{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "cb62cb96-4db5-4061-b788-dd4408e447eb",
          "code": "2,3-HEXANEDIONE",
          "comments": "JECFA|FUNCTIONAL CLASSIFICATION|Flavouring Agent",
          "type": "PRIMARY",
          "url": "http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=3232",
          "code_system": "JECFA EVALUATION",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a"
          ]
        },
        {
          "uuid": "0658368a-d0de-4c49-9e9f-6d63a4b7ab83",
          "code": "3848-24-6",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=3848-24-6",
          "code_system": "CAS",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a",
            "6e7ccfcb-ecc7-4797-81dc-d0c5025cf653"
          ]
        },
        {
          "uuid": "eca4d11c-9025-49f6-9ad7-b26919e7971b",
          "code": "C043231",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67043231",
          "code_system": "MESH",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a"
          ]
        },
        {
          "uuid": "a68afd89-0cfb-4ccd-8180-14304291956e",
          "code": "21 CFR 172.515",
          "comments": "PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION|Subpart F--Flavoring Agents and Related Substances|Sec. 172.515 Synthetic flavoring substances and adjuvants.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=172.515",
          "code_system": "CFR",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a"
          ]
        },
        {
          "uuid": "07acdc32-5002-47f3-81d4-135e553b8be1",
          "code": "223-350-8",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.021.229",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a"
          ]
        },
        {
          "uuid": "88a7ea6a-9b6b-4cd7-9b9a-45474e50ab95",
          "code": "19707",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/19707",
          "code_system": "PUBCHEM",
          "references": [
            "38a62a06-e8be-44a1-9a7a-654b2c8e586a"
          ]
        },
        {
          "uuid": "0805ae17-6614-1b47-b069-c76738819b96",
          "code": "DTXSID2047066",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID2047066",
          "code_system": "EPA CompTox",
          "references": [
            "8c7a379c-46bc-b37b-0725-a1947343aeea"
          ]
        },
        {
          "uuid": "537211c1-aea4-4670-aa80-fd6bea8d38f1",
          "code": "559ANR3NVS",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "a7e64d94-4ec5-a13f-5248-c733c04f6a25",
          "code": "87583",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:87583",
          "code_system": "CHEBI",
          "references": [
            "758b1895-e816-fc0b-a553-b6de78c2d9fe"
          ]
        },
        {
          "uuid": "c8541710-b8a3-548f-b75b-fcc6c8da384f",
          "code": "31665",
          "type": "PRIMARY",
          "url": "https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=31665",
          "code_system": "NSC",
          "references": [
            "406cd2af-dd42-f5d5-d43e-66e01fb0dd73"
          ]
        },
        {
          "uuid": "fc309e09-c138-b3cf-1058-3afdb638a4b1",
          "code": "93",
          "type": "PRIMARY",
          "url": "https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-flav/details/en/c/93/",
          "code_system": "JECFA MONOGRAPH",
          "references": [
            "7f83fc86-2512-3250-0277-e4de5b8af5b7"
          ]
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "c2b7249c-5848-498d-838d-a153472fcb95",
          "name": "2,3-HEXANEDIONE",
          "stdName": "2,3-HEXANEDIONE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86bf7281-0316-42bd-8060-1726c1b1fb5e",
            "8efc1607-731e-4a43-b32d-ec1f723db69e",
            "5e97f027-4901-4f65-aa47-f628d15f3210",
            "426fd504-9be2-400f-8f41-df75c9ee811a"
          ],
          "display_name": true
        },
        {
          "uuid": "2b02007c-512b-48ac-8398-869a9a5991d8",
          "name": "2,3-HEXANEDIONE [FHFI]",
          "stdName": "2,3-HEXANEDIONE [FHFI]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8efc1607-731e-4a43-b32d-ec1f723db69e",
            "86bf7281-0316-42bd-8060-1726c1b1fb5e"
          ],
          "display_name": false
        },
        {
          "uuid": "c9d1b285-279e-4ff4-a4a5-1c853802b549",
          "name": "ACETYL BUTYRYL",
          "stdName": "ACETYL BUTYRYL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86bf7281-0316-42bd-8060-1726c1b1fb5e",
            "113232a0-95e9-4836-bd8b-a73bf3eff0a9"
          ],
          "display_name": false
        },
        {
          "uuid": "813ec28e-24c3-4908-b068-3550f418ad7b",
          "name": "ACETYLBUTYRYL",
          "stdName": "ACETYLBUTYRYL",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86bf7281-0316-42bd-8060-1726c1b1fb5e",
            "5e97f027-4901-4f65-aa47-f628d15f3210"
          ],
          "display_name": false
        },
        {
          "uuid": "76749866-40df-45fa-95af-01692f62a5c8",
          "name": "FEMA NO. 2558",
          "stdName": "FEMA NO. 2558",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "34c2bb37-fe79-4cb5-bd4a-c84b7af15ee0"
          ],
          "display_name": false
        },
        {
