{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-09-09",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "37079990-fe80-424a-af9c-b13484691722",
          "code": "6202-22-8",
          "type": "SUPERSEDED",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=6202-22-8",
          "code_system": "CAS",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911",
            "4f07be81-2fff-4798-a237-74d1e0da88b2"
          ]
        },
        {
          "uuid": "224b9b30-455f-4b60-989c-d2ad7aeb17d6",
          "code": "C001801",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67001801",
          "code_system": "MESH",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911"
          ]
        },
        {
          "uuid": "8df57615-a386-47d3-b318-c4affe717fed",
          "code": "MITRAGYNINE",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Mitragynine",
          "code_system": "WIKIPEDIA",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911"
          ]
        },
        {
          "uuid": "b005e2ee-c2bb-4ab0-9690-3c6a7efe99a8",
          "code": "4098-40-2",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=4098-40-2",
          "code_system": "CAS",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911",
            "f45f9feb-f16a-4495-9235-c333a859fd51"
          ]
        },
        {
          "uuid": "1bc218ff-88f7-48c1-ac2d-7ee539cf2af2",
          "code": "m7573",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m7573?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911"
          ]
        },
        {
          "uuid": "958c64df-3b5c-4e72-8068-ff7825cc3ac9",
          "code": "SUB75071",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911"
          ]
        },
        {
          "uuid": "21296717-6acd-42c3-a5c6-85d220ee2785",
          "code": "3034396",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/3034396",
          "code_system": "PUBCHEM",
          "references": [
            "1be65add-e041-4440-a720-60aad11a7911"
          ]
        },
        {
          "uuid": "d5bacb8f-b2cc-c6c8-6f93-eada2f8a328f",
          "code": "7901",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/source/hsdb/7901",
          "code_system": "HSDB",
          "references": [
            "1aeac579-3887-fa01-3065-0a22a35d47ac"
          ]
        },
        {
          "uuid": "65b94911-d9b6-4e55-9b89-985bceb9879f",
          "code": "EP479K822J",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "27e6c72e-58d8-24de-0cdf-6ea2587360ed",
          "code": "100000136870",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "ca0cffaa-a465-4745-1940-05a11ce6a4d2"
          ]
        },
        {
          "uuid": "5dc8d2c7-b710-09d2-c651-095ab80795b6",
          "code": "DTXSID701032140",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID701032140",
          "code_system": "EPA CompTox",
          "references": [
            "bf6e5049-a3a3-482f-c81f-628bccc96697"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "5018c197-cda2-49cf-922d-2b4b0bfbbb6b",
          "amount": {
            "uuid": "66db263d-c77f-4611-b84c-de1e5a00564e"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "c5a2f55f-2040-4a27-bcb1-787eb50415c4",
            "refuuid": "22e5b710-9260-4678-9196-ba75d4c38520",
            "name": "MITRAGYNINE",
            "unii": "EP479K822J",
            "linking_id": "EP479K822J",
            "ref_pname": "MITRAGYNINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "a2309a54-5e62-4d86-85f3-32d16e4029dd",
          "amount": {
            "uuid": "6e0a9cea-2d16-4cb3-b4bd-6a26569172f7"
          },
          "type": "TARGET->AGONIST",
          "references": [
            "9e873e3d-ec51-45e8-b2ad-3e70a9e676fb"
          ],
          "related_substance": {
            "uuid": "ec84b854-009f-467b-99ac-dd7d8c4c5ff5",
            "refuuid": "39262e4f-d963-4b83-9b34-52fd55036f0e",
            "name": "MU-TYPE OPIOID RECEPTOR",
            "unii": "1PE72K8X46",
            "linking_id": "1PE72K8X46",
