{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-09",
    "results": {
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  "results": [
    {
      "product_ndc": "0280-0083",
      "generic_name": "Anhydrous citric acid, Sodium bicarbonate (heat-treated)",
      "labeler_name": "Bayer Healthcare LLC",
      "brand_name": "Alka-Seltzer Heartburn Relief Lemon Lime",
      "active_ingredients": [
        {
          "name": "SODIUM BICARBONATE",
          "strength": "1650 mg/1"
        },
        {
          "name": "CITRIC ACID MONOHYDRATE",
          "strength": "1000 mg/1"
        }
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      "packaging": [
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          "description": "18 PACKET in 1 CARTON (0280-0083-01)  / 2 TABLET, EFFERVESCENT in 1 PACKET",
          "marketing_start_date": "20220216",
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        },
        {
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          "description": "12 PACKET in 1 CARTON (0280-0083-02)  / 2 TABLET, EFFERVESCENT in 1 PACKET",
          "marketing_start_date": "20240401",
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        },
        {
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          "description": "36 PACKET in 1 CARTON (0280-0083-03)  / 2 TABLET, EFFERVESCENT in 1 PACKET",
          "marketing_start_date": "20240401",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
        "manufacturer_name": [
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        "spl_set_id": [
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      },
      "marketing_category": "OTC MONOGRAPH DRUG",
      "dosage_form": "TABLET, EFFERVESCENT",
      "spl_id": "31b97b49-1db4-5da9-e063-6394a90a04c3",
      "product_type": "HUMAN OTC DRUG",
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      "product_id": "0280-0083_31b97b49-1db4-5da9-e063-6394a90a04c3",
      "application_number": "M001",
      "brand_name_base": "Alka-Seltzer Heartburn Relief Lemon Lime",
      "pharm_class": [
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        "Anti-coagulant [EPC]",
        "Calcium Chelating Activity [MoA]",
        "Calculi Dissolution Agent [EPC]",
        "Decreased Coagulation Factor Activity [PE]",
        "Increased Large Intestinal Motility [PE]",
        "Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]",
        "Osmotic Activity [MoA]",
        "Osmotic Laxative [EPC]"
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    }
  ]
}