{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-09",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "52083-646",
      "generic_name": "Dextromethorphan HBr ,Guaifenesin ,Phenylephrine HCl",
      "labeler_name": "Kramer Novis",
      "brand_name": "DESGEN DM",
      "active_ingredients": [
        {
          "name": "DEXTROMETHORPHAN HYDROBROMIDE",
          "strength": "10 mg/5mL"
        },
        {
          "name": "GUAIFENESIN",
          "strength": "100 mg/5mL"
        },
        {
          "name": "PHENYLEPHRINE HYDROCHLORIDE",
          "strength": "5 mg/5mL"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "52083-646-16",
          "description": "474 mL in 1 BOTTLE (52083-646-16)",
          "marketing_start_date": "20141018",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
        "manufacturer_name": [
          "Kramer Novis"
        ],
        "rxcui": [
          "1044949"
        ],
        "spl_set_id": [
          "6ab47174-e1fd-47ce-8788-06b7cdad5218"
        ],
        "is_original_packager": [
          true
        ],
        "upc": [
          "0352083646164"
        ],
        "nui": [
          "N0000193956",
          "N0000008867",
          "N0000009560"
        ],
        "pharm_class_epc": [
          "Expectorant [EPC]"
        ],
        "pharm_class_pe": [
          "Decreased Respiratory Secretion Viscosity [PE]",
          "Increased Respiratory Secretions [PE]"
        ],
        "unii": [
          "9D2RTI9KYH",
          "495W7451VQ",
          "04JA59TNSJ"
        ]
      },
      "marketing_category": "OTC MONOGRAPH DRUG",
      "dosage_form": "SOLUTION",
      "spl_id": "affd083a-31b7-4862-ac14-e4ccc4d2ca7e",
      "product_type": "HUMAN OTC DRUG",
      "route": [
        "ORAL"
      ],
      "marketing_start_date": "20141018",
      "product_id": "52083-646_affd083a-31b7-4862-ac14-e4ccc4d2ca7e",
      "application_number": "M012",
      "brand_name_base": "DESGEN DM",
      "pharm_class": [
        "Adrenergic alpha1-Agonists [MoA]",
        "Decreased Respiratory Secretion Viscosity [PE]",
        "Expectorant [EPC]",
        "Increased Respiratory Secretions [PE]",
        "Sigma-1 Agonist [EPC]",
        "Sigma-1 Receptor Agonists [MoA]",
        "Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]",
        "Uncompetitive NMDA Receptor Antagonists [MoA]",
        "alpha-1 Adrenergic Agonist [EPC]"
      ]
    }
  ]
}