            "ref_pname": "MU-TYPE OPIOID RECEPTOR",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "d4eb81ac-43c6-422d-b1e7-14e5655a6f3c",
          "amount": {
            "uuid": "2fb99a56-70ab-4d92-8fc8-b59155141df2"
          },
          "type": "METABOLITE->PARENT",
          "references": [
            "b3e6dfbe-c318-4e34-b916-e4c67b37385d"
          ],
          "related_substance": {
            "uuid": "a3b5a998-0d0b-4128-8bdf-f13448fb0075",
            "refuuid": "fb65535d-b6e2-4071-8de6-873892d45f36",
            "name": "17-CARBOXY-16,17-DIHYDROMITRAGYNINE",
            "unii": "CUX9JXG34F",
            "linking_id": "CUX9JXG34F",
            "ref_pname": "17-CARBOXY-16,17-DIHYDROMITRAGYNINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "0d9bc8b9-4c10-4388-90ca-f41869dde065",
          "amount": {
            "uuid": "d8943e32-c248-4e2f-8b41-bb63de73af82"
          },
          "qualification": "URINE",
          "type": "METABOLITE INACTIVE->PARENT",
          "references": [
            "209370dc-8afe-463e-b6b4-4bc012414579"
          ],
          "related_substance": {
            "uuid": "1545c687-d32e-412b-97c4-44a44eca11ce",
            "refuuid": "aeadbbaf-b852-4b2b-a671-11f73c2c8722",
            "name": "9-O-DEMETHYLMITRAGYNINE SULFATE ESTER",
            "unii": "MJQ8T5H9VM",
            "linking_id": "MJQ8T5H9VM",
            "ref_pname": "9-O-DEMETHYLMITRAGYNINE SULFATE ESTER",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "48436df0-6e7b-46d2-b274-21b41a0b432f",
          "amount": {
            "uuid": "145ef118-5c0a-44d8-9d66-2d846c6f56f8"
          },
          "qualification": "URINE",
          "type": "METABOLITE INACTIVE->PARENT",
          "references": [
            "7f158fd5-a087-41bd-8078-260c7bcb1b02"
          ],
          "related_substance": {
            "uuid": "103e01d8-fe2a-4ab1-bb29-1c882856b755",
            "refuuid": "f35cfd58-1cde-4cb6-aab4-402978bd35d7",
            "name": "9-O-DEMETHYLMITRAGYNINE GLUCORONIDE",
            "unii": "P82S5MND4M",
            "linking_id": "P82S5MND4M",
            "ref_pname": "9-O-DEMETHYLMITRAGYNINE GLUCORONIDE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "bc5e8e02-8e09-4b88-ba5d-edaacc878927",
          "amount": {
            "uuid": "d466ae20-4f5c-48d9-900d-57cb9203dd8f"
          },
          "type": "METABOLITE ACTIVE->PARENT",
          "mediator_substance": {
            "uuid": "535dc73e-305b-4084-b49d-93479a1de748",
            "refuuid": "4275827d-e329-4907-95b5-7d690692872a",
            "name": "CYTOCHROME P450 3A4",
            "unii": "PUO0521HZV",
            "linking_id": "PUO0521HZV",
            "ref_pname": "CYTOCHROME P450 3A4",
            "substance_class": "reference"
          },
          "references": [
            "c77d05e2-7a79-4ad1-90f5-a094e590c64d"
          ],
          "related_substance": {
            "uuid": "290bf90b-6fff-415d-85f4-4b5cd70c0a4b",
            "refuuid": "c50748a1-8231-42ad-a263-6abc6bc49005",
            "name": "7-HYDROXYMITRAGYNINE",
            "unii": "2T3TWA75R0",
            "linking_id": "2T3TWA75R0",
            "ref_pname": "7-HYDROXYMITRAGYNINE"
          }
        },
        {
          "uuid": "2e6b112a-d528-4773-8c3b-5e385b5a966f",
          "amount": {
            "uuid": "002886fd-6c2e-4e0a-929a-38d3731e82b9"
          },
          "comments": " ",
          "type": "METABOLITE ACTIVE->PARENT",
          "related_substance": {
            "uuid": "728f421e-1e6c-4555-bc02-788be3db88a0",
            "refuuid": "7ee341a5-8a5e-4aa7-afe2-3ec2fbeba811",
            "name": "MITRAGYNINE PSEUDOINDOXYL",
            "unii": "BKA67VHE3B",
            "linking_id": "BKA67VHE3B",
            "ref_pname": "MITRAGYNINE PSEUDOINDOXYL",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "64e83743-d0e3-4506-97ae-5394735a79e1",
          "amount": {
            "uuid": "c6396afa-b239-4798-9eba-7d7ed668970a"
          },
          "qualification": "URINE",
          "type": "METABOLITE->PARENT",
