{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-23",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "83027-0004",
      "marketing_end_date": "20280427",
      "generic_name": "Niacin, Nicotinamidum, Arnica Montana, Camphora, Nux Vomica, Veratrum Album, Adrenalinum, Aesculus Hippocastanum, Aurum Metallicum, Gelsemium Sempervirens, Heloderma (Horridus), Rhus Tox, Tabacum",
      "labeler_name": "Nutritional Specialties, Inc.",
      "brand_name": "Circulation",
      "active_ingredients": [
        {
          "name": "NIACIN",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "NIACINAMIDE",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "ARNICA MONTANA WHOLE",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "CAMPHOR (NATURAL)",
          "strength": "8 [hp_X]/mL"
        },
        {
          "name": "STRYCHNOS NUX-VOMICA SEED",
          "strength": "8 [hp_X]/mL"
        },
        {
          "name": "VERATRUM ALBUM ROOT",
          "strength": "8 [hp_X]/mL"
        },
        {
          "name": "EPINEPHRINE",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "HORSE CHESTNUT",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "GOLD",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "GELSEMIUM SEMPERVIRENS ROOT",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "HELODERMA HORRIDUM VENOM",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "TOXICODENDRON PUBESCENS LEAF",
          "strength": "12 [hp_X]/mL"
        },
        {
          "name": "TOBACCO LEAF",
          "strength": "12 [hp_X]/mL"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "83027-0004-1",
          "description": "60 mL in 1 BOTTLE, SPRAY (83027-0004-1)",
          "marketing_start_date": "20230413",
          "marketing_end_date": "20280427",
          "sample": false
        }
      ],
      "openfda": {
        "manufacturer_name": [
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        ],
        "spl_set_id": [
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        "is_original_packager": [
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          "M0016962",
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          "N0000175552",
          "N0000175555",
          "N0000175570",
          "M0003647",
          "N0000185508"
        ],
        "pharm_class_epc": [
          "Nicotinic Acid [EPC]",
          "Non-Standardized Plant Allergenic Extract [EPC]",
          "alpha-Adrenergic Agonist [EPC]",
          "beta-Adrenergic Agonist [EPC]",
          "Catecholamine [EPC]",
          "Standardized Chemical Allergen [EPC]"
        ],
        "pharm_class_cs": [
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          "Allergens [CS]",
          "Plant Proteins [CS]",
          "Seed Storage Proteins [CS]",
          "Catecholamines [CS]"
        ],
        "pharm_class_pe": [
          "Increased Histamine Release [PE]",
          "Cell-mediated Immunity [PE]",
          "Increased IgG Production [PE]"
        ],
        "pharm_class_moa": [
          "Adrenergic alpha-Agonists [MoA]",
          "Adrenergic beta-Agonists [MoA]"
        ],
        "unii": [
          "2679MF687A",
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          "O80TY208ZW",
          "N20HL7Q941",
          "269XH13919",
          "QNS6W5US1Z",
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          "79Y1949PYO",
          "639KR60Q1Q",
          "O9M1UQ4YIO",
          "6IO182RP7A",
          "6YR2608RSU"
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      },
      "marketing_category": "UNAPPROVED HOMEOPATHIC",
      "dosage_form": "SPRAY",
      "spl_id": "5e621e48-4dc4-4fbf-8d22-d5d095e30ac4",
      "product_type": "HUMAN OTC DRUG",
      "route": [
        "ORAL"
      ],
      "marketing_start_date": "20230413",
      "product_id": "83027-0004_5e621e48-4dc4-4fbf-8d22-d5d095e30ac4",
      "brand_name_base": "Circulation",
      "pharm_class": [
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        "Adrenergic beta-Agonists [MoA]",
        "Allergens [CS]",
        "Allergens [CS]",
        "Allergens [CS]",
        "Catecholamine [EPC]",
        "Catecholamines [CS]",
        "Cell-mediated Immunity [PE]",
        "Cell-mediated Immunity [PE]",
        "Cell-mediated Immunity [PE]",
        "Increased Histamine Release [PE]",
        "Increased Histamine Release [PE]",
        "Increased Histamine Release [PE]",
        "Increased IgG Production [PE]",
        "Increased IgG Production [PE]",
        "Nicotinic Acid [EPC]",
        "Nicotinic Acids [CS]",
        "Non-Standardized Plant Allergenic Extract [EPC]",
        "Non-Standardized Plant Allergenic Extract [EPC]",
        "Plant Proteins [CS]",
        "Plant Proteins [CS]",
        "Seed Storage Proteins [CS]",
        "Standardized Chemical Allergen [EPC]",
        "alpha-Adrenergic Agonist [EPC]",
        "beta-Adrenergic Agonist [EPC]"
      ]
    }
  ]
}