{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "d07c75c1-14e3-4d2c-81ac-6bc9f6c32f17",
          "code": "541-47-9",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=541-47-9",
          "code_system": "CAS",
          "references": [
            "c3c84cd7-cebe-4efc-91c8-458d6fb9d519",
            "26030b0f-9472-438e-85ae-4f6a3fc6a992"
          ]
        },
        {
          "uuid": "882b0c5a-f03d-43c4-9775-69f95bb96ee2",
          "code": "208-782-7",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.007.985",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "c3c84cd7-cebe-4efc-91c8-458d6fb9d519"
          ]
        },
        {
          "uuid": "e9d20e33-c7c8-4219-aef3-c5febdb801d5",
          "code": "10931",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/10931",
          "code_system": "PUBCHEM",
          "references": [
            "c3c84cd7-cebe-4efc-91c8-458d6fb9d519"
          ]
        },
        {
          "uuid": "c5688570-f710-f6cd-beb2-4ca8d2d0d15e",
          "code": "DTXSID2047145",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID2047145",
          "code_system": "EPA CompTox",
          "references": [
            "cff9b1bf-8571-be67-913c-4f011c9fb0d7"
          ]
        },
        {
          "uuid": "7721a390-4e9f-8e91-f1c7-9b2d3d006369",
          "code": "37127",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:37127",
          "code_system": "CHEBI",
          "references": [
            "ace0c208-51f9-5b14-223d-8250b8d5ed78"
          ]
        },
        {
          "uuid": "7f6ed52b-e9f9-4535-8b1b-0990d63e6bbe",
          "code": "EKV8I38F9I",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "54733574-dccd-a30b-b845-5c8f7c9a486c",
          "code": "97179",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=97179",
          "code_system": "NSC",
          "references": [
            "d87f4d88-bd2c-811b-db1b-0f25f9840f56"
          ]
        },
        {
          "uuid": "97a46c52-bbd4-950a-c7d2-a58b00c017c1",
          "code": "2549",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=2549",
          "code_system": "NSC",
          "references": [
            "d87f4d88-bd2c-811b-db1b-0f25f9840f56"
          ]
        },
        {
          "uuid": "35de5fe4-a5e4-4024-3f21-574604ee4d45",
          "code": "1213",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/1213/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "6864df70-1451-3181-0f1d-e2e00c32447b"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "88877b80-c6e9-4beb-88a0-7503869d60e8",
          "comments": "Esterifying acid of sesquiterpenes found in Butterbur.",
          "type": "PARENT->CONSTITUENT ALWAYS PRESENT",
          "references": [
            "cfadcea2-ad6e-4272-9e69-beb4e6c0e23f"
          ],
          "related_substance": {
            "uuid": "5425da5c-2c7f-45c9-8af4-81f75fe0a95e",
            "refuuid": "f3220597-808f-42e2-9f1e-f54725fbf713",
            "name": "PETASITES HYBRIDUS ROOT",
            "unii": "97S2809V5R",
            "linking_id": "97S2809V5R",
            "ref_pname": "PETASITES HYBRIDUS ROOT",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "5d48fbcc-2885-4baf-acb2-9a076c14100a",
          "name": "2-BUTENOIC ACID, 3-METHYL-",
          "stdName": "2-BUTENOIC ACID, 3-METHYL-",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9e6af33f-bdf9-43c5-8d82-b3128e54cdda"
          ],
          "display_name": false
        },
        {
          "uuid": "6428093c-1d49-4987-8100-17ba0de0f95e",
          "name": "3,3-DIMETHYACRYLIC ACID",
          "stdName": "3,3-DIMETHYACRYLIC ACID",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9e6af33f-bdf9-43c5-8d82-b3128e54cdda"
          ],
          "display_name": false
        },
        {
          "uuid": "f7939567-8a16-4916-9241-c6dbe244816f",
          "name": "3,3-DIMETHYLACRYLIC ACID",
          "stdName": "3,3-DIMETHYLACRYLIC ACID",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "424f0786-ec92-47a4-bbdf-5f2fde324b81"
          ],
          "display_name": false
        },
        {
          "uuid": "be932c97-abca-49d7-8bc4-6fa151198ca6",
          "name": "3-METHYL CROTONIC ACID",
          "stdName": "3-METHYL CROTONIC ACID",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "81637be4-b9c4-41f2-8465-50df49419496",
            "2a0d56de-72f1-4515-9e65-1607dede7b01",
            "08d85648-f029-47da-8e8e-31b4eec53d30"
          ],
          "display_name": true
        },
        {
          "uuid": "158abdf9-e5c9-4815-9418-943e826e7745",
          "name": "3-METHYL CROTONIC ACID [FHFI]",
          "stdName": "3-METHYL CROTONIC ACID [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "08d85648-f029-47da-8e8e-31b4eec53d30"
          ],
          "display_name": false
        },
        {
          "uuid": "9c54d1b5-e6f7-4e81-a03b-4b070363eacb",
          "name": "3-METHYLCROTONIC ACID",
          "stdName": "3-METHYLCROTONIC ACID",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9b3e5abc-e719-4617-9673-94df04ecaa43"
          ],
          "display_name": false
        },
        {
          "uuid": "aa952e70-b575-407e-b685-02ab44ce893b",
          "name": "FEMA NO. 3187",
          "stdName": "FEMA NO. 3187",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "d5429e3a-93be-401a-83d0-38296b22422c",
            "9f3879b6-d3e4-48ec-96ba-adf086610b97"
          ],
          "display_name": false
        },
        {
          "uuid": "344d2bdb-d54b-4b5e-ab23-13936f2d09f0",
          "name": "METHYLCROTONIC ACID",
          "stdName": "METHYLCROTONIC ACID",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "bade06da-ebec-4429-b859-9a712d299caf"
          ],
          "display_name": false
        },
