{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-13",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "43853-0017",
      "generic_name": "Agnus Castus, Angelica Sinensis, Apis Mellifica, Arnica Montana, Cimicifuga Racemosa, Estradiol, Estriol, Folliculinum, Galium Aparine, Glycyrrhiza Glabra, Korean Ginseng, Oophorinum (Suis), Progesterone, Sepia, Thuja Occidentalis, Viscum Album",
      "labeler_name": "ProBLEN",
      "brand_name": "Estrogen and Progesterone",
      "active_ingredients": [
        {
          "name": "CHASTE TREE",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "ANGELICA SINENSIS ROOT",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "APIS MELLIFERA",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "ARNICA MONTANA",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "BLACK COHOSH",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "ESTRADIOL",
          "strength": "9 [hp_C]/mL"
        },
        {
          "name": "ESTRIOL",
          "strength": "9 [hp_C]/mL"
        },
        {
          "name": "ESTRONE",
          "strength": "9 [hp_C]/mL"
        },
        {
          "name": "GALIUM APARINE",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "GLYCYRRHIZA GLABRA",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "ASIAN GINSENG",
          "strength": "3 [hp_X]/mL"
        },
        {
          "name": "SUS SCROFA OVARY",
          "strength": "30 [hp_C]/mL"
        },
        {
          "name": "PROGESTERONE",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "SEPIA OFFICINALIS JUICE",
          "strength": "30 [hp_C]/mL"
        },
        {
          "name": "THUJA OCCIDENTALIS LEAFY TWIG",
          "strength": "6 [hp_X]/mL"
        },
        {
          "name": "VISCUM ALBUM FRUITING TOP",
          "strength": "3 [hp_X]/mL"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "43853-0017-2",
          "description": "1 BOTTLE, SPRAY in 1 CARTON (43853-0017-2)  / 30 mL in 1 BOTTLE, SPRAY (43853-0017-1)",
          "marketing_start_date": "20170112",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
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        "spl_set_id": [
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        ],
        "is_original_packager": [
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        "nui": [
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          "N0000184306",
          "N0000185001",
          "M0000728",
          "M0002274",
          "M0447348",
          "N0000175825",
          "N0000000100",
          "N0000185371",
          "N0000185375",
          "M0006342",
          "M0016962",
          "M0017672",
          "N0000175601"
        ],
        "pharm_class_epc": [
          "Standardized Insect Venom Allergenic Extract [EPC]",
          "Estrogen [EPC]",
          "Non-Standardized Food Allergenic Extract [EPC]",
          "Non-Standardized Plant Allergenic Extract [EPC]",
          "Progesterone [EPC]"
        ],
        "pharm_class_pe": [
          "Increased Histamine Release [PE]",
          "Cell-mediated Immunity [PE]",
          "Increased IgG Production [PE]"
        ],
        "pharm_class_cs": [
          "Allergens [CS]",
          "Bee Venoms [CS]",
          "Estradiol Congeners [CS]",
          "Dietary Proteins [CS]",
          "Plant Proteins [CS]",
          "Progesterone [CS]"
        ],
        "pharm_class_moa": [
          "Estrogen Receptor Agonists [MoA]"
        ],
        "unii": [
          "433OSF3U8A",
          "B66F4574UG",
          "7S82P3R43Z",
          "O80TY208ZW",
          "K73E24S6X9",
          "4TI98Z838E",
          "FB33469R8E",
          "2DI9HA706A",
          "Z4B6561488",
          "2788Z9758H",
          "CUQ3A77YXI",
          "S7YTV04R8O",
          "4G7DS2Q64Y",
          "QDL83WN8C2",
          "1NT28V9397",
          "BK9092J5MP"
        ]
      },
      "marketing_category": "UNAPPROVED HOMEOPATHIC",
      "dosage_form": "SPRAY",
      "spl_id": "31103d8c-5ee4-483e-bd45-aac9eda84b68",
      "product_type": "HUMAN OTC DRUG",
      "route": [
        "ORAL"
      ],
      "marketing_start_date": "20170112",
      "product_id": "43853-0017_31103d8c-5ee4-483e-bd45-aac9eda84b68",
      "brand_name_base": "Estrogen and Progesterone",
      "pharm_class": [
        "Allergens [CS]",
        "Allergens [CS]",
        "Bee Venoms [CS]",
        "Cell-mediated Immunity [PE]",
        "Cell-mediated Immunity [PE]",
        "Dietary Proteins [CS]",
        "Estradiol Congeners [CS]",
        "Estrogen Receptor Agonists [MoA]",
        "Estrogen [EPC]",
        "Increased Histamine Release [PE]",
        "Increased Histamine Release [PE]",
        "Increased IgG Production [PE]",
        "Non-Standardized Food Allergenic Extract [EPC]",
        "Non-Standardized Plant Allergenic Extract [EPC]",
        "Plant Proteins [CS]",
        "Progesterone [CS]",
        "Progesterone [EPC]",
        "Standardized Insect Venom Allergenic Extract [EPC]"
      ]
    }
  ]
}