{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "1b31ac62-bd56-40bd-b133-8971875be5da",
          "code": "1414-45-5",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=1414-45-5",
          "code_system": "CAS",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6",
            "0ac9bb37-620a-4d1a-8322-9ed8c8d88e0b"
          ]
        },
        {
          "uuid": "b5e8f3d2-3bb4-494a-9b1d-04a7ceede26b",
          "code": "C87602",
          "type": "PRIMARY",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C87602",
          "code_system": "NCI_THESAURUS",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "5426942b-6610-4ac3-ab66-fd092a52bb2f",
          "code": "NISIN",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Nisin",
          "code_system": "WIKIPEDIA",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "cd4cfcd2-1a6a-40e2-9129-aa02ef50f617",
          "code": "21 CFR 184.1538",
          "comments": "PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE|Subpart B--Listing of Specific Substances Affirmed as GRAS|Sec. 184.1538 Nisin preparation",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1538",
          "code_system": "CFR",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "f1e32a95-72c2-4ebf-b353-169398fe2492",
          "code": "INS-234",
          "comments": "JECFA|Functional Classification|Preservative",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemINS=234",
          "code_system": "JECFA EVALUATION",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "7f8bbea2-321a-4c47-8111-854b33ea6c4a",
          "code": "INS-234",
          "comments": "Codex Alimentarius|Functional Classification|Preservative",
          "type": "PRIMARY",
          "url": "http://www.fao.org/gsfaonline/additives/details.html?id=1",
          "code_system": "CODEX ALIMENTARIUS (GSFA)",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "af7c4bb6-bb90-4a85-91b0-66e2f078bbdf",
          "code": "215-807-5",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.014.370",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "cd11371d-5860-49c8-b32e-150e9c71bdf3",
          "code": "m7920",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m7920?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "1e318276-54cb-46d6-8085-f85d012d529b",
          "code": "SUB14655MIG",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "c57b09de-4164-4b5a-a423-c90597c581a6"
          ]
        },
        {
          "uuid": "ffe72661-f07d-7a34-7362-17500b4dbca4",
          "code": "C258",
          "comments": "Pharmacologic Substance[C1909]|Anti-Infective Agent[C254]|Antibiotic",
          "type": "CONCEPT",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C258",
          "code_system": "NCI_THESAURUS",
          "references": [
            "02198ba6-582f-d387-b0ce-54ac71ffb8e7"
          ]
        },
        {
          "uuid": "f8c20915-6aae-7004-8f18-805ae31c7571",
          "code": "1633 (Number of products:1)",
          "comments": "Dietary Supplement Label Database|Chemical|Nisin",
          "type": "PRIMARY",
          "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=1633&item=Nisin",
          "code_system": "DSLD",
          "references": [
            "02198ba6-582f-d387-b0ce-54ac71ffb8e7"
          ]
        },
        {
          "uuid": "4bc5d329-ece4-4dfd-a4da-b8a035d90fee",
          "code": "EN8XKG133D",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "5fe8b2cf-56ef-7862-1003-353e048df1c0",
          "code": "71629",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:71629",
          "code_system": "CHEBI",
          "references": [
            "02198ba6-582f-d387-b0ce-54ac71ffb8e7"
          ]
        },
        {
          "uuid": "0458d051-3217-5502-6730-b483231b7b7f",
          "code": "DTXSID20893678",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID20893678",
          "code_system": "EPA CompTox",
          "references": [
            "02198ba6-582f-d387-b0ce-54ac71ffb8e7"
          ]
        },
        {
          "uuid": "b3e5e7bf-d5a8-09f8-1fbb-5dd944d91c7b",
          "code": "112903",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=112903",
          "code_system": "NSC",
          "references": [
            "cd69790b-8bcb-0d1e-2597-f882cf891452"
          ]
        },
        {
          "uuid": "ddb8da13-236a-c660-243f-2a64e2cebf8c",
          "code": "65",
          "type": "PRIMARY",
          "url": "https://www.cfsanappsexternal.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=65",
          "code_system": "GRAS Notification (GRN No.)",
          "references": [
            "02198ba6-582f-d387-b0ce-54ac71ffb8e7"
          ]
        },
        {
          "uuid": "816d6ece-cb8a-22df-f61b-40c147c68544",
