{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "b3e0332a-9fb7-40cd-93f2-2652c8e89d67",
          "code": "SUB33546",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "71c41fbb-4e61-4b38-b72c-a467debaba5a"
          ]
        },
        {
          "uuid": "4a988b86-bdff-2e0b-31e2-598d4ce5168b",
          "code": "502 (Number of products:199)",
          "comments": "Dietary Supplement Label Database|Botanical|Indian Long Pepper",
          "type": "PRIMARY",
          "url": "https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=502&item=Indian Long Pepper",
          "code_system": "DSLD",
          "references": [
            "44775a9b-5b93-fb6d-3886-758e6d5f8292"
          ]
        },
        {
          "uuid": "9a623c6c-3ef7-4d2c-889b-fca1a02bb93f",
          "code": "2NMG4EA7B1",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "81725d9f-1a67-90de-c9c4-a9a8227ee423",
          "code": "2NMG4EA7B1",
          "type": "PRIMARY",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=2NMG4EA7B1",
          "code_system": "DAILYMED",
          "references": [
            "6f86bb48-eae7-c5c5-2ec0-8ae87f298df3"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "c6a099c4-e6cb-4140-9cef-7213d10d3da2",
          "type": "CONSTITUENT ALWAYS PRESENT->PARENT",
          "references": [
            "89a46f07-075f-428f-adaf-4a039949a012"
          ],
          "related_substance": {
            "uuid": "68fee3cf-eea7-4977-8b62-c2a4d65a1c1d",
            "refuuid": "11cb5a7e-3e7a-423c-aeb0-6727f113dbd2",
            "name": "PIPERLONGUMINE",
            "unii": "SGD66V4SVJ",
            "linking_id": "SGD66V4SVJ",
            "ref_pname": "PIPERLONGUMINE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "9ad350d0-6a9b-4c94-9d47-375ecebd832e",
          "type": "SUB_CONCEPT->SUBSTANCE",
          "related_substance": {
            "uuid": "92f55992-e337-4005-a590-22ab9fa95e0d",
            "refuuid": "18304853-c393-4f6f-9a69-25d1e089f577",
            "name": "PIPER LONGUM FRUIT EXTRACT",
            "linking_id": "18304853-c393-4f6f-9a69-25d1e089f577",
            "ref_pname": "PIPER LONGUM FRUIT EXTRACT",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "c8b7287b-adc4-4968-adfe-34be2889a5f7",
          "amount": {
            "uuid": "bf15e7ba-bcf7-4627-b6e5-20371cb4a55e"
          },
          "comments": "novel nanomolar inhibitor of endocannabinoid uptake IC50 = 288 nM in U937 cells.",
          "type": "ACTIVE CONSTITUENT ALWAYS PRESENT->PARENT",
          "references": [
            "71df3480-d526-4f70-9d75-b8a1c1b8a340"
          ],
          "related_substance": {
            "uuid": "51d3ee9f-81e5-489e-a1ef-6f658c6e93af",
            "refuuid": "28134964-a1d5-4344-b70a-c8d6a8f8d727",
            "name": "GUINEESINE",
            "unii": "7DK8DMU9JX",
            "linking_id": "7DK8DMU9JX",
            "ref_pname": "GUINEESINE"
          }
        }
      ],
      "substance_class": "structurallyDiverse",
      "names": [
        {
          "uuid": "19c8b6f1-69ab-4107-b279-28431b41d0ca",
          "name": "B2956 [LANGUAL]",
          "stdName": "B2956 [LANGUAL]",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0e73eaf1-bb21-438a-8c87-d60b1fc01e72",
            "6825b221-e4d8-4a92-b26e-056e5a212fef"
          ],
          "display_name": false
        },
        {
          "uuid": "2dc41635-51e5-4598-aab6-7bcefea8ff12",
          "name": "BI BA",
          "stdName": "BI BA",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "443430ba-fa7a-41d6-a439-cad0cb1ee59f",
            "fb61f6b8-cffd-45c5-9592-6dc935a51580"
          ],
          "display_name": false
        },
        {
          "uuid": "2620cf16-1f89-4d5a-9d2b-f63b53f00619",
          "name": "BI BO",
          "stdName": "BI BO",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "add5d550-6817-4df2-af4c-08a803f46891",
            "8f89c925-47eb-4d76-9247-501b861f0cba"
          ],
          "display_name": false
        },
        {
          "uuid": "9aae0ffe-b4eb-4150-a442-6932696abed1",
          "name": "BIBO",
          "stdName": "BIBO",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0887b872-ff45-47af-8638-012afad2206c"
          ],
          "display_name": false
        },
        {
          "uuid": "5ea7489d-b581-4760-a069-e497af3e3b86",
          "name": "FEMA NO. 4266",
          "stdName": "FEMA NO. 4266",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "b8b0c952-61fa-4995-87cb-f78d34ad9925",
            "ce28e8e4-20c3-4904-a01a-978fa57fa54b"
          ],
          "display_name": false
        },
        {
          "uuid": "39a57b38-49f7-4a4a-9b0f-24b41f27981a",
          "name": "INDIAN LONG PEPPER",
          "stdName": "INDIAN LONG PEPPER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "18d86c56-e20c-4dc9-bf90-591d62a3fa6e"
