{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-21",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "discontinued_date": "05/21/2026",
      "update_type": "New",
      "initial_posting_date": "05/21/2026",
      "package_ndc": "50242-085-27",
      "generic_name": "Alteplase Injection",
      "contact_info": "800-551-2231",
      "related_info": "Discontinuation of the 100mg vial configuration",
      "openfda": {
        "application_number": [
          "BLA103172"
        ],
        "brand_name": [
          "ACTIVASE"
        ],
        "generic_name": [
          "ALTEPLASE"
        ],
        "manufacturer_name": [
          "Genentech, Inc."
        ],
        "product_ndc": [
          "50242-085",
          "50242-044"
        ],
        "product_type": [
          "HUMAN PRESCRIPTION DRUG"
        ],
        "rxcui": [
          "1804799",
          "1804802",
          "1804804",
          "1804806"
        ],
        "spl_id": [
          "48ed2eb6-728a-41d8-b024-6b34e75dc4dc"
        ],
        "spl_set_id": [
          "c669f77c-fa48-478b-a14b-80b20a0139c2"
        ],
        "package_ndc": [
          "50242-044-13",
          "50242-085-27"
        ]
      },
      "update_date": "05/21/2026",
      "therapeutic_category": [
        "Cardiovascular",
        "Hematology",
        "Neurology"
      ],
      "dosage_form": "Injection",
      "presentation": "Activase, Injection, 1 KIT in 1 CARTON (50242-085-27) * 100 mL in 1 VIAL, SINGLE-USE * 100 mL in 1 VIAL, SINGLE USE (NDC 50242-085-27)",
      "company_name": "Genentech, Inc",
      "status": "To Be Discontinued"
    }
  ]
}