{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2025-09-19",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "codes": [
        {
          "uuid": "497c26cb-e94d-41fc-80cc-ae38a9715819",
          "code": "200-936-1",
          "type": "PRIMARY",
          "url": "https://echa.europa.eu/substance-information/-/substanceinfo/100.000.852",
          "code_system": "ECHA (EC/EINECS)",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "d559c3af-5340-4388-aeed-9e68767536ce",
          "code": "6428",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/compound/6428",
          "code_system": "PUBCHEM",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "6f7629d6-1dcc-4458-bc5d-01ff1ee177f5",
          "code": "76-13-1",
          "type": "PRIMARY",
          "url": "https://commonchemistry.cas.org/detail?cas_rn=76-13-1",
          "code_system": "CAS",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93",
            "6e5f72d5-0c6f-4657-b8e9-f34e4b353b18"
          ]
        },
        {
          "uuid": "c8bf2623-332a-4c77-969c-0ba62f3c9201",
          "code": "C96191",
          "type": "PRIMARY",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96191",
          "code_system": "NCI_THESAURUS",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "161ede26-e5e8-4bd9-9099-d36e0c130bda",
          "code": "C007786",
          "type": "PRIMARY",
          "url": "http://www.ncbi.nlm.nih.gov/mesh/67007786",
          "code_system": "MESH",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "8a5da04c-5ddd-4a71-9f02-4932dd42b3bb",
          "code": "21 CFR 173.342",
          "comments": "PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION|Subpart D--Specific Usage Additives|Sec. 173.342 Chlorofluorocarbon 113 and perfluorohexane.",
          "type": "PRIMARY",
          "url": "http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=173.342",
          "code_system": "CFR",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "8b9360aa-695f-4de9-ba85-b8682ac96c62",
          "code": "38585",
          "comments": "RxNorm",
          "type": "PRIMARY",
          "url": "https://rxnav.nlm.nih.gov/REST/rxcui/38585/allProperties.xml?prop=all",
          "code_system": "RXCUI",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "5a3b4337-58af-45b7-a54d-88a66777738f",
          "code": "21 CFR 189.191",
          "comments": "PART 189 -- SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD|Subpart C--Substances Generally Prohibited From Direct Addition or Use as Human Food|Sec. 189.191 Chlorofluorocarbon propellants.",
          "type": "PRIMARY",
          "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=189.191",
          "code_system": "CFR",
          "references": [
            "e111da35-f8fb-4832-a0ec-365c6713ae93"
          ]
        },
        {
          "uuid": "0a3123a4-ae9d-5d64-973b-ed893ec9615c",
          "code": "145",
          "type": "PRIMARY",
          "url": "https://pubchem.ncbi.nlm.nih.gov/source/hsdb/145",
          "code_system": "HSDB",
          "references": [
            "e02b95bc-184b-3239-4e5a-e85248edec1f"
          ]
        },
        {
          "uuid": "98ba334f-e9ee-d846-d01a-6fce96c0bd53",
          "code": "1,1,2-Trichloro-1,2,2-trifluoroethane",
          "type": "PRIMARY",
          "url": "https://en.wikipedia.org/wiki/1,1,2-Trichloro-1,2,2-trifluoroethane",
          "code_system": "WIKIPEDIA",
          "references": [
            "e683c3d9-55ca-a9b7-784e-3f45e36b0393"
          ]
        },
        {
          "uuid": "191c7731-296b-dc4f-48fb-c6933edc0733",
          "code": "DTXSID6021377",
          "type": "PRIMARY",
          "url": "https://comptox.epa.gov/dashboard/chemical/details/DTXSID6021377",
          "code_system": "EPA CompTox",
          "references": [
            "8de892ce-427b-181a-aa87-a35aa2660ec2"
          ]
        },
        {
          "uuid": "e5a31c20-fd8e-6b57-f81c-6b847fb2a742",
          "code": "C45678",
          "comments": "Industrial Aid",
          "type": "CONCEPT",
          "url": "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C45678",
          "code_system": "NCI_THESAURUS",
          "references": [
            "3dd39994-77d5-9032-5b4e-7074877e04d3"
          ]
        },
        {
