{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "29181eaf-f894-4164-b303-0089e78912db",
          "code": "C65208",
          "type": "PRIMARY",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C65208",
          "code_system": "NCI_THESAURUS",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "a2db7522-00e8-49e3-9564-7ff77bebb054",
          "code": "N0000185371",
          "comments": "Established Pharmacologic Class [EPC]|Non-Standardized Food Allergenic Extract [EPC]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000185371",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "d043ba06-8b44-47ac-9abf-a3036c1e9647",
          "code": "892565",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/892565/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "c9e13691-7e85-4360-b6fd-0ebf4ac2daa2",
          "code": "SUB49712",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "434e22df-4170-43de-9fc6-b12552638cc7",
          "code": "N0000184306",
          "comments": "Cell-mediated Immunity [PE]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000184306",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "ad9b660f-fac6-4c2c-a47e-cf56ab1803cb",
          "code": "N0000175629",
          "comments": "Increased Histamine Release [PE]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000175629",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "c9d9c064-4f94-4e3f-a5e6-af39e8d201db",
          "code": "N0000007512",
          "comments": "Dietary Proteins [Chemical/Ingredient]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000007512",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "82aa302d-0ada-4084-91fc-1bdef63060c3",
          "code": "N0000171131",
          "comments": "Allergens [Chemical/Ingredient]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000171131",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "3ade1688-895a-4058-a5e0-1cbd71c5c4f2",
          "code": "N0000185015",
          "comments": "Fruit Proteins [Chemical/Ingredient]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000185015",
          "code_system": "NDF-RT",
          "references": [
            "3722b12b-6ef0-476f-bd3d-3b4c60626eb2"
          ]
        },
        {
          "uuid": "3fb2f229-0d99-4c6d-90d6-422a63ffbba1",
          "code": "5EVU04N5QU",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "469a869b-7892-ed04-364d-f500370811a9",
          "code": "DB10549",
          "type": "PRIMARY",
          "url": "https://go.drugbank.com/drugs/DB10549",
          "code_system": "DRUG BANK",
          "references": [
            "f1c1c131-82af-089b-8546-ea927a30e900"
          ]
        },
        {
          "uuid": "ba61fff0-87dc-18a9-0d80-fc98cc3a3776",
          "code": "5EVU04N5QU",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=5EVU04N5QU",
          "code_system": "DAILYMED",
          "references": [
            "a102ee88-8fe7-03cf-e645-446f01ea10c5"
          ]
        },
        {
          "uuid": "7f9510ad-b29d-84fc-0741-1a5584a47391",
          "code": "N0000185371",
          "comments": "Established Pharmacologic Class [EPC]|Non-Standardized Food Allergenic Extract [EPC]",
          "type": "PRIMARY",
          "url": "https://nciterms.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=VA_NDFRT&code=N0000185371",
          "code_system": "NDF-RT",
          "references": [
            "a05271bb-0229-d2cc-0ccb-acfc989b7eb2"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "ac9b73c7-9753-4462-801f-326517774376",
          "amount": {
            "uuid": "106d8c9a-85a4-427d-abe3-5a0d4301cf12"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "119f3951-fcd0-4055-af30-23c4b2dfc95f",
            "refuuid": "6621ed44-3f97-4c23-8f68-1ce0203d7cf9",
            "name": "ORANGE",
            "unii": "5EVU04N5QU",
            "linking_id": "5EVU04N5QU",
            "ref_pname": "ORANGE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "1bd2e354-d7c6-4289-a1da-fb9904296b13",
          "amount": {
            "uuid": "a7aa7fe1-3f21-411a-a7a2-436539910fd0"
          },
          "type": "SUB_CONCEPT->SUBSTANCE",
          "related_substance": {
            "uuid": "901d87fa-e4b1-4777-a8ad-bec80d3c864d",
            "refuuid": "1d47e407-7693-4bcf-afd3-b45ffb65ba94",
            "name": "ORANGE FRUIT WATER",
            "linking_id": "1d47e407-7693-4bcf-afd3-b45ffb65ba94",
            "ref_pname": "ORANGE FRUIT WATER",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "6a430f56-8fd8-4ac3-a5be-9cdc895b701c",
          "type": "SUB_CONCEPT->SUBSTANCE",
          "related_substance": {
            "uuid": "05b3e273-41aa-452f-b3de-b9a31bcfac57",
            "refuuid": "56bf3da9-ecee-41aa-8ef4-15ee7c82dcf2",
