{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "8ffa2c97-2853-47bf-98c1-c3e23d3c4c2e",
          "code": "31249",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/31249",
          "code_system": "PUBCHEM",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f"
          ]
        },
        {
          "uuid": "0f905615-b6e0-4a75-ba2d-20e874cae099",
          "code": "DIETHYL SUCCINATE",
          "comments": "JECFA|FUNCTIONAL CLASSIFICATION|Flavouring Agent",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=2298",
          "code_system": "JECFA EVALUATION",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f"
          ]
        },
        {
          "uuid": "de94b631-3d94-4311-a841-f81c93ab1a15",
          "code": "123-25-1",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=123-25-1",
          "code_system": "CAS",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f",
            "c5680e46-5744-4bef-8c58-2fe60f674b52"
          ]
        },
        {
          "uuid": "9b13b93b-7d8f-4a16-95e8-cbd484cfcb2d",
          "code": "21 CFR 172.515",
          "comments": "PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION|Subpart F--Flavoring Agents and Related Substances|Sec. 172.515 Synthetic flavoring substances and adjuvants.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=172.515",
          "code_system": "CFR",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f"
          ]
        },
        {
          "uuid": "d6d5542f-0068-435b-a091-5cc5de5d671f",
          "code": "204-612-0",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.004.194",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f"
          ]
        },
        {
          "uuid": "971391cf-6109-47af-9c0d-11b3442f1fa0",
          "code": "m10269",
          "comments": "Merck Index",
          "type": "PRIMARY",
          "url": "https://merckindex.rsc.org/monographs/m10269?q=authorize",
          "code_system": "MERCK INDEX",
          "references": [
            "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f"
          ]
        },
        {
          "uuid": "c118d787-a042-f7fd-61c5-e9c25ba38a85",
          "code": "DTXSID2038732",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID2038732",
          "code_system": "EPA CompTox",
          "references": [
            "4367fb46-8714-1a42-c06d-d1091a684672"
          ]
        },
        {
          "uuid": "1c5fda88-2905-4316-884b-5a6649568ecd",
          "code": "ELP55C13DR",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "2a99ca70-db96-471e-1b4b-e4b2793bbc05",
          "code": "Diethyl succinate",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/Diethyl_succinate",
          "code_system": "WIKIPEDIA",
          "references": [
            "13672ab5-732d-2e65-e685-03326561ab1b"
          ]
        },
        {
          "uuid": "094a68ad-2973-5962-545a-9b2bb18ad22b",
          "code": "8875",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=8875",
          "code_system": "NSC",
          "references": [
            "f16235c9-1b20-9c17-3f6f-548f6ded1719"
          ]
        },
        {
          "uuid": "f9662e6b-3c92-959f-8e5e-80eac350e3e1",
          "code": "1115",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/1115/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "dd11f1e0-62fd-3f18-a225-01c035134776"
          ]
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "fc2c7821-0130-45fb-ba78-ac79b137fccc",
          "name": "BUTANEDIOIC ACID, 1,4-DIETHYL ESTER",
          "stdName": "BUTANEDIOIC ACID, 1,4-DIETHYL ESTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "d138bf57-9b0c-4958-b626-f5f912542db3"
          ],
          "display_name": false
        },
        {
          "uuid": "1dbc40b8-ccdc-497e-aab1-e62cfc7dec17",
          "name": "BUTANEDIOIC ACID, DIETHYL ESTER",
          "stdName": "BUTANEDIOIC ACID, DIETHYL ESTER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "58d18cbd-cfdf-414c-ab94-195846424c7e",
            "d08ed1c5-f8e1-42da-a961-6a7877254208"
          ],
          "display_name": false
        },
        {
          "uuid": "30c7c829-87f8-4d3c-a194-4301e2fdc62c",
          "name": "CLORIUS",
          "stdName": "CLORIUS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "af47b360-a6f4-4b5f-920c-6e5d914a7116"
          ],
          "display_name": false
        },
        {
          "uuid": "7c427e0b-8b70-4624-99ec-b591793ef69f",
          "name": "DIETHYL BUTANEDIOATE",
          "stdName": "DIETHYL BUTANEDIOATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "58d18cbd-cfdf-414c-ab94-195846424c7e",
