{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "ef5f5c97-dc92-0231-1866-fd3940c9499f",
          "code": "IV3S2HH53G",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=IV3S2HH53G",
          "code_system": "DAILYMED",
          "references": [
            "708e2bc1-6d02-a77c-cdac-3f3f3dcdf181"
          ]
        },
        {
          "uuid": "d7472a7e-f862-46ca-87a6-9d7a8ddb8f4f",
          "code": "IV3S2HH53G",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "65ab0e13-1bd1-cbb1-2a40-8e9a5b85066e",
          "code": "84695-99-8",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=84695-99-8",
          "code_system": "CAS",
          "references": [
            "a21e2e8b-b748-378a-320c-b427260f9a5b"
          ]
        },
        {
          "uuid": "19851030-2cc1-7f12-b261-8ac164db87db",
          "code": "283-619-0",
          "type": "PRIMARY",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "a21e2e8b-b748-378a-320c-b427260f9a5b"
          ]
        },
        {
          "uuid": "b34f2037-97f2-4ee9-d114-0fc35eae92e9",
          "code": "DTXSID701042246",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID701042246",
          "code_system": "EPA CompTox"
        }
      ],
      "relationships": [
        {
          "uuid": "b3b71222-4a85-4801-8f9a-d3fe45751d5b",
          "amount": {
            "uuid": "812d3228-56af-431b-b6f3-4c92e8de0c25"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "664428c0-f2cc-4606-b501-76a13a6985dd",
            "refuuid": "93d1918b-05b1-4d64-a634-6c7b6d2f5099",
            "name": "CASTANEA SATIVA LEAF",
            "unii": "IV3S2HH53G",
            "linking_id": "IV3S2HH53G",
            "ref_pname": "CASTANEA SATIVA LEAF",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "structurallyDiverse",
      "names": [
        {
          "uuid": "2001611c-960c-47d9-ae5f-8ab8d4d86ab0",
          "name": "CASTANEA CASTANEA LEAF",
          "stdName": "CASTANEA CASTANEA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "be629c35-fbf6-47a6-9762-96e2d2a35106",
          "name": "CASTANEA PROLIFERA LEAF",
          "stdName": "CASTANEA PROLIFERA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "af004fd3-169b-34cb-06bd-013e4f4f3d53",
          "name": "CASTANEA SATIVA (CHESTNUT) LEAF EXTRACT",
          "stdName": "CASTANEA SATIVA (CHESTNUT) LEAF EXTRACT",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "145b2e83-5af7-53ab-8d2a-f17142309fa0",
            "2936acff-1b34-3b60-1e86-e6d7df24981e",
            "8062563b-2197-61db-d53d-2e7f828530b4",
            "fcae8f92-7497-a869-4e18-9eef48606b6f"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "91da1b12-d65a-5d89-e6f8-d05cab4d6d9c",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "36bdaa31-00f8-431b-8e38-4e6ef65b22a8",
          "name": "CASTANEA SATIVA LEAF",
          "stdName": "CASTANEA SATIVA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "1064b645-8357-454b-88fd-3df6b83e459e",
            "713e4e96-d357-4ad8-acc0-6a47cba8d50d",
            "8f2fe634-3a83-469f-b0ac-ff88f2956590",
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": true
        },
        {
          "uuid": "250ddef3-69f6-4e8f-ba91-0d6336457d73",
          "name": "CASTANEA VESCA",
          "stdName": "CASTANEA VESCA",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "711a0f1d-b09a-4d6d-bf6e-9ac003d01977",
            "a5591ad9-3542-4289-8397-57401669c17e",
            "b413016d-90d5-4f23-9205-524d94908554",
            "c26e0a3d-0831-424f-9ad4-c0b7dbab8645"
          ],
          "display_name": false
        },
        {
          "uuid": "4be23817-2334-47ea-b97a-40482807d8d1",
          "name": "CASTANEA VESCA LEAF",
          "stdName": "CASTANEA VESCA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "921987fc-c048-4acc-b70f-9f1a1a713063",
          "name": "CASTANEA VESCA [HPUS]",
          "stdName": "CASTANEA VESCA [HPUS]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c26e0a3d-0831-424f-9ad4-c0b7dbab8645",
            "a5591ad9-3542-4289-8397-57401669c17e"
          ],
          "display_name": false
        },
        {
          "uuid": "b2e10418-46f5-4ebd-8f1f-024884b751d9",
          "name": "CASTANEA VULGARIS LEAF",
          "stdName": "CASTANEA VULGARIS LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "36ceb72e-3de8-7075-9f32-3f062208cc6c",
          "name": "Castanea sativa leaf [WHO-DD]",
          "stdName": "CASTANEA SATIVA LEAF [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "6a3b0e66-e308-e870-7ca6-06f0a1027a05"
          ],
          "display_name": false
        },
        {
          "uuid": "3361f695-84ed-4b32-8766-df24d056783a",
          "name": "EURASIAN CHESTNUT LEAF",
          "stdName": "EURASIAN CHESTNUT LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "63f4d1dc-48c4-469c-a4c4-df0591917554",
            "45ef1e58-816d-410b-840a-2b6e11dbeef8"
          ],
          "display_name": false
        },
        {
          "uuid": "4cd0a6d4-f6f1-4d91-a9f3-70b8015f918a",
          "name": "EUROPEAN CHESTNUT LEAF",
          "stdName": "EUROPEAN CHESTNUT LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d4daa8f0-c661-4a2f-9f29-b3c4829508ed"
          ],
          "display_name": false
        },
        {
          "uuid": "eb31cb27-d877-462a-87b0-e6bfa9acd24a",
          "name": "FAGUS CASTANEA LEAF",
          "stdName": "FAGUS CASTANEA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "5c5f1c5e-1bef-4a28-bedb-26139ec8cf90",
          "name": "FAGUS PROCERA LEAF",
          "stdName": "FAGUS PROCERA LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "955e3728-4c4e-479a-9791-2b07edf933a0",
            "413c0f6e-0e17-49f3-b813-a5b6d31ad65a"
