{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "8873c696-bc15-4a40-ae14-8e74fabef95c",
          "code": "Norepinephrine transporter",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Norepinephrine_transporter",
          "code_system": "WIKIPEDIA",
          "references": [
            "0aef3b48-6458-d48f-e303-6811e1a4e19e"
          ]
        },
        {
          "uuid": "b6794e01-05ba-4694-bd0b-768187f426cb",
          "code": "P23975",
          "type": "PRIMARY",
          "url": "http://www.uniprot.org/uniprot/P23975",
          "code_system": "UNIPROT",
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ]
        },
        {
          "uuid": "8a0daf11-b215-4095-9b04-0a08a5975fcc",
          "code": "HN86OLH1NW",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        }
      ],
      "relationships": [
        {
          "uuid": "334d88cd-d7ac-4542-ab4c-38c87fa1d63b",
          "type": "INHIBITOR->TARGET",
          "references": [
            "660a63e5-9f50-4fd7-9742-e02d5e289109"
          ],
          "related_substance": {
            "uuid": "492f706e-757a-485a-801b-949124aa588b",
            "refuuid": "05257bbb-96c3-454b-ba07-a2d3031d6c66",
            "name": "BELOXEPIN",
            "unii": "G905IN29U4",
            "linking_id": "G905IN29U4",
            "ref_pname": "BELOXEPIN"
          }
        },
        {
          "uuid": "5ab31037-262a-4a49-be2b-97c80611825d",
          "amount": {
            "uuid": "23fa2652-dd34-40f1-9602-e3b956a32087",
            "average": 192,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "interaction_type": "IN-VITRO",
          "references": [
            "d450edd1-0b4e-d1e2-3f35-9f798e5b4278"
          ],
          "related_substance": {
            "uuid": "c927eafb-859f-4396-8231-4c3159764222",
            "refuuid": "ed2b6e8e-2f51-4b2b-9ad7-80fd4f4c850d",
            "name": "NIRAPARIB",
            "unii": "HMC2H89N35",
            "linking_id": "HMC2H89N35",
            "ref_pname": "NIRAPARIB",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "3b699f1a-c17d-4fed-993a-7b198ef2cc7f",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "e5c6841b-c009-4adc-8fa5-98de6711a874",
            "refuuid": "72cf8b31-db34-4a56-9158-1340e3028389",
            "name": "Duloxetine",
            "unii": "O5TNM5N07U",
            "linking_id": "O5TNM5N07U",
            "ref_pname": "Duloxetine"
          }
        },
        {
          "uuid": "e536314f-323a-4ba0-a1f4-5e87e54bb066",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "3fe97e93-4f76-467b-a77b-a49449216aec",
            "refuuid": "ad1035e3-bc18-4070-bf61-d4a96bc7c531",
            "name": "PSEUDOEPHEDRINE",
            "unii": "7CUC9DDI9F",
            "linking_id": "7CUC9DDI9F",
            "ref_pname": "PSEUDOEPHEDRINE"
          }
        },
        {
          "uuid": "9b40c909-f1c4-48f5-a93a-b7db300350d5",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "3551ce9f-7da4-4672-98c0-29eb5d3411d9",
            "refuuid": "35d4616c-2bf4-429f-81d9-d0dc84c22703",
            "name": "NETARSUDIL",
            "unii": "W6I5QDT7QI",
            "linking_id": "W6I5QDT7QI",
            "ref_pname": "NETARSUDIL"
          }
        },
        {
          "uuid": "8679f9af-7579-4abd-9bfd-85791496cbf5",
          "amount": {
            "uuid": "433b83aa-e49c-4fc8-baaf-c67f28f82318"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "129d868d-8ce5-4ac7-a69f-d07e1a093227"
          ],
          "related_substance": {
            "uuid": "2a303646-bcdd-4fd2-a9e5-e47860b70128",
            "refuuid": "641da427-eeba-4ff8-95df-0eb81628f1b6",
            "name": "FLUBROBENGUANE F-18",
            "unii": "8LF7W971UM",
            "linking_id": "8LF7W971UM",
            "ref_pname": "FLUBROBENGUANE F-18"
          }
        },
        {
          "uuid": "3864f9be-5a12-4b4e-897c-f63a4354c9b1",
          "type": "INHIBITOR->TARGET",
          "references": [
            "266c02ba-6983-4a11-8ad7-628fc2f7701f"
          ],
          "related_substance": {
            "uuid": "05ecea95-15cb-4d58-a166-bb987b2fad5b",
            "refuuid": "64148c70-b89e-48dd-8f9e-084bc0f7e2ed",
            "name": "TRAMADOL, (-)-",
            "unii": "26J30IC20Q",
            "linking_id": "26J30IC20Q",
            "ref_pname": "TRAMADOL, (-)-"
          }
        },
        {
          "uuid": "4fad25f2-2ebf-497e-8d8a-982138ba5ecb",
          "amount": {
            "uuid": "3ef84c47-5c5d-4527-aeb3-41ccab8fcc63"
          },
          "comments": "(−)-tramadol inhibits norepinephrine reuptake",
          "type": "INHIBITOR->TARGET",
          "references": [
            "37bbea26-e349-4df2-b37b-ee62b49c5f04"
          ],
          "related_substance": {
            "uuid": "142854de-47ab-41f9-a8ea-97a30452363c",
            "refuuid": "2966d491-86e8-429b-85e9-cd22e4f13278",
            "name": "TRAMADOL",
            "unii": "39J1LGJ30J",
            "linking_id": "39J1LGJ30J",
            "ref_pname": "TRAMADOL"
          }
        },
        {
          "uuid": "2e6df7f0-7dbe-45c5-98a1-a81ff1a92882",
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "19546650-86a5-4d37-a76f-832e76631e01"
          ],
          "related_substance": {
            "uuid": "abcd8a1f-5c18-47ef-946e-abdb2cb8a0d7",
            "refuuid": "92358dca-d41c-4c1a-823a-acbbf3fc3663",
            "name": "INER I-123",
            "unii": "8AAP8G8ODE",
            "linking_id": "8AAP8G8ODE",
            "ref_pname": "INER I-123"
          }
        },
        {
          "uuid": "73054a34-6698-4656-a2b7-070d09560253",
          "type": "INHIBITOR->TARGET",
          "references": [
            "2cccdcb6-c122-43e9-a500-d7a9612b6f06",
            "1b0e39dc-f2cf-4f8e-a8de-ce9359e25803"
          ],
          "related_substance": {
            "uuid": "44493b60-3cc8-4992-bfa3-135bf8c63fbd",
            "refuuid": "9e7b9375-4226-4e2b-9416-1e8e975fb529",
            "name": "AMPRELOXETINE",
            "unii": "19997EZ42I",
            "linking_id": "19997EZ42I",
            "ref_pname": "AMPRELOXETINE"
          }
        },
        {
          "uuid": "9f3a6082-3315-4277-8452-ad226994735c",
          "amount": {
            "uuid": "6e38b3ef-239b-402b-a71e-d9f100d6e952",
            "average": 3700,
            "units": "NANOMOLAR"
          },
          "qualification": "Ki",
          "type": "INHIBITOR->TARGET",
          "references": [
            "676f70e3-9171-44ba-a8fa-1ef70c50eabb"
          ],
          "related_substance": {
            "uuid": "ba2e27fe-5c89-496f-ad01-2919b8454258",
            "refuuid": "675e67dd-4528-4022-b276-3350c6f50dc4",
            "name": "Solriamfetol",
            "unii": "939U7C91AI",
            "linking_id": "939U7C91AI",
            "ref_pname": "Solriamfetol"
          }
        },
        {
          "uuid": "049fbf6f-7804-4a7b-be7e-06f4aa96cc30",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "91ff8377-f92f-462b-8419-3feb416da3c3",
            "refuuid": "d7a59c80-f981-4adb-b1d3-87d4df291ffc",
            "name": "Amitriptyline",
            "unii": "1806D8D52K",
            "linking_id": "1806D8D52K",
            "ref_pname": "Amitriptyline",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "aa72540c-5d15-46ad-b1e0-4baa0aeb7903",
          "amount": {
            "uuid": "b95c01da-a941-4e9d-bd22-ef2528495702"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "dca4f38e-7592-47e3-8db5-d9d871baf30c"
          ],
          "related_substance": {
            "uuid": "daaf344d-b20f-444d-b733-c6691925562b",
            "refuuid": "bf549764-98f7-45ac-8e43-9e879aae0754",
            "name": "IMIPRAMINE",
            "unii": "OGG85SX4E4",
            "linking_id": "OGG85SX4E4",
            "ref_pname": "IMIPRAMINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "59a4995f-e5da-403a-9fb1-d5c6f217ac63",
          "type": "SUBSTRATE->TARGET",
          "references": [
            "bb8b3e68-77f0-4937-baa7-311a7df6370a"
          ],
          "related_substance": {
            "uuid": "674ce178-853d-4e95-9169-53b3cda13bc3",
            "refuuid": "1d62082b-fca3-48c4-aba2-7ccee7ca14ff",
            "name": "IOBENGUANE I-131",
            "unii": "Q461L7AK4R",
            "linking_id": "Q461L7AK4R",
            "ref_pname": "IOBENGUANE I-131"
          }
        },
        {
          "uuid": "43bceb32-a02d-4696-88c3-c01741c0b23b",
          "amount": {
            "uuid": "1b0a2253-82e5-42f6-9b68-40c6fc8ba986",
            "average": 12,
            "units": "NANOMOLAR"
          },
          "qualification": "Ki",
          "type": "INHIBITOR->TARGET",
          "references": [
            "1ec9db76-e10b-41bb-ab34-9add1f9a0429"
          ],
          "related_substance": {
            "uuid": "f0117baa-62e9-4c42-a68e-8e267390f25c",
            "refuuid": "10e9978a-e5a9-4c28-96db-a34a4f76fc53",
            "name": "Norquetiapine",
            "unii": "V3H1ZVV9S6",
            "linking_id": "V3H1ZVV9S6",
            "ref_pname": "Norquetiapine"
          }
        },
        {
          "uuid": "7208e341-06ec-4223-a2ab-26154865da4f",
          "amount": {
            "uuid": "a2040698-025f-4586-8dee-172bfcc454e3",
            "average": 535,
            "units": "NANOMOLAR"
          },
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "9ae52a90-36bd-41a1-8db8-6ccfbf2ba04a",
            "refuuid": "92ab23e1-a435-47c7-b5a9-3312f26acfe7",
            "name": "VENLAFAXINE",
            "unii": "GRZ5RCB1QG",
            "linking_id": "GRZ5RCB1QG",
            "ref_pname": "VENLAFAXINE"
          }
        },
        {
          "uuid": "1461766d-d262-4205-9076-3e5c50925771",
          "amount": {
            "uuid": "57064f88-3bda-4f99-9eaa-5f92b6d8701e"
          },
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "34685794-15ef-4b5e-b477-8e4606ab9c5a",
            "refuuid": "e67d9259-3150-42a6-879a-08354532a492",
            "name": "1-(2,6-DIFLUOROPHENYL)-3-(2-PIPERAZIN-1-YLETHYL)-1,3-DIHYDRO-2,1,3-BENZOTHIADIAZOLE 2,2-DIOXIDE",
            "unii": "PFW9A4FSE8",
            "linking_id": "PFW9A4FSE8",
            "ref_pname": "1-(2,6-DIFLUOROPHENYL)-3-(2-PIPERAZIN-1-YLETHYL)-1,3-DIHYDRO-2,1,3-BENZOTHIADIAZOLE 2,2-DIOXIDE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "43c41d80-141e-4902-a22a-1909dfb98701",
          "amount": {
            "uuid": "6346af3d-8f2c-4cd4-91fc-e2bbd4e91f9e"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "94f42d79-6e57-4fe6-a9d6-7350204c63ea"
          ],
          "related_substance": {
            "uuid": "374bb25a-5ff5-41a1-8733-9442be6b579d",
            "refuuid": "e37d28ad-1ddb-44f7-b84d-7e6b6aeb84ba",
            "name": "3-HYDROXYEPHEDRINE, C-11",
            "unii": "VFB6950Q3Y",
            "linking_id": "VFB6950Q3Y",
            "ref_pname": "3-HYDROXYEPHEDRINE, C-11",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "a4bcbe71-390b-45cd-920b-abc800b6c586",
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "68eb8857-12f9-426f-9360-3b6c9838a587"
          ],
          "related_substance": {
            "uuid": "d9fc2198-4840-46ed-96ab-88ba9b98af8f",
            "refuuid": "75aa22cb-53eb-4cf0-ad79-88811d78fcc4",
            "name": "3-METHYL-PCPY",
            "unii": "FS9Z5C7CQ5",
            "linking_id": "FS9Z5C7CQ5",
            "ref_pname": "3-METHYL-PCPY"
          }
        },
        {
          "uuid": "d97b8781-53f2-4d8d-b3e0-793885e5423e",
          "amount": {
            "uuid": "8c0b009e-988d-4dd9-88a7-5ce5553b025c"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "interaction_type": "IN RAT",
          "references": [
            "c95a9f6f-bb81-40d6-b353-37df88880baa"
          ],
          "related_substance": {
            "uuid": "62e59aaf-2dac-4f82-a5c4-cfc36c62178f",
            "refuuid": "2aec2653-7f96-4c04-a277-51423c47e131",
            "name": "6-METHYL-MDA",
            "unii": "ZXQ5PQR4TU",
            "linking_id": "ZXQ5PQR4TU",
            "ref_pname": "6-METHYL-MDA"
          }
        },
        {
          "uuid": "45f5fc28-1c16-496a-8021-807c55ec1974",
          "amount": {
            "uuid": "3355f322-f8e8-4f8d-b7ef-7ad913f38044"
          },
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "38357acf-a19b-4ab8-bdc3-ba7d3cf345d4",
            "refuuid": "960e94ef-dfae-48c2-b08f-81e6ffd7e331",
            "name": "TAPENTADOL",
            "unii": "H8A007M585",
            "linking_id": "H8A007M585",
            "ref_pname": "TAPENTADOL",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "41c54b25-02c1-4817-aeca-d209f240a0e4",
          "amount": {
            "uuid": "7cff49f4-cdce-4b5d-b4ce-d0bf264482e6"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "e5cd8a3a-2c55-4588-af72-d358b7a7133b"
          ],
          "related_substance": {
            "uuid": "ecbc87a0-f0dd-4200-9280-6d739750b175",
            "refuuid": "2618bdb1-05e9-4705-a299-59d96ca73c5e",
            "name": "RTI-120",
            "unii": "532Y5K4NMA",
            "linking_id": "532Y5K4NMA",
            "ref_pname": "RTI-120"
          }
        },
        {
          "uuid": "8bd509ee-63e9-4541-bad9-064cd96da9b5",
          "amount": {
            "uuid": "06be6c88-edfc-450e-beac-6a67386c1ca8"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "d318d14a-a871-4a69-960b-76d125510c0f"
          ],
          "related_substance": {
            "uuid": "6a19bd40-a98e-4d6e-87e8-f6e22cde6d52",
            "refuuid": "1844b7f4-2f22-4f90-9230-fa0ecaa5e83d",
            "name": "DIPHENYLPROLINOL",
            "unii": "54U9UN7HN4",
            "linking_id": "54U9UN7HN4",
            "ref_pname": "DIPHENYLPROLINOL"
          }
        },
        {
          "uuid": "8a28127b-83e2-4457-b715-37f7f044ba64",
          "amount": {
            "uuid": "e09f0661-cdeb-444e-aa95-29babb70ba36"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "1c344cb1-0ce2-4521-9e2f-55a4262db9fe"
          ],
          "related_substance": {
            "uuid": "e2c571fd-167e-499a-91b1-603fb78e8b0b",
            "refuuid": "17491b35-f79b-4635-980a-97f8e7906644",
            "name": "WY-46824",
            "unii": "99T4HMN9HV",
            "linking_id": "99T4HMN9HV",
            "ref_pname": "WY-46824"
          }
        },
        {
          "uuid": "a7739f66-ce4c-408b-a967-d3301c04bcd4",
          "amount": {