          ],
          "display_name": false
        },
        {
          "uuid": "273ab1ae-0d53-40ec-b1d9-3732ceadfad9",
          "name": "JABORANDI PEPPER",
          "stdName": "JABORANDI PEPPER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "add5d550-6817-4df2-af4c-08a803f46891",
            "3a6fbd3b-cf3b-4d92-9583-a5fc0912c089"
          ],
          "display_name": false
        },
        {
          "uuid": "16fcf635-1e42-4c26-920f-af04ff161078",
          "name": "LONG PEPPER",
          "stdName": "LONG PEPPER",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "add5d550-6817-4df2-af4c-08a803f46891",
            "da3ca9ae-5419-4917-a811-00b027e47aed"
          ],
          "display_name": true
        },
        {
          "uuid": "f31b0ad6-ea72-4480-9b62-c27d4101addd",
          "name": "LONG PEPPER FRUIT",
          "stdName": "LONG PEPPER FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "443430ba-fa7a-41d6-a439-cad0cb1ee59f",
            "fb61f6b8-cffd-45c5-9592-6dc935a51580"
          ],
          "display_name": false
        },
        {
          "uuid": "171304e2-7d50-4587-9c0a-9383dfc7e29f",
          "name": "PIPER LONGUM FRUIT",
          "stdName": "PIPER LONGUM FRUIT",
          "type": "of",
          "languages": [
            "en"
          ],
          "preferred": true,
          "references": [
            "87899fe5-e571-4583-8181-415043a12f75",
            "18d86c56-e20c-4dc9-bf90-591d62a3fa6e",
            "12789e60-7a87-43bb-a1f7-74ad2f6fd035",
            "83911e19-e1b2-49a8-935f-a28519cdb56a",
            "e9effd42-8dab-4ad4-b4ed-876fcedd6547",
            "3f794f38-1fae-4f5f-b51a-6e67404339f3",
            "b150ad79-b5b3-44ba-8e63-7bf8acd0e357"
          ],
          "display_name": false,
          "domains": [
            "cosmetic"
          ],
          "name_orgs": [
            {
              "uuid": "321d0a6d-b4c4-473e-a334-cdc9743be6f8",
              "name_org": "INCI"
            }
          ]
        },
        {
          "uuid": "f4ad622e-5087-409c-a819-d57d31952957",
          "name": "PIPERIS LONGI FRUCTUS",
          "stdName": "PIPERIS LONGI FRUCTUS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "443430ba-fa7a-41d6-a439-cad0cb1ee59f",
            "fb61f6b8-cffd-45c5-9592-6dc935a51580"
          ],
          "display_name": false
        },
        {
          "uuid": "33b7a136-0219-4bdc-931a-9d7e14bb874c",
          "name": "PIPERIS LONGUI FRUCTUS",
          "stdName": "PIPERIS LONGUI FRUCTUS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0887b872-ff45-47af-8638-012afad2206c",
            "426b54de-b9aa-45db-9577-8c932f6c0c3c",
            "0f666831-6d14-4196-9c1c-cbcb3dff555b"
          ],
          "display_name": false
        },
        {
          "uuid": "28469df7-d452-4861-947f-52ba56d494b6",
          "name": "PIPERIS LONGUI FRUCTUS [CHP]",
          "stdName": "PIPERIS LONGUI FRUCTUS [CHP]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "426b54de-b9aa-45db-9577-8c932f6c0c3c"
          ],
          "display_name": false
        },
        {
          "uuid": "71ce46c0-0a0c-4b98-9c13-e949d638086b",
          "name": "PIPPALI FRUIT",
          "stdName": "PIPPALI FRUIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "add5d550-6817-4df2-af4c-08a803f46891",
            "00445d0d-a258-4a59-a8ad-e69ebdd7eb58"
          ],
          "display_name": false
        },
        {
          "uuid": "34849c27-0436-217c-d9d7-1f7cc686fb9c",
          "name": "Piper longum fruit [WHO-DD]",
          "stdName": "PIPER LONGUM FRUIT [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "342160c6-e132-5930-cf67-b044059abe5f"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "add5d550-6817-4df2-af4c-08a803f46891",
          "citation": "HOC 2",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "da3ca9ae-5419-4917-a811-00b027e47aed",
          "citation": "SCN",
          "doc_type": "HERBS OF COMMERCE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "18d86c56-e20c-4dc9-bf90-591d62a3fa6e",
          "citation": "ITIS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "00445d0d-a258-4a59-a8ad-e69ebdd7eb58",
          "citation": "AN",
          "doc_type": "HERBS OF COMMERCE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "8f89c925-47eb-4d76-9247-501b861f0cba",
          "citation": "PN",
          "doc_type": "HERBS OF COMMERCE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3a6fbd3b-cf3b-4d92-9583-a5fc0912c089",
          "citation": "OCN",
          "doc_type": "HERBS OF COMMERCE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b8b0c952-61fa-4995-87cb-f78d34ad9925",
          "citation": "FHFI",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "ce28e8e4-20c3-4904-a01a-978fa57fa54b",
          "citation": "HANDBOOK OF FLAVOR INGREDIENTS",
          "doc_type": "HANDBOOK OF FLAVOR INGREDIENTS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "443430ba-fa7a-41d6-a439-cad0cb1ee59f",
          "citation": "MMCM",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fb61f6b8-cffd-45c5-9592-6dc935a51580",
          "citation": "MATERIA MEDICA FOR CHINESE MEDICINE",
          "doc_type": "MATERIA MEDICA FOR CHINESE MEDICINE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "3f794f38-1fae-4f5f-b51a-6e67404339f3",
          "citation": "PCPC",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b150ad79-b5b3-44ba-8e63-7bf8acd0e357",
          "citation": "PERSONAL CARE PRODUCTS COUNCIL",
          "doc_type": "PERSONAL CARE PRODUCTS COUNCIL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "0e73eaf1-bb21-438a-8c87-d60b1fc01e72",
          "citation": "LANGUAL",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6825b221-e4d8-4a92-b26e-056e5a212fef",
          "citation": "LANGUAL",
          "doc_type": "LANGUAL",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "12789e60-7a87-43bb-a1f7-74ad2f6fd035",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "87899fe5-e571-4583-8181-415043a12f75",
          "citation": "WHO DRUG DICTIONARY",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "0887b872-ff45-47af-8638-012afad2206c",
          "citation": "CP",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "426b54de-b9aa-45db-9577-8c932f6c0c3c",
          "citation": "CHP",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "71c41fbb-4e61-4b38-b72c-a467debaba5a",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390864000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "89a46f07-075f-428f-adaf-4a039949a012",
          "citation": "C&E NEWS JULY 27, 2011 P27",
          "doc_type": "JOURNAL ARTICLE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "782c6806-8cb8-4207-8046-5ac0550ea08b",
          "citation": "SRS import [2NMG4EA7B1]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=2NMG4EA7B1",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390864000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "6bf5c54c-85a6-49dd-b8f2-693a5a8d0329",
          "citation": "Catalog of Life 2009",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e9effd42-8dab-4ad4-b4ed-876fcedd6547",
          "citation": "PIPER LONGUM FRUIT [INCI]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "83911e19-e1b2-49a8-935f-a28519cdb56a",
          "citation": "PIPER LONGUM FRUIT [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "0f666831-6d14-4196-9c1c-cbcb3dff555b",
          "citation": "PIPERIS LONGUI FRUCTUS [CHP]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "71df3480-d526-4f70-9d75-b8a1c1b8a340",
          "citation": "Gani, Hakim Md Osman, Md Obydul Hoq, and Tahmina Tamanna. \"Ethnomedicinal, phytochemical and pharmacological properties of Piper longum (Linn).\" Asian Journal of Medical and Biological Research 5.1 (2019): 1-7.",
          "url": "https://www.sciencedirect.com/science/article/pii/S0254629916340637f",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "4ff55555-b6ee-48d0-b5e6-2527dc7e0216",
          "citation": "Gani, Hakim Md Osman, Md Obydul Hoq, and Tahmina Tamanna. \"Ethnomedicinal, phytochemical and pharmacological properties of Piper longum (Linn).\" Asian Journal of Medical and Biological Research 5.1 (2019): 1-7.",
          "url": "https://www.sciencedirect.com/science/article/pii/S0254629916340637f",
          "doc_type": "JA",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "44775a9b-5b93-fb6d-3886-758e6d5f8292",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "6f86bb48-eae7-c5c5-2ec0-8ae87f298df3",
          "citation": "DailyMed",
          "doc_type": "DAILYMED",
          "public_domain": true
        },
        {
          "uuid": "342160c6-e132-5930-cf67-b044059abe5f",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "ac136f36-99c5-4f16-baaa-4c969326aa50",
      "version": "8",
      "structurally_diverse": {
        "uuid": "e98728d9-6d29-435f-8cc7-f9f0d73b9db3",
        "parent_substance": {
          "uuid": "06320788-dd8c-4e8f-b06d-d02e27cd40cb",
          "refuuid": "2d42e631-196f-40fe-9e13-08a30b029bd6",
          "name": "PIPER LONGUM WHOLE",
          "unii": "6I24R87022",
          "linking_id": "6I24R87022",
          "ref_pname": "PIPER LONGUM WHOLE",
          "substance_class": "reference"
        },
        "part": [
          "fruit"
        ],
        "references": [
          "6bf5c54c-85a6-49dd-b8f2-693a5a8d0329",
          "782c6806-8cb8-4207-8046-5ac0550ea08b"
        ],
        "source_material_class": "ORGANISM",
        "source_material_type": "PLANT"
      },
      "modifications": {
        "uuid": "b994e1e2-5786-4e53-a074-aedc336f9bbe"
      },
      "unii": "2NMG4EA7B1"
    }
  ]
}