{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "f0fcc6e2-7a15-4c7c-ad7f-3a40507152ba",
          "code": "106096-92-8",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=106096-92-8",
          "code_system": "CAS",
          "references": [
            "9109b971-5d74-4cc0-a243-e2d23d453a78",
            "0d0c66d2-e051-40cc-831b-c6ffc0c24189"
          ]
        },
        {
          "uuid": "25f710ee-3f67-4558-8a26-17be5b7b4e16",
          "code": "62031-54-3",
          "type": "GENERIC (FAMILY)",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=62031-54-3",
          "code_system": "CAS",
          "references": [
            "9109b971-5d74-4cc0-a243-e2d23d453a78",
            "7a1da155-cc26-43af-8f78-24063178f972"
          ]
        },
        {
          "uuid": "ab87f013-0267-447a-92ac-b4674303a392",
          "code": "1591916",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/1591916/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "9109b971-5d74-4cc0-a243-e2d23d453a78"
          ]
        },
        {
          "uuid": "3a47dae2-d9d6-43f0-9981-87f89da67709",
          "code": "m5371",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m5371?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "9109b971-5d74-4cc0-a243-e2d23d453a78"
          ]
        },
        {
          "uuid": "24ee5cda-cf99-ad29-277e-8e462045bc3c",
          "code": "DB05599",
          "type": "PRIMARY",
          "url": "https://go.drugbank.com/drugs/DB05599",
          "code_system": "DRUG BANK",
          "references": [
            "6c9d28b2-a148-57fb-1de0-139f1a9a53b2"
          ]
        },
        {
          "uuid": "33375778-b9c0-46a7-bfe7-d7ee1369b7ef",
          "code": "G53298VN9Y",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "c57021a9-4234-a22e-6d13-e1cbf5989ab1",
          "code": "G53298VN9Y",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=G53298VN9Y",
          "code_system": "DAILYMED",
          "references": [
            "f1fe3996-e402-d857-694d-de76baf9a17d"
          ]
        }
      ],
      "substance_class": "protein",
      "references": [
        {
          "uuid": "d069f440-5352-4f90-921a-ce350ba35c42",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "a76d15a3-eda6-4a77-ae86-4a1949f24fa0",
          "citation": "BIMS migrated",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c5b20839-9067-4b86-8dbb-432b9601db0a",
          "citation": "UNIPROT",
          "doc_type": "UNIPROT",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ec4fed9d-1983-4f86-8d05-97d44b84e748",
          "citation": "UNIPROT",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3a7b2d22-d617-411c-8597-1fce7df1a824",
          "citation": "PCPC-DB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "f1e21993-939b-4146-abff-d66c3e358eed",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9109b971-5d74-4cc0-a243-e2d23d453a78",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493392435000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e0fb45e3-0b8d-40de-91f1-91aaf6f27533",
          "citation": "SRS import [G53298VN9Y]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=G53298VN9Y",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493392435000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "058c9111-3aca-4ee6-909d-1bc2890d14cb",
          "citation": "SH-POLYPEPTIDE-11 [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b0365a80-bd25-42dc-8574-0c9868cccbba",
          "citation": "RH-POLYPEPTIDE-11 [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "420bf259-1fa0-4fa4-9b83-eab4738693c1",
          "citation": "ACIDIC FIBROBLAST GROWTH FACTOR [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "0d0c66d2-e051-40cc-831b-c6ffc0c24189",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "7a1da155-cc26-43af-8f78-24063178f972",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "ae178b50-1165-4cf2-a807-16a1dcd087d8",
          "citation": "NCI DRUG DICTIONARY",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "38c64aa1-160a-4db5-c27b-1627ee8b5a85",
          "citation": "WHO DRUG DICTIONARY 2019",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "b79a4293-61d8-4706-b283-b5c3349f5419",
          "citation": "TA-46 Mechanism Of Action",
          "url": "https://www.beyondachondroplasia.org/en/health/treatments/emergent-treatments/84-ta-46-mechanism-of-action",
          "doc_type": "WEB PAGE",
          "public_domain": true
        },
        {
          "uuid": "6c9d28b2-a148-57fb-1de0-139f1a9a53b2",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "e3c40d77-14ef-46bc-b1e8-a6746e72895f",
          "citation": "TA-46 Mechanism Of Action",
          "url": "https://www.beyondachondroplasia.org/en/health/treatments/emergent-treatments/84-ta-46-mechanism-of-action",
          "doc_type": "WEB PAGE",
          "public_domain": true
