{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-09-09",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "5e4cf629-2e3a-4b77-bcc6-eb795cf67d58",
          "code": "21 CFR 640.10",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.10 Red Blood Cells.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.10",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "4c6c3188-e1f0-4c4b-bfb4-d5aeba26c038",
          "code": "21 CFR 640.11",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.11 General requirements.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.11",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "ae3746e1-ac72-45dc-9bbc-6e8a70d4757d",
          "code": "21 CFR 640.12",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.12 Suitability of donor.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.12",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "d5af19e1-26dd-4d4e-b938-1c93a09ea60a",
          "code": "21 CFR 640.13",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.13 Collection of the blood.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.13",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "96035109-4041-405f-8de7-0c8fba96b361",
          "code": "21 CFR 640.14",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.14 Testing the blood.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.14",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "dceeaab6-ef20-442f-b0e8-9e738d6ee02b",
          "code": "21 CFR 640.15",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.15 Segments for testing.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.15",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "2b91c6d1-3940-4cc7-a32b-e67ae3a164a1",
          "code": "21 CFR 640.16",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.16 Processing.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.16",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "444c6399-a6c7-477e-b2a9-8b435befb515",
          "code": "21 CFR 640.17",
          "comments": "PART 640 -- ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS|Subpart B--Red Blood Cells|Sec. 640.17 Modifications for specific products.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=640.17",
          "code_system": "CFR",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "a053d41c-c869-4662-b5b7-0e8c4defbc9d",
          "code": "SUB15114MIG",
          "type": "PRIMARY",
          "code_system": "EVMPD",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "aff44099-3d05-495b-aa5b-596532d86d15",
          "code": "CHEMBL2108195",
          "type": "PRIMARY",
          "url": "https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL2108195",
          "code_system": "ChEMBL",
          "references": [
            "627e0509-e2ea-43d7-944b-be12fbd3a161"
          ]
        },
        {
          "uuid": "8f461c99-7930-8452-fe3c-81f08262f204",
          "code": "370712",
          "comments": "ORPHAN DRUG|Designated|Treatment of pancreatic cancer.",
          "type": "PRIMARY",
          "url": "https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=370712",
          "code_system": "FDA ORPHAN DRUG"
        },
        {
          "uuid": "bb7897a2-bf82-cf94-a6e9-15567252fc91",
          "code": "B05AX01",
          "comments": "ATC|BLOOD AND BLOOD FORMING ORGANS|BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS|BLOOD AND RELATED PRODUCTS|Other blood products|erythrocytes",
          "type": "PRIMARY",
          "url": "http://www.whocc.no/atc_ddd_index/?code=B05AX01&showdescription=yes",
          "code_system": "WHO-ATC"
        },
        {
          "uuid": "b820220d-1258-481e-8252-013571699758",
          "code": "2K524Y8G0J",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "3c03e523-c2f1-4000-dd63-4471ba6b9fe3",
          "code": "100000089120",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "051cd781-dea4-8a5c-31a2-bf589659e62e"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "a3835112-ea4a-4382-b0e9-bb3b5d30f4db",
          "amount": {
            "uuid": "7e1be945-4e1a-4113-8beb-fde82db496e8",
            "average": 96,
            "units": "%"
          },
          "comments": "Distributed preferentially into the red cell fraction inblood with most extensive distribution into human red cells",
          "type": "LIGAND->BINDER",
          "references": [
            "fd8ec82f-5a32-4bde-bd9f-885adefe6155"
          ],
          "related_substance": {
            "uuid": "eb911ce7-8a18-4aa4-a552-bfe0fdb7cfd1",
            "refuuid": "272b4724-6f71-4a85-ba64-ba114dec1658",
            "name": "UK-224671",
            "unii": "V7M68E8XRC",
            "linking_id": "V7M68E8XRC",
            "ref_pname": "UK-224671",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "structurallyDiverse",
      "names": [
        {
          "uuid": "54bd55f1-0e07-40b8-84bf-0fb9f4d8497b",
          "name": "BLOOD CELLS, RED",
          "stdName": "BLOOD CELLS, RED",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "99121e11-6942-4a34-a15c-a3dc401eaa3a",
            "47354025-f02c-43f9-9ec8-ea64f35baa95",
            "b26e1834-f4fc-42fb-9dcc-4d57d4ef426d"
          ],
          "display_name": true
        },
        {
          "uuid": "cbf10ef1-5eb1-07da-67f5-f4b1c801274e",
          "name": "BLOOD CELLS, RED [USP IMPURITY]",
          "stdName": "BLOOD CELLS, RED [USP IMPURITY]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "b26e1834-f4fc-42fb-9dcc-4d57d4ef426d"
          ],
          "display_name": false
        },
        {
          "uuid": "1a9d030e-44c5-44d1-a0e6-3965b46c50f4",
          "name": "HUMAN RED BLOOD CELLS",
          "stdName": "HUMAN RED BLOOD CELLS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "cad9ee6b-b777-4115-8c3b-7ff025f14073",
            "c2732982-9289-430f-8f6e-e16aa75df1fa",
            "49076723-7acc-4c6e-807f-2ebc740d31c2",
