{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-02",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Pro-Health Sensitivity Relief Sodium Fluoride and Potassium Nitrate POTASSIUM NITRATE NITRATE ION SODIUM FLUORIDE FLUORIDE ION CELLULOSE GUM CETYLPYRIDINIUM CHLORIDE TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS WATER HYDRATED SILICA GLYCERIN SORBITOL SODