{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-02",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "product_ndc": "21130-183",
      "generic_name": "loperamide hydrochloride, simethicone",
      "labeler_name": "Safeway",
      "brand_name": "signature care anti diarrheal anti gas",
      "active_ingredients": [
        {
          "name": "LOPERAMIDE HYDROCHLORIDE",
          "strength": "2 mg/1"
        },
        {
          "name": "DIMETHICONE",
          "strength": "125 mg/1"
        }
      ],
      "finished": true,
      "packaging": [
        {
          "package_ndc": "21130-183-62",
          "description": "24 BLISTER PACK in 1 CARTON (21130-183-62)  / 1 TABLET in 1 BLISTER PACK",
          "marketing_start_date": "20190625",
          "sample": false
        },
        {
          "package_ndc": "21130-183-89",
          "description": "18 BLISTER PACK in 1 CARTON (21130-183-89)  / 1 TABLET in 1 BLISTER PACK",
          "marketing_start_date": "20181010",
          "sample": false
        }
      ],
      "listing_expiration_date": "20261231",
      "openfda": {
        "manufacturer_name": [
          "Safeway"
        ],
        "rxcui": [
          "978001"
        ],
        "spl_set_id": [
          "53829e72-d22c-434d-a108-1972081a6efb"
        ],
        "is_original_packager": [
          true
        ],
        "nui": [
          "N0000010282"
        ],
        "pharm_class_pe": [
          "Skin Barrier Activity [PE]"
        ],
        "unii": [
          "77TI35393C",
          "92RU3N3Y1O"
        ]
      },
      "marketing_category": "ANDA",
      "dosage_form": "TABLET",
      "spl_id": "22865692-fb31-425b-ac78-2d3cd7998c04",
      "product_type": "HUMAN OTC DRUG",
      "route": [
        "ORAL"
      ],
      "marketing_start_date": "20181010",
      "product_id": "21130-183_22865692-fb31-425b-ac78-2d3cd7998c04",
      "application_number": "ANDA209837",
      "brand_name_base": "signature care anti diarrheal anti gas",
      "pharm_class": [
        "Opioid Agonist [EPC]",
        "Opioid Agonists [MoA]",
        "Skin Barrier Activity [PE]"
      ]
    }
  ]
}