          ],
          "display_name": false
        },
        {
          "uuid": "aa93067e-a138-4d4c-9ae2-ea10f5fba29f",
          "name": "SPANISH CHESNUT LEAF",
          "stdName": "SPANISH CHESNUT LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9e67924d-b18a-4570-8be8-4dbcfe3cbf38",
            "b73926fb-0c3e-4bab-9043-2ceeea9b6322"
          ],
          "display_name": false
        },
        {
          "uuid": "d04dcd4c-e475-401c-b030-ff9a7a8faadd",
          "name": "SWEET CHESTNUT LEAF",
          "stdName": "SWEET CHESTNUT LEAF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "037ddd36-0869-47e7-bbe5-658b4db0ff97"
          ],
          "display_name": false
        },
        {
          "uuid": "0daffa32-e010-428c-8222-013779195ea8",
          "name": "SWEET CHESTNUT [MART.]",
          "stdName": "SWEET CHESTNUT [MART.]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "369bdebf-43bf-4d9c-82b9-46c3c4b1fe2b",
            "41733476-5481-4b0a-8189-ba2a253b5ad2"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "c26e0a3d-0831-424f-9ad4-c0b7dbab8645",
          "citation": "HPUS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "711a0f1d-b09a-4d6d-bf6e-9ac003d01977",
          "citation": "DL",
          "doc_type": "HOMEOPATHIC PHARMACOPOEIA US",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "955e3728-4c4e-479a-9791-2b07edf933a0",
          "citation": "KEW",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "413c0f6e-0e17-49f3-b813-a5b6d31ad65a",
          "citation": "KEW GARDENS (WCPS)",
          "doc_type": "KEW GARDENS (WCPS)",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "63f4d1dc-48c4-469c-a4c4-df0591917554",
          "citation": "TROPICOS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "45ef1e58-816d-410b-840a-2b6e11dbeef8",
          "citation": "TROPICOS",
          "doc_type": "TROPICOS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d4daa8f0-c661-4a2f-9f29-b3c4829508ed",
          "citation": "ITIS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9e67924d-b18a-4570-8be8-4dbcfe3cbf38",
          "citation": "HOC 2",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b73926fb-0c3e-4bab-9043-2ceeea9b6322",
          "citation": "HERBS OF COMMERCE",
          "doc_type": "HERBS OF COMMERCE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "037ddd36-0869-47e7-bbe5-658b4db0ff97",
          "citation": "Wikipedia",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a5591ad9-3542-4289-8397-57401669c17e",
          "citation": "HPUS 2011",
          "doc_type": "HOMEOPATHIC PHARMACOPOEIA US",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "369bdebf-43bf-4d9c-82b9-46c3c4b1fe2b",
          "citation": "MART",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "41733476-5481-4b0a-8189-ba2a253b5ad2",
          "citation": "MARTINDALE",
          "doc_type": "MARTINDALE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1064b645-8357-454b-88fd-3df6b83e459e",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "713e4e96-d357-4ad8-acc0-6a47cba8d50d",
          "citation": "WHO DRUG DICTIONARY",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "51841492-156c-4bfa-bbbd-badea590e586",
          "citation": "SRS import [IV3S2HH53G]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=IV3S2HH53G",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391314000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3a80b173-1e12-4243-a539-8f1eb56431fd",
          "citation": "Catalog of Life 2009",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b413016d-90d5-4f23-9205-524d94908554",
          "citation": "CASTANEA VESCA [HPUS]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "8f2fe634-3a83-469f-b0ac-ff88f2956590",
          "citation": "CASTANEA SATIVA LEAF [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "708e2bc1-6d02-a77c-cdac-3f3f3dcdf181",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "6a3b0e66-e308-e870-7ca6-06f0a1027a05",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "145b2e83-5af7-53ab-8d2a-f17142309fa0",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "2936acff-1b34-3b60-1e86-e6d7df24981e",
          "citation": "INCI",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fcae8f92-7497-a869-4e18-9eef48606b6f",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a21e2e8b-b748-378a-320c-b427260f9a5b",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391314000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8062563b-2197-61db-d53d-2e7f828530b4",
          "citation": "CASTANEA SATIVA (CHESTNUT) LEAF EXTRACT [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "9e2c5f68-5e23-4a7e-bf05-55067091ddf7",
          "citation": "PCPC",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "93d1918b-05b1-4d64-a634-6c7b6d2f5099",
      "version": "9",
      "structurally_diverse": {
        "uuid": "c0874540-db79-47ea-9e20-bbedce1ac939",
        "parent_substance": {
          "uuid": "14875d8f-76a8-479f-b777-96ee6c2ee615",
          "refuuid": "385cd80f-4ffc-4c52-b492-dd658d6c400e",
          "name": "CASTANEA SATIVA WHOLE",
          "unii": "DK55N3C1AK",
          "linking_id": "DK55N3C1AK",
          "ref_pname": "CASTANEA SATIVA WHOLE",
          "substance_class": "reference"
        },
        "part": [
          "leaf"
        ],
        "references": [
          "3a80b173-1e12-4243-a539-8f1eb56431fd",
          "51841492-156c-4bfa-bbbd-badea590e586"
        ],
        "source_material_class": "ORGANISM",
        "source_material_type": "PLANT"
      },
      "modifications": {
        "uuid": "59a144ab-4a7e-45f4-a252-350a98f9e5d0"
      },
      "unii": "IV3S2HH53G"
    }
  ]
}