            "39ebe617-9ac2-41aa-817d-e5419674021d"
          ],
          "display_name": false
        },
        {
          "uuid": "c1888bf9-d3c1-47ec-a1af-e1e68cc29132",
          "name": "Hematocrit",
          "stdName": "HEMATOCRIT",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a4fbec0c-b5d7-470d-8b2e-544a299520f6"
          ],
          "display_name": false
        },
        {
          "uuid": "0d875148-8aeb-46c5-98b7-f1e430759088",
          "name": "RED BLOOD CELLS",
          "stdName": "RED BLOOD CELLS",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7ca4cd0e-02e6-4044-8e44-c01617c89d18",
            "faa2a5ab-2f3b-4ae1-865b-7265b2ad87f2",
            "cad9ee6b-b777-4115-8c3b-7ff025f14073",
            "f83e4d69-62e2-493c-9a11-5d3083ae20e2",
            "c2732982-9289-430f-8f6e-e16aa75df1fa",
            "49076723-7acc-4c6e-807f-2ebc740d31c2",
            "7f9a033a-ab8f-4428-b61e-826ecbbe7bcf"
          ],
          "display_name": false
        },
        {
          "uuid": "439dd085-b2df-40dd-8694-c396f868537a",
          "name": "RED BLOOD CELLS [MART.]",
          "stdName": "RED BLOOD CELLS [MART.]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "7ca4cd0e-02e6-4044-8e44-c01617c89d18",
            "f83e4d69-62e2-493c-9a11-5d3083ae20e2"
          ],
          "display_name": false
        },
        {
          "uuid": "8443bc2a-1ff6-cdb6-7c7d-710e177acaa8",
          "name": "Red blood cells [WHO-DD]",
          "stdName": "RED BLOOD CELLS [WHO-DD]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "880cad81-05ee-16c3-2bce-85639208f5de"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "cad9ee6b-b777-4115-8c3b-7ff025f14073",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "47354025-f02c-43f9-9ec8-ea64f35baa95",
          "citation": "USAN",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "b26e1834-f4fc-42fb-9dcc-4d57d4ef426d",
          "citation": "USP 33",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7ca4cd0e-02e6-4044-8e44-c01617c89d18",
          "citation": "MARTINDALE 2011",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "f83e4d69-62e2-493c-9a11-5d3083ae20e2",
          "citation": "MARTINDALE 2011",
          "doc_type": "MARTINDALE",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "c2732982-9289-430f-8f6e-e16aa75df1fa",
          "citation": "WHO-DD",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "49076723-7acc-4c6e-807f-2ebc740d31c2",
          "citation": "WHO DRUG DICTIONARY",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "627e0509-e2ea-43d7-944b-be12fbd3a161",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390894000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "aff83fb4-120a-4d0c-a447-0fed38ea523f",
          "citation": "SRS import [2K524Y8G0J]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=2K524Y8G0J",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493390894000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "72716e85-e44c-48b3-9e9a-0bbdbfb1d09a",
          "citation": "USP",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "99121e11-6942-4a34-a15c-a3dc401eaa3a",
          "citation": "BLOOD CELLS, RED [USP]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "7f9a033a-ab8f-4428-b61e-826ecbbe7bcf",
          "citation": "RED BLOOD CELLS [MART.]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "faa2a5ab-2f3b-4ae1-865b-7265b2ad87f2",
          "citation": "RED BLOOD CELLS [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "39ebe617-9ac2-41aa-817d-e5419674021d",
          "citation": "HUMAN RED BLOOD CELLS [WHO-DD]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "888d875c-516c-6a49-504c-0203ff0431eb",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "880cad81-05ee-16c3-2bce-85639208f5de",
          "citation": "WHO-DD",
          "doc_type": "WHO DRUG DICTIONARY",
          "public_domain": true
        },
        {
          "uuid": "a4fbec0c-b5d7-470d-8b2e-544a299520f6",
          "citation": "NHANES",
          "url": "https://wwwn.cdc.gov/nchs/nhanes/search/variablelist.aspx?Component=Laboratory&Cycle=2017-2018",
          "doc_type": "CENTER FOR DISEASE CONTROL",
          "public_domain": true
        },
        {
          "uuid": "fd8ec82f-5a32-4bde-bd9f-885adefe6155",
          "citation": "Beaumont, K., et al. \"Pharmacokinetics and metabolism of a sulphamide NK2 antagonist in rat, dog and human.\" Xenobiotica 30.6 (2000): 627-642.",
          "url": "https://www.tandfonline.com/doi/pdf/10.1080/004982500406453",
          "doc_type": "JA",
          "public_domain": true
        },
        {
          "uuid": "051cd781-dea4-8a5c-31a2-bf589659e62e",
          "citation": "SMS",
          "doc_type": "EMA LIST",
          "public_domain": true
        }
      ],
      "definition_type": "PRIMARY",
      "definition_level": "COMPLETE",
      "uuid": "22853a32-0a2e-4df0-8c37-72ef23381f1f",
      "version": "14",
      "structurally_diverse": {
        "uuid": "2bc982e2-f22a-4acf-9199-dccbd10e3c2c",
        "fraction_material_type": "cell",
        "fraction_name": "erythrocyte",
        "parent_substance": {
          "uuid": "880f791a-c271-4ca1-b95e-ccb11c9f5a61",
          "refuuid": "973bd8f6-2f9b-4f89-8143-9125fe597dc5",
          "name": "HOMO SAPIENS WHOLE",
          "unii": "G0T704E6Z3",
          "linking_id": "G0T704E6Z3",
          "ref_pname": "HOMO SAPIENS WHOLE",
          "substance_class": "reference"
        },
        "part": [
          "blood"
        ],
        "references": [
          "72716e85-e44c-48b3-9e9a-0bbdbfb1d09a",
          "aff83fb4-120a-4d0c-a447-0fed38ea523f"
        ],
        "source_material_class": "ORGANISM",
        "source_material_type": "HUMAN"
      },
      "modifications": {
        "uuid": "5f7a00ab-caf8-4062-9777-5435034e250b"
      },
      "unii": "2K524Y8G0J"
    }
  ]
}