            "uuid": "4e1bac62-4d69-4763-8543-565f5ea17fe3",
            "average": 3100,
            "units": "NANOMOLAR"
          },
          "comments": "The weak monoaminergic activity of DPIA suggest no major pharmacological contribution when present in street amphetamine",
          "type": "WEAK INHIBITOR->TARGET",
          "references": [
            "a152c30c-9686-44b4-969d-4583fc3b2ea2"
          ],
          "related_substance": {
            "uuid": "0e742e01-ca13-47b3-a237-22a3dbdb4b2d",
            "refuuid": "7d1900c3-1b50-4486-9aa3-9a1a99d851ec",
            "name": "DPIA",
            "unii": "HNZ7L49KE6",
            "linking_id": "HNZ7L49KE6",
            "ref_pname": "DPIA",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "55f650db-59fb-4846-aabe-ef3387ebfcad",
          "amount": {
            "uuid": "dcafca2d-883e-4f32-83f5-01511f2b439c",
            "average": 180,
            "units": "NANOMOLAR"
          },
          "qualification": "Ki",
          "type": "INHIBITOR->TARGET",
          "references": [
            "7a909ecf-c74a-4f78-b98e-30144c527db4"
          ],
          "related_substance": {
            "uuid": "0d3878ef-2a3b-4652-bb34-f51b187f4800",
            "refuuid": "fb5117e3-c8d9-4411-8c10-10074af28716",
            "name": "5-APB",
            "unii": "2M3825704H",
            "linking_id": "2M3825704H",
            "ref_pname": "5-APB",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "f2953259-7b07-46f1-86f3-c086c4ad8075",
          "amount": {
            "uuid": "184a3d6a-8dcf-42cb-b654-a0023c0153a9"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "c90e0530-3c5e-438a-8485-8a411f70063a"
          ],
          "related_substance": {
            "uuid": "0ee48144-a809-45f3-a4e9-64505669095c",
            "refuuid": "7e86cefd-835a-4239-8f54-0bbef7b6ebe7",
            "name": "JZ-IV-10",
            "unii": "GYT6ACY5JL",
            "linking_id": "GYT6ACY5JL",
            "ref_pname": "JZ-IV-10"
          }
        },
        {
          "uuid": "9d5c9d9e-9e37-4e15-8bb3-381019f1cd65",
          "amount": {
            "uuid": "3a44e3ae-6d93-4b10-8e65-d8e25cc8aa16"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "a5f24767-7859-4a07-bb5e-35b1bb242e21"
          ],
          "related_substance": {
            "uuid": "942ae2e2-43a4-40f3-8374-8308e3d1c9e5",
            "refuuid": "ac43e7aa-ec0e-42ab-9e8d-3c05e6725be0",
            "name": "1-(3-Chlorophenyl)-4-(2-phenylethyl)piperazine",
            "unii": "3LEH2E7AEU",
            "linking_id": "3LEH2E7AEU",
            "ref_pname": "1-(3-Chlorophenyl)-4-(2-phenylethyl)piperazine"
          }
        },
        {
          "uuid": "f1a0f73b-0ef1-4569-a757-767d7e346914",
          "amount": {
            "uuid": "3889de8f-641e-4f7c-ba48-9029d4d955a7"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "a2c15105-1b1c-4ae0-905e-7071ed6137b5"
          ],
          "related_substance": {
            "uuid": "cadf7e16-ea06-453e-8b29-69a221f58b01",
            "refuuid": "72b3b48b-2d6b-42c7-90a3-d19ff6d714f0",
            "name": "TANDAMINE",
            "unii": "6L5FH5A43E",
            "linking_id": "6L5FH5A43E",
            "ref_pname": "TANDAMINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "394e66e3-7136-4ab0-afd1-cdb3e8397c48",
          "amount": {
            "uuid": "60297e8d-e4cd-479d-92d3-e107018aab6e"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "32003b56-6bd2-481a-a227-bf6aacd769f2"
          ],
          "related_substance": {
            "uuid": "bbf222f8-74d7-46ac-a841-9f31e46e1eff",
            "refuuid": "77cd57a5-f55d-429d-8007-8333c364212a",
            "name": "WF-23",
            "unii": "7KN3H3NMW6",
            "linking_id": "7KN3H3NMW6",
            "ref_pname": "WF-23"
          }
        },
        {
          "uuid": "e4d0673d-903e-4d20-9879-f4b59159e651",
          "amount": {
            "uuid": "652c0fda-3a36-4ecf-a9f8-467f7b19c57d",
            "average": 108,
            "high": 123,
            "low": 93,
            "units": "NANOMOLAR"
          },
          "comments": "Inhibition of [3H]Neurotransmitter Uptake",
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "40fcd0e7-acee-4fc8-b098-af7b236e330a",
            "refuuid": "f4ef2cfe-9693-4135-b4f3-d04a9595a9ac",
            "name": "MIDOMAFETAMINE",
            "unii": "KE1SEN21RM",
            "linking_id": "KE1SEN21RM",
            "ref_pname": "MIDOMAFETAMINE"
          }
        },
        {
          "uuid": "7ae8eb13-6f26-4acb-870d-687d42c6903d",
          "amount": {
            "uuid": "aa1c988e-e72e-47d3-a322-1541d3e238d1",
            "average": 530,
            "high": 580,
            "low": 480,
            "units": "NANOMOLAR"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "fed3b02b-977e-4d7c-88cb-5a5e9d647443"
          ],
          "related_substance": {
            "uuid": "004b0625-e098-44f5-b245-282b40aeac95",
            "refuuid": "720e6bd8-9aa7-4473-be81-4438726f64cf",
            "name": "MDMC",
            "unii": "L4I4B1R01F",
            "linking_id": "L4I4B1R01F",
            "ref_pname": "MDMC",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "ab10973c-3f28-4369-a768-a18d4ae416fb",
          "amount": {
            "uuid": "dd1ccfda-6795-4e58-bcf5-b8a36b17e7ca",
            "average": 920,
            "high": 1050,
            "low": 790,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "52a00883-c6b7-47c6-9c8b-efffc30a271f",
            "refuuid": "00947d5e-cd7a-4f6e-a66f-9f4f096fc422",
            "name": "BUTYLONE",
            "unii": "X72T4EQ4FQ",
            "linking_id": "X72T4EQ4FQ",
            "ref_pname": "BUTYLONE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "7d9cf24b-26bf-47e1-bb5e-40e219eeefba",
          "amount": {
            "uuid": "08b45d52-5411-4978-a793-126e83335b55"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "da66c5f5-94f0-4c94-9eae-5ce3aa5369f7"
          ],
          "related_substance": {
            "uuid": "839b3232-c78d-47bc-8e19-d4456545be63",
            "refuuid": "ce404087-d9b6-4eba-b1cf-0e6f093715ad",
            "name": "MENER, (S,S)-C-11",
            "unii": "44MR98LU8P",
            "linking_id": "44MR98LU8P",
            "ref_pname": "MENER, (S,S)-C-11",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "0fb56481-d188-4564-bb25-7218d2d05c7c",
          "amount": {
            "uuid": "aaa75a37-93c1-40ef-862e-bdd5e73dd578"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "5539ae9a-0563-4de8-8b18-c2e858634afd"
          ],
          "related_substance": {
            "uuid": "f2cd2455-519f-47be-8b2e-ade3125e41bf",
            "refuuid": "d80100ac-f6b0-4a88-be7d-25d4acab5967",
            "name": "MENET C-11",
            "unii": "VA46LC5AZQ",
            "linking_id": "VA46LC5AZQ",
            "ref_pname": "MENET C-11",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "8c15d0b7-18e9-4563-9ad9-df050d325105",
          "amount": {
            "uuid": "5d52edf0-09a0-4727-9f55-decb04ce8bee"
          },
          "type": "LIGAND->TRANSPORTER",
          "references": [
            "dc1f9a7b-a03b-4aac-8d8e-4642b091ec6d"
          ],
          "related_substance": {
