{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-09-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "0573-0164",
      "generic_name": "diphenhydramine citrate and ibuprofen",
      "labeler_name": "Haleon US Holdings LLC",
      "brand_name": "ADVIL PM",
      "active_ingredients": [
        {
          "name": "DIPHENHYDRAMINE CITRATE",
          "strength": "38 mg/1"
        },
        {
          "name": "IBUPROFEN",
          "strength": "200 mg/1"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "0573-0164-04",
          "description": "4 TABLET, COATED in 1 POUCH (0573-0164-04)",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-05",
          "description": "2 BOTTLE in 1 CARTON (0573-0164-05)  / 2 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-08",
          "description": "1 VIAL in 1 PACKAGE (0573-0164-08)  / 8 TABLET, COATED in 1 VIAL",
          "marketing_start_date": "20170317",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-09",
          "description": "8 TABLET, COATED in 1 VIAL (0573-0164-09)",
          "marketing_start_date": "20170317",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-12",
          "description": "6 POUCH in 1 CARTON (0573-0164-12)  / 2 TABLET, COATED in 1 POUCH",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-14",
          "description": "2 POUCH in 1 CARTON (0573-0164-14)  / 2 TABLET, COATED in 1 POUCH",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-20",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-20)  / 20 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-21",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-21)  / 30 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-30",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-30)  / 40 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-32",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-32)  / 50 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-33",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-33)  / 50 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-40",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-40)  / 80 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-41",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-41)  / 100 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-43",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-43)  / 120 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-44",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-44)  / 140 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-45",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-45)  / 180 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-46",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-46)  / 180 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-49",
          "description": "1 BOTTLE in 1 CARTON (0573-0164-49)  / 200 TABLET, COATED in 1 BOTTLE",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-55",
          "description": "50 POUCH in 1 TRAY (0573-0164-55)  / 2 TABLET, COATED in 1 POUCH",
          "marketing_start_date": "20051221",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-65",
          "description": "120 TABLET, COATED in 1 BOTTLE (0573-0164-65)",
          "marketing_start_date": "20160930",
          "sample": false
        },
        {
          "package_ndc": "0573-0164-91",
          "description": "3000 POUCH in 1 BOX (0573-0164-91)  / 2 TABLET, COATED in 1 POUCH",
          "marketing_start_date": "20051221",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
        "manufacturer_name": [
          "Haleon US Holdings LLC"
        ],
        "rxcui": [
          "895664"
        ],
        "spl_set_id": [
          "658fc201-47c9-6a6d-8af9-6208298d43b4"
        ],
        "is_original_packager": [
          true
        ],
        "nui": [
          "N0000000160",
          "M0001335",
          "N0000175722"
        ],
        "pharm_class_moa": [
          "Cyclooxygenase Inhibitors [MoA]"
        ],
        "pharm_class_cs": [
          "Anti-Inflammatory Agents, Non-Steroidal [CS]"
        ],
        "pharm_class_epc": [
          "Nonsteroidal Anti-inflammatory Drug [EPC]"
        ],
        "unii": [
          "4OD433S209",
          "WK2XYI10QM"
        ]
      },
      "marketing_category": "NDA",
      "dosage_form": "TABLET, COATED",
      "spl_id": "15971707-84cd-4742-e063-6394a90af906",
      "product_type": "HUMAN OTC DRUG",
      "route": [
        "ORAL"
      ],
      "marketing_start_date": "20051221",
      "product_id": "0573-0164_15971707-84cd-4742-e063-6394a90af906",
      "application_number": "NDA021394",
      "brand_name_base": "ADVIL PM",
      "pharm_class": [
        "Anti-Inflammatory Agents",
        "Non-Steroidal [CS]",
        "Cyclooxygenase Inhibitors [MoA]",
        "Histamine H1 Receptor Antagonists [MoA]",
        "Histamine-1 Receptor Antagonist [EPC]",
        "Nonsteroidal Anti-inflammatory Drug [EPC]"
      ]
    }
  ]
}