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"90d35a7f-1f6d-4673-9197-b9540d1828a8", "name": "m-AMINOBENZOIC ACID", "unii": "G2X3B3O37U", "linking_id": "G2X3B3O37U", "ref_pname": "m-AMINOBENZOIC ACID" } }, { "uuid": "f11fa66e-4cd3-4eb4-be8a-8dcf021209cb", "amount": { "uuid": "4f857492-cb68-4f0a-8fe2-3e83335ac75b", "units": "PERCENT PEAK AREA", "high_limit": 0.1 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 0.6", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "f1c8fc46-97ff-4766-8882-e5295bfb05b7" ], "related_substance": { "uuid": "21cf7e3b-5f92-40db-909f-3163213613bf", "refuuid": "6a86d4dd-cd18-4e3f-8aef-a7a31922211c", "name": "5-AMINO-2-HYDROXY-3-(4-SULFOPHENYL)BENZOIC ACID", "unii": "OVF1UF1IB2", "linking_id": "OVF1UF1IB2", "ref_pname": "5-AMINO-2-HYDROXY-3-(4-SULFOPHENYL)BENZOIC ACID" } }, { "uuid": "cbee0790-8804-4372-ad65-a678bb123129", "amount": { "uuid": "38908d65-bc69-4807-8de2-64170ebefa10", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 4.5", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "be077a74-811a-4156-b7e9-b27286d41b9b" ], "related_substance": { "uuid": "db29f8c5-b1e3-49ae-87e1-9ce66e1ecb24", "refuuid": "0c558fc3-f708-4710-8ca6-b30450eed449", "name": "O-Chlorobenzoic acid", "unii": "8P0867193V", "linking_id": "8P0867193V", "ref_pname": "O-Chlorobenzoic acid" } }, { "uuid": "33372f09-dc6a-424b-9aa7-f295ab7ff18e", "amount": { "uuid": "5e019cb8-007f-4985-a2ca-7c511a0c1ccb", "units": "PERCENT PEAK AREA", "high_limit": 0.1 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 0.6", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "692dc0ce-bc99-4213-bb5b-86d9e12130cd" ], "related_substance": { "uuid": "e004815d-394b-42bb-af17-c4264cd5f878", "refuuid": "66e5e115-6422-4ee4-980e-7c762675685b", "name": "SULFANILIC ACID", "unii": "434Z8C2635", "linking_id": "434Z8C2635", "ref_pname": "SULFANILIC ACID" } }, { "uuid": "15b57a71-11c7-4fc3-ab96-eed0705a5f8c", "amount": { "uuid": "e7cdbe7f-36ed-4f91-9b5e-ea2c6e908c46", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "3527e132-0ca2-4072-ac9e-5d92c8c921a0" ], "related_substance": { "uuid": "d3d16893-5b84-48b8-b13f-039fefabda6d", "refuuid": "6b8afdff-ca4f-46cf-a729-3174a1d2533b", "name": "2-CHLORO-3-NITROBENZOIC ACID", "unii": "KG8W66PX35", "linking_id": "KG8W66PX35", "ref_pname": "2-CHLORO-3-NITROBENZOIC ACID" } }, { "uuid": "8c5ab6fe-d907-46da-bac9-93d3ec3f8a02", "amount": { "uuid": "3a04b71f-2e32-40c0-a113-0c9bbd0c8955", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "125ededb-440b-43cc-9d6e-6320d1a4204c" ], "related_substance": { "uuid": "594767fc-1aa3-4090-9334-6b74c6667d7b", "refuuid": "f3e84efa-e38a-4f26-b614-b584413a1ce5", "name": "M-AMINOPHENOL", "unii": "L3WTS6QT82", "linking_id": "L3WTS6QT82", "ref_pname": "M-AMINOPHENOL" } }, { "uuid": "f0133292-2560-46ef-885d-e21c98fb8a9a", "amount": { "uuid": "3d483f85-05d0-4ff9-bcd7-92812e0b1ec0", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 1.4", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "05d666b0-e72b-4086-b44a-077a0bb391b8" ], "related_substance": { "uuid": "1e2c9265-4a33-44de-9421-b8d78b74225a", "refuuid": "b0201685-7e19-4c8a-a3cf-3e04505e02e5", "name": "GENTISIC ACID", "unii": "VP36V95O3T", "linking_id": "VP36V95O3T", "ref_pname": "GENTISIC ACID" } }, { "uuid": "7bf2a494-ca6c-4388-9509-e78c34823b1d", "amount": { "uuid": "06f029b5-28f6-4e23-b72b-98e2cbfc7367", "units": "PERCENT PEAK