            "uuid": "6956269f-d2ca-4c7b-bc31-542857bab406",
            "refuuid": "b4d065bd-88cb-4900-a865-41f9425bc8f2",
            "name": "2'-HYDROXYCOCAINE",
            "unii": "K8J4W658QK",
            "linking_id": "K8J4W658QK",
            "ref_pname": "2'-HYDROXYCOCAINE"
          }
        },
        {
          "uuid": "b49b92c0-bb00-47f5-a803-65f1bd3f3fc6",
          "type": "INHIBITOR->TRANSPORTER",
          "interaction_type": "IN-VITRO",
          "references": [
            "af580592-14be-4a0c-abeb-9b80bb7bbe03"
          ],
          "related_substance": {
            "uuid": "5b8d531d-1adb-466a-a00f-d903c2efc809",
            "refuuid": "f7960d9b-4c3b-44c2-9992-3d445eab22df",
            "name": "RTI-112",
            "unii": "TDD7WP3S39",
            "linking_id": "TDD7WP3S39",
            "ref_pname": "RTI-112"
          }
        },
        {
          "uuid": "8110ec2e-7250-4c85-97af-d86e09d80c70",
          "amount": {
            "uuid": "2a74699b-ec40-4a02-b5dd-26f4216d3eb3"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "c747d1ee-9173-48f7-8325-3c65e6ef5748"
          ],
          "related_substance": {
            "uuid": "f528fdf8-dd0e-4ca3-b427-384432a9802d",
            "refuuid": "5c8cd4e5-b279-48ae-af3a-d26a83ddf84e",
            "name": "PRC200-SS",
            "unii": "V9MLT2S334",
            "linking_id": "V9MLT2S334",
            "ref_pname": "PRC200-SS"
          }
        },
        {
          "uuid": "00870716-2506-4d0e-acf0-3a95f0d36d70",
          "amount": {
            "uuid": "3d6ec0ed-4086-4c8d-b806-ca3068f5a6a6"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "8ec5afb3-574b-4c70-8b37-fa2bd45f007f"
          ],
          "related_substance": {
            "uuid": "ba93f977-6d11-4b92-b98e-c15eef5a1ae1",
            "refuuid": "c14e0d5d-b64b-4be8-8bdd-52650849fe29",
            "name": "ATOMOXETINE",
            "unii": "ASW034S0B8",
            "linking_id": "ASW034S0B8",
            "ref_pname": "ATOMOXETINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "8cac8e5d-ee5a-40b4-b53d-6e52a196e0c4",
          "amount": {
            "uuid": "adbb45fc-0e30-4f67-8bb9-378e6dc9adb7"
          },
          "type": "INHIBITOR->TRANSPORTER",
          "references": [
            "f52ff1e1-335c-484d-bc2a-3036b181a00f"
          ],
          "related_substance": {
            "uuid": "213e77e6-1cb0-4cea-b558-458ba90c9cbb",
            "refuuid": "e2e779e7-5614-4256-86f6-6e20680992f4",
            "name": "N-METHYL-PPPA",
            "unii": "C6C3GB68TV",
            "linking_id": "C6C3GB68TV",
            "ref_pname": "N-METHYL-PPPA"
          }
        },
        {
          "uuid": "6217217a-a491-48a7-a66f-746063bedaa2",
          "amount": {
            "uuid": "dc8ce455-f979-45d5-ae53-0a319ac4b585"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "735a26e6-bb52-407f-ba0a-f068a6d49c67"
          ],
          "related_substance": {
            "uuid": "8abf3022-deaf-4d22-bef0-7d59870c7629",
            "refuuid": "f235e668-f491-4144-8f74-dcf01409ae54",
            "name": "GMO C-11",
            "unii": "P7G9TGX966",
            "linking_id": "P7G9TGX966",
            "ref_pname": "GMO C-11",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "22b984bb-cb4e-4c13-aff7-38b2baf7f1e1",
          "amount": {
            "uuid": "330d600f-dc5a-4513-8103-3a8e89b4b1e7"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "06cdeda4-7a57-471c-b94f-6c8c7dd58f20"
          ],
          "related_substance": {
            "uuid": "7b8dd49c-3af8-4ba8-905c-f029ffb633de",
            "refuuid": "5ac90935-e4f7-42d1-b121-cbd0dfd198ed",
            "name": "RO-15-8081 FREE BASE",
            "unii": "J6EIG6Q478",
            "linking_id": "J6EIG6Q478",
            "ref_pname": "RO-15-8081 FREE BASE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "bc99bbab-8e39-4c1c-9ceb-c19162ae6e68",
          "amount": {
            "uuid": "91c268ad-a076-4454-be03-043a7fa3b43e",
            "average": 3700,
            "units": "NANOMOLAR"
          },
          "comments": "Could be target",
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "references": [
            "d2a242bb-8538-4666-a2bb-1acecac3dc88"
          ],
          "related_substance": {
            "uuid": "d1a897a2-d462-4a05-8995-ac24989d66fa",
            "refuuid": "01e26aa4-db9d-4b1d-892d-d5e77b817b30",
            "name": "TUAMINOHEPTANE",
            "unii": "Z0420GYD84",
            "linking_id": "Z0420GYD84",
            "ref_pname": "TUAMINOHEPTANE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "31d84cdd-93a3-4605-8431-6a62a12a5439",
          "amount": {
            "uuid": "dc31b18e-c910-4111-83df-df541ff77740",
            "average": 5.4,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "interaction_type": "BINDING",
          "references": [
            "eb7283f9-1464-46ea-878e-f0115ee77add"
          ],
          "related_substance": {
            "uuid": "aad19cb3-7676-4181-a049-867620f9e3ef",
            "refuuid": "65eb0474-9c56-41df-9cc1-12932e1a7de4",
            "name": "PROTRIPTYLINE",
            "unii": "4NDU154T12",
            "linking_id": "4NDU154T12",
            "ref_pname": "PROTRIPTYLINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "3e272487-07ff-46bf-84c1-359bff57646b",
          "amount": {
            "uuid": "8d07daf7-337f-4991-9444-6e697f534af8"
          },
          "type": "INHIBITOR->TARGET",
          "related_substance": {
            "uuid": "eb8b40e8-d83d-4ba8-a0f7-7f780c15f32e",
            "refuuid": "79d40850-59f1-48ac-aad6-4e2737bbb0af",
            "name": "Clemeprol",
            "unii": "R3TC4SEW5A",
            "linking_id": "R3TC4SEW5A",
            "ref_pname": "Clemeprol",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "b140337c-c8bc-4a15-bd3b-3f72b3ea9aa5",
          "amount": {
            "uuid": "fa3a6658-e277-43fa-b03b-5e8b2ad6740c",
            "average": 420,
            "high": 560,
            "low": 280,
            "units": "NANOMOLAR"
          },
          "comments": "Transport affinity almost identical to norepinephrine.",
          "qualification": "IC50",
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "877a7aca-4cbc-49ed-a444-0b1ea76fe0e1"
          ],
          "related_substance": {
            "uuid": "be5bb610-151f-4c47-ae73-aa7bcdeb800a",
            "refuuid": "799d1e1c-c57f-42cf-93d2-23118127d1d6",
            "name": "AF-78 F-18",
            "unii": "Z8L8DWV2EK",
            "linking_id": "Z8L8DWV2EK",
            "ref_pname": "AF-78 F-18",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "3fa9cab2-53b2-4bda-b67a-ee1c01348440",
          "amount": {
            "uuid": "ad195f0a-eb9f-498c-afb9-0b74ef0cf638",
            "average": 117,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "references": [
            "a3858e50-0acd-43d9-af8d-87b8081bd063"
          ],
          "related_substance": {
            "uuid": "9f9c7bbd-e2f3-4e5e-99f2-fc0ec3087f37",
            "refuuid": "6c35f9c2-7ba4-488a-963f-aa8b8fc3f49e",
            "name": "6-APB",
            "unii": "285VE60914",
            "linking_id": "285VE60914",