          "references": [
            "6a214687-0ac9-4e3d-881a-5059bd6f75ed"
          ],
          "related_substance": {
            "uuid": "596551e5-e81e-42f5-a6dd-6995b8835442",
            "refuuid": "1db1031a-38f3-4ea2-9d23-37429d2efbe0",
            "name": "9-O-DEMETHYLMITRAGYNINE",
            "unii": "RNE3SSW79R",
            "linking_id": "RNE3SSW79R",
            "ref_pname": "9-O-DEMETHYLMITRAGYNINE",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "761a3aff-6d62-467b-a696-c45689a6cbef",
          "name": "(-)-MITRAGYNINE",
          "stdName": "(-)-MITRAGYNINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "414291d5-f63f-493a-8dc8-e3fb5269b9ce"
          ],
          "display_name": false
        },
        {
          "uuid": "8b74ad15-305a-45b0-a0a1-311ea425ea48",
          "name": "(.ALPHA.E,2S,3S,12.BETA.S)-3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-8-METHOXY-.ALPHA.-(METHOXYMETHYLENE)-INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID METHYL ESTER",
          "stdName": "(.ALPHA.E,2S,3S,12.BETA.S)-3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-8-METHOXY-.ALPHA.-(METHOXYMETHYLENE)-INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID METHYL ESTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "18d4e47c-9a5b-4375-b95e-a3c3f4accadc"
          ],
          "display_name": false
        },
        {
          "uuid": "3a8f6937-4ef9-4584-b05e-d196508b53dc",
          "name": "9-METHOXYCORYNANTHEIDINE",
          "stdName": "9-METHOXYCORYNANTHEIDINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "18d4e47c-9a5b-4375-b95e-a3c3f4accadc"
          ],
          "display_name": false
        },
        {
          "uuid": "3437c490-711f-4284-badf-662e239b9f17",
          "name": "INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID, 3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-8-METHOXY-.ALPHA.-(METHOXYMETHYLENE)-, METHYL ESTER, (.ALPHA.E,2S,3S,12BS)-",
          "stdName": "INDOLO(2,3-A)QUINOLIZINE-2-ACETIC ACID, 3-ETHYL-1,2,3,4,6,7,12,12B-OCTAHYDRO-8-METHOXY-.ALPHA.-(METHOXYMETHYLENE)-, METHYL ESTER, (.ALPHA.E,2S,3S,12BS)-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "414291d5-f63f-493a-8dc8-e3fb5269b9ce"
          ],
          "display_name": false
        },
        {
          "uuid": "ea47c4e2-39f5-4fc7-96eb-372312b72de2",
          "name": "MITRAGYNIN",
          "stdName": "MITRAGYNIN",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "414291d5-f63f-493a-8dc8-e3fb5269b9ce"
          ],
          "display_name": false
        },
        {
          "uuid": "5d6e32cb-75e6-40e4-9a1a-cfdad2624f7c",
          "name": "MITRAGYNINE",
          "stdName": "MITRAGYNINE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "f02ce2c2-8b10-4eb2-a972-3ead6408da8f",
            "18d4e47c-9a5b-4375-b95e-a3c3f4accadc",
            "68da74b0-b2d1-4e4e-8d15-947b19e97ae4",
            "cb6aaa43-ff07-447c-a5d4-729ec50082a7"
          ],
          "display_name": true
        },
        {
          "uuid": "944f6a28-7fc8-45da-b654-f48e3681af3e",
          "name": "MITRAGYNINE [MI]",
          "stdName": "MITRAGYNINE [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
            "18d4e47c-9a5b-4375-b95e-a3c3f4accadc"
          ],
          "display_name": false
        },
        {
          "uuid": "73a21c2a-484a-0719-c608-f8a4d2df854b",
          "name": "Mitragynine [WHO-DD]",
          "stdName": "MITRAGYNINE [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "b23faa49-76af-bf8a-465a-be9763c2f25e"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "18d4e47c-9a5b-4375-b95e-a3c3f4accadc",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "d6973ec4-b100-489b-8ff1-f2d44c4e487b",
          "citation": "MERCK INDEX",
          "doc_type": "MERCK INDEX",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "414291d5-f63f-493a-8dc8-e3fb5269b9ce",
