{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "5338af73-78a0-4021-8a1a-30a83d2bbf11",
          "code": "61844",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/61844",
          "code_system": "PUBCHEM",
          "references": [
            "6ba59d74-b50a-4ab0-944c-6231dd9847f3"
          ]
        },
        {
          "uuid": "e30e1f44-a0a9-4bf3-9b30-a9bdd3745275",
          "code": "219-489-9",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.017.718",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "6ba59d74-b50a-4ab0-944c-6231dd9847f3"
          ]
        },
        {
          "uuid": "7e2562be-dd9a-4c85-85a1-fe1192ebb4fa",
          "code": "2445-53-6",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=2445-53-6",
          "code_system": "CAS",
          "references": [
            "6ba59d74-b50a-4ab0-944c-6231dd9847f3",
            "e3cfce15-1099-404e-96bb-0940055078cc"
          ]
        },
        {
          "uuid": "e2bbdb6a-5a33-455a-ba1b-65cff51c10ed",
          "code": "1312740",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/1312740/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "6ba59d74-b50a-4ab0-944c-6231dd9847f3"
          ]
        },
        {
          "uuid": "3edf1302-8427-60bd-04e9-952fb05cc66c",
          "code": "DTXSID10179211",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID10179211",
          "code_system": "EPA CompTox",
          "references": [
            "9932a73d-18ed-5596-e28d-80b754afed7e"
          ]
        },
        {
          "uuid": "4d4a33d6-556c-deda-116e-778103307e24",
          "code": "25342",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:25342",
          "code_system": "CHEBI",
          "references": [
            "60d651c2-6d35-b65c-24f6-35a3b2cb5784"
          ]
        },
        {
          "uuid": "cdbf0434-c3cd-4b18-ac96-28533f8d188b",
          "code": "E52D0J3TS5",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "45eb575f-ef81-3952-3937-7088482c43dc",
          "code": "E52D0J3TS5",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=E52D0J3TS5",
          "code_system": "DAILYMED",
          "references": [
            "69f2fc92-3103-3338-d237-d9c76fde138b"
          ]
        },
        {
          "uuid": "d410eaf6-f7a7-7753-3499-45b5bad5f14e",
          "code": "300000038674",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "e69043dc-1f81-f9bb-203f-934c2a018de7"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "fbb9f0e5-c2c1-4d53-ba5b-6211ade36463",
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "f5ffe238-ad2c-4a50-af62-fa5fc50c4b18",
            "refuuid": "aaa28520-2073-4a42-91f6-bee1a1895aa2",
            "name": "SILANETRIOL",
            "unii": "E52D0J3TS5",
            "linking_id": "E52D0J3TS5",
            "ref_pname": "SILANETRIOL",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "3715d811-54e4-4c4e-80f0-a850dce89553",
          "amount": {
            "uuid": "5fe31440-0c96-46df-b4a0-2466a975f714"
          },
          "type": "PRODRUG->METABOLITE ACTIVE",
          "references": [
            "58cb3f74-86b7-48b7-97da-8bf97d49b4b6"
          ],
          "related_substance": {
            "uuid": "ef9d1412-d19d-4b73-b34c-ef763988982b",
            "refuuid": "e1e150d8-fcb7-4b90-a910-c81e20ba6328",
            "name": "MONOMETHYLTRISILANOL SALICYLATE",
            "unii": "T4S4WQP2BH",
            "linking_id": "T4S4WQP2BH",
            "ref_pname": "MONOMETHYLTRISILANOL SALICYLATE",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "8b8de552-cc00-4ca5-9434-1e0368c6ea7b",
          "name": "SILANETRIOL",
          "stdName": "SILANETRIOL",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a212f80f-346b-4a43-87e3-e5d2f56559bd",
            "5bd67481-8812-4061-82db-21b434264cfe",
            "aa764912-79bc-452f-8fe0-c953c0cff29a",
            "4641e4ba-e28f-4f34-aed6-aae79a21fe0c"
          ],
          "display_name": true,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "366e5d56-a189-43b2-8360-a0a7fe713e60",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "ae93f776-646f-4f75-b58d-d5b1e1a17b7b",
          "name": "TRIHYDROXYMETHYLSILANE",
          "stdName": "TRIHYDROXYMETHYLSILANE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a212f80f-346b-4a43-87e3-e5d2f56559bd",