            "ref_pname": "6-APB",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "cf34e8ec-3cdd-40bc-b686-e146ec892d27",
          "amount": {
            "uuid": "72a0ade9-3912-44af-aa1d-356cc319988b"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "639256b7-7032-4dc7-8627-7786282df4b9"
          ],
          "related_substance": {
            "uuid": "b0461a9b-8f83-45dd-bdb0-9367ae74b955",
            "refuuid": "4fe94e42-f1d1-4d3a-97a1-7dc930c965df",
            "name": "INDOPAN",
            "unii": "BIK35ACJ0Q",
            "linking_id": "BIK35ACJ0Q",
            "ref_pname": "INDOPAN",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "b1c84f78-21d4-44ab-834c-b5edb091b1c2",
          "amount": {
            "uuid": "f867b856-1394-4015-b4b0-983ff73483c0",
            "average": 2.1,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "interaction_type": "BINDING",
          "references": [
            "81f97001-7408-43f3-9fb8-f08e439b0665"
          ],
          "related_substance": {
            "uuid": "b9b1cbfe-1d5b-4942-a51d-b71ab770a578",
            "refuuid": "4b06cf2b-def5-4b99-83bf-ff8b6700434a",
            "name": "DESIPRAMINE",
            "unii": "TG537D343B",
            "linking_id": "TG537D343B",
            "ref_pname": "DESIPRAMINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "2f3b230e-5df3-491f-966a-686695eff3e8",
          "amount": {
            "uuid": "8cfc7ea1-709c-451c-b96b-d8ccdf7622ef",
            "average": 2.9,
            "units": "NANOMOLAR"
          },
          "qualification": "Kd",
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "36f9ac51-316d-4984-9034-6c47167952a9"
          ],
          "related_substance": {
            "uuid": "68dda05b-fffc-4f2f-9f84-cac32496e9c3",
            "refuuid": "ef751596-fb1d-49e3-b433-72e530b8981d",
            "name": "Nisoxetine H-3",
            "unii": "3RHE5Z6TXP",
            "linking_id": "3RHE5Z6TXP",
            "ref_pname": "Nisoxetine H-3",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "c5e83df5-4e72-4dd1-a991-26160ccd3553",
          "amount": {
            "uuid": "49cdd829-3e9d-4cd2-8653-eb04a73785b6"
          },
          "type": "RADIOLIGAND->TARGET",
          "references": [
            "c2725ed5-076c-4604-9fc4-0fb602f2fed6"
          ],
          "related_substance": {
            "uuid": "b2d24ad7-e8e0-404e-8dd2-763fa9626107",
            "refuuid": "e71a5296-5c7e-4a42-8ca5-69390ee0b86d",
            "name": "4F-MHPG F-18",
            "unii": "3BPF2MD5QE",
            "linking_id": "3BPF2MD5QE",
            "ref_pname": "4F-MHPG F-18",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "9b0e88da-335d-4b05-bc7e-4a023af1fe48",
          "amount": {
            "uuid": "4d2c2b80-d4f0-43c1-956d-1329e05c8ce0",
            "average": 200,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "INHIBITOR->TARGET",
          "interaction_type": "BINDING",
          "references": [
            "45f8ea3a-d344-4158-9439-0e3026230b22"
          ],
          "related_substance": {
            "uuid": "79aa3e1f-dc65-43e1-8de9-12e5e6474140",
            "refuuid": "c501493a-fa00-4d2e-a299-fcba4e4e02f5",
            "name": "VANOXERINE",
            "unii": "90X28IKH43",
            "linking_id": "90X28IKH43",
            "ref_pname": "VANOXERINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "2ba49bf6-0d10-4743-85b3-72f745333f85",
          "amount": {
            "uuid": "29f4f6e9-31d7-47ca-8c92-adcc3ffd7273"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "04c676d8-6632-480d-a54b-b6485f6c930c"
          ],
          "related_substance": {
            "uuid": "ab45495e-54c7-423e-9474-926e2d5a2f79",
            "refuuid": "062e75f2-b72d-4e09-8608-c41105b96bff",
            "name": "DESVENLAFAXINE, (-)-",
            "unii": "HY5T9WKI4O",
            "linking_id": "HY5T9WKI4O",
            "ref_pname": "DESVENLAFAXINE, (-)-",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "7ac449e0-fe10-4c26-88e0-b70bf35314e0",
          "amount": {
            "uuid": "18ce114a-b73d-4ee6-b632-fa0942882b66",
            "average": 531.3,
            "high": 644.3,
            "low": 418.3,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "WEAK INHIBITOR->TARGET",
          "references": [
            "0c69182a-3033-4eb4-ad4f-0a08c5ce17ee"
          ],
          "related_substance": {
            "uuid": "536a404c-bb62-46a0-9620-b2cb58b7f9d3",
            "refuuid": "eb2e8a38-528a-4b49-9dba-f7af328d3996",
            "name": "DESVENLAFAXINE",
            "unii": "NG99554ANW",
            "linking_id": "NG99554ANW",
            "ref_pname": "DESVENLAFAXINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "bd5435c3-71e9-4bcc-8766-cf87dfc0c4f3",
          "amount": {
            "uuid": "ff7fa702-e866-41b8-a97c-db9d6b20b336"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "5ebfb786-79c7-4ab1-81bd-6d08adafe15c"
          ],
          "related_substance": {
            "uuid": "58e41934-7505-4015-a0f5-c66eaa9b10b4",
            "refuuid": "9f570f75-a598-42d3-bc95-9fa5c6346322",
            "name": "PSN-602",
            "unii": "B27VXE4GHR",
            "linking_id": "B27VXE4GHR",
            "ref_pname": "PSN-602",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "e57160f4-8cb6-4042-90f6-616a9aa51c9d",
          "amount": {
            "uuid": "c67b42b5-d3e9-4973-9bfe-24661b7c31ce",
            "average": 118,
            "units": "NANOMOLAR"
          },
          "qualification": "Ki",
          "type": "INHIBITOR->TARGET",
          "references": [
            "a2813725-7394-447f-b9e1-0de1372ad134"
          ],
          "related_substance": {
            "uuid": "b3212a58-52ec-4494-b6f2-027e1135eb98",
            "refuuid": "8037c5dc-2eea-4de4-b955-4c3c38c6deff",
            "name": "Vortioxetine",
            "unii": "3O2K1S3WQV",
            "linking_id": "3O2K1S3WQV",
            "ref_pname": "Vortioxetine",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "a56525ed-3cc1-4d25-9a14-b8e749a399d8",
          "amount": {
            "uuid": "ae66f2d3-6f4e-487d-9360-e0bd5b86e095",
            "average": 72,
            "high": 93,
            "low": 51,
            "units": "NANOMOLAR"
          },
          "qualification": "IC50",
          "type": "WEAK INHIBITOR->TARGET",
          "references": [
            "a7c4085e-5ebd-4aba-861f-fd58e9cdfa6c"
          ],
          "related_substance": {
            "uuid": "996f3932-383b-44a5-9e7c-e18adf28e902",
            "refuuid": "705c5821-34b5-4933-ae24-86e7efbe23dc",
            "name": "Pudafensine",
            "unii": "L9NG7US8GE",
            "linking_id": "L9NG7US8GE",
            "ref_pname": "Pudafensine",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "173900d7-fc00-4e2c-82f9-4046037eb8b3",
          "amount": {
            "uuid": "6ce05666-75ae-4935-b8e7-85089ca523ec"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "a56efa5b-08c8-4f5a-85b3-f0305b7e0422"
          ],
          "related_substance": {
            "uuid": "e84b7559-38e5-442a-8b47-2d37c7b22310",
            "refuuid": "abd095af-8412-4c88-bc37-f3d1b5546297",
            "name": "Ro-035939 free base",
