{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-07",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "66993-002",
      "generic_name": "estradiol",
      "labeler_name": "Prasco Laboratories",
      "brand_name": "Estradiol Vaginal Cream",
      "active_ingredients": [
        {
          "name": "ESTRADIOL",
          "strength": ".1 mg/g"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "66993-002-10",
          "description": "1 TUBE in 1 CARTON (66993-002-10)  / 42.5 g in 1 TUBE",
          "marketing_start_date": "20211001",
          "sample": false
        }
      ],
      "listing_expiration_date": "20271231",
      "openfda": {
        "manufacturer_name": [
          "Prasco Laboratories"
        ],
        "rxcui": [
          "310169"
        ],
        "spl_set_id": [
          "c895ac14-5dbd-4201-bf3e-ba7c38a4e994"
        ],
        "is_original_packager": [
          true
        ],
        "nui": [
          "M0447348",
          "N0000175825",
          "N0000000100"
        ],
        "pharm_class_cs": [
          "Estradiol Congeners [CS]"
        ],
        "pharm_class_epc": [
          "Estrogen [EPC]"
        ],
        "pharm_class_moa": [
          "Estrogen Receptor Agonists [MoA]"
        ],
        "unii": [
          "4TI98Z838E"
        ]
      },
      "marketing_category": "ANDA",
      "dosage_form": "CREAM",
      "spl_id": "11e56187-77a7-4d0d-9929-bc4527bac7c0",
      "product_type": "HUMAN PRESCRIPTION DRUG",
      "route": [
        "VAGINAL"
      ],
      "marketing_start_date": "20211001",
      "product_id": "66993-002_11e56187-77a7-4d0d-9929-bc4527bac7c0",
      "application_number": "ANDA212313",
      "brand_name_base": "Estradiol Vaginal Cream",
      "pharm_class": [
        "Estradiol Congeners [CS]",
        "Estrogen Receptor Agonists [MoA]",
        "Estrogen [EPC]"
      ]
    }
  ]
}