AREA", "high_limit": 0.1 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 2.0", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "9a825db0-7de6-4e06-850e-806a4ae759b6" ], "related_substance": { "uuid": "49ab2788-7e7b-4a68-bbec-93d1dfac206c", "refuuid": "335e7d7f-dc69-47f5-b498-ba4ee22e4ae0", "name": "3,5-DIAMINO-2-HYDROXYBENZOIC ACID", "unii": "J0W94NS4S3", "linking_id": "J0W94NS4S3", "ref_pname": "3,5-DIAMINO-2-HYDROXYBENZOIC ACID" } }, { "uuid": "a85b7517-7071-422a-8bbf-d6d5842173d2", "amount": { "uuid": "cda1da1c-82ec-482a-b515-d37a6d4174cc", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 1.3", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "a4917917-3028-4cb5-8b55-4c57432bdb63" ], "related_substance": { "uuid": "b3d164b4-7ad9-4cc8-8018-60e65228d038", "refuuid": "f74aa595-2207-47ac-b6f3-81b33638e9a2", "name": "Aminosalicylic acid", "unii": "5B2658E0N2", "linking_id": "5B2658E0N2", "ref_pname": "Aminosalicylic acid" } }, { "uuid": "7a50dda9-9265-4a2d-ba8c-1af110ce0deb", "amount": { "uuid": "39757cfc-d606-43c6-b1c3-a94b3aff19d0", "units": "PERCENT PEAK AREA", "high_limit": 0.02 }, "qualification": "USP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (GC)", "references": [ "df12749b-bcc9-41c2-91f7-38af64eff31b" ], "related_substance": { "uuid": "9bf8d964-c941-45b3-adf1-eb0176b03299", "refuuid": "5c4d1dd0-a474-46c9-9416-3170dbee72cd", "name": "p-Aminophenol", "unii": "R7P8FRP05V", "linking_id": "R7P8FRP05V", "ref_pname": "p-Aminophenol" } }, { "uuid": "c5da2b84-5389-4806-a9d9-7565a5a53286", "amount": { "uuid": "9e98a409-a9f1-456a-8904-dda4c6b739f9", "units": "PERCENT PEAK AREA", "high_limit": 0.2 }, "qualification": "USP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "abd49b13-ca6f-46a8-bcb9-69baaa0394a4" ], "related_substance": { "uuid": "6c54b866-af02-4e9d-9626-6eb00771b0e4", "refuuid": "33125bbe-a8c9-49d3-86b0-ef706f2f40a1", "name": "3-AMINOSALICYLIC ACID", "unii": "WN7T1GM9RM", "linking_id": "WN7T1GM9RM", "ref_pname": "3-AMINOSALICYLIC ACID" } }, { "uuid": "dad4f009-d357-488a-8aad-1d5bb903bbbf", "amount": { "uuid": "a8a8add4-d9cd-4a39-9d1d-4cca33dbf4ab", "units": "PPM", "high_limit": 10 }, "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "5e82a5d7-39cd-44d5-be13-3fc9223ec3fe" ], "related_substance": { "uuid": "17518488-8c83-4624-b9df-8df739d1691d", "refuuid": "9b350a80-7a3b-4d7a-8f0c-dacd25d377b4", "name": "Aniline", "unii": "SIR7XX2F1K", "linking_id": "SIR7XX2F1K", "ref_pname": "Aniline" } }, { "uuid": "59828449-c407-4e80-a957-acc8356670c3", "amount": { "uuid": "42dcce03-f0f9-49a8-a112-7a489051dc72", "units": "PERCENT PEAK AREA", "high_limit": 0.02 }, "qualification": "USP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (GC)", "references": [ "c708d608-8505-4501-b8cc-14df327ee235" ], "related_substance": { "uuid": "d013a465-76aa-4da6-a409-5b6b2494dd73", "refuuid": "1f20a186-c8c5-4b00-a513-6ec9152b7325", "name": "2-Aminophenol", "unii": "23RH73DZ65", "linking_id": "23RH73DZ65", "ref_pname": "2-Aminophenol" } }, { "uuid": "a5d620c7-42c7-47b3-a3a7-a10d07e20502", "amount": { "uuid": "bc6657cb-68bc-4669-8efb-cfb8ce88ed45", "units": "PERCENT PEAK AREA", "high_limit": 0.3 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 1.4", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "7525957e-2306-41d1-a893-d6a3baf9987b" ], "related_substance": { "uuid": "f505c121-00f9-42ac-be59-bd8f2e3fc344", "refuuid": "77ecc185-155e-4f2d-8b74-81c91be840d2", "name": "Salicylic