            "unii": "Q362RQ92NG",
            "linking_id": "Q362RQ92NG",
            "ref_pname": "Ro-035939 free base",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "ffbb9dab-bb73-4f0f-be8f-793d6cceac64",
          "amount": {
            "uuid": "c06e160c-89fb-4105-820b-82a0ca5b492e"
          },
          "type": "INHIBITOR->TARGET",
          "references": [
            "a23c66aa-b9eb-41c4-8ae6-0e32b60ca70c"
          ],
          "related_substance": {
            "uuid": "d9d09819-01b8-4ff7-a0cf-3a31645259cc",
            "refuuid": "0aa12195-b070-405b-bcae-0174c9c61fec",
            "name": "EXP-561",
            "unii": "1P958G9T1V",
            "linking_id": "1P958G9T1V",
            "ref_pname": "EXP-561",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "0612fcf5-05db-4d89-9fb5-58a4b284a72c",
          "amount": {
            "uuid": "93aa6e0f-cd85-49c6-bdc5-4a25e5633027",
            "average": 19.3,
            "high": 27.56,
            "low": 11.04,
            "units": "MICROMOLAR"
          },
          "qualification": "IC50",
          "type": "WEAK INHIBITOR->OFF TARGET",
          "references": [
            "97343f90-b7bd-404a-8c61-0256a6340f3f"
          ],
          "related_substance": {
            "uuid": "6cdcd559-4653-4ece-9927-2e20b4c41f60",
            "refuuid": "ae714a7d-2ed8-459e-b776-7f6c6db4afe7",
            "name": "MIDOMAFETAMINE, (R)-",
            "unii": "3947754WXW",
            "linking_id": "3947754WXW",
            "ref_pname": "MIDOMAFETAMINE, (R)-",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "protein",
      "names": [
        {
          "uuid": "eec89701-6537-f129-e7f3-58190907c3e7",
          "name": "NAT1",
          "stdName": "NAT1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "c340865e-5d4b-a779-f5e6-d034a81d9ee5",
          "name": "NET",
          "stdName": "NET",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "a6eb7183-dddf-f47c-5466-c8c067d7a151",
          "name": "NET1",
          "stdName": "NET1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "57676c25-10d6-483e-1e38-eea2293f9d2a",
          "name": "NOREPINEPHRINE TRANSPORTER",
          "stdName": "NOREPINEPHRINE TRANSPORTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "f8823651-ef85-4b44-8d78-43a6b43b9524",
          "name": "SLC6A2",
          "stdName": "SLC6A2",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "be48e46d-1644-d5f2-7a90-6c3c67033857",
          "name": "SLC6A5",
          "stdName": "SLC6A5",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        },
        {
          "uuid": "ddaff481-b43c-7043-d1cc-136169f8758d",
          "name": "SODIUM-DEPENDENT NORADRENALINE TRANSPORTER",
          "stdName": "SODIUM-DEPENDENT NORADRENALINE TRANSPORTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": true
        },
        {
          "uuid": "dd06c8fb-c664-4ddd-85da-8656159e4022",
          "name": "SOLUTE CARRIER FAMILY 6 MEMBER 2",
          "stdName": "SOLUTE CARRIER FAMILY 6 MEMBER 2",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "660a63e5-9f50-4fd7-9742-e02d5e289109",
          "citation": "https://www.jpain.org/article/S1526-5900(11)00268-9/abstract",
          "doc_type": "MEETING ABSTRACT",
          "public_domain": true
        },
        {
          "uuid": "d450edd1-0b4e-d1e2-3f35-9f798e5b4278",
          "citation": "208447Orig1s000 MULTI-DISCIPLINE REVIEW",
          "url": "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2017/208447Orig1s000MultidisciplineR.pdf",
          "doc_type": "NDA PUBLIC REVIEW",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "0b2f3a25-2117-1940-0dc0-db83f7509e2c",
          "citation": "P23975",
          "url": "http://www.uniprot.org/uniprot/P23975",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "0aef3b48-6458-d48f-e303-6811e1a4e19e",
          "citation": "Norepinephrine transporter",
          "url": "https://en.wikipedia.org/wiki/Norepinephrine_transporter",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "19546650-86a5-4d37-a76f-832e76631e01",
          "citation": "Tamagnan, Gilles D., et al. \"Development of SPECT imaging agents for the norepinephrine transporters:[123I] INER.\" Bioorganic & medicinal chemistry letters 17.2 (2007): 533-537.",
          "url": "https://www.sciencedirect.com/science/article/pii/S0960894X06011802",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "fed3b02b-977e-4d7c-88cb-5a5e9d647443",
          "citation": "López‐Arnau, Raul, et al. \"Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone.\" British journal of pharmacology 167.2 (2012): 407-420.",
          "url": "https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1476-5381.2012.01998.x?casa_token=n1zW1gg9eEUAAAAA:q-0lh9YnUi-FqwSabNjdAE3GXYop9WhtNvU0aOcPseL3hFXAIYHdFQpqjP2KBBOMdsqU9mbSIkuNdYk",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "bb8b3e68-77f0-4937-baa7-311a7df6370a",
          "citation": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C82344",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C82344",
          "doc_type": "NCI THESAURUS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "266c02ba-6983-4a11-8ad7-628fc2f7701f",
          "citation": "Grond, Stefan, and Armin Sablotzki. \"Clinical pharmacology of tramadol.\" Clinical pharmacokinetics 43.13 (2004): 879-923.",
          "url": "https://link.springer.com/article/10.2165/00003088-200443130-00004",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "2cccdcb6-c122-43e9-a500-d7a9612b6f06",
          "citation": "MANUFACTURER",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE",
            "NOMEN"
          ]
        },
        {
          "uuid": "1b0e39dc-f2cf-4f8e-a8de-ce9359e25803",
          "citation": "PUBCHEM",
          "doc_type": "PUBCHEM",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f9c97c23-172c-48c3-90fe-b897b100b45b",
          "citation": "Grond, Stefan, and Armin Sablotzki. \"Clinical pharmacology of tramadol.\" Clinical pharmacokinetics 43.13 (2004): 879-923.",
          "url": "https://link.springer.com/article/10.2165/00003088-200443130-00004",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "fcca8f1d-1fe9-471d-a7be-568a21e857c5",
          "citation": "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/211230Orig1Orig2s000PharmR.pdf",
          "doc_type": "NDA PUBLIC REVIEW",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "35562b51-e4e7-43e1-a303-360625b34130",
          "citation": "https://www.phrma.org/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/PDF/MID_Mental-Illness-2019-Drug-List_FINAL.pdf",
          "doc_type": "WEB PAGE",
          "public_domain": true
        },
        {
          "uuid": "676f70e3-9171-44ba-a8fa-1ef70c50eabb",
          "citation": "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/211230Orig1Orig2s000PharmR.pdf",
          "doc_type": "NDA PUBLIC REVIEW",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "37bbea26-e349-4df2-b37b-ee62b49c5f04",
          "citation": "Grond, Stefan, and Armin Sablotzki. \"Clinical pharmacology of tramadol.\" Clinical pharmacokinetics 43.13 (2004): 879-923.",
