413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4223   -0.4138    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  1 10  2  0  0  0  0\n  2  3  2  0  0  0  0\n  3  4  1  0  0  0  0\n  4  5  1  0  0  0  0\n  9  4  2  0  0  0  0\n  5  6  2  0  0  0  0\n  7  6  1  0  0  0  0\n  8  7  2  0  0  0  0\n  9  8  1  0  0  0  0\n 10  9  1  0  0  0  0\nM  END",
          "smiles": "c1ccc2cnccc2c1",
          "formula": "C9H7N",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "53f2c332-79b8-4c9c-b510-872b088c3bc5"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "129.1589",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "692dd850-276f-4609-8ffe-7dcce0c2e2f7",
      "version": "10",
      "structure": {
        "id": "542f6d48-827e-44f5-83c5-0228bebb96e9",
        "molfile": "\n  Marvin  01132104232D          \n\n 10 11  0  0  0  0            999 V2000\n    1.4223   -2.8963    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7086   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4223   -1.2413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7086   -2.4825    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1360   -2.4825    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1360   -1.6551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4223   -0.4138    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -1.2413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -0.4138    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7086    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  2  4  2  0  0  0  0\n  3  6  2  0  0  0  0\n  4  1  1  0  0  0  0\n  5  1  2  0  0  0  0\n  6  5  1  0  0  0  0\n  7  3  1  0  0  0  0\n  8  2  1  0  0  0  0\n  9  8  2  0  0  0  0\n 10  7  2  0  0  0  0\n  3  2  1  0  0  0  0\n 10  9  1  0  0  0  0\nM  END",
        "smiles": "c1ccc2cnccc2c1",
        "formula": "C9H7N",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "129.1589",
        "optical_activity": "NONE",
        "references": [
          "b4558669-5193-4350-b721-99967a38fda6",
          "72547098-4b09-4921-81bd-4a5aecc89609"
        ],
        "stereo_centers": 0
      },
      "unii": "JGX76Y85M6"
    }
  ]
}