          "code": "155489900",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/155489900",
          "code_system": "PUBCHEM",
          "references": [
            "31d674ea-3fc3-586a-4dff-907b2bffde6a"
          ]
        },
        {
          "uuid": "54910e09-80a1-743e-5a2b-07e8cdf5efed",
          "code": "100000080016",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "f125ec9a-33b7-bb45-f0f9-6d9f1664c7c3"
          ]
        }
      ],
      "substance_class": "protein",
      "references": [
        {
          "uuid": "57905469-f0b2-4088-96a5-ee5004f84b91",
          "citation": "Merck 14.3",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "bf7fe91a-a800-4160-a2f3-e015a81ea811",
          "citation": "MERCK INDEX",
          "doc_type": "MERCK INDEX",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "f3eae290-5358-48ad-93c7-5723b10b0446",
          "citation": "MARTINDALE 2011",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "92634d01-9714-4a3b-bb4a-39427feb8e7f",
          "citation": "MERCK INDEX",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "76474707-ee1e-4034-9a29-fc2478acf4a3",
          "citation": "FCC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b54393c4-13cb-49cd-83c4-72a795af9cce",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "65b658e9-3687-422f-ab21-e88a92ba67c5",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8603b4d3-f881-4b5a-85e5-b6b7f7c104b1",
          "citation": "STN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "74a48782-6474-4dac-8979-7b332d726fbc",
          "citation": "http://www.codexalimentarius.net/gsfaonline/additives/details.html?id=1",
          "url": "http://www.codexalimentarius.net/gsfaonline/additives/details.html?id=1",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "54b6ba26-6967-44c7-93a3-de1e74ed0b37",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c57b09de-4164-4b5a-a423-c90597c581a6",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391428000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a3d43e22-61ee-49eb-bd8c-6bd1dd7cb9c1",
          "citation": "SRS import [EN8XKG133D]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=EN8XKG133D",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391428000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "72a3e0e3-b17a-46ce-9748-885baf275195",
          "citation": "NISIN [MART.]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "0fe4e323-928d-4e30-9d37-088f6de0247e",
          "citation": "NISIN [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "b56d891d-bac8-40ba-8aa6-b0416d764ea6",
          "citation": "NISIN A PREPARATION [FCC]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "e4884c9a-47b0-494c-b7e8-bb331d16e74c",
          "citation": "NISIN [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "269cc9b0-4605-466b-b401-dfad74c9d356",
          "citation": "NISIN [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "02198ba6-582f-d387-b0ce-54ac71ffb8e7",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "0ac9bb37-620a-4d1a-8322-9ed8c8d88e0b",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "cd69790b-8bcb-0d1e-2597-f882cf891452",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "6c51c76d-87ad-3cb2-a535-1ac0a7537e43",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "31d674ea-3fc3-586a-4dff-907b2bffde6a",
          "citation": "PUBCHEM",
          "doc_type": "PUBCHEM",
          "public_domain": true
        },
        {
          "uuid": "f125ec9a-33b7-bb45-f0f9-6d9f1664c7c3",
          "citation": "EMA 2023",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "5d9257f2-8ee4-494f-ac20-577ca8ef8fe2",
      "version": "26",
      "unii": "EN8XKG133D",
      "relationships": [
        {
          "uuid": "4b3efd51-1b23-44e2-a5f7-681854130edb",
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "a84f6e80-fbbb-464d-922e-f7c9a3077be9",
            "refuuid": "5d9257f2-8ee4-494f-ac20-577ca8ef8fe2",
            "name": "NISIN",
            "unii": "EN8XKG133D",
            "linking_id": "EN8XKG133D",
            "ref_pname": "NISIN",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "a0f4a9ce-c7a3-4f97-a7a1-180d2d821db0",
          "type": "SUBSTANCE->SUB_ALTERNATE",
          "related_substance": {
            "uuid": "55cc73dc-d905-4dc6-89cc-c310ef6c8c61",
            "refuuid": "62d79d22-56f9-4021-830b-7d1d1fcc78cf",
            "name": "ALTERNATIVE DEFINITION for [NISIN]",
            "linking_id": "62d79d22-56f9-4021-830b-7d1d1fcc78cf",
            "ref_pname": "NO NAME"
          }
        }
      ],
      "names": [
        {
          "uuid": "89a0a3ea-b08a-40db-809d-e325b55fa0fa",
          "name": "AMBICIN N",