            "name": "ALLERGENIC EXTRACT- ORANGE CITRUS SINENSIS",
            "linking_id": "56bf3da9-ecee-41aa-8ef4-15ee7c82dcf2",
            "ref_pname": "ALLERGENIC EXTRACT- ORANGE CITRUS SINENSIS",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "structurallyDiverse",
      "names": [
        {
          "uuid": "bedc04c1-8ddb-46d2-8ffe-3b1c0efd665a",
          "name": "B1339 [LANGUAL]",
          "stdName": "B1339 [LANGUAL]",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "34c99ad3-ee9c-48fd-ac45-e458ce5383ac",
            "69444fee-1399-4ee9-9b84-e334dcd0775a"
          ],
          "display_name": false
        },
        {
          "uuid": "4ac8aa7b-05fd-3585-cc2d-4c9a63e10472",
          "name": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT",
          "stdName": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "fd2cab86-bc2a-a32c-85b3-b8a2785ccc42",
            "84798da4-fd13-765a-100c-939e1e8ead54",
            "81a6d467-cec5-03ee-6d73-d0808323a15d"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "cd2efdf2-3d57-8e26-7016-2275517dce69",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "9454e1de-8db0-48e6-8987-17d6026493b2",
          "name": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT POWDER",
          "stdName": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT POWDER",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": true,
          "references": [
            "4b6ca130-741e-473a-a3b5-ee5c631ea3e7",
            "6498896a-27b9-4e78-8623-ca2f40a5628f",
            "a62d94a1-ce6c-44a4-ab4c-d6a41db09680"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "303fbd3b-1644-4844-855f-65a803b02340",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "2ab8850d-a39f-46a8-316f-a1ff25cdf8c6",
          "name": "CITRUS AURANTIUM DULCIS FRUIT EXTRACT",
          "stdName": "CITRUS AURANTIUM DULCIS FRUIT EXTRACT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "81a6d467-cec5-03ee-6d73-d0808323a15d",
            "84798da4-fd13-765a-100c-939e1e8ead54"
          ],
          "display_name": false
        },
        {
          "uuid": "fab0797d-d134-4fe2-aa20-e8a808da8a1e",
          "name": "CITRUS AURANTIUM VAR. SINENSIS FRUIT",
          "stdName": "CITRUS AURANTIUM VAR. SINENSIS FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "28429633-8599-4462-a054-84b84f8cb935"
          ],
          "display_name": false
        },
        {
          "uuid": "763d56a4-6e0d-47a0-8d37-20772084712a",
          "name": "CITRUS SINENSIS FRUIT",
          "stdName": "CITRUS SINENSIS FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "817f3fa2-edbb-4f9f-8d69-8f38c889c03f",
            "28429633-8599-4462-a054-84b84f8cb935",
            "1d361616-b66e-4c7c-850e-bee6a666f67c",
            "7b3df5e6-b2d4-4bed-a76e-8ac18a8b2097"
          ],
          "display_name": false
        },
        {
          "uuid": "e53c8b1d-ee1c-4789-b781-7e944be0bbd3",
          "name": "CITRUS X SINENSIS FRUIT",
          "stdName": "CITRUS X SINENSIS FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4df7feb7-bd1d-4aa1-832f-c85133bad71f",
            "d8941c74-cc5e-43f6-b996-c6002c91d2e8"
          ],
          "display_name": false
        },
        {
          "uuid": "76744a95-d019-4a39-9663-5fd4507258cc",
          "name": "NAVEL ORANGE FRUIT",
          "stdName": "NAVEL ORANGE FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4df7feb7-bd1d-4aa1-832f-c85133bad71f",
            "d8941c74-cc5e-43f6-b996-c6002c91d2e8"
          ],
          "display_name": false
        },
        {
          "uuid": "69bf6099-07c3-463e-853a-fff9a90e75c9",
          "name": "ORANGE",
          "stdName": "ORANGE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "156cd95f-a0ba-4f6e-8d9f-42c29c24a6f6"
          ],
          "display_name": true
        },
        {
          "uuid": "1491fdce-6ef9-b2db-7cc2-ad1a57e7b6db",
          "name": "ORANGE FRUIT EXTRACT",
          "stdName": "ORANGE FRUIT EXTRACT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "81a6d467-cec5-03ee-6d73-d0808323a15d",
            "84798da4-fd13-765a-100c-939e1e8ead54"
          ],
          "display_name": false
        },
        {
          "uuid": "cd6ad4bf-2414-46fe-b3fd-01fd5e7ec2bb",
          "name": "ORANGES, RAW, NAVELS",
          "stdName": "ORANGES, RAW, NAVELS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "613e4dee-e67f-4b3b-afc6-d7847377cff0",
            "5ed8257a-2fab-4516-95ce-fd23d8b9cc55"
          ],
          "display_name": false
        },
        {
          "uuid": "bb681973-1569-44de-a22a-23adb6aab034",
          "name": "SWEET ORANGE FRUIT",
          "stdName": "SWEET ORANGE FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "28429633-8599-4462-a054-84b84f8cb935"
          ],
          "display_name": false
        },
        {
          "uuid": "1be99e4d-7b4e-470a-a9bd-ab6b5a2c0f98",
          "name": "VALENCIA ORANGE FRUIT",
          "stdName": "VALENCIA ORANGE FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "4df7feb7-bd1d-4aa1-832f-c85133bad71f",
            "d8941c74-cc5e-43f6-b996-c6002c91d2e8"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "156cd95f-a0ba-4f6e-8d9f-42c29c24a6f6",
          "citation": "CDER INACTIVE INGREDIENT 9-OCT-2007",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "b19aecb8-9215-4f02-9dda-41a455314664",
          "citation": "2006",
          "doc_type": "FOOD LOVERS COMPANION",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "28429633-8599-4462-a054-84b84f8cb935",
          "citation": "ITIS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4df7feb7-bd1d-4aa1-832f-c85133bad71f",
          "citation": "NCBI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "d8941c74-cc5e-43f6-b996-c6002c91d2e8",
          "citation": "NCBI",
          "doc_type": "NCBI",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "613e4dee-e67f-4b3b-afc6-d7847377cff0",
          "citation": "USDA",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "5ed8257a-2fab-4516-95ce-fd23d8b9cc55",
          "citation": "USDA",
          "doc_type": "USDA",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "34c99ad3-ee9c-48fd-ac45-e458ce5383ac",
          "citation": "LANGUAL",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "69444fee-1399-4ee9-9b84-e334dcd0775a",
          "citation": "LANGUAL",
          "doc_type": "LANGUAL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "817f3fa2-edbb-4f9f-8d69-8f38c889c03f",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "1d361616-b66e-4c7c-850e-bee6a666f67c",
          "citation": "WHO DRUG DICTIONARY",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4b6ca130-741e-473a-a3b5-ee5c631ea3e7",
          "citation": "PCPC-DB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6498896a-27b9-4e78-8623-ca2f40a5628f",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3722b12b-6ef0-476f-bd3d-3b4c60626eb2",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391404000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e900fc07-da7e-4e9d-a8ae-1405468536f3",
          "citation": "SRS import [5EVU04N5QU]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=5EVU04N5QU",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391404000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "2a3c9912-0913-49d7-9215-cc86553f6763",
          "citation": "Catalog of Life 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7b3df5e6-b2d4-4bed-a76e-8ac18a8b2097",
          "citation": "CITRUS SINENSIS FRUIT [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "a62d94a1-ce6c-44a4-ab4c-d6a41db09680",
          "citation": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT POWDER [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "12ffc00a-8f79-480c-2349-88da79c6d0f7",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "f1c1c131-82af-089b-8546-ea927a30e900",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "a102ee88-8fe7-03cf-e645-446f01ea10c5",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "81a6d467-cec5-03ee-6d73-d0808323a15d",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "84798da4-fd13-765a-100c-939e1e8ead54",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "9d7865a7-1eaa-6f94-af12-b7a4915f9412",
          "citation": "INCI",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a05271bb-0229-d2cc-0ccb-acfc989b7eb2",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493391404000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fd2cab86-bc2a-a32c-85b3-b8a2785ccc42",
          "citation": "CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "6621ed44-3f97-4c23-8f68-1ce0203d7cf9",
      "version": "14",
      "structurally_diverse": {
        "uuid": "3bae2d0c-6f33-448d-98df-f489c986280b",
        "parent_substance": {
          "uuid": "a8eb33bc-d6e7-4dda-a9b8-ea1d7e8b5fab",
          "refuuid": "b99d9560-e218-4a59-90df-ee231ec2c84f",
          "name": "Citrus x sinensis whole",
          "unii": "37673443KL",
          "linking_id": "37673443KL",
          "ref_pname": "Citrus x sinensis whole",
          "substance_class": "reference"
        },
        "part": [
          "fruit"
        ],
        "references": [
          "2a3c9912-0913-49d7-9215-cc86553f6763",
          "e900fc07-da7e-4e9d-a8ae-1405468536f3"
        ],
        "source_material_class": "ORGANISM",
        "source_material_type": "PLANT"
      },
      "modifications": {
        "uuid": "6de8133a-d68f-4d38-9364-27535b88a938"
      },
      "unii": "5EVU04N5QU"
    }
  ]
}