{ "meta": { "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.", "terms": "https://open.fda.gov/terms/", "license": "https://open.fda.gov/license/", "last_updated": "2025-09-19", "results": { "skip": 0, "limit": 1, "total": 1 } }, "results": [ { "codes": [ { "uuid": "8adaedfb-910b-4c29-acf8-d7f9508de2c7", "code": "99519-84-3", "type": "PRIMARY", "url": "https://commonchemistry.cas.org/detail?cas_rn=99519-84-3", "code_system": "CAS", "references": [ "b0a58124-16d0-4b2b-8da8-2b38fb296fa0", "6d9a3691-ce33-4c7c-82d9-751ef5040ca2" ] }, { "uuid": "0b041da5-7352-4ef7-8b05-59ee94b23419", "code": "CARBOXYAMIDOTRIAZOLE", "type": "PRIMARY", "url": "https://en.wikipedia.org/wiki/Carboxyamidotriazole", "code_system": "WIKIPEDIA", "references": [ "b0a58124-16d0-4b2b-8da8-2b38fb296fa0" ] }, { "uuid": "75f403df-1907-4179-aec7-5d29f8f9114e", "code": "108144", "type": "PRIMARY", "url": "https://pubchem.ncbi.nlm.nih.gov/compound/108144", "code_system": "PUBCHEM", "references": [ "b0a58124-16d0-4b2b-8da8-2b38fb296fa0" ] }, { "uuid": "78d25e1d-cbc9-14eb-d431-8a71ca1661f1", "code": "DTXSID40244108", "type": "PRIMARY", "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID40244108", "code_system": "EPA CompTox", "references": [ "2ee45310-c600-3ab0-c6c7-80bb9e910ad9" ] }, { "uuid": "a804a10a-7222-615c-afde-373468bb35a1", "code": "C1971", "comments": "Pharmacologic Substance[C1909]|Antineoplastic Agent[C274]|Angiogenesis Inhibitor[C1742]|Angiogenesis Activator Inhibitor", "codeText": "Pharmacologic Substance[C1909]|Antineoplastic Agent[C274]|Angiogenesis Inhibitor[C1742]|Angiogenesis Activator Inhibitor", "type": "CONCEPT", "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1971", "code_system": "NCI_THESAURUS" }, { "uuid": "ee5e3859-3205-1108-a3fe-9685056036e1", "code": "C333", "comments": "Pharmacologic Substance[C1909]|Cation Channel Blocker[C93038]|Calcium Channel Blocker", "type": "CONCEPT", "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C333", "code_system": "NCI_THESAURUS" }, { "uuid": "03c3c28f-b776-48b9-86e6-7aa22bcf1b34", "code": "6ST3ZF52WB", "type": "PRIMARY", "code_system": "FDA UNII" }, { "uuid": "ccdd7b69-78a7-a435-11f8-4310b66c1752", "code": "DB11960", "type": "PRIMARY", "url": "http://www.drugbank.ca/drugs/DB11960", "code_system": "DRUG BANK" }, { "uuid": "f7663f73-6188-a85b-be6f-110ca94218ae", "code": "C1141", "type": "PRIMARY", "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1141", "code_system": "NCI_THESAURUS", "references": [ "5aeef13b-62ef-7ad0-9c7d-1de1080f41ee" ] }, { "uuid": "399629b5-6ad1-c6ba-26c0-90f0b88430e1", "code": "100000178003", "type": "PRIMARY", "code_system": "SMS_ID", "references": [ "044af037-717e-68af-a452-6d43cb356eaf" ] }, { "uuid": "1804e3ab-97be-0282-e0a2-f9ff3f5c2acb", "code": "609974", "type": "PRIMARY", "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=609974", "code_system": "NSC", "references": [ "0dc1c11c-9b73-9aba-f16a-ff3d63df200a" ] } ], "relationships": [ { "uuid": "7ea6f556-c09c-4504-a97c-9a0f2d2baed4", "qualification": "PLASMA; URINE", "type": "METABOLITE->PARENT", "references": [ "a15ae006-b7f5-491a-986c-ece823a32cee" ], "related_substance": { "uuid": "397d2f52-3373-4049-a3eb-c8be08146226", "refuuid": "a16288ae-c7c3-4b2e-bae2-3696e5e6e738", "name": "3,5-DICHLORO-4-(4-CHLOROBENZOYL)BENZOIC ACID", "unii": "MO2XS2KWL4", "linking_id": "MO2XS2KWL4", "ref_pname": "3,5-DICHLORO-4-(4-CHLOROBENZOYL)BENZOIC ACID" } } ], "substance_class": "chemical", "names": [ { "uuid": "0a59a1c8-1dd6-4570-888f-c33792af7629", "name": "5-AMINO-1-((3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL)METHYL)-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE", "stdName": "5-AMINO-1-((3,5-DICHLORO-4-(4-CHLOROBENZOYL)PHENYL)METHYL)-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE", "type": "sys", "languages": [ "en" ], "preferred": false, "references": [ "df30a1bc-fc12-4726-82c4-560617eaef0c" ], "display_name": false }, { "uuid": "65e45d8e-ca47-499a-9681-eefbeaef5ec2", "name": "CAI", "stdName": "CAI", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "288ffebc-632a-4d76-b31d-e064229ccacd", "bc082076-4958-4917-8e80-58805586ecf0" ], "display_name": false }, { "uuid": "2c127b89-ce93-4a93-a1f2-ba6aa860d766", "name": "CARBOXYAMIDOTRIAZOLE", "stdName": "CARBOXYAMIDOTRIAZOLE", "type": "cn", "languages": [ "en" ], "preferred": false, "references": [ "288ffebc-632a-4d76-b31d-e064229ccacd", "bc082076-4958-4917-8e80-58805586ecf0" ], "display_name": true }, { "uuid": "192e7205-3e6b-48f1-9634-590d49b99100", "name": "L 651582", "stdName": "L 651582", "type": "cd", "languages": [ "en" ], "preferred": false, "references": [ "288ffebc-632a-4d76-b31d-e064229ccacd", "bc082076-4958-4917-8e80-58805586ecf0" ], "display_name": false }, { "uuid": "e1fd677f-bfb5-45f9-abe7-0d43563d94a4", "name": "NSC-609974", "stdName": "NSC-609974", "type": "cd", "languages": [ "en" ], "preferred": false, "references": [ "bc082076-4958-4917-8e80-58805586ecf0", "df30a1bc-fc12-4726-82c4-560617eaef0c" ], "display_name": false } ], "references": [ { "uuid": "df30a1bc-fc12-4726-82c4-560617eaef0c", "citation": "STN", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN", "PUBLIC_DOMAIN_RELEASE", "AUTO_SELECTED" ] }, { "uuid": "bc082076-4958-4917-8e80-58805586ecf0", "citation": "STN (SCIFINDER)", "doc_type": "STN (SCIFINDER)", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "288ffebc-632a-4d76-b31d-e064229ccacd", "citation": "stn", "doc_type": "SRS", "public_domain": true, "tags": [ "NOMEN" ] }, { "uuid": "b0a58124-16d0-4b2b-8da8-2b38fb296fa0", "citation": "SRS CODE IMPORT", "doc_type": "SRS", "public_domain": true, "document_date": 1493390008000, "tags": [ "NOMEN" ] }, { "uuid": "f85256d3-3c87-4d6c-beef-cf350d53ef1e", "citation": "SRS import [6ST3ZF52WB]", "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=6ST3ZF52WB", "doc_type": "SRS", "public_domain": true, "document_date": 1493390008000, "tags": [ "NOMEN" ] }, { "uuid": "2ee45310-c600-3ab0-c6c7-80bb9e910ad9", "citation": "WEBSITE", "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=99519-84-3", "doc_type": "WEBSITE", "public_domain": true, "tags": [ "NOMEN", "PUBLIC_DOMAIN_RELEASE" ] }, { "uuid": "044af037-717e-68af-a452-6d43cb356eaf", "citation": "EU-SRS", "doc_type": "EMA LIST", "public_domain": true }, { "uuid": "a15ae006-b7f5-491a-986c-ece823a32cee", "citation": "Soltis, Mathew J., et al. \"Identification and characterization of human metabolites of CAI [5-amino-1-1 (4'-chlorobenzoyl-3, 5-dichlorobenzyl)-1, 2, 3-triazole-4-carboxamide.\" Drug metabolism and disposition 24.7 (1996): 799-806.", "url": "https://dmd.aspetjournals.org/content/dmd/24/7/799.full.pdf", "doc_type": "JA", "public_domain": true, "tags": [ "PUBLIC_DOMAIN_RELEASE" ] }, { "uuid": "5aeef13b-62ef-7ad0-9c7d-1de1080f41ee", "citation": "NCIT", "doc_type": "NCI THESAURUS", "public_domain": true }, { "uuid": "6d9a3691-ce33-4c7c-82d9-751ef5040ca2", "citation": "STN", "doc_type": "STN (SCIFINDER)", "public_domain": true }, { "uuid": "0dc1c11c-9b73-9aba-f16a-ff3d63df200a", "citation": "NCI", "doc_type": "NCI DRUG DICTIONARY", "public_domain": true } ], "definition_type": "PRIMARY", "moieties": [ { "uuid": "b86c20da-c928-4016-b1cd-dbb560bac728", "id": "b86c20da-c928-4016-b1cd-dbb560bac728", "molfile": "\n Marvin 01132109322D \n\n 27 29 0 0 0 0 999 V2000\n 0.0000 -1.0177 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 0.8136 -0.8217 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 1.0661 0.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 1.4044 -1.4366 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2.4920 -1.4366 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 3.0318 -2.0087 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 2.4517 -2.5807 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 2.9271 -3.3218 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 3.7220 -3.3218 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.1355 -4.0468 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.9492 -4.0468 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3438 -4.7693 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3680 -3.3460 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.2381 -3.3460 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.6141 -4.0468 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 6.6705 -2.6612 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.2623 -1.9443 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.7349 -1.2433 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.5566 -1.2433 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.9863 -0.5425 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 7.9622 -1.9845 