{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-23",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 20
    }
  },
  "results": [
    {
      "update_type": "Revised",
      "initial_posting_date": "02/20/2018",
      "package_ndc": "0409-9043-01",
      "generic_name": "Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection",
      "contact_info": "844-646-4398",
      "availability": "Unavailable",
      "related_info": "Next Delivery and Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay",
      "openfda": {
        "application_number": [
          "ANDA071167"
        ],
        "brand_name": [
          "BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE"
        ],
        "generic_name": [
          "BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE"
        ],
        "manufacturer_name": [
          "Hospira, Inc."
        ],
        "product_ndc": [
          "0409-9043",
          "0409-1159",
          "0409-1160",
          "0409-1162",
          "0409-1163",
          "0409-1165",
          "0409-9046",
          "0409-9045",
          "0409-9042"
        ],
        "product_type": [
          "HUMAN PRESCRIPTION DRUG"
        ],
        "route": [
          "INFILTRATION",
          "PERINEURAL"
        ],
        "substance_name": [
          "BUPIVACAINE HYDROCHLORIDE",
          "EPINEPHRINE BITARTRATE"
        ],
        "rxcui": [
          "1012377",
          "1012384",
          "1012396",
          "1012404",
          "1672917",
          "1672919",
          "1724786",
          "1724787",
          "1724880",
          "1724884",
          "1725078",
          "1725082",
          "1867594",
          "1867596"
        ],
        "spl_id": [
          "6e442bfd-d3da-4913-8585-ce3485644364"
        ],
        "spl_set_id": [
          "02a845c3-4521-4926-e397-25ab536e7cf6"
        ],
        "package_ndc": [
          "0409-1159-18",
          "0409-1159-01",
          "0409-1159-19",
          "0409-1159-02",
          "0409-1160-18",
          "0409-1160-01",
          "0409-1162-18",
          "0409-1162-01",
          "0409-1162-19",
          "0409-1162-02",
          "0409-1163-18",
          "0409-1163-01",
          "0409-1165-18",
          "0409-1165-01",
          "0409-1165-19",
          "0409-1165-02",
          "0409-9043-11",
          "0409-9043-01",
          "0409-9046-11",
          "0409-9046-01",
          "0409-9045-11",
          "0409-9045-01",
          "0409-9045-16",
          "0409-9045-17",
          "0409-9042-11",
          "0409-9042-01",
          "0409-9042-16",
          "0409-9042-17"
        ],
        "unii": [
          "7TQO7W3VT8",
          "30Q7KI53AK"
        ]
      },
      "update_date": "10/21/2026",
      "therapeutic_category": [
        "Anesthesia"
      ],
      "dosage_form": "Injection",
      "presentation": "Bupivacaine Hydrochloride and Epinephrine, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-9043-01)",
      "company_name": "Hospira, Inc., a Pfizer Company",
      "shortage_reason": "Other",
      "status": "Current"
    }
  ]
}