        },
        {
          "uuid": "f1fe3996-e402-d857-694d-de76baf9a17d",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "b5ef96c6-e43d-dc98-9a1c-0d889d405fef",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "9226afa5-16a3-49f4-8f42-0746aa054291",
      "version": "18",
      "unii": "G53298VN9Y",
      "relationships": [
        {
          "uuid": "ec94271a-cd51-4486-b733-fa255708d057",
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "64a29add-834e-44e0-95d7-e865eb95c358",
            "refuuid": "9226afa5-16a3-49f4-8f42-0746aa054291",
            "name": "FIBROBLAST GROWTH FACTOR-1",
            "unii": "G53298VN9Y",
            "linking_id": "G53298VN9Y",
            "ref_pname": "FIBROBLAST GROWTH FACTOR-1",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "5873507e-8bc2-4ade-b576-bfd12a096b19",
          "amount": {
            "uuid": "9535493c-748b-4b22-9f76-16051c3d11ba"
          },
          "comments": "Prevents FGFR ligands, such as FGF1, FGF2, FGF4, from binding to their cognate receptors, thereby inhibiting the activation of the related FGFR tyrosine kinases. Inhibition of FGFR1 by this agent may retard tumor cell proliferation and induce tumor cell death. FP-1039 may also inhibit vascular endothelial growth factor (VEGF)-induced angiogenesis. FGFR1 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cellular proliferation, differentiation, angiogenesis, and survival; most ligands that bind to FGFR1 also bind to the related receptors FGFR3 and FGFR4.",
          "type": "INHIBITOR->TARGET",
          "references": [
            "ae178b50-1165-4cf2-a807-16a1dcd087d8"
          ],
          "related_substance": {
            "uuid": "d08d26fb-d357-4eea-b5c6-feae053cfc9b",
            "refuuid": "0308ece2-8e15-41cd-b92a-e8bf51452346",
            "name": "FP-1039",
            "unii": "CTG26PRE5S",
            "linking_id": "CTG26PRE5S",
            "ref_pname": "FP-1039"
          }
        },
        {
          "uuid": "fcb8bdef-fca6-445e-895b-d576b00384a1",
          "amount": {
            "uuid": "0f26a385-2ab1-453f-8648-a0e8ebe0654a"
          },
          "type": "LIGAND->TARGET",
          "references": [
            "e3c40d77-14ef-46bc-b1e8-a6746e72895f"
          ],
          "related_substance": {
            "uuid": "2e1a12e4-2649-4e08-88e1-39b908dac4e2",
            "refuuid": "ee203cde-eadd-4a3a-9164-f2c9ab630668",
            "name": "RECIFERCEPT",
            "unii": "620C079F3I",
            "linking_id": "620C079F3I",
            "ref_pname": "RECIFERCEPT"
          }
        }
      ],
      "names": [
        {
          "uuid": "0a8aa75a-7c53-4bf9-a720-4ab5ca6861e9",
          "name": "ACIDIC FIBROBLAST GROWTH FACTOR",
          "stdName": "ACIDIC FIBROBLAST GROWTH FACTOR",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "420bf259-1fa0-4fa4-9b83-eab4738693c1",
            "f1e21993-939b-4146-abff-d66c3e358eed",
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "3a50c25c-9d5c-4aca-9c41-4046a1285f54",
          "name": "ACIDIC FIBROBLAST GROWTH FACTOR [MI]",
          "stdName": "ACIDIC FIBROBLAST GROWTH FACTOR [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f1e21993-939b-4146-abff-d66c3e358eed",
            "c5b20839-9067-4b86-8dbb-432b9601db0a"
          ],
          "display_name": false
        },
        {
          "uuid": "eac0d896-8f85-464f-8ab7-216c11e92cec",
          "name": "AFGF",
          "stdName": "AFGF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "a54345bc-6f67-a02c-5c7c-e916eed2a4d3",
          "name": "Acidic fibroblast growth factor [WHO-DD]",
          "stdName": "ACIDIC FIBROBLAST GROWTH FACTOR [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "b5ef96c6-e43d-dc98-9a1c-0d889d405fef"
          ],
          "display_name": false
        },
        {
          "uuid": "b71db856-72df-42c5-a8d5-b2d71792ff60",
          "name": "BF-FIBROBLAST GROWTH FACTOR",
          "stdName": "BF-FIBROBLAST GROWTH FACTOR",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false
        },
        {
          "uuid": "fbae2e3f-ecdc-4dc9-b964-8f2a69b1c34c",
          "name": "BIO-FD&C AFGF",
          "stdName": "BIO-FD&C AFGF",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false
        },
        {
          "uuid": "2f0653a9-4481-404f-a787-bd3ade4e9d8b",
          "name": "ECGF",
          "stdName": "ECGF",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "129a6723-7ed9-4995-b90e-599a577b4253",
          "name": "ENDOTHELIAL CELL GROWTH FACTOR",
          "stdName": "ENDOTHELIAL CELL GROWTH FACTOR",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "cfab13ee-b8bb-4ee8-a8d1-57acc22a9d51",
          "name": "FGF-1",
          "stdName": "FGF-1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "f8e0e34e-2094-cff7-6f0c-f4bc7a410816",
          "name": "FGF1",