          "url": "https://link.springer.com/article/10.2165/00003088-200443130-00004",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "c95a9f6f-bb81-40d6-b353-37df88880baa",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "1ec9db76-e10b-41bb-ab34-9add1f9a0429",
          "citation": "Jensen, Niels H., et al. \"N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT 1A agonist, as a putative mediator of quetiapine's antidepressant activity.\" Neuropsychopharmacology 33.10 (2008): 2303-2312.",
          "url": "https://www.nature.com/articles/1301646",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "10ea0204-35ce-4edd-a2e6-565428d74907",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "e114b330-e8ce-41e7-b48e-3cbaaaa3ee0e",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "0083b226-3b4b-4f42-8c2e-0bb4c380b32f",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "68eb8857-12f9-426f-9360-3b6c9838a587",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "32003b56-6bd2-481a-a227-bf6aacd769f2",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "18da98da-23cd-4ba7-8b64-eff21cc3e98c",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "f26c0bc3-a2e3-4d22-b40b-cb50788f8100",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "11020326-c32b-4b81-a76e-1b4fc0221616",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "7f7e69dc-ac59-4710-8514-98f949ae1ed3",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "be88c0be-a665-4073-a4d7-75eb300d1c4b",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "af580592-14be-4a0c-abeb-9b80bb7bbe03",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "da66c5f5-94f0-4c94-9eae-5ce3aa5369f7",
          "citation": "https://clinicaltrials.gov/ct2/show/NCT03207464",
          "url": "https://clinicaltrials.gov/ct2/show/NCT03207464",
          "doc_type": "CLINICALTRIALS",
          "public_domain": true
        },
        {
          "uuid": "5539ae9a-0563-4de8-8b18-c2e858634afd",
          "citation": "SEND TO\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\n\\\\nJ LABELLED COMP RADIOPHARM. 2013 MAY 15;56(5):307-9. DOI: 10.1002/JLCR.3047. EPUB 2013 APR 24.",
          "url": "http://www.ncbi.nlm.nih.gov/pubmed/24285377",
          "doc_type": "JOURNAL ARTICLE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d318d14a-a871-4a69-960b-76d125510c0f",
          "citation": "https://en.wikipedia.org/wiki/Diphenylprolinol",
          "url": "https://en.wikipedia.org/wiki/Diphenylprolinol",
          "doc_type": "WIKI",
          "public_domain": true
        },
        {
          "uuid": "94f42d79-6e57-4fe6-a9d6-7350204c63ea",
          "citation": "Goud, Nerella Sridhar, et al. \"Carbon-11: radiochemistry and target-based pet molecular imaging applications in oncology, cardiology, and neurology.\" Journal of Medicinal Chemistry 64.3 (2021): 1223-1259.",
          "url": "https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01053",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "8ec5afb3-574b-4c70-8b37-fa2bd45f007f",
          "citation": "Shibao, Cyndya A., et al. \"Predictors of the pressor response to the norepinephrine transporter inhibitor, atomoxetine, in neurogenic orthostatic hypotension.\" Hypertension 78.2 (2021): 525-531.",
          "url": "https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.119.14483",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "735a26e6-bb52-407f-ba0a-f068a6d49c67",
          "citation": "Goud, Nerella Sridhar, et al. \"Carbon-11: radiochemistry and target-based pet molecular imaging applications in oncology, cardiology, and neurology.\" Journal of Medicinal Chemistry 64.3 (2021): 1223-1259.",
          "url": "https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01053",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "c90e0530-3c5e-438a-8485-8a411f70063a",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a5f24767-7859-4a07-bb5e-35b1bb242e21",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "1c344cb1-0ce2-4521-9e2f-55a4262db9fe",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "c747d1ee-9173-48f7-8325-3c65e6ef5748",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "e5cd8a3a-2c55-4588-af72-d358b7a7133b",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a2c15105-1b1c-4ae0-905e-7071ed6137b5",
          "citation": "Ehsanullah, Raihana SB, et al. \"Clinical pharmacological studies of tandamine, a potential antidepressive drug.\" Psychopharmacology 52.1 (1977): 73-77.",
          "url": "https://link.springer.com/content/pdf/10.1007/BF00426603.pdf",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "f52ff1e1-335c-484d-bc2a-3036b181a00f",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "7a909ecf-c74a-4f78-b98e-30144c527db4",
          "citation": "Iversen, Les, et al. \"Neurochemical profiles of some novel psychoactive substances.\" European journal of pharmacology 700.1-3 (2013): 147-151.",
          "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582025/",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "a152c30c-9686-44b4-969d-4583fc3b2ea2",
          "citation": "Kolaczynska, Karolina E., et al. \"Pharmacological characterization of 3, 4-methylenedioxamphetamine (MDA) analogs and two amphetamine-based compounds: N, α-DEPEA and DPIA.\" European Neuropsychopharmacology 59 (2022): 9-22.",
          "url": "https://www.sciencedirect.com/science/article/pii/S0924977X22001560",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a3858e50-0acd-43d9-af8d-87b8081bd063",
          "citation": "Iversen, Les, et al. \"Neurochemical profiles of some novel psychoactive substances.\" European journal of pharmacology 700.1-3 (2013): 147-151.",
          "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582025/",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "dc1f9a7b-a03b-4aac-8d8e-4642b091ec6d",
          "citation": "WIK",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "639256b7-7032-4dc7-8627-7786282df4b9",
          "citation": "Nagai, Fumiko, Ryouichi Nonaka, and Kanako Satoh Hisashi Kamimura. \"The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.\" European journal of pharmacology 559.2-3 (2007): 132-137.",
          "url": "https://www.sciencedirect.com/science/article/pii/S0014299906013811",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "eb7283f9-1464-46ea-878e-f0115ee77add",
          "citation": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "url": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "doc_type": "ASSAY REFERENCE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "d2a242bb-8538-4666-a2bb-1acecac3dc88",
          "citation": "Schlessinger, Avner, et al. \"Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.\" Proceedings of the National Academy of Sciences 108.38 (2011): 15810-15815.",
          "url": "file:///C:/Users/CALLAHANL/Downloads/schlessinger-et-al-2011-structure-based-discovery-of-prescription-drugs-that-interact-with-the-norepinephrine.pdf",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "a7c4085e-5ebd-4aba-861f-fd58e9cdfa6c",
          "citation": "Comerma‐Steffensen, Simon, et al. \"A novel reuptake inhibitor, IP2015, induces erection by increasing central dopamine and peripheral nitric oxide release.\" British Journal of Pharmacology (2024).",