          "uuid": "af53c54d-0f5a-4379-8898-faf4bc66c82f",
          "code": "0739N04X3A",
          "type": "PRIMARY",
          "code_system": "FDA UNII"
        },
        {
          "uuid": "dd0c994b-f9d4-543a-6bdc-da1e6b3355df",
          "code": "100000079956",
          "type": "PRIMARY",
          "code_system": "SMS_ID",
          "references": [
            "90d73a56-cfd8-c023-3bc9-71707d8486ef"
          ]
        }
      ],
      "relationships": [
        {
          "uuid": "bbbd60a5-0c03-4746-8bc9-2f2318e34939",
          "amount": {
            "uuid": "02e4ebfb-a4a7-4220-82c9-d60f70a660f7"
          },
          "type": "ACTIVE MOIETY",
          "related_substance": {
            "uuid": "76c7ddcb-d682-4a18-9ea0-e7b0ff43bc09",
            "refuuid": "80d774e0-f230-4330-8c59-a9353e9a2fa5",
            "name": "1,1,2-TRICHLOROTRIFLUOROETHANE",
            "unii": "0739N04X3A",
            "linking_id": "0739N04X3A",
            "ref_pname": "1,1,2-TRICHLOROTRIFLUOROETHANE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "de34e96e-69ce-4fa4-8bfa-86c15dc2ec0d",
          "amount": {
            "uuid": "7c96958a-3555-499a-9590-b4899d90186a"
          },
          "type": "PARENT->IMPURITY",
          "references": [
            "923ae466-1a36-8677-5f25-fc0b8672abf1"
          ],
          "related_substance": {
            "uuid": "06c88814-0dbf-4601-bf18-3ff32e014694",
            "refuuid": "17e8fd8e-ba04-4c79-9a6a-ccba5698793f",
            "name": "HALOTHANE",
            "unii": "UQT9G45D1P",
            "linking_id": "UQT9G45D1P",
            "ref_pname": "HALOTHANE",
            "substance_class": "reference"
          }
        },
        {
          "uuid": "ea9949bd-3782-4182-85d9-3149fd6a531f",
          "amount": {
            "uuid": "280e8dad-5fbc-47f3-b85b-053169b8dd68",
            "units": "PPM",
            "high_limit": 10
          },
          "qualification": "USP",
          "type": "PARENT->IMPURITY",
          "interaction_type": "CHROMATOGRAPHIC PURITY (GC)",
          "references": [
            "e52ef7e6-0324-9cda-152e-16101e33bdf3"
          ],
          "related_substance": {
            "uuid": "6c966954-b5bb-49a7-92ca-090cc03fc2aa",
            "refuuid": "4c9ff4e3-9ee5-4bdb-ae7d-ac8b9109310b",
            "name": "DESFLURANE",
            "unii": "CRS35BZ94Q",
            "linking_id": "CRS35BZ94Q",
            "ref_pname": "DESFLURANE",
            "substance_class": "reference"
          }
        }
      ],
      "substance_class": "chemical",
      "names": [
        {
          "uuid": "299a4570-34bb-47a9-be0f-a2a4091d0853",
          "name": "1,1,2-TRICHLOR-1,2,2-TRIFLUORETHANE",
          "stdName": "1,1,2-TRICHLOR-1,2,2-TRIFLUORETHANE",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5f76e76a-8c22-4d4d-9b75-98d7c574677d"
          ],
          "display_name": false
        },
        {
          "uuid": "b6015baa-df04-4071-8b02-271b4f925f77",
          "name": "1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE",
          "stdName": "1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "60205614-5709-4303-9b24-dc8bbd272997",
            "a07ba98e-958b-40ae-b3b3-692d160141d5",
            "dea72370-cbad-42a0-b0a2-011acc692926",
            "10737c8c-b39e-4075-a2cc-8d87f6040c08"
          ],
          "display_name": false
        },
        {
          "uuid": "80dac241-137c-4109-a552-07cdc7bc9399",
          "name": "1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE [HSDB]",
          "stdName": "1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE [HSDB]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a07ba98e-958b-40ae-b3b3-692d160141d5",
            "10737c8c-b39e-4075-a2cc-8d87f6040c08"
          ],
          "display_name": false
        },
        {
          "uuid": "9946e420-a54e-4843-a93b-239b75fe73ca",
          "name": "1,1,2-TRICHLOROTRIFLUOROETHANE",
          "stdName": "1,1,2-TRICHLOROTRIFLUOROETHANE",
          "type": "sys",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a07ba98e-958b-40ae-b3b3-692d160141d5",
            "dea72370-cbad-42a0-b0a2-011acc692926"
          ],
          "display_name": true
        },
        {
          "uuid": "0f52c461-09a6-4832-b1a9-c8198e206012",
          "name": "DESFLURANE IMPURITY G [EP IMPURITY]",