        {
          "uuid": "289640f6-57bf-4fcf-a0b7-ad0633f90f9b",
          "name": "NSC-2549",
          "stdName": "NSC-2549",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86932f4c-cbe4-4a64-a11e-93f4e423f986"
          ],
          "display_name": false
        },
        {
          "uuid": "36425d20-0638-4a79-a5d9-2fb51480c761",
          "name": "NSC-97179",
          "stdName": "NSC-97179",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86932f4c-cbe4-4a64-a11e-93f4e423f986"
          ],
          "display_name": false
        },
        {
          "uuid": "f9f46507-50ef-4b31-96e2-9d3029bd8983",
          "name": "SENECIOIC ACID",
          "stdName": "SENECIOIC ACID",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "9e6af33f-bdf9-43c5-8d82-b3128e54cdda"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "9f3879b6-d3e4-48ec-96ba-adf086610b97",
          "citation": "CHEMID FEMA BATCH 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "d5429e3a-93be-401a-83d0-38296b22422c",
          "citation": "CHEMID BATCH 2010",
          "doc_type": "CHEMID",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "81637be4-b9c4-41f2-8465-50df49419496",
          "citation": "GRAS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9e6af33f-bdf9-43c5-8d82-b3128e54cdda",
          "citation": "stn",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "08d85648-f029-47da-8e8e-31b4eec53d30",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9b3e5abc-e719-4617-9673-94df04ecaa43",
          "citation": "CFSAN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "bade06da-ebec-4429-b859-9a712d299caf",
          "citation": "Herbal Medicines 4th ED 2103",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "86932f4c-cbe4-4a64-a11e-93f4e423f986",
          "citation": "SCIFINDER",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "424f0786-ec92-47a4-bbdf-5f2fde324b81",
          "citation": "TOX 21",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c3c84cd7-cebe-4efc-91c8-458d6fb9d519",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390975000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "cfadcea2-ad6e-4272-9e69-beb4e6c0e23f",
          "citation": "HERBAL MEDICINES 4TH ED 2103",
          "doc_type": "BOOK",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "91ed487c-f893-481b-8174-f2c0317e1cf4",
          "citation": "SRS import [EKV8I38F9I]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=EKV8I38F9I",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390975000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d46c365c-b87b-432c-9264-466b9b55dfd7",
          "citation": "CHEMID 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "2a0d56de-72f1-4515-9e65-1607dede7b01",
          "citation": "3-METHYL CROTONIC ACID [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "cff9b1bf-8571-be67-913c-4f011c9fb0d7",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=541-47-9",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "26030b0f-9472-438e-85ae-4f6a3fc6a992",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "ace0c208-51f9-5b14-223d-8250b8d5ed78",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "6864df70-1451-3181-0f1d-e2e00c32447b",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        },
        {
          "uuid": "d87f4d88-bd2c-811b-db1b-0f25f9840f56",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "4970604e-5221-4963-89d1-41d43052c461",
          "id": "4970604e-5221-4963-89d1-41d43052c461",
          "molfile": "\n  Marvin  01132103512D          \n\n  7  6  0  0  0  0            999 V2000\n    8.2055   -5.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4939   -4.8521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4939   -4.0743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.7864   -5.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.0663   -4.8521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.3548   -5.2696    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.0663   -4.0236    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  2  3  1  0  0  0  0\n  2  4  2  0  0  0  0\n  4  5  1  0  0  0  0\n  5  6  1  0  0  0  0\n  5  7  2  0  0  0  0\nM  END",
          "smiles": "CC(=CC(=O)O)C",
          "formula": "C5H8O2",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "0460b841-05f6-4f92-9103-949de0231161"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "100.116",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "21071eff-342c-4074-a2f8-351474e05e48",
      "version": "7",
      "structure": {
        "id": "82a31c5c-4e85-4a84-9c17-27fe896729e7",
        "molfile": "\n  Marvin  01132106472D          \n\n  7  6  0  0  0  0            999 V2000\n    7.4939   -4.8521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.7864   -5.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.0663   -4.8521    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.3548   -5.2696    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.0663   -4.0236    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    8.2055   -5.2696    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4939   -4.0743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  2  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  1  0  0  0  0\n  3  5  2  0  0  0  0\n  1  6  1  0  0  0  0\n  1  7  1  0  0  0  0\nM  END",
        "smiles": "CC(=CC(=O)O)C",
        "formula": "C5H8O2",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "100.116",
        "optical_activity": "NONE",
        "references": [
          "d46c365c-b87b-432c-9264-466b9b55dfd7",
          "91ed487c-f893-481b-8174-f2c0317e1cf4"
        ],
        "stereo_centers": 0
      },
      "unii": "EKV8I38F9I"
    }
  ]
}