          "stdName": "AMBICIN N",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8603b4d3-f881-4b5a-85e5-b6b7f7c104b1",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "7855d817-0aa6-4d1c-9959-99485680fccf",
          "name": "DELVOPLUS",
          "stdName": "DELVOPLUS",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8603b4d3-f881-4b5a-85e5-b6b7f7c104b1",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "afec0c75-a803-403e-b962-bcf86994832e",
          "name": "E-234",
          "stdName": "E-234",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "74a48782-6474-4dac-8979-7b332d726fbc"
          ],
          "display_name": false
        },
        {
          "uuid": "c580fc92-61ad-4dc0-9475-e5483932ebed",
          "name": "INS NO.234",
          "stdName": "INS NO.234",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "74a48782-6474-4dac-8979-7b332d726fbc"
          ],
          "display_name": false
        },
        {
          "uuid": "912df773-b58e-46ce-9e5f-85131761d8db",
          "name": "INS-234",
          "stdName": "INS-234",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "74a48782-6474-4dac-8979-7b332d726fbc"
          ],
          "display_name": false
        },
        {
          "uuid": "bcaa5971-79f1-4ac5-9bf6-6618de396c55",
          "name": "MICROGARD MG 300",
          "stdName": "MICROGARD MG 300",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8603b4d3-f881-4b5a-85e5-b6b7f7c104b1",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "cd2ef872-b045-4e8c-a09e-61b3d8a0fd12",
          "name": "NISIN",
          "stdName": "NISIN",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f3eae290-5358-48ad-93c7-5723b10b0446",
            "57905469-f0b2-4088-96a5-ee5004f84b91",
            "65b658e9-3687-422f-ab21-e88a92ba67c5",
            "b54393c4-13cb-49cd-83c4-72a795af9cce",
            "92634d01-9714-4a3b-bb4a-39427feb8e7f",
            "0fe4e323-928d-4e30-9d37-088f6de0247e",
            "72a3e0e3-b17a-46ce-9748-885baf275195",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "269cc9b0-4605-466b-b401-dfad74c9d356",
            "e4884c9a-47b0-494c-b7e8-bb331d16e74c"
          ],
          "display_name": true,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "6b9f99bf-82cd-481d-bb4b-706f60feeed1",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "c193ea39-fa39-454f-bc82-0dbee96cdd89",
          "name": "NISIN A",
          "stdName": "NISIN A",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "57905469-f0b2-4088-96a5-ee5004f84b91",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "be32d36b-395a-416e-8f31-dd5b6eb1a956",
          "name": "NISIN A PREPARATION",
          "stdName": "NISIN A PREPARATION",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "76474707-ee1e-4034-9a29-fc2478acf4a3",
            "b56d891d-bac8-40ba-8aa6-b0416d764ea6"
          ],
          "display_name": false
        },
        {
          "uuid": "b5a5ee37-0c37-430f-9b82-3fdc9fcf9b7e",
          "name": "NISIN A PREPARATION [FCC]",
          "stdName": "NISIN A PREPARATION [FCC]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "76474707-ee1e-4034-9a29-fc2478acf4a3"
          ],
          "display_name": false
        },
        {
          "uuid": "e9438da1-e848-4e20-ac45-f5782ba9907c",
          "name": "NISIN [MART.]",
          "stdName": "NISIN [MART.]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "f3eae290-5358-48ad-93c7-5723b10b0446"
          ],
          "display_name": false
        },
        {
          "uuid": "2597a0fa-8e60-4de4-9642-cfeb6424b438",
          "name": "NISIN [MI]",
          "stdName": "NISIN [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bf7fe91a-a800-4160-a2f3-e015a81ea811",
            "92634d01-9714-4a3b-bb4a-39427feb8e7f"
          ],
          "display_name": false
        },
        {
          "uuid": "77380d2f-f27c-4260-9cca-988c699b8249",
          "name": "NISITROL",
          "stdName": "NISITROL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8603b4d3-f881-4b5a-85e5-b6b7f7c104b1",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "a1f1493f-2ca8-4fa5-8743-900863fb7eb4",
          "name": "NSC-112903",
          "stdName": "NSC-112903",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "54b6ba26-6967-44c7-93a3-de1e74ed0b37",
            "bf7fe91a-a800-4160-a2f3-e015a81ea811"
          ],
          "display_name": false
        },
        {
          "uuid": "3635404d-5ebd-47d1-6aa4-c146150fa8fd",
          "name": "Nisin [WHO-DD]",
          "stdName": "NISIN [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "6c51c76d-87ad-3cb2-a535-1ac0a7537e43"
          ],
          "display_name": false
        }
      ],
      "protein": {
        "uuid": "8ec2a384-445c-4f52-b772-a6e47b936238",
        "glycosylation": {