          "uuid": "61bf5bac-eff0-481b-b928-aef72bb438a7",
          "name": "HEXANE-2,3-DIONE",
          "stdName": "HEXANE-2,3-DIONE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "8efc1607-731e-4a43-b32d-ec1f723db69e",
            "86bf7281-0316-42bd-8060-1726c1b1fb5e"
          ],
          "display_name": false
        },
        {
          "uuid": "61a3ede1-9be1-46b0-a94b-cd0cfbb295e3",
          "name": "HEXANEDIONE, 2,3-",
          "stdName": "HEXANEDIONE, 2,3-",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "566ed541-23cf-4654-bf84-71324e662756"
          ],
          "display_name": false
        },
        {
          "uuid": "fd8994f6-27a2-4744-968d-9d7565be878a",
          "name": "NSC-31665",
          "stdName": "NSC-31665",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "86bf7281-0316-42bd-8060-1726c1b1fb5e",
            "5e97f027-4901-4f65-aa47-f628d15f3210"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "566ed541-23cf-4654-bf84-71324e662756",
          "citation": "ICSAS BATCH 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "5e97f027-4901-4f65-aa47-f628d15f3210",
          "citation": "STN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "86bf7281-0316-42bd-8060-1726c1b1fb5e",
          "citation": "STN (SCIFINDER)",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "34c2bb37-fe79-4cb5-bd4a-c84b7af15ee0",
          "citation": "CHEMID 2010",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8efc1607-731e-4a43-b32d-ec1f723db69e",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "113232a0-95e9-4836-bd8b-a73bf3eff0a9",
          "citation": "YES",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "38a62a06-e8be-44a1-9a7a-654b2c8e586a",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390957000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "4204ae9a-62de-403d-8a96-304e866572b2",
          "citation": "SRS import [559ANR3NVS]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=559ANR3NVS",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390957000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "426fd504-9be2-400f-8f41-df75c9ee811a",
          "citation": "2,3-HEXANEDIONE [FHFI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "8c7a379c-46bc-b37b-0725-a1947343aeea",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=3848-24-6",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "758b1895-e816-fc0b-a553-b6de78c2d9fe",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "6e7ccfcb-ecc7-4797-81dc-d0c5025cf653",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "406cd2af-dd42-f5d5-d43e-66e01fb0dd73",
          "citation": "NCI",
          "doc_type": "NCI DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "7f83fc86-2512-3250-0277-e4de5b8af5b7",
          "citation": "JECFA",
          "doc_type": "JECFA",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "3d3fc4f2-bb83-4c08-a1be-7e6bcf3a3e1d",
          "id": "3d3fc4f2-bb83-4c08-a1be-7e6bcf3a3e1d",
          "molfile": "\n  Marvin  01132103152D          \n\n  8  7  0  0  0  0            999 V2000\n    8.7050   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.9905   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.2760   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.5615   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.5615   -4.1342    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8470   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.1332   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8470   -6.1967    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  3  2  1  0  0  0  0\n  4  3  1  0  0  0  0\n  4  5  2  0  0  0  0\n  4  6  1  0  0  0  0\n  6  7  1  0  0  0  0\n  6  8  2  0  0  0  0\nM  END",
          "smiles": "CCCC(=O)C(=O)C",
          "formula": "C6H10O2",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "bb6414ee-e0dc-433f-b1c5-1549895e42cc"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "114.1426",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "bc1fece5-9b36-4a29-a8a5-7395d9d3ab3b",
      "version": "6",
      "structure": {
        "id": "96cc471f-be3b-4184-9d39-88f035c33400",
        "molfile": "\n  Marvin  01132107502D          \n\n  8  7  0  0  0  0            999 V2000\n    6.5615   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8470   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.1332   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.8470   -6.1967    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    7.2760   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.9905   -4.9592    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.7050   -5.3717    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.5615   -4.1342    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  2  4  2  0  0  0  0\n  1  5  1  0  0  0  0\n  5  6  1  0  0  0  0\n  6  7  1  0  0  0  0\n  1  8  2  0  0  0  0\nM  END",
        "smiles": "CCCC(=O)C(=O)C",
        "formula": "C6H10O2",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "114.1426",
        "optical_activity": "NONE",
        "references": [
          "34c2bb37-fe79-4cb5-bd4a-c84b7af15ee0",
          "4204ae9a-62de-403d-8a96-304e866572b2"
        ],
        "stereo_centers": 0
      },
      "unii": "559ANR3NVS"
    }
  ]
}