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.5244 -2.6612 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.9653 -2.6182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3599 -1.8852 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 4.1516 -2.6182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 1.4044 -2.5807 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 0.8136 -3.1929 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 1 2 1 0 0 0 0\n 3 2 2 0 0 0 0\n 2 4 1 0 0 0 0\n 5 4 1 0 0 0 0\n 26 4 2 0 0 0 0\n 6 5 2 0 0 0 0\n 6 7 1 0 0 0 0\n 8 7 1 0 0 0 0\n 7 26 1 0 0 0 0\n 9 8 1 0 0 0 0\n 10 9 1 0 0 0 0\n 25 9 2 0 0 0 0\n 11 10 2 0 0 0 0\n 12 11 1 0 0 0 0\n 13 11 1 0 0 0 0\n 14 13 1 0 0 0 0\n 23 13 2 0 0 0 0\n 15 14 2 0 0 0 0\n 16 14 1 0 0 0 0\n 17 16 1 0 0 0 0\n 22 16 2 0 0 0 0\n 18 17 2 0 0 0 0\n 18 19 1 0 0 0 0\n 20 19 1 0 0 0 0\n 19 21 2 0 0 0 0\n 21 22 1 0 0 0 0\n 24 23 1 0 0 0 0\n 23 25 1 0 0 0 0\n 27 26 1 0 0 0 0\nM END", "smiles": "c1cc(ccc1C(=O)c2c(cc(cc2Cl)Cn3c(c(C(=O)N)nn3)N)Cl)Cl", "formula": "C17H12Cl3N5O2", "atropisomerism": "No", "charge": 0, "count": 1, "stereochemistry": "ACHIRAL", "count_amount": { "type": "MOL RATIO", "average": 1, "units": "MOL RATIO", "uuid": "d53c62e3-90d8-4f6d-8f83-a650846e2bc7" }, "defined_stereo": 0, "ez_centers": 0, "molecular_weight": "424.6689", "optical_activity": "NONE", "stereo_centers": 0 } ], "definition_level": "COMPLETE", "uuid": "cd87c2fc-8fc9-4f96-8be7-88fbbaa79814", "version": "11", "structure": { "id": "595ffe65-5ece-475e-bebb-482dddb36abb", "molfile": "\n Marvin 01132104382D \n\n 27 29 0 0 0 0 999 V2000\n 1.4044 -1.4366 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 1.4044 -2.5807 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2.4517 -2.5807 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 3.0318 -2.0087 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 2.4920 -1.4366 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3680 -3.3460 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.9492 -4.0468 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.9653 -2.6182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.2381 -3.3460 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 0.8136 -0.8217 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2.9271 -3.3218 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 3.7220 -3.3218 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.1516 -2.6182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 4.1355 -4.0468 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.6705 -2.6612 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 0.8136 -3.1929 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 6.6141 -4.0468 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 1.0661 0.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3438 -4.7693 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 5.3599 -1.8852 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 6.2623 -1.9443 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.5244 -2.6612 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 0.0000 -1.0177 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0\n 7.5566 -1.2433 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 6.7349 -1.2433 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.9622 -1.9845 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.9863 -0.5425 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0\n 2 1 2 0 0 0 0\n 3 2 1 0 0 0 0\n 4 5 2 0 0 0 0\n 5 1 1 0 0 0 0\n 6 7 2 0 0 0 0\n 7 14 1 0 0 0 0\n 8 13 2 0 0 0 0\n 9 6 1 0 0 0 0\n 10 1 1 0 0 0 0\n 11 3 1 0 0 0 0\n 12 11 1 0 0 0 0\n 13 12 1 0 0 0 0\n 14 12 2 0 0 0 0\n 15 9 1 0 0 0 0\n 16 2 1 0 0 0 0\n 17 9 2 0 0 0 0\n 18 10 2 0 0 0 0\n 19 7 1 0 0 0 0\n 20 8 1 0 0 0 0\n 21 15 2 0 0 0 0\n 22 15 1 0 0 0 0\n 23 10 1 0 0 0 0\n 24 26 1 0 0 0 0\n 25 21 1 0 0 0 0\n 26 22 2 0 0 0 0\n 27 24 1 0 0 0 0\n 4 3 1 0 0 0 0\n 8 6 1 0 0 0 0\n 25 24 2 0 0 0 0\nM END", "smiles": "c1cc(ccc1C(=O)c2c(cc(cc2Cl)Cn3c(c(C(=O)N)nn3)N)Cl)Cl", "formula": "C17H12Cl3N5O2", "atropisomerism": "No", "charge": 0, "count": 1, "stereochemistry": "ACHIRAL", "defined_stereo": 0, "ez_centers": 0, "molecular_weight": "424.6689", "optical_activity": "NONE", "references": [ "df30a1bc-fc12-4726-82c4-560617eaef0c", "f85256d3-3c87-4d6c-beef-cf350d53ef1e" ], "stereo_centers": 0 }, "unii": "6ST3ZF52WB" } ] }