          "citation": "STN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "f02ce2c2-8b10-4eb2-a972-3ead6408da8f",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1be65add-e041-4440-a720-60aad11a7911",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389748000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "40ec903c-07b0-439f-b108-cb6705992ca7",
          "citation": "SRS import [EP479K822J]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=EP479K822J",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389748000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "261b1c25-0541-4b88-ad44-3c78f25b712a",
          "citation": "http://en.wikipedia.org/wiki/Mitragynine",
          "url": "http://en.wikipedia.org/wiki/Mitragynine",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "cb6aaa43-ff07-447c-a5d4-729ec50082a7",
          "citation": "MITRAGYNINE [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "68da74b0-b2d1-4e4e-8d15-947b19e97ae4",
          "citation": "MITRAGYNINE [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "1aeac579-3887-fa01-3065-0a22a35d47ac",
          "citation": "WEBSITE",
          "url": "https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+4098-40-2",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "bf6e5049-a3a3-482f-c81f-628bccc96697",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "f45f9feb-f16a-4495-9235-c333a859fd51",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "4f07be81-2fff-4798-a237-74d1e0da88b2",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "c77d05e2-7a79-4ad1-90f5-a094e590c64d",
          "citation": "Prozialeck, Walter C., Jateen K. Jivan, and Shridhar V. Andurkar. \"Pharmacology of kratom: an emerging botanical agent with stimulant, analgesic and opioid-like effects.\" The Journal of the American Osteopathic Association 112.12 (2012): 792-799.",
          "url": "https://jaoa.org/article.aspx?articleid=2094342",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "f3d02e07-4b32-4b25-975f-6ce1fb216a2a",
          "citation": "Philipp, Anika A., et al. \"Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography‐linear ion trap mass spectrometry.\" Journal of mass spectrometry 44.8 (2009): 1249-1261.",
          "url": "https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.1607?casa_token=y0fKkdvUR7kAAAAA%3A2e3XCgEyLcUzEoJJpemBGyKusvhjVR3UXWI37xgiz--MEWDGwobRTZHrnOo8WVh6FmKaZslooDy-wHQ",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "209370dc-8afe-463e-b6b4-4bc012414579",
          "citation": "Philipp, Anika A., et al. \"Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography‐linear ion trap mass spectrometry.\" Journal of mass spectrometry 44.8 (2009): 1249-1261.",
          "url": "https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.1607?casa_token=y0fKkdvUR7kAAAAA%3A2e3XCgEyLcUzEoJJpemBGyKusvhjVR3UXWI37xgiz--MEWDGwobRTZHrnOo8WVh6FmKaZslooDy-wHQ",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "7f158fd5-a087-41bd-8078-260c7bcb1b02",
          "citation": "Philipp, Anika A., et al. \"Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography‐linear ion trap mass spectrometry.\" Journal of mass spectrometry 44.8 (2009): 1249-1261.",
          "url": "https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.1607?casa_token=y0fKkdvUR7kAAAAA%3A2e3XCgEyLcUzEoJJpemBGyKusvhjVR3UXWI37xgiz--MEWDGwobRTZHrnOo8WVh6FmKaZslooDy-wHQ",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "b3e6dfbe-c318-4e34-b916-e4c67b37385d",
          "citation": "Philipp, Anika A., et al. \"Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography‐linear ion trap mass spectrometry.\" Journal of mass spectrometry 44.8 (2009): 1249-1261.",
          "url": "https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.1607?casa_token=y0fKkdvUR7kAAAAA%3A2e3XCgEyLcUzEoJJpemBGyKusvhjVR3UXWI37xgiz--MEWDGwobRTZHrnOo8WVh6FmKaZslooDy-wHQ",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "6a214687-0ac9-4e3d-881a-5059bd6f75ed",
          "citation": "Philipp, Anika A., et al. \"Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography‐linear ion trap mass spectrometry.\" Journal of mass spectrometry 44.8 (2009): 1249-1261.",
          "url": "https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.1607?casa_token=y0fKkdvUR7kAAAAA%3A2e3XCgEyLcUzEoJJpemBGyKusvhjVR3UXWI37xgiz--MEWDGwobRTZHrnOo8WVh6FmKaZslooDy-wHQ",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "9e873e3d-ec51-45e8-b2ad-3e70a9e676fb",
          "citation": "https://www.emcdda.europa.eu/publications/drug-profiles/kratom_en",
          "url": "https://www.emcdda.europa.eu/publications/drug-profiles/kratom_en",
          "doc_type": "WEB PAGE",
          "public_domain": true
        },
        {
          "uuid": "b23faa49-76af-bf8a-465a-be9763c2f25e",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "ca0cffaa-a465-4745-1940-05a11ce6a4d2",
          "citation": "EU-SRS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "d66b9b61-0fcc-4e86-8639-b0a3eb832fcb",
          "id": "d66b9b61-0fcc-4e86-8639-b0a3eb832fcb",
          "molfile": "\n  Marvin  01132111072D          \n\n 29 32  0  0  1  0            999 V2000\n    1.5332   -3.1002    0.0000 C   0  0  2  0  0  0  0  0  0  2  0  0\n    2.3453   -3.2746    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.9049   -2.6499    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.2833   -2.3140    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.4685   -2.1501    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    0.2135   -1.3666    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.5752   -1.1896    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.1245   -1.8065    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.8668   -2.6030    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.5306   -3.0845    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.2022   -2.6030    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.0038   -2.7722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.5687   -2.1553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.3188   -1.3744    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.5041   -1.2052    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.2464   -0.4165    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.8086    0.2031    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.9496   -1.8065    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.0625   -2.7722    0.0000 C   0  0  2  0  0  0  0  0  0  2  0  0\n    0.1666   -3.5452    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.9839   -3.7119    0.0000 C   0  0  2  0  0  0  0  0  0  2  0  0\n    1.2572   -4.4902    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.0564   -4.6568    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.6108   -4.0477    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    3.4152   -4.2168    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7054   -5.1097    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.1067   -4.9301    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    0.9476   -5.8802    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    1.9236   -6.1378    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  1  0  0  0\n  1  4  1  0  0  0  0\n  1 21  1  0  0  0  0\n  3  2  1  0  0  0  0\n  4  5  1  0  0  0  0\n  6  5  1  0  0  0  0\n  5 19  1  0  0  0  0\n  6  7  1  0  0  0  0\n  7  8  1  0  0  0  0\n  8  9  2  0  0  0  0\n 18  8  1  0  0  0  0\n 10  9  1  0  0  0  0\n 19  9  1  0  0  0  0\n 11 10  1  0  0  0  0\n 12 11  1  0  0  0  0\n 11 18  2  0  0  0  0\n 13 12  2  0  0  0  0\n 14 13  1  0  0  0  0\n 14 15  2  0  0  0  0\n 16 15  1  0  0  0  0\n 15 18  1  0  0  0  0\n 17 16  1  0  0  0  0\n 19 20  1  1  0  0  0\n 21 20  1  0  0  0  0\n 21 22  1  1  0  0  0\n 23 22  2  0  0  0  0\n 26 22  1  0  0  0  0\n 24 23  1  0  0  0  0\n 25 24  1  0  0  0  0\n 27 26  2  0  0  0  0\n 28 26  1  0  0  0  0\n 29 28  1  0  0  0  0\nM  END",
          "smiles": "CC[C@@H]1CN2CCc3c4c(cccc4OC)[nH]c3[C@@H]2C[C@@H]1/C(=C\\OC)/C(=O)OC",
          "formula": "C23H30N2O4",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ABSOLUTE",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "844738d4-df4e-479e-ba68-72cd426912e6"
          },
          "defined_stereo": 3,
          "ez_centers": 1,
          "molecular_weight": "398.4962",
          "optical_activity": "UNSPECIFIED",
          "stereo_centers": 3
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "22e5b710-9260-4678-9196-ba75d4c38520",
      "version": "21",
      "structure": {
        "id": "c3e8c702-8a69-4e6d-9343-551c931b2099",
        "molfile": "\n  Marvin  01132110082D          \n\n 30 33  0  0  1  0            999 V2000\n   -0.8665   -2.6026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.1243   -1.8064    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.5304   -3.0842    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    1.2570   -4.4897    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.0625   -2.7718    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n    0.4686   -2.1500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   -1.9495   -1.8064    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.9837   -3.7113    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n   -2.2021   -2.6026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.1666   -3.5450    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7055   -5.1093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.2831   -2.3136    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.5753   -1.1894    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.5330   -3.0999    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n    0.2135   -1.3664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.0563   -4.6563    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.5037   -1.2050    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.1067   -4.9297    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    0.9473   -5.8795    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.0035   -2.7718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.6104   -4.0471    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.2459   -0.4166    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    2.3449   -3.2743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.5685   -2.1552    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -3.3185   -1.3742    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.9235   -6.1372    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.4149   -4.2163    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -2.8082    0.2031    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.9046   -2.6495    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   -0.6456   -3.3524    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  2  0  0  0  0\n  3  1  1  0  0  0  0\n  8  4  1  1  0  0  0\n  5  1  1  0  0  0  0\n  6  5  1  0  0  0  0\n  7  2  1  0  0  0  0\n  8 10  1  0  0  0  0\n  9  3  1  0  0  0  0\n 10  5  1  0  0  0  0\n 11  4  1  0  0  0  0\n 12  6  1  0  0  0  0\n 13  2  1  0  0  0  0\n 14  8  1  0  0  0  0\n 15  6  1  0  0  0  0\n 16  4  2  0  0  0  0\n 17  7  1  0  0  0  0\n 18 11  2  0  0  0  0\n 19 11  1  0  0  0  0\n 20  9  1  0  0  0  0\n 21 16  1  0  0  0  0\n 22 17  1  0  0  0  0\n 14 23  1  1  0  0  0\n 24 20  2  0  0  0  0\n 25 17  2  0  0  0  0\n 26 19  1  0  0  0  0\n 27 21  1  0  0  0  0\n 28 22  1  0  0  0  0\n 29 23  1  0  0  0  0\n  9  7  2  0  0  0  0\n 15 13  1  0  0  0  0\n 14 12  1  0  0  0  0\n 25 24  1  0  0  0  0\n  5 30  1  6  0  0  0\nM  END",
        "smiles": "CC[C@@H]1CN2CCc3c4c(cccc4OC)[nH]c3[C@]2([H])C[C@@H]1/C(=C\\OC)/C(=O)OC",
        "formula": "C23H30N2O4",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ABSOLUTE",
        "defined_stereo": 3,
        "ez_centers": 1,
        "molecular_weight": "398.4962",
        "optical_activity": "( - )",
        "references": [
          "40ec903c-07b0-439f-b108-cb6705992ca7",
          "261b1c25-0541-4b88-ad44-3c78f25b712a"
        ],
        "stereo_centers": 3
      },
      "unii": "EP479K822J"
    }
  ]
}