{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "2743ab1a-2fb0-4b13-80b5-89a53514aec9",
          "code": "108-59-8",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=108-59-8",
          "code_system": "CAS",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e",
            "86bec930-abd0-432c-9230-893dbbd9ca9b"
          ]
        },
        {
          "uuid": "85549674-12bb-49ea-867d-c41697481ec5",
          "code": "C005230",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67005230",
          "code_system": "MESH",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e"
          ]
        },
        {
          "uuid": "61d9d19d-f182-4e2f-a9a0-24bd82fc1975",
          "code": "DIMETHYL MALONATE",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Dimethyl_malonate",
          "code_system": "WIKIPEDIA",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e"
          ]
        },
        {
          "uuid": "aff3280d-87b0-4d16-9ccd-935a810c53b4",
          "code": "203-597-8",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.003.271",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e"
          ]
        },
        {
          "uuid": "d00b8812-9956-4fa0-9753-9b786406bfc4",
          "code": "m7438",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m7438?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e"
          ]
        },
        {
          "uuid": "2d226880-931b-4c03-9002-423a095a4f17",
          "code": "7943",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/7943",
          "code_system": "PUBCHEM",
          "references": [
            "e6a4f848-9fad-489d-82d6-c7b22757f66e"
          ]
        },
        {
          "uuid": "4904d52e-92e3-03e0-3823-56959452994e",
          "code": "DTXSID4029145",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID4029145",
          "code_system": "EPA CompTox",
          "references": [
            "1c420e73-b376-8ab3-00a5-9644f93346d9"
          ]
        },
        {
          "uuid": "349c4333-b167-46a6-92e4-61266f7a469a",
          "code": "EM8Y79998C",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "3c7dd45a-94c2-4977-b4ef-4ac9a7fc583b",
          "name": "Dimethyl malonate",
          "stdName": "DIMETHYL MALONATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "6f905af1-92f4-4c9d-b706-9ec39407594c",
            "27f17836-78c6-4f30-927c-46f9bfdd36f0"
          ],
          "display_name": true
        },
        {
          "uuid": "bf744d71-f642-45fc-8315-068cd7e59682",
          "name": "METHYL MALONATE",
          "stdName": "METHYL MALONATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "420b3acf-e654-480c-b469-10a31e745f94",
            "27f17836-78c6-4f30-927c-46f9bfdd36f0",
            "7d9ee2b4-cebb-4f71-8218-342e30009465",
            "b37f0d34-0160-410a-bef3-5bc78e48e15e"
          ],
          "display_name": false
        },
        {
          "uuid": "4473361f-c953-4503-b94a-518855538c6e",
          "name": "METHYL MALONATE [MI]",
          "stdName": "METHYL MALONATE [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "420b3acf-e654-480c-b469-10a31e745f94",
            "27f17836-78c6-4f30-927c-46f9bfdd36f0"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "b37f0d34-0160-410a-bef3-5bc78e48e15e",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "27f17836-78c6-4f30-927c-46f9bfdd36f0",
          "citation": "CHEMID",
          "doc_type": "CHEMID",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6f905af1-92f4-4c9d-b706-9ec39407594c",
          "citation": "tox21",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "420b3acf-e654-480c-b469-10a31e745f94",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e6a4f848-9fad-489d-82d6-c7b22757f66e",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391630000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fae6b11f-3ada-4ea4-81a4-35f3c30d0b14",
          "citation": "SRS import [EM8Y79998C]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=EM8Y79998C",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391630000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9ace9faa-f3bd-4912-8be0-b0dd3777197f",
          "citation": "CHEMID RECORD 108-59-8",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7d9ee2b4-cebb-4f71-8218-342e30009465",
          "citation": "METHYL MALONATE [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "1c420e73-b376-8ab3-00a5-9644f93346d9",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=108-59-8",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "86bec930-abd0-432c-9230-893dbbd9ca9b",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "00fb1a67-8db1-40a4-b4d0-23630ef54858",
          "id": "00fb1a67-8db1-40a4-b4d0-23630ef54858",
          "molfile": "\n  CDK     01102520092D\n\n  9  8  0  0  0  0  0  0  0  0999 V2000\n   27.9730   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   26.6220   -6.5260    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   25.2710   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   25.2710   -8.8660    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   23.9199   -6.5260    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.5690   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.5690   -8.8660    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   21.2180   -6.5260    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   19.8670   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  2  0  0  0  0\n  3  5  1  0  0  0  0\n  5  6  1  0  0  0  0\n  6  7  2  0  0  0  0\n  6  8  1  0  0  0  0\n  8  9  1  0  0  0  0\nM  END",
          "smiles": "COC(=O)CC(=O)OC",
          "formula": "C5H8O4",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "e5087a74-a4af-425e-a9f8-f4166e9ee392"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "132.1148",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "22b577c7-fa64-48ae-aa93-c02eada2206a",
      "version": "11",
      "structure": {
        "id": "b587cec5-3f93-4d2a-90ad-d9f2a3598f60",
        "molfile": "\n   JSDraw201102520092D\n\n  9  8  0  0  0  0              0 V2000\n   27.9730   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   26.6220   -6.5260    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   25.2710   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   25.2710   -8.8660    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   23.9199   -6.5260    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.5690   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   22.5690   -8.8660    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   21.2180   -6.5260    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   19.8670   -7.3060    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  2  0  0  0  0\n  3  5  1  0  0  0  0\n  5  6  1  0  0  0  0\n  6  7  2  0  0  0  0\n  6  8  1  0  0  0  0\n  8  9  1  0  0  0  0\nM  END",
        "smiles": "COC(=O)CC(=O)OC",
        "formula": "C5H8O4",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "132.1148",
        "optical_activity": "NONE",
        "references": [
          "fae6b11f-3ada-4ea4-81a4-35f3c30d0b14",
          "9ace9faa-f3bd-4912-8be0-b0dd3777197f"
        ],
        "stereo_centers": 0
      },
      "unii": "EM8Y79998C"
    }
  ]
}