acid", "unii": "O414PZ4LPZ", "linking_id": "O414PZ4LPZ", "ref_pname": "Salicylic acid" } }, { "uuid": "ee1984a2-3b06-4d99-8e60-0195a45f5120", "amount": { "uuid": "8f3cf5df-49d6-4db7-9448-eb583bf1b672", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "ab7edc6d-25a5-4b47-af7d-3cc144de3f47" ], "related_substance": { "uuid": "ab5df1ef-bac7-4d96-ac06-2fc20ebbb744", "refuuid": "8d01d9b4-f8dd-4aea-a1bd-5003a6f4ffc9", "name": "PHENYLAZOSALICYLIC ACID", "unii": "0JGZ1HX6EX", "linking_id": "0JGZ1HX6EX", "ref_pname": "PHENYLAZOSALICYLIC ACID" } }, { "uuid": "bb540918-f35b-4dcd-805c-12598e0928b3", "amount": { "uuid": "bddf44e1-f54b-45d8-89da-bebb3dda5d72", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 1.7", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "373fb9d5-1c58-47e5-bd54-5d976b5e9478" ], "related_substance": { "uuid": "5ad745b2-f4cd-4b97-b8b1-b7b75346bb0f", "refuuid": "400478df-c1de-4ada-a7d7-fac9ee794fdf", "name": "2-Chloro-5-nitrobenzoic acid", "unii": "P27EEY2MW8", "linking_id": "P27EEY2MW8", "ref_pname": "2-Chloro-5-nitrobenzoic acid" } }, { "uuid": "05165098-5832-4362-b9d9-ebbe93e1abd8", "amount": { "uuid": "a5cc3bf4-0235-4035-88aa-66f8b4fea420", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "774ea65c-c7fd-41df-9322-f9495358d982" ], "related_substance": { "uuid": "190318af-c1f2-4828-9bf7-61b6abe7991f", "refuuid": "cfdd5d4e-1438-4515-b168-f3ebd8e16170", "name": "5-NITROSALICYLIC ACID", "unii": "82L9G7FYZ3", "linking_id": "82L9G7FYZ3", "ref_pname": "5-NITROSALICYLIC ACID" } }, { "uuid": "64eb74f7-bd88-4ef0-bfd2-f33de90a1487", "amount": { "uuid": "7bf600d2-c330-4d01-93a5-7adcfd1de5fd", "units": "PERCENT PEAK AREA", "high_limit": 0.05 }, "comments": "Correction factors: for the calculation of contents, multiply the peak areas by 1.3", "qualification": "EP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (HPLC/UV)", "references": [ "c4e83edb-2ddb-4f16-bde3-505d2ba1b305" ], "related_substance": { "uuid": "bc0a9b8f-a1ee-430b-999c-4751b66d778c", "refuuid": "da883549-a657-4011-bca0-a7db8ff1ff05", "name": "3-NITROSALICYLIC ACID", "unii": "47661X4L2C", "linking_id": "47661X4L2C", "ref_pname": "3-NITROSALICYLIC ACID" } }, { "uuid": "a31db04a-1e0a-4365-8acc-66cfbbcaf76d", "amount": { "uuid": "ab7dfb14-91dc-47ef-ba5b-34c4165a8c95", "units": "PPM", "high_limit": 5 }, "qualification": "USP", "type": "IMPURITY->PARENT", "interaction_type": "CHROMATOGRAPHIC PURITY (GC)", "references": [ "8ca6c1b8-11fa-4f81-91b1-b4fad438a57c" ], "related_substance": { "uuid": "fb7f4b24-3982-4cfd-bec1-cbcdefe53ce9", "refuuid": "9b350a80-7a3b-4d7a-8f0c-dacd25d377b4", "name": "Aniline", "unii": "SIR7XX2F1K", "linking_id": "SIR7XX2F1K", "ref_pname": "Aniline", "substance_class": "reference" } }, { "uuid": "d686ba59-984d-40e9-8141-f73c6b05c573", "amount": { "uuid": "02abda03-cc00-46d0-a063-efb79fcbaaf9" }, "type": "IMPURITY->PARENT", "references": [ "5a6d596a-0141-4163-b20d-e63c6274666c" ], "related_substance": { "uuid": "12d7f1ae-43bc-4bff-9c64-4b1ce5bdfaf0", "refuuid": "ca3552d2-3991-4089-b8c6-06ce9bcec771", "name": "5-(2-FORMYL-5-(HYDROXYMETHYL)-1H-PYRROL-1-YL)-2-HYDROXYBENZOIC ACID", "unii": "84588S33E9", "linking_id": "84588S33E9", "ref_pname": "5-(2-FORMYL-5-(HYDROXYMETHYL)-1H-PYRROL-1-YL)-2-HYDROXYBENZOIC ACID" } }, { "uuid": "3028ca59-8076-46a8-83c7-b84e462a7ecb", "amount": { 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