          "stdName": "FGF1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d069f440-5352-4f90-921a-ce350ba35c42"
          ],
          "display_name": false
        },
        {
          "uuid": "26feab73-ac9f-47e9-b684-f705471beae5",
          "name": "FIBROBLAST GROWTH FACTOR 1",
          "stdName": "FIBROBLAST GROWTH FACTOR 1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "43d4ec76-691f-492d-af49-2e27e497f78d",
          "name": "FIBROBLAST GROWTH FACTOR 1 (HUMAN)",
          "stdName": "FIBROBLAST GROWTH FACTOR 1 (HUMAN)",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "d069f440-5352-4f90-921a-ce350ba35c42"
          ],
          "display_name": false
        },
        {
          "uuid": "0ac3a47f-c89d-47da-962f-75f873e43351",
          "name": "FIBROBLAST GROWTH FACTOR-1",
          "stdName": "FIBROBLAST GROWTH FACTOR-1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a76d15a3-eda6-4a77-ae86-4a1949f24fa0",
            "d069f440-5352-4f90-921a-ce350ba35c42"
          ],
          "display_name": true
        },
        {
          "uuid": "438c71d8-8d87-4153-9900-bbf946769654",
          "name": "HBGF-1",
          "stdName": "HBGF-1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "830ced91-67bd-4ed9-9fe9-bd2de0ef7513",
          "name": "HEPARIN-BINDING GROWTH FACTOR 1",
          "stdName": "HEPARIN-BINDING GROWTH FACTOR 1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "ec4fed9d-1983-4f86-8d05-97d44b84e748"
          ],
          "display_name": false
        },
        {
          "uuid": "f3a53ae3-ed43-4d33-9761-fda723c293ce",
          "name": "HUMAN FIBROBLAST GROWTH FACTOR 1",
          "stdName": "HUMAN FIBROBLAST GROWTH FACTOR 1",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "d069f440-5352-4f90-921a-ce350ba35c42"
          ],
          "display_name": false
        },
        {
          "uuid": "4771704c-c511-45d9-8b77-6e4bb3f60386",
          "name": "HUMAN OLIGOPEPTIDE-13",
          "stdName": "HUMAN OLIGOPEPTIDE-13",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false
        },
        {
          "uuid": "82a4b3ee-b0e9-49ba-8035-892693a54bf9",
          "name": "NEXPURE BIO AFGF",
          "stdName": "NEXPURE BIO AFGF",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false
        },
        {
          "uuid": "840b3272-2ff4-419f-9da1-33ccf4911964",
          "name": "RH-POLYPEPTIDE-11",
          "stdName": "RH-POLYPEPTIDE-11",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": true,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824",
            "b0365a80-bd25-42dc-8574-0c9868cccbba"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "d5078be1-46d0-4ecb-9f0e-30f51d3d8bab",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "d8460b8a-d36f-4445-91be-bd860094dd3e",
          "name": "SH-POLYPEPTIDE-11",
          "stdName": "SH-POLYPEPTIDE-11",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": true,
          "references": [
            "058c9111-3aca-4ee6-909d-1bc2890d14cb",
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "ff2a79b7-fcb3-49db-9cda-52e678c3fa21",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "e5a014a3-ede2-4408-bd5b-7783fa7060fc",
          "name": "VEXXON-AFGF",
          "stdName": "VEXXON-AFGF",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "c5b20839-9067-4b86-8dbb-432b9601db0a",
            "3a7b2d22-d617-411c-8597-1fce7df1a824"
          ],
          "display_name": false
        }
      ],
      "protein": {
        "uuid": "01458707-8aed-463d-92fb-8b7bf3cb0905",
        "glycosylation": {
          "uuid": "3df73537-d262-42f0-a83a-3967044f8997"
        },
        "subunits": [
          {
            "uuid": "51ad3ea5-36ac-4dc3-8647-3bb1d06183fc",
            "sequence": "FNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD",
            "subunit_index": 1
          }
        ],
        "references": [
          "ec4fed9d-1983-4f86-8d05-97d44b84e748",
          "e0fb45e3-0b8d-40de-91f1-91aaf6f27533"
        ],
        "protein_sub_type": "",
        "sequence_type": "COMPLETE"
      },
      "properties": [
        {
          "uuid": "455fc9fb-e8cf-48c9-a2d2-8e7c22ac8ebf",
          "name": "MOL_WEIGHT:NUMBER(CALCULATED)",
          "type": "amount",
          "value": {
            "uuid": "b65229a2-7585-41b6-9f71-6ec45de332ec",
            "type": "ESTIMATED",
            "average": 15800,
            "units": "Da"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        },
        {
          "uuid": "598460ed-e415-4e58-9fdf-1c2db8e97415",
          "name": "Molecular Formula",
          "value": {
            "uuid": "b94a7850-4d40-4d6e-b9b9-72d5c74afe25",
            "type": "ESTIMATED",
            "non_numeric_value": "C706H1086N194O213S4"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "c29cd474-3b67-4ff3-8704-20127dfabe29"
      }
    }
  ]
}