          "uuid": "1045d0f2-11c3-401a-9888-f559a57955a8"
        },
        "subunits": [
          {
            "uuid": "512f2916-1cf9-44bd-a36f-16a9edfbab05",
            "sequence": "IXCIALCXPGCKXGALMGCNMKXAXCHCSIHVAK",
            "subunit_index": 1
          }
        ],
        "references": [
          "57905469-f0b2-4088-96a5-ee5004f84b91",
          "a3d43e22-61ee-49eb-bd8c-6bd1dd7cb9c1"
        ],
        "other_links": [
          {
            "uuid": "7f7210ea-8962-4191-acf0-59950306ece9",
            "sites": [
              {
                "residue_index": 3,
                "subunit_index": 1
              },
              {
                "residue_index": 7,
                "subunit_index": 1
              }
            ],
            "linkage_type": "SULFIDE CROSSLINK"
          },
          {
            "uuid": "54415de2-33ee-43a4-918f-6faf245ee4e3",
            "sites": [
              {
                "residue_index": 8,
                "subunit_index": 1
              },
              {
                "residue_index": 11,
                "subunit_index": 1
              }
            ],
            "linkage_type": "SULFIDE CROSSLINK"
          },
          {
            "uuid": "f2f90866-3073-464e-b7dc-fd8c1d320d2d",
            "sites": [
              {
                "residue_index": 13,
                "subunit_index": 1
              },
              {
                "residue_index": 19,
                "subunit_index": 1
              }
            ],
            "linkage_type": "SULFIDE CROSSLINK"
          },
          {
            "uuid": "1d118d06-22aa-498e-bc86-8da082a79815",
            "sites": [
              {
                "residue_index": 23,
                "subunit_index": 1
              },
              {
                "residue_index": 26,
                "subunit_index": 1
              }
            ],
            "linkage_type": "SULFIDE CROSSLINK"
          },
          {
            "uuid": "5bd2447a-ec93-4c72-9404-a3a1ef3b05c5",
            "sites": [
              {
                "residue_index": 25,
                "subunit_index": 1
              },
              {
                "residue_index": 28,
                "subunit_index": 1
              }
            ],
            "linkage_type": "SULFIDE CROSSLINK"
          }
        ],
        "protein_sub_type": "",
        "sequence_type": "COMPLETE"
      },
      "properties": [
        {
          "uuid": "ffb2b712-8b3c-45fe-a99f-b8c4bf5a8b83",
          "name": "MOL_WEIGHT",
          "type": "amount",
          "value": {
            "uuid": "eb017d67-f76a-4a43-943a-619300d0f9dd",
            "average": 3390,
            "units": "Da"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        },
        {
          "uuid": "52047a9a-31b1-4963-bd00-ad2771d50370",
          "name": "Molecular Formula",
          "value": {
            "uuid": "d9e8c5b1-b4c4-49ef-bc8e-ad1730e52716",
            "type": "ESTIMATED",
            "non_numeric_value": "C144H238O42N42S9"
          },
          "defining": false,
          "property_type": "CHEMICAL"
        }
      ],
      "modifications": {
        "uuid": "7e0b149d-8a01-458c-9f77-dd02bdc3eb2f",
        "structural_modifications": [
          {
            "uuid": "1e516d28-ad6d-4a26-96e8-61669d59fe02",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 3,
                "subunit_index": 1
              },
              {
                "residue_index": 7,
                "subunit_index": 1
              }
            ],
            "extent_amount": {
              "uuid": "8ea8f6eb-61a7-49a3-baad-822703c5b559",
              "references": [],
              "non_numeric_value": "COMPLETE"
            },
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "4a6ead7c-3eb7-4fbe-b7ed-66558b805851",
              "refuuid": "2fe9f745-31d1-4ead-b672-18bd3bee828f",
              "name": "LANTHIONINE, MESO-",
              "unii": "104T761S26",
              "linking_id": "104T761S26",
              "ref_pname": "LANTHIONINE, MESO-",
              "substance_class": "reference"
            },
            "residue_modified": "SERINE",
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          },
          {
            "uuid": "6a411ea3-1c55-4adf-acf8-327884a7558a",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 8,
                "subunit_index": 1
              },
              {
                "residue_index": 11,
                "subunit_index": 1
              }
            ],
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "f26f82ec-4489-4691-bc68-1644d7db6e62",
              "refuuid": "498d0e83-6e38-4741-bec6-04eb770d4edf",
              "name": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "unii": "MZ6AHU9TAO",
