{ "meta": { "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.", "terms": "https://open.fda.gov/terms/", "license": "https://open.fda.gov/license/", "last_updated": "2025-09-19", "results": { "skip": 0, "limit": 1, "total": 1 } }, "results": [ { "codes": [ { "uuid": "4c48f5d2-9a54-4580-b43e-09ea986fec7e", "code": "497-76-7", "type": "PRIMARY", "url": "https://commonchemistry.cas.org/detail?cas_rn=497-76-7", "code_system": "CAS", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730", "321c4fd3-2028-4698-8830-a9aff6886e8e" ] }, { "uuid": "950c9f9d-240c-468c-8240-d5908de82c45", "code": "C87429", "type": "PRIMARY", "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C87429", "code_system": "NCI_THESAURUS", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "f953a86a-0008-481d-9e18-dd1e229a3212", "code": "ARBUTIN", "type": "PRIMARY", "url": "https://en.wikipedia.org/wiki/Arbutin", "code_system": "WIKIPEDIA", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "2a34c9ae-9091-4c22-a840-5c8301a6da52", "code": "207-850-3", "type": "PRIMARY", "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.007.138", "code_system": "ECHA (EC/EINECS)", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "9da7c361-82d8-4967-8490-1fda8b4b9c7b", "code": "1367175", "comments": "RxNorm", "type": "PRIMARY", "url": "https://rxnav.nlm.nih.gov/REST/rxcui/1367175/allProperties.xml?prop=all", "code_system": "RXCUI", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "13f35d5d-4ce0-4b57-b8a1-eb995cef8e97", "code": "m2033", "comments": "Merck Index", "type": "PRIMARY", "url": "https://merckindex.rsc.org/monographs/m2033?q=authorize", "code_system": "MERCK INDEX", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "6136a972-da03-4c96-86d0-be60c9fdaf00", "code": "SUB33412", "type": "PRIMARY", "code_system": "EVMPD", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "f783d483-d3b2-4908-85a3-5675fa360dd7", "code": "440936", "type": "PRIMARY", "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440936", "code_system": "PUBCHEM", "references": [ "8d00c778-7e10-454b-984f-bb140dc1e730" ] }, { "uuid": "2bdcf973-2462-d1b2-43ea-522cb35d9d9b", "code": "7661", "type": "PRIMARY", "url": "https://pubchem.ncbi.nlm.nih.gov/source/hsdb/7661", "code_system": "HSDB", "references": [ "4206137e-83f7-892c-d655-1fb0129756bd" ] }, { "uuid": "9818dfbf-2c1d-ae79-ba33-e67bcc811c07", "code": "DTXSID7040152", "type": "PRIMARY", "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID7040152", "code_system": "EPA CompTox", "references": [ "e3e7ef90-3545-613b-6833-58d138b51be4" ] }, { "uuid": "142aef0d-75ba-6fff-4dfc-007a5f48536b", "code": "C471", "comments": "Pharmacologic Substance[C1909]|Enzyme Inhibitor", "type": "CONCEPT", "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C471", "code_system": "NCI_THESAURUS", "references": [ "fa7294a4-8822-764c-2924-8eb0e83778c6" ] }, { "uuid": "dd6d1752-8d47-6684-12f0-1377dcd2633f", "code": "1289 (Number of products:3)", "comments": "Dietary Supplement Label Database|Botanical|Arbutin", "type": "PRIMARY", "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=1289&item=Arbutin", "code_system": "DSLD", "references": [ "fa7294a4-8822-764c-2924-8eb0e83778c6" ] }, { "uuid": "9b921f2d-9d67-afe4-b803-0efd6a17150e", "code": "4267", "type": "PRIMARY", "url": "https://drugcentral.org/drugcard/4267", "code_system": "DRUG CENTRAL", "references": [ "fa7294a4-8822-764c-2924-8eb0e83778c6" ] }, { "uuid": "0a503a80-7b47-77a5-9619-c9c03e922aba", "code": "DB11217", "type": "PRIMARY", "url": "http://www.drugbank.ca/drugs/DB11217", "code_system": "DRUG BANK", "references": [ "fa7294a4-8822-764c-2924-8eb0e83778c6" ] }, { "uuid": "3a85e13c-74f2-4d66-aef2-c0197e0c0913", "code": "C5INA23HXF", "type": "PRIMARY", "code_system": "FDA UNII" }, { "uuid": "9a7af326-266f-ab1f-3af5-a472de18dd70", "code": "18305", "type": "PRIMARY", "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:18305", "code_system": "CHEBI", "references": [ "fa7294a4-8822-764c-2924-8eb0e83778c6" ] }, { "uuid": "9d43f431-7119-4c0c-2f72-47b5d700cd80", "code": "100000126183", "type": "PRIMARY", "code_system": "SMS_ID", "references": [ "b5a00fa2-0fc1-83f3-3538-ff308c902e9b" ] }, { "uuid": "ed2a5ba3-b0ed-b6df-06dc-172d3296306b", "code": "4036", "type": "PRIMARY", "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=4036", "code_system": "NSC", "references": [ "783f4a68-8867-27a0-2eee-4766c324d6bb" ] }, { "uuid": "6bfe86cb-916d-e1a0-9258-ad6a9620fe6d", "code": "C5INA23HXF", "type": "PRIMARY", "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=C5INA23HXF", "code_system": "DAILYMED", "references": [ "4099c245-d8ba-698d-9240-17e70b4639e3" ] } ], "relationships": [ { "uuid": "ed0635c6-3d2b-4e32-b321-1b99e14f2d56", "type": "ACTIVE MOIETY", "related_substance": { "uuid": "37a5c69a-796a-4c5b-a13d-bb636d989c6d", "refuuid": "06b69e18-3087-441c-8944-727188242c81", "name": "ARBUTIN", "unii": "C5INA23HXF", "linking_id": "C5INA23HXF", "ref_pname": "ARBUTIN", "substance_class": "reference" } }, { "uuid": "7ec50ade-9c8c-4d09-bc30-ca87b844f79c", "amount": { "uuid": "0c2a01d1-2d76-451e-b4d6-a0b6a6d2f516", "type": "RELATIONSHIP_AMOUNT", "average": 224.5, "units": "MICROMOLAR" }, "comments": "945mg bear berry leaf extract (w/210mg arbutin) single oral administration, 0-4hr urine, n=1", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "816ee220-3848-461b-a0db-dc0b167f91f3" ], "related_substance": { "uuid": "42d48e93-b44d-4684-8fcf-9d45951bb061", "refuuid": "edf36d4b-b224-41bc-8fc0-696d1266cd3f", "name": "QUINOL GLUCURONIDE", "unii": "7UQ83N5MHX", "linking_id": "7UQ83N5MHX", "ref_pname": "QUINOL GLUCURONIDE", "substance_class": "reference" } }, { "uuid": "b4ee3651-57f7-4e8c-86a5-4a4fda7c6f9c", "amount": { "uuid": "7cfcfc3d-e63b-4788-8241-581cd345fb07", "type": "RELATIONSHIP_AMOUNT", "average": 100.53, "units": "MG" }, "comments": "Unit: mg; Amount excreted in urine within 36-hr study period, Bearberry leaves dry extract(BLDE) 945mg single oral administration(210mg arbutin correspondence, aqueous solution), n=16 (8 female & 8 male)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "e2dfa15b-0f0a-4697-a500-cd267f3a45db" ], "related_substance": { "uuid": "dd56655e-92d1-4051-bebf-1ad6af98f204", "refuuid": "edf36d4b-b224-41bc-8fc0-696d1266cd3f", "name": "QUINOL GLUCURONIDE", "unii": "7UQ83N5MHX", "linking_id": "7UQ83N5MHX", "ref_pname": "QUINOL GLUCURONIDE", "substance_class": "reference" } }, { "uuid": "3a53a8ac-53c7-4011-8197-6fc209c934c7", "amount": { "uuid": "66cff1d9-cb96-49dc-8e33-faae414efe29", "type": "RELATIONSHIP_AMOUNT", "average": 99.06, "units": "MG" }, "comments": "Unit: mg; Amount excreted in urine within 36-hr study period, Bearberry leaves dry extract(BLDE) 945mg single oral administration(210mg arbutin correspondence, in 2 film coated tabs, each contained 472.5mg BLDE or 105mg arbutin), n=16 (8 female & 8 male)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "e2dfa15b-0f0a-4697-a500-cd267f3a45db" ], "related_substance": { "uuid": "1c57b006-52b8-4d6d-9dd6-137d7187768f", "refuuid": "edf36d4b-b224-41bc-8fc0-696d1266cd3f", "name": "QUINOL GLUCURONIDE", "unii": "7UQ83N5MHX", "linking_id": "7UQ83N5MHX", "ref_pname": "QUINOL GLUCURONIDE", "substance_class": "reference" } }, { "uuid": "de4e6dfe-3606-4aec-b1fa-f296d0002f1c", "amount": { "uuid": "e5bfb9c7-d583-46d9-a55a-9ddd84c908b6", "type": "RELATIONSHIP_AMOUNT", "units": "MG", "high_limit": 110, "low_limit": 80 }, "comments": "Unit: mg calculated as arbutin; Urinary elimination of arbutin metabolites (16-24hr urine, n=3, 150mg arubutin in about 150mL aqueous bearberry leaf extract, q.i.d.)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "bcd4086d-0c29-4892-ac49-6130eb77c743" ], "related_substance": { "uuid": "dbc78be8-9f2e-475f-9393-82f5987e5c1a", "refuuid": "edf36d4b-b224-41bc-8fc0-696d1266cd3f", "name": "QUINOL GLUCURONIDE", "unii": "7UQ83N5MHX", "linking_id": "7UQ83N5MHX", "ref_pname": "QUINOL GLUCURONIDE", "substance_class": "reference" } }, { "uuid": "2c303ad0-b16c-498d-aa10-45acacc89c23", "amount": { "uuid": "5fd458cb-e021-4ccf-a927-acfdb77c2eb8", "type": "RELATIONSHIP_AMOUNT", "average": 28.04, "units": "MG" }, "comments": "Amount excreted in urine within the 36-hour period, 945mg bearberry leaf dry extract (210mg arbutin equivalent, in aqueous solution) single oral administration, n=16 (8 female, 8 male)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "d5616cb9-d154-42a3-90e7-f8ef39d8dd04" ], "related_substance": { "uuid": "0a97e7dd-8d59-4fef-a13a-ea4ecc8369ac", "refuuid": "ea9de1d5-85c7-416b-9ed8-26b71bdb4258", "name": "HYDROQUINONE MONOSULFATE", "unii": "P938AXP4T2", "linking_id": "P938AXP4T2", "ref_pname": "HYDROQUINONE MONOSULFATE", "substance_class": "reference" } }, { "uuid": "be45cfc1-0319-4878-9088-698bc49fed2c", "amount": { "uuid": "0fc3c25b-437d-4d62-8b6e-148f8c0d86fb", "type": "RELATIONSHIP_AMOUNT", "average": 32.25, "units": "MG" }, "comments": "Amount excreted in urine within the 36-hour period, 945mg bearberry leaf dry extract (210mg arbutin equivalent, in two film coated tabs) single oral administration, n=16 (8 female, 8 male)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "d5616cb9-d154-42a3-90e7-f8ef39d8dd04" ], "related_substance": { "uuid": "7003b536-75cb-4079-8258-de92f01499fa", "refuuid": "ea9de1d5-85c7-416b-9ed8-26b71bdb4258", "name": "HYDROQUINONE MONOSULFATE", "unii": "P938AXP4T2", "linking_id": "P938AXP4T2", "ref_pname": "HYDROQUINONE MONOSULFATE", "substance_class": "reference" } }, { "uuid": "055bcd16-4956-49aa-8ee8-9bc12fb6d48e", "amount": { "uuid": "f670d7e6-8791-4646-b4d8-3cbbf21de985", "type": "RELATIONSHIP_AMOUNT", "units": "MG", "high_limit": 95, "low_limit": 60 }, "comments": "Unit: mg (calculated as arbutin); Urinary elimination profiles of arbutin metabolites (150mg arbutin in about 150mL aqueous bearberry leaf extract oral q.i.d., n=3, 16-24hr urine)", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "bcd4086d-0c29-4892-ac49-6130eb77c743" ], "related_substance": { "uuid": "327b0603-a933-417b-a5f9-3e7fd34695fe", "refuuid": "ea9de1d5-85c7-416b-9ed8-26b71bdb4258", "name": "HYDROQUINONE MONOSULFATE", "unii": "P938AXP4T2", "linking_id": "P938AXP4T2", "ref_pname": "HYDROQUINONE MONOSULFATE", "substance_class": "reference" } }, { "uuid": "f43965c7-09c6-4c0b-a742-5fd4bac504c4", "amount": { "uuid": "94b4e7ea-22c6-4920-9f20-776f47e582f4" }, "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "related_substance": { "uuid": "6d58e26f-e8d2-44fa-a72e-91b049543e3a", "refuuid": "7279e9c1-1bb7-45b5-af53-5ec8448d843b", "name": "Hydroquinone", "unii": "XV74C1N1AE", "linking_id": "XV74C1N1AE", "ref_pname": "Hydroquinone", "substance_class": "reference" } }, { "uuid": "1c38c1b2-a66c-45fa-97e9-b537984db461", "amount": { "uuid": "a9034a49-85f2-4e93-88e3-3bbc8a09bae7", "type": "RELATIONSHIP_AMOUNT", "average": 0.06, "units": "MG" }, "comments": "Amount excreted in urine within the 36-hour study period, 945mg bearberry leaf extract (corresponding to 210mg arbutin, in two film coated tabs) single oral administration, n=16 (8 female, 8 male), 0-36hr urine", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "d5616cb9-d154-42a3-90e7-f8ef39d8dd04" ], "related_substance": { "uuid": "5827178e-27d8-4a93-82b2-22e9457aed9a", "refuuid": "7279e9c1-1bb7-45b5-af53-5ec8448d843b", "name": "Hydroquinone", "unii": "XV74C1N1AE", "linking_id": "XV74C1N1AE", "ref_pname": "Hydroquinone", "substance_class": "reference" } }, { "uuid": "17755f23-f272-461a-bce1-0f3a724b4281", "amount": { "uuid": "faa8169c-4757-4da0-bd44-cd5010065e1a", "type": "RELATIONSHIP_AMOUNT", "units": "MG", "high_limit": 33.9, "low_limit": 0.3 }, "comments": "Unit: mg (calculated as arbutin); 150mg arbutin in about 150mL aqueous bearberry leaf extract, q.i.d.; 0-24hr urine; n=3", "qualification": "URINE", "type": "METABOLITE->PARENT", "interaction_type": "IN-VIVO", "references": [ "867676b4-736f-4c86-a643-0def9961995f" ], "related_substance": { "uuid": "3994ae31-169c-4e3f-bffe-262a6890383e", "refuuid": "7279e9c1-1bb7-45b5-af53-5ec8448d843b", "name": "Hydroquinone", "unii": "XV74C1N1AE", "linking_id": "XV74C1N1AE", "ref_pname": "Hydroquinone", "substance_class": "reference" } } ], "substance_class": "chemical", "names": [ { "uuid": "94f475a7-e3db-4a10-a7c1-9974afd211a2", "name": "4-HYDROXYPHENYL-.BETA.-D-GLUCOPYRANOSIDE", "stdName": "4-HYDROXYPHENYL-.BETA.-D-GLUCOPYRANOSIDE", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false }, { "uuid": "8d737018-3210-41e8-8782-6b34b09b7f28", "name": "ARBUTIN", "stdName": "ARBUTIN", "type": "of", "languages": [ "en" ], "preferred": false, "references": [ "bf158e4a-4cbc-4d38-ac1e-18d2b2c8ad89", "343daa1b-238e-44eb-9780-038ce5bf00c4", "69fb1152-103c-412b-9b23-e5f7b4311841", "b8d22025-2987-4d7d-afba-9a812cf4c26f", "a27ab7f8-69a1-4310-ae2c-651f9a77388e", "3a961488-c293-4e79-ad4e-b27c61e8ec50", "a7b3c96b-881a-4a86-990e-f2d792beda57", "111a4ef3-1693-4aee-96e4-172f7d73beeb", "1538eef0-01e5-4047-b37e-5b7c8a0c5077", "144b30ee-bd1b-42b6-b538-5b0337860dbf", "dba8de9a-ce6d-4011-8dfd-2ee3d7930062", "fb977894-c7b0-45b3-9e77-9ca6a3875e32" ], "display_name": true, "domains": [ "cosmetic" ], "name_orgs": [ { "uuid": "902ce929-cca7-4814-a87a-78db34cbf17b", "name_org": "INCI" } ] }, { "uuid": "1281415d-4357-43af-8a39-a9a46828e419", "name": "ARBUTIN [HSDB]", "stdName": "ARBUTIN [HSDB]", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "a7b3c96b-881a-4a86-990e-f2d792beda57", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false }, { "uuid": "d7ecb289-4798-43d6-a99d-aae20740dae0", "name": "ARBUTIN [MART.]", "stdName": "ARBUTIN [MART.]", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "69fb1152-103c-412b-9b23-e5f7b4311841" ], "display_name": false }, { "uuid": "5043661b-c799-4b79-a417-f715837da298", "name": "ARBUTIN [MI]", "stdName": "ARBUTIN [MI]", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "1538eef0-01e5-4047-b37e-5b7c8a0c5077", "dba8de9a-ce6d-4011-8dfd-2ee3d7930062" ], "display_name": false }, { "uuid": "fec1f9ca-d7a0-49da-b0ed-2ec0f57924be", "name": "ARBUTINUM", "stdName": "ARBUTINUM", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "1538eef0-01e5-4047-b37e-5b7c8a0c5077", "678ee547-8033-44ab-8205-a38e2c29234d", "79037ef9-ea34-4c20-9aaf-9c21cac90a4c", "1d5d14d7-5d3a-4641-a4b4-5f3ab6e48229" ], "display_name": false }, { "uuid": "096c8933-d9ac-42ca-acd3-5ed6bb186c20", "name": "ARBUTINUM [HPUS]", "stdName": "ARBUTINUM [HPUS]", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "678ee547-8033-44ab-8205-a38e2c29234d", "79037ef9-ea34-4c20-9aaf-9c21cac90a4c" ], "display_name": false }, { "uuid": "9239dde9-7eae-4ada-be55-f4aa49df423e", "name": "ARBUTOSIDE", "stdName": "ARBUTOSIDE", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false }, { "uuid": "150955fe-96a8-73f8-8919-74b77e093444", "name": "Arbutin [WHO-DD]", "stdName": "ARBUTIN [WHO-DD]", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "86cecc84-1213-77d0-25be-f4a6ccf7e045" ], "display_name": false }, { "uuid": "2d50366b-bab0-46a2-949d-0b00ae89ae77", "name": "HYDROQUINONE GLUCOSE", "stdName": "HYDROQUINONE GLUCOSE", "type": "sys", "languages": [ "en" ], "preferred": false, "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false }, { "uuid": "6fc41694-0f82-4494-9ec1-2798d348f983", "name": "HYDROQUINONE-.BETA.-D-GLUCOPYRANOSIDE", "stdName": "HYDROQUINONE-.BETA.-D-GLUCOPYRANOSIDE", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false }, { "uuid": "a1772eef-ee0f-4cd7-b5c1-7beb7673541c", "name": "NSC-4036", "stdName": "NSC-4036", "type": "cd", "languages": [ "en" ], "preferred": false, "references": [ "1538eef0-01e5-4047-b37e-5b7c8a0c5077", "88da5031-cc24-4b75-8be9-75737631c656" ], "display_name": false }, { "uuid": "f5990288-eb11-473d-9f75-af78e10e03fe", "name": "URSIN", "stdName": "URSIN", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "1538eef0-01e5-4047-b37e-5b7c8a0c5077" ], "display_name": false } ], "references": [ { "uuid": "678ee547-8033-44ab-8205-a38e2c29234d", "citation": "HPUS", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN", "PUBLIC_DOMAIN_RELEASE", "AUTO_SELECTED" ] }, { "uuid": "1538eef0-01e5-4047-b37e-5b7c8a0c5077", "citation": "HOMEOPATHIC PHARMACOPOEIA US", "doc_type": "HOMEOPATHIC PHARMACOPOEIA US", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "144b30ee-bd1b-42b6-b538-5b0337860dbf", "citation": "USP DICTIONARY 2009", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "50d2432b-1631-4561-9cb8-0e56015ffaf8", "citation": "MERCK", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "79037ef9-ea34-4c20-9aaf-9c21cac90a4c", "citation": "HPUS 2011", "doc_type": "HOMEOPATHIC PHARMACOPOEIA US", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "69fb1152-103c-412b-9b23-e5f7b4311841", "citation": "MARTINDALE 2011", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "dba8de9a-ce6d-4011-8dfd-2ee3d7930062", "citation": "MERCK INDEX", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "fb977894-c7b0-45b3-9e77-9ca6a3875e32", "citation": "PCPC", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "a7b3c96b-881a-4a86-990e-f2d792beda57", "citation": "HSDB", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "bf158e4a-4cbc-4d38-ac1e-18d2b2c8ad89", "citation": "WHO-DD", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "88da5031-cc24-4b75-8be9-75737631c656", "citation": "CHEMID", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "8d00c778-7e10-454b-984f-bb140dc1e730", "citation": "SRS CODE IMPORT", "doc_type": "SRS", "public_domain": true, "document_date": 1493389718000, "tags": [ "NOMEN" ] }, { "uuid": "816ee220-3848-461b-a0db-dc0b167f91f3", "citation": "J CHROMATOGR B 761 261 (2001)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=j+chromatogr+b+761+261+2001", "doc_type": "JOURNAL ARTICLE", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "e2dfa15b-0f0a-4697-a500-cd267f3a45db", "citation": "J CLIN PHARMACOL 42 920 (2002)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=12162475", "doc_type": "JOURNAL ARTICLE", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "bcd4086d-0c29-4892-ac49-6130eb77c743", "citation": "PLANTA MED 71 147 (2005)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=15729623", "doc_type": "JOURNAL ARTICLE", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "d5616cb9-d154-42a3-90e7-f8ef39d8dd04", "citation": "J CLIN PHARMACOL 42 920 (2002)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=j+clin+pharmacol+42+920+2002", "doc_type": "JOURNAL ARTICLE", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "867676b4-736f-4c86-a643-0def9961995f", "citation": "PLANTA MED 71 147 (2005)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/?term=planta+med+71+147+2005", "doc_type": "JOURNAL ARTICLE", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "5da618e9-dc2f-407d-8717-b7bebfcfea45", "citation": "SRS import [C5INA23HXF]", "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=C5INA23HXF", "doc_type": "SRS", "public_domain": true, "document_date": 1493389718000, "tags": [ "NOMEN" ] }, { "uuid": "1d5d14d7-5d3a-4641-a4b4-5f3ab6e48229", "citation": "ARBUTINUM [HPUS]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "3a961488-c293-4e79-ad4e-b27c61e8ec50", "citation": "ARBUTIN [MART.]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "a27ab7f8-69a1-4310-ae2c-651f9a77388e", "citation": "ARBUTIN [MI]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "343daa1b-238e-44eb-9780-038ce5bf00c4", "citation": "ARBUTIN [INCI]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "111a4ef3-1693-4aee-96e4-172f7d73beeb", "citation": "ARBUTIN [HSDB]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "b8d22025-2987-4d7d-afba-9a812cf4c26f", "citation": "ARBUTIN [WHO-DD]", "doc_type": "SRS_LOCATOR", "public_domain": true }, { "uuid": "4206137e-83f7-892c-d655-1fb0129756bd", "citation": "WEBSITE", "url": "https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+497-76-7", "doc_type": "WEBSITE", "public_domain": true, "tags": [ "NOMEN", "PUBLIC_DOMAIN_RELEASE" ] }, { "uuid": "e3e7ef90-3545-613b-6833-58d138b51be4", "citation": "WEBSITE", "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=497-76-7", "doc_type": "WEBSITE", "public_domain": true, "tags": [ "NOMEN", "PUBLIC_DOMAIN_RELEASE" ] }, { "uuid": "fa7294a4-8822-764c-2924-8eb0e83778c6", "doc_type": "SYSTEM", "public_domain": true }, { "uuid": "321c4fd3-2028-4698-8830-a9aff6886e8e", "citation": "STN", "doc_type": "STN (SCIFINDER)", "public_domain": true }, { "uuid": "783f4a68-8867-27a0-2eee-4766c324d6bb", "citation": "NCI", "doc_type": "NCI DRUG DICTIONARY", "public_domain": true }, { "uuid": "4099c245-d8ba-698d-9240-17e70b4639e3", "citation": "DailyMed", "doc_type": "DAILYMED", "public_domain": true }, { "uuid": "86cecc84-1213-77d0-25be-f4a6ccf7e045", "citation": "WHO-DD", "doc_type": "WHO DRUG DICTIONARY", "public_domain": true }, { "uuid": "b5a00fa2-0fc1-83f3-3538-ff308c902e9b", "citation": "EU-SRS", "doc_type": "EMA LIST", "public_domain": true } ], "definition_type": "PRIMARY", "moieties": [ { "uuid": "613420cc-ad01-4bc9-8f72-c682c89fcd7f", "id": "613420cc-ad01-4bc9-8f72-c682c89fcd7f", "molfile": "\n Marvin 01132105022D \n\n 19 20 0 0 1 0 999 V2000\n 8.2723 -10.3300 0.0000 C 0 0 1 0 0 0 0 0 0 1 0 0\n 7.8691 -9.6067 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.0585 -9.7564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 9.1037 -10.3300 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 9.5152 -11.0533 0.0000 C 0 0 1 0 0 0 0 0 0 2 0 0\n 10.3383 -11.0533 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 11.1614 -11.0533 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.5646 -10.3425 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 12.3835 -10.3300 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 12.7992 -11.0491 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 13.6223 -11.0491 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 12.3877 -11.7642 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.5646 -11.7642 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 9.0954 -11.7642 0.0000 C 0 0 2 0 0 0 0 0 0 1 0 0\n 9.5028 -12.4833 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 8.2681 -11.7600 0.0000 C 0 0 1 0 0 0 0 0 0 2 0 0\n 7.8483 -12.4750 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 7.8608 -11.0409 0.0000 C 0 0 2 0 0 0 0 0 0 2 0 0\n 7.0335 -11.0409 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 1 2 1 1 0 0 0\n 1 4 1 0 0 0 0\n 18 1 1 0 0 0 0\n 3 2 1 0 0 0 0\n 5 4 1 0 0 0 0\n 5 6 1 1 0 0 0\n 14 5 1 0 0 0 0\n 7 6 1 0 0 0 0\n 8 7 1 0 0 0 0\n 13 7 2 0 0 0 0\n 9 8 2 0 0 0 0\n 10 9 1 0 0 0 0\n 11 10 1 0 0 0 0\n 12 10 2 0 0 0 0\n 12 13 1 0 0 0 0\n 14 15 1 6 0 0 0\n 14 16 1 0 0 0 0\n 16 17 1 1 0 0 0\n 16 18 1 0 0 0 0\n 18 19 1 6 0 0 0\nM END", "smiles": "c1cc(ccc1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O", "formula": "C12H16O7", "atropisomerism": "No", "charge": 0, "count": 1, "stereochemistry": "ABSOLUTE", "count_amount": { "type": "MOL RATIO", "average": 1, "units": "MOL RATIO", "uuid": "2c8ca0b0-69d2-42f0-b55b-b4a107c8d1c2" }, "defined_stereo": 5, "ez_centers": 0, "molecular_weight": "272.2517", "optical_activity": "UNSPECIFIED", "stereo_centers": 5 } ], "definition_level": "COMPLETE", "uuid": "06b69e18-3087-441c-8944-727188242c81", "version": "17", "structure": { "id": "bcf8b019-f999-4cda-8456-26d2145e15bb", "molfile": "\n Marvin 01132109462D \n\n 19 20 0 0 1 0 999 V2000\n 9.5152 -11.0533 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0\n 9.0954 -11.7642 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0\n 8.2681 -11.7600 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0\n 9.1037 -10.3300 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 7.8608 -11.0409 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0\n 8.2723 -10.3300 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0\n 10.3383 -11.0533 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 9.5028 -12.4833 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 7.8483 -12.4750 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 11.1614 -11.0533 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.0335 -11.0409 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 12.7992 -11.0491 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.8691 -9.6067 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.5646 -11.7642 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.5646 -10.3425 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 12.3835 -10.3300 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 12.3877 -11.7642 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 13.6223 -11.0491 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 7.0585 -9.7564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 2 1 1 0 0 0 0\n 3 2 1 0 0 0 0\n 4 1 1 0 0 0 0\n 5 6 1 0 0 0 0\n 6 4 1 0 0 0 0\n 1 7 1 1 0 0 0\n 2 8 1 6 0 0 0\n 3 9 1 1 0 0 0\n 10 7 1 0 0 0 0\n 5 11 1 6 0 0 0\n 12 16 1 0 0 0 0\n 6 13 1 1 0 0 0\n 14 10 2 0 0 0 0\n 15 10 1 0 0 0 0\n 16 15 2 0 0 0 0\n 17 14 1 0 0 0 0\n 18 12 1 0 0 0 0\n 19 13 1 0 0 0 0\n 3 5 1 0 0 0 0\n 17 12 2 0 0 0 0\nM END", "smiles": "c1cc(ccc1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O", "formula": "C12H16O7", "atropisomerism": "No", "charge": 0, "count": 1, "stereochemistry": "ABSOLUTE", "defined_stereo": 5, "ez_centers": 0, "molecular_weight": "272.2517", "optical_activity": "UNSPECIFIED", "references": [ "50d2432b-1631-4561-9cb8-0e56015ffaf8", "5da618e9-dc2f-407d-8717-b7bebfcfea45" ], "stereo_centers": 5 }, "unii": "C5INA23HXF" } ] }