{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-22",
    "results": {
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  "results": [
    {
      "product_ndc": "37000-523",
      "generic_name": "Acetaminophen, Phenylephrine Hydrochloride, Doxylamine Succinate, and Dextromethorphan Hydrobromide",
      "labeler_name": "The Procter & Gamble Manufacturing Company",
      "brand_name": "NyQuil Severe plus Vicks VapoCool Cold and Flu",
      "brand_name_suffix": "Cold and Flu",
      "active_ingredients": [
        {
          "name": "DEXTROMETHORPHAN HYDROBROMIDE",
          "strength": "10 mg/1"
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        {
          "name": "ACETAMINOPHEN",
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        },
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        {
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      "packaging": [
        {
          "package_ndc": "37000-523-02",
          "description": "2 TABLET, COATED in 1 POUCH (37000-523-02)",
          "marketing_start_date": "20180801",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
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        "rxcui": [
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        "spl_set_id": [
          "724d0889-5ba5-3125-e053-2a91aa0a92c1"
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        "is_original_packager": [
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          "9D2RTI9KYH",
          "362O9ITL9D",
          "04JA59TNSJ",
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      "dosage_form": "TABLET, COATED",
      "spl_id": "401e3485-6a7e-3dc8-e063-6294a90a859c",
      "product_type": "HUMAN OTC DRUG",
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      "marketing_start_date": "20180801",
      "product_id": "37000-523_401e3485-6a7e-3dc8-e063-6294a90a859c",
      "application_number": "M012",
      "brand_name_base": "NyQuil Severe plus Vicks VapoCool",
      "pharm_class": [
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        "Antihistamine [EPC]",
        "Histamine Receptor Antagonists [MoA]",
        "Sigma-1 Agonist [EPC]",
        "Sigma-1 Receptor Agonists [MoA]",
        "Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]",
        "Uncompetitive NMDA Receptor Antagonists [MoA]",
        "alpha-1 Adrenergic Agonist [EPC]"
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}