          "url": "https://bpspubs.onlinelibrary.wiley.com/doi/epdf/10.1111/bph.16362",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "06cdeda4-7a57-471c-b94f-6c8c7dd58f20",
          "citation": "Bolnot-Delmas, Dominique, et al. \"Ro 15-8081 in osteoarthritis of hip and knee: a double-blind placebo-controlled multicentre dose-ranging study on analgesia.\" Pain 64.1 (1996): 99-105.",
          "url": "https://www.sciencedirect.com/science/article/pii/0304395995000755",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "a56efa5b-08c8-4f5a-85b3-f0305b7e0422",
          "citation": "Polc, P., J. Schneeberger, and W. Haefely. \"Effects of several centrally active drugs on the sleep-wakefulness cycle of cats.\" Neuropharmacology 18.3 (1979): 259-267.",
          "url": "https://www.sciencedirect.com/science/article/pii/0028390879901242",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "36f9ac51-316d-4984-9034-6c47167952a9",
          "citation": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "url": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "doc_type": "ASSAY REFERENCE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "dca4f38e-7592-47e3-8db5-d9d871baf30c",
          "citation": "https://www.drugbank.ca/drugs/DB00458",
          "doc_type": "WEB PAGE",
          "public_domain": true
        },
        {
          "uuid": "45f8ea3a-d344-4158-9439-0e3026230b22",
          "citation": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "url": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "doc_type": "ASSAY REFERENCE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "c2725ed5-076c-4604-9fc4-0fb602f2fed6",
          "citation": "Chen, Xinyu, et al. \"Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements.\" Journal of Neural Transmission 127.6 (2020): 851-873.",
          "url": "https://link.springer.com/article/10.1007/s00702-020-02180-4",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "81f97001-7408-43f3-9fb8-f08e439b0665",
          "citation": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "url": "https://www.eurofinsdiscovery.com/catalogmanagement/viewItem/355",
          "doc_type": "ASSAY REFERENCE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a23c66aa-b9eb-41c4-8ae6-0e32b60ca70c",
          "citation": "Maj, J., et al. \"Pharmacological properties of EXP 561, a potential antidepressant drug.\" Journal of neural transmission 70 (1987): 81-97.",
          "url": "https://link.springer.com/content/pdf/10.1007/BF01252511.pdf",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "97343f90-b7bd-404a-8c61-0256a6340f3f",
          "citation": "Verrico, Christopher D., Gregory M. Miller, and Bertha K. Madras. \"MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment.\" Psychopharmacology 189 (2007): 489-503.",
          "url": "https://link.springer.com/article/10.1007/s00213-005-0174-5",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "5ebfb786-79c7-4ab1-81bd-6d08adafe15c",
          "citation": "https://www.technologynetworks.com/drug-discovery/news/osi-pharmaceuticals-initiates-clinical-development-program-for-antiobesity-candidate-psn602-204555",
          "url": "https://www.technologynetworks.com/drug-discovery/news/osi-pharmaceuticals-initiates-clinical-development-program-for-antiobesity-candidate-psn602-204555",
          "doc_type": "WEB PAGE",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "a2813725-7394-447f-b9e1-0de1372ad134",
          "citation": "Bang-Andersen, Benny, et al. \"Discovery of 1-[2-(2, 4-dimethylphenylsulfanyl) phenyl] piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.\" Journal of medicinal chemistry 54.9 (2011): 3206-3221.",
          "url": "https://pubs.acs.org/doi/full/10.1021/jm101459g",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "877a7aca-4cbc-49ed-a444-0b1ea76fe0e1",
          "citation": "Chen, Xinyu, et al. \"Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity—Introducing High NET Affinity PET Probe 18F-AF78.\" Theranostics 12.9 (2022): 4446.",
          "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169360/",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "129d868d-8ce5-4ac7-a69f-d07e1a093227",
          "citation": "Sinusas, Albert J., et al. \"Biodistribution and radiation dosimetry of LMI1195: first-in-human study of a novel 18F-labeled tracer for imaging myocardial innervation.\" J Nucl Med 55.9 (2014): 1445-51.",
          "url": "http://jnm.snmjournals.org/content/55/9/1445",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "04c676d8-6632-480d-a54b-b6485f6c930c",
          "citation": "Mandrioli, Roberto, and Laura Mercolini. \"Discontinued anxiolytic drugs (2009–2014).\" Expert opinion on investigational drugs 24.4 (2015): 557-573.",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "0c69182a-3033-4eb4-ad4f-0a08c5ce17ee",
          "citation": "Deecher, Darlene C., et al. \"Desvenlafaxine succinate: a new serotonin and norepinephrine reuptake inhibitor.\" Journal of pharmacology and experimental therapeutics 318.2 (2006): 657-665.",
          "url": "https://jpet.aspetjournals.org/content/jpet/318/2/657.full.pdf",
          "doc_type": "JA",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "protein": {
        "uuid": "14308367-6fde-4523-b861-3dc878fe071c",
        "glycosylation": {
          "uuid": "26a678a6-ea7a-4e3d-b91e-6d3b2e74deb9",
          "glycosylation_type": "HUMAN",
          "n_glycosylation_sites": [
            {
              "residue_index": 184,
              "subunit_index": 1
            },
            {
              "residue_index": 192,
              "subunit_index": 1
            },
            {
              "residue_index": 198,
              "subunit_index": 1
            }
          ]
        },
        "subunits": [
          {
            "uuid": "2d3ced65-59e6-49b5-a69e-c0648c15727c",
            "sequence": "MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQRDIRQFQLQHWLAI",
            "subunit_index": 1
          }
        ],
        "references": [
          "0b2f3a25-2117-1940-0dc0-db83f7509e2c"
        ],
        "disulfide_links": [
          {
            "sites": [
              {
                "residue_index": 176,
                "subunit_index": 1
              },
              {
                "residue_index": 185,
                "subunit_index": 1
              }
            ]
          }
        ],
        "protein_sub_type": "",
        "protein_type": "TRANSPORTER",
        "sequence_origin": "HUMAN",
        "sequence_type": "COMPLETE"
      },
      "definition_level": "COMPLETE",
      "uuid": "0984671c-0dd0-410d-b763-0a7c9195929d",
      "version": "82",
      "properties": [
        {
          "uuid": "0412b659-80ab-4d74-9fae-d61b7f85813d",
          "name": "MOL_WEIGHT:NUMBER(CALCULATED)",
          "type": "amount",
          "value": {
            "uuid": "cba5a1e9-529a-4467-8f12-9286725ae518",
            "type": "ESTIMATED",
            "average": 69300,
            "units": "Da"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "unii": "HN86OLH1NW"
    }
  ]
}