          "stdName": "DESFLURANE IMPURITY G [EP IMPURITY]",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "5ca96e4a-302d-4c66-933d-1feff989ddbb"
          ],
          "display_name": false
        },
        {
          "uuid": "4ecab4a1-8ed2-4f3f-bf1d-239e19e03d80",
          "name": "FLUOROCARBON 113",
          "stdName": "FLUOROCARBON 113",
          "type": "cn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "a07ba98e-958b-40ae-b3b3-692d160141d5",
            "dea72370-cbad-42a0-b0a2-011acc692926"
          ],
          "display_name": false
        },
        {
          "uuid": "7b6a4d3e-2400-421f-95e4-950fa33b1872",
          "name": "FREON 113",
          "stdName": "FREON 113",
          "type": "bn",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3456f013-a04f-4081-b31d-7e2fc957ee6f"
          ],
          "display_name": false
        },
        {
          "uuid": "f1f4d8f4-1836-487a-8ef7-e33082ae6226",
          "name": "R 113",
          "stdName": "R 113",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "3456f013-a04f-4081-b31d-7e2fc957ee6f"
          ],
          "display_name": false
        },
        {
          "uuid": "fc0dff88-8ec9-4e73-bba4-e5e572e2a440",
          "name": "R-113",
          "stdName": "R-113",
          "type": "cd",
          "languages": [
            "en"
          ],
          "preferred": false,
          "references": [
            "0ee975ea-2267-45db-bb10-0d758921b23b"
          ],
          "display_name": false
        }
      ],
      "references": [
        {
          "uuid": "5f76e76a-8c22-4d4d-9b75-98d7c574677d",
          "citation": "CHEMID",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE",
            "AUTO_SELECTED"
          ]
        },
        {
          "uuid": "3456f013-a04f-4081-b31d-7e2fc957ee6f",
          "citation": "KNOVEL SOLVENTS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "0ee975ea-2267-45db-bb10-0d758921b23b",
          "citation": "FDA_SRS",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "dea72370-cbad-42a0-b0a2-011acc692926",
          "citation": "JECFA",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "a07ba98e-958b-40ae-b3b3-692d160141d5",
          "citation": "JECFA: JOINT FAO/WHO COMMITTEE FOOD ADD",
          "doc_type": "JECFA: JOINT FAO/WHO COMMITTEE FOOD ADD",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "10737c8c-b39e-4075-a2cc-8d87f6040c08",
          "citation": "HSDB",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "e111da35-f8fb-4832-a0ec-365c6713ae93",
          "citation": "SRS CODE IMPORT",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389664000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "fa38726c-bb59-4b6c-a66c-671f82b83d85",
          "citation": "SRS import [0739N04X3A]",
          "url": "http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=0739N04X3A",
          "doc_type": "SRS",
          "public_domain": true,
          "document_date": 1493389664000,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "7360a170-7afe-4856-a09d-60b42ea03c97",
          "citation": "HAWLEYS CHEMICAL DICTIONARY",
          "doc_type": "SRS",
          "public_domain": true,
          "tags": [
            "NOMEN"
          ]
        },
        {
          "uuid": "60205614-5709-4303-9b24-dc8bbd272997",
          "citation": "1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE [HSDB]",
          "doc_type": "SRS_LOCATOR",
          "public_domain": true
        },
        {
          "uuid": "e683c3d9-55ca-a9b7-784e-3f45e36b0393",
          "citation": "WIKI",
          "url": "https://en.wikipedia.org/wiki/1,1,2-Trichloro-1,2,2-trifluoroethane",
          "doc_type": "WIKI",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "e02b95bc-184b-3239-4e5a-e85248edec1f",
          "citation": "WEBSITE",
          "url": "https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+76-13-1",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "8de892ce-427b-181a-aa87-a35aa2660ec2",
          "citation": "WEBSITE",
          "url": "https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=76-13-1",
          "doc_type": "WEBSITE",
          "public_domain": true,
          "tags": [
            "NOMEN",