            "d08ed1c5-f8e1-42da-a961-6a7877254208"
          ],
          "display_name": false
        },
        {
          "uuid": "df1441aa-4225-4b6b-8b5d-90fd5d2f8850",
          "name": "DIETHYL SUCCINATE",
          "stdName": "DIETHYL SUCCINATE",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "58d18cbd-cfdf-414c-ab94-195846424c7e",
            "5299f56d-fe6d-4e15-9755-974088a4f83f",
            "3552468d-9b39-4018-ad89-99d76d1072d6",
            "b4f339fc-34b1-4925-bea9-ff1bb92313cf",
            "fa0acb04-81d1-494e-8a93-7fb815516485",
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "c700782f-a047-4fb7-adf8-898341295f93",
            "9eebac34-0b26-4cd1-8762-c7ce16d7acc3",
            "ec45fcba-4158-46c8-99d5-f0f060d9fc84"
          ],
          "display_name": true,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "901b9128-680b-47d2-a9c8-4a7852b76f91",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "6c4f1baa-3892-4972-b36c-d16c4ae8ba98",
          "name": "DIETHYL SUCCINATE [FCC]",
          "stdName": "DIETHYL SUCCINATE [FCC]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "c700782f-a047-4fb7-adf8-898341295f93"
          ],
          "display_name": false
        },
        {
          "uuid": "15b8ff63-4b36-41a7-9fbe-5231fe2d1a2e",
          "name": "DIETHYL SUCCINATE [FHFI]",
          "stdName": "DIETHYL SUCCINATE [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "3552468d-9b39-4018-ad89-99d76d1072d6"
          ],
          "display_name": false
        },
        {
          "uuid": "0b248372-2a6c-4c3d-ac7d-80defe1064aa",
          "name": "ETHYL SUCCINATE",
          "stdName": "ETHYL SUCCINATE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "d138bf57-9b0c-4958-b626-f5f912542db3"
          ],
          "display_name": false
        },
        {
          "uuid": "3c841e34-3858-40c7-ada0-82b0130aaf1c",
          "name": "FEMA NO. 2377",
          "stdName": "FEMA NO. 2377",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "d138bf57-9b0c-4958-b626-f5f912542db3"
          ],
          "display_name": false
        },
        {
          "uuid": "85f2f686-b5a3-411f-b072-cb7fba0d485b",
          "name": "NSC-8875",
          "stdName": "NSC-8875",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "58d18cbd-cfdf-414c-ab94-195846424c7e",
            "d08ed1c5-f8e1-42da-a961-6a7877254208"
          ],
          "display_name": false
        },
        {
          "uuid": "0d1fbd87-c210-4a38-955a-c5d7a866943f",
          "name": "SUCCINIC ACID DIETHYL ESTER",
          "stdName": "SUCCINIC ACID DIETHYL ESTER",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3a4ae291-4d77-4984-b64c-37e5fd4f313b",
            "d08ed1c5-f8e1-42da-a961-6a7877254208",
            "ec963b70-0cd5-479d-ace6-6e61e69ce280"
          ],
          "display_name": false
        },
        {
          "uuid": "bbfa34c0-ed57-4cf1-8cb6-8c5062f47f91",
          "name": "SUCCINIC ACID DIETHYL ESTER [MI]",
          "stdName": "SUCCINIC ACID DIETHYL ESTER [MI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3a4ae291-4d77-4984-b64c-37e5fd4f313b",
            "d08ed1c5-f8e1-42da-a961-6a7877254208"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "58d18cbd-cfdf-414c-ab94-195846424c7e",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "9eebac34-0b26-4cd1-8762-c7ce16d7acc3",
          "citation": "DL",
          "doc_type": "CHEMID",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d138bf57-9b0c-4958-b626-f5f912542db3",
          "citation": "ChemID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d08ed1c5-f8e1-42da-a961-6a7877254208",
          "citation": "CHEMID",
          "doc_type": "CHEMID",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "af47b360-a6f4-4b5f-920c-6e5d914a7116",
          "citation": "VAN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3552468d-9b39-4018-ad89-99d76d1072d6",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b4f339fc-34b1-4925-bea9-ff1bb92313cf",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c700782f-a047-4fb7-adf8-898341295f93",
          "citation": "FCC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3a4ae291-4d77-4984-b64c-37e5fd4f313b",
          "citation": "MERCK",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6e2b4ebf-55e8-43df-a53a-f1e216ad6c6f",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391896000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "96b5ca39-ba6c-42fe-90fd-5061d144c0ce",