            "4641e4ba-e28f-4f34-aed6-aae79a21fe0c"
          ],
          "display_name": false
        },
        {
          "uuid": "a8b1835f-678a-436f-9a29-0ca5aee09c98",
          "name": "TRIHYDROXYSILANE",
          "stdName": "TRIHYDROXYSILANE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a212f80f-346b-4a43-87e3-e5d2f56559bd",
            "4641e4ba-e28f-4f34-aed6-aae79a21fe0c"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "a212f80f-346b-4a43-87e3-e5d2f56559bd",
          "citation": "PCPC-DB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "4641e4ba-e28f-4f34-aed6-aae79a21fe0c",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "aa764912-79bc-452f-8fe0-c953c0cff29a",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6ba59d74-b50a-4ab0-944c-6231dd9847f3",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391043000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6cc5f06a-97ac-4a2f-b812-e67f23db0b59",
          "citation": "SRS import [E52D0J3TS5]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=E52D0J3TS5",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391043000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1c82412d-a54e-478b-8aba-08487c9e48a0",
          "citation": "CHEMID  2011",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "5bd67481-8812-4061-82db-21b434264cfe",
          "citation": "SILANETRIOL [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "9932a73d-18ed-5596-e28d-80b754afed7e",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=2445-53-6",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "58cb3f74-86b7-48b7-97da-8bf97d49b4b6",
          "citation": "https://www.oleapharma.com/en/Sedifa/CONJONCTYL-filling-skin-depressions-10x5ml-3066.html",
          "url": "https://www.oleapharma.com/en/Sedifa/CONJONCTYL-filling-skin-depressions-10x5ml-3066.html",
          "doc_type": "MANUFACTURER PRODUCT DESCRIPTION",
          "public_domain": true
        },
        {
          "uuid": "e3cfce15-1099-404e-96bb-0940055078cc",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "60d651c2-6d35-b65c-24f6-35a3b2cb5784",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "69f2fc92-3103-3338-d237-d9c76fde138b",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "e69043dc-1f81-f9bb-203f-934c2a018de7",
          "citation": "EU-SRS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "fac79b88-c0e5-427e-bb3f-d6d67f1fe1b5",
          "id": "fac79b88-c0e5-427e-bb3f-d6d67f1fe1b5",
          "molfile": "\n  Marvin  01132112592D          \n\n  5  4  0  0  0  0            999 V2000\n    6.8100   -4.3033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.8100   -5.1283    0.0000 Si  0  0  0  0  0  0  0  0  0  0  0  0\n    6.8100   -5.9533    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.9850   -5.1283    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    7.6349   -5.1283    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  2  3  1  0  0  0  0\n  2  4  1  0  0  0  0\n  2  5  1  0  0  0  0\nM  END",
          "smiles": "C[Si](O)(O)O",
          "formula": "CH6O3Si",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "27b4bc03-8716-40aa-8418-33716ccfb342"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "94.142",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "aaa28520-2073-4a42-91f6-bee1a1895aa2",
      "version": "8",
      "structure": {
        "id": "7c98d64b-1038-4a17-bfaa-6a360b49a7c6",
        "molfile": "\n  Marvin  01132106282D          \n\n  5  4  0  0  0  0            999 V2000\n    6.8100   -5.1283    0.0000 Si  0  0  0  0  0  0  0  0  0  0  0  0\n    6.8100   -5.9533    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.9850   -5.1283    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    7.6349   -5.1283    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.8100   -4.3033    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  1  3  1  0  0  0  0\n  1  4  1  0  0  0  0\n  1  5  1  0  0  0  0\nM  END",
        "smiles": "C[Si](O)(O)O",
        "formula": "CH6O3Si",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "94.142",
        "optical_activity": "NONE",
        "references": [
          "6cc5f06a-97ac-4a2f-b812-e67f23db0b59",
          "1c82412d-a54e-478b-8aba-08487c9e48a0"
        ],
        "stereo_centers": 0
      },
      "unii": "E52D0J3TS5"
    }
  ]
}