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "90d73a56-cfd8-c023-3bc9-71707d8486ef",
          "citation": "EU-SRS",
          "doc_type": "EMA LIST",
          "public_domain": true
        },
        {
          "uuid": "923ae466-1a36-8677-5f25-fc0b8672abf1",
          "citation": "EP",
          "doc_type": "EP",
          "public_domain": true
        },
        {
          "uuid": "3dd39994-77d5-9032-5b4e-7074877e04d3",
          "doc_type": "SYSTEM",
          "public_domain": true
        },
        {
          "uuid": "e52ef7e6-0324-9cda-152e-16101e33bdf3",
          "citation": "USP43-NF38 - 1253, Desflurane Monograph",
          "doc_type": "USPNF",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        },
        {
          "uuid": "6e5f72d5-0c6f-4657-b8e9-f34e4b353b18",
          "citation": "STN",
          "doc_type": "STN (SCIFINDER)",
          "public_domain": true
        },
        {
          "uuid": "5ca96e4a-302d-4c66-933d-1feff989ddbb",
          "citation": "11.2",
          "doc_type": "EP",
          "public_domain": true,
          "tags": [
            "PUBLIC_DOMAIN_RELEASE"
          ]
        }
      ],
      "definition_type": "PRIMARY",
      "moieties": [
        {
          "uuid": "26f1612b-6334-4fc4-a1b9-4fd9c9535c37",
          "id": "26f1612b-6334-4fc4-a1b9-4fd9c9535c37",
          "molfile": "\n  Marvin  01132102092D          \n\n  8  7  0  0  0  0            999 V2000\n    2.5370   -0.7234    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6599   -0.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.8383   -0.0372    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    1.9250   -1.4147    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n    0.8349   -0.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.6541   -1.4816    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -0.7234    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n    0.5971    0.0000    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  3  2  1  0  0  0  0\n  4  2  1  0  0  0  0\n  2  5  1  0  0  0  0\n  6  5  1  0  0  0  0\n  7  5  1  0  0  0  0\n  8  5  1  0  0  0  0\nM  END",
          "smiles": "C(C(Cl)(F)F)(Cl)(Cl)F",
          "formula": "C2Cl3F3",
          "atropisomerism": "No",
          "charge": 0,
          "count": 1,
          "stereochemistry": "ACHIRAL",
          "count_amount": {
            "type": "MOL RATIO",
            "average": 1,
            "units": "MOL RATIO",
            "uuid": "7e319fac-d51c-478a-bcc2-91c0e4e2d78f"
          },
          "defined_stereo": 0,
          "ez_centers": 0,
          "molecular_weight": "187.3755",
          "optical_activity": "NONE",
          "stereo_centers": 0
        }
      ],
      "definition_level": "COMPLETE",
      "uuid": "80d774e0-f230-4330-8c59-a9353e9a2fa5",
      "version": "12",
      "structure": {
        "id": "ec1489e7-8420-45d8-87f0-89984b925d8f",
        "molfile": "\n  Marvin  01132112132D          \n\n  8  7  0  0  0  0            999 V2000\n    0.8349   -0.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    1.6599   -0.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    0.0000   -0.7234    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n    0.6541   -1.4816    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    0.5971    0.0000    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n    1.9250   -1.4147    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0\n    2.5370   -0.7234    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    1.8383   -0.0372    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  3  1  1  0  0  0  0\n  4  1  1  0  0  0  0\n  5  1  1  0  0  0  0\n  6  2  1  0  0  0  0\n  7  2  1  0  0  0  0\n  8  2  1  0  0  0  0\nM  END",
        "smiles": "C(C(Cl)(F)F)(Cl)(Cl)F",
        "formula": "C2Cl3F3",
        "atropisomerism": "No",
        "charge": 0,
        "count": 1,
        "stereochemistry": "ACHIRAL",
        "defined_stereo": 0,
        "ez_centers": 0,
        "molecular_weight": "187.3755",
        "optical_activity": "NONE",
        "references": [
          "7360a170-7afe-4856-a09d-60b42ea03c97",
          "fa38726c-bb59-4b6c-a66c-671f82b83d85"
        ],
        "stereo_centers": 0
      },
      "unii": "0739N04X3A"
    }
  ]
}