          "citation": "SRS import [ELP55C13DR]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=ELP55C13DR",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391896000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "5299f56d-fe6d-4e15-9755-974088a4f83f",
          "citation": "DIETHYL SUCCINATE [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "ec45fcba-4158-46c8-99d5-f0f060d9fc84",
          "citation": "DIETHYL SUCCINATE [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "fa0acb04-81d1-494e-8a93-7fb815516485",
          "citation": "DIETHYL SUCCINATE [FCC]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "ec963b70-0cd5-479d-ace6-6e61e69ce280",
          "citation": "SUCCINIC ACID DIETHYL ESTER [MI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "4367fb46-8714-1a42-c06d-d1091a684672",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=123-25-1",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "13672ab5-732d-2e65-e685-03326561ab1b",
          "citation": "WIKI",
          "doc_type": "WIKI",
          "public_domain": true
        },
        {
          "uuid": "c5680e46-5744-4bef-8c58-2fe60f674b52",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "f16235c9-1b20-9c17-3f6f-548f6ded1719",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "dd11f1e0-62fd-3f18-a225-01c035134776",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "2eb97081-6630-4efa-8c52-31843a67170e",
          "id": "2eb97081-6630-4efa-8c52-31843a67170e",
          "molfile": "\n  Marvin  01132102312D          \n\n 12 11  0  0  0  0            999 V2000\n    6.4506   -0.6662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.7407   -1.0880    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.0025   -0.7202    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.3004   -1.1420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.3287   -1.9599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5674   -0.7742    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8807   -1.1831    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1322   -0.8179    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1091    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4429   -1.2500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7047   -0.8668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -1.2963    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  1  0  0  0  0\n  5  4  2  0  0  0  0\n  6  4  1  0  0  0  0\n  7  6  1  0  0  0  0\n  8  7  1  0  0  0  0\n  9  8  2  0  0  0  0\n 10  8  1  0  0  0  0\n 11 10  1  0  0  0  0\n 12 11  1  0  0  0  0\nM  END",
          "smiles": "CCOC(=O)CCC(=O)OCC",
          "formula": "C8H14O4",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "867ff606-b2a4-4c3e-a6f1-f8b87a80ed83"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "174.1947",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "7d07509d-4c21-4d1a-8671-862719fdf374",
      "version": "10",
      "structure": {
        "id": "4163245d-e1aa-4b54-8cf5-5a8f8010a65c",
        "molfile": "\n  Marvin  01132103272D          \n\n 12 11  0  0  0  0            999 V2000\n    4.3004   -1.1420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1322   -0.8179    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.1091    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.3287   -1.9599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5674   -0.7742    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    2.8807   -1.1831    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.0025   -0.7202    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    1.4429   -1.2500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.7407   -1.0880    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.7047   -0.8668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.4506   -0.6662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -1.2963    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  2  6  1  0  0  0  0\n  3  2  2  0  0  0  0\n  4  1  2  0  0  0  0\n  5  1  1  0  0  0  0\n  6  5  1  0  0  0  0\n  7  1  1  0  0  0  0\n  8  2  1  0  0  0  0\n  9  7  1  0  0  0  0\n 10  8  1  0  0  0  0\n 11  9  1  0  0  0  0\n 12 10  1  0  0  0  0\nM  END",
        "smiles": "CCOC(=O)CCC(=O)OCC",
        "formula": "C8H14O4",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "174.1947",
        "optical_activity": "NONE",
        "references": [
          "96b5ca39-ba6c-42fe-90fd-5061d144c0ce",
          "58d18cbd-cfdf-414c-ab94-195846424c7e"
        ],
        "stereo_centers": 0
      },
      "unii": "ELP55C13DR"
    }
  ]
}