              "linking_id": "MZ6AHU9TAO",
              "ref_pname": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "substance_class": "reference"
            },
            "residue_modified": "THREONINE",
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          },
          {
            "uuid": "bd13dee1-9633-4959-a5d2-f2e361e6585e",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 2,
                "subunit_index": 1
              }
            ],
            "extent_amount": {
              "uuid": "c4f9ff39-0d42-40a7-af14-bd2eb7671ad7",
              "references": [],
              "non_numeric_value": "COMPLETE"
            },
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "55f46031-a92b-4b2d-a99d-17a53dead583",
              "refuuid": "aef0f5fc-3e89-4916-940b-2b624970854f",
              "name": "DEHYDROBUTYRINE, (2Z)-",
              "unii": "66QL1S96RM",
              "linking_id": "66QL1S96RM",
              "ref_pname": "DEHYDROBUTYRINE, (2Z)-",
              "substance_class": "reference"
            },
            "residue_modified": "THREONINE",
            "structural_modification_type": "AMINO ACID SUBSTITUTION"
          },
          {
            "uuid": "c0bded82-ba2a-4213-a39c-b0683753b02b",
            "extent": "COMPLETE",
            "sites": [
              {
                "residue_index": 5,
                "subunit_index": 1
              },
              {
                "residue_index": 33,
                "subunit_index": 1
              }
            ],
            "extent_amount": {
              "uuid": "a9417c03-25e1-4728-b97b-dc877e348ace",
              "references": [],
              "non_numeric_value": "COMPLETE"
            },
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "8143309f-85f5-45a0-a3ef-1cdde394cfdb",
              "refuuid": "ca70d5d2-276e-4aab-8980-2a929d468557",
              "name": "DEHYDROALANINE",
              "unii": "98RA387EKY",
              "linking_id": "98RA387EKY",
              "ref_pname": "DEHYDROALANINE",
              "substance_class": "reference"
            },
            "residue_modified": "SERINE",
            "structural_modification_type": "AMINO ACID SUBSTITUTION"
          },
          {
            "uuid": "d14ba8f8-631d-4093-a361-7f8224fa6759",
            "sites": [
              {
                "residue_index": 13,
                "subunit_index": 1
              },
              {
                "residue_index": 19,
                "subunit_index": 1
              }
            ],
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "42536c88-e3c4-4197-a6e7-9ef78fcb8a0c",
              "refuuid": "498d0e83-6e38-4741-bec6-04eb770d4edf",
              "name": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "unii": "MZ6AHU9TAO",
              "linking_id": "MZ6AHU9TAO",
              "ref_pname": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "substance_class": "reference"
            },
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          },
          {
            "uuid": "440edf20-7de0-4d90-9203-24f6a96cc5d2",
            "sites": [
              {
                "residue_index": 23,
                "subunit_index": 1
              },
              {
                "residue_index": 26,
                "subunit_index": 1
              }
            ],
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "fcaeaad1-b57c-40bb-bf8d-87c61b62ae81",
              "refuuid": "498d0e83-6e38-4741-bec6-04eb770d4edf",
              "name": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "unii": "MZ6AHU9TAO",
              "linking_id": "MZ6AHU9TAO",
              "ref_pname": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "substance_class": "reference"
            },
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          },
          {
            "uuid": "60794e20-31de-4caa-96ca-2c226d0952d0",
            "sites": [
              {
                "residue_index": 25,
                "subunit_index": 1
              },
              {
                "residue_index": 28,
                "subunit_index": 1
              }
            ],
            "location_type": "SITE_SPECIFIC",
            "molecular_fragment": {
              "uuid": "b162f1f9-2c2e-4e54-91f1-540de6e620d5",
              "refuuid": "498d0e83-6e38-4741-bec6-04eb770d4edf",
              "name": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "unii": "MZ6AHU9TAO",
              "linking_id": "MZ6AHU9TAO",
              "ref_pname": "3-METHYLLANTHIONINE, (2S,3S,6R)-",
              "substance_class": "reference"
            },
            "structural_modification_type": "AMINO_ACID_SUBSTITUTION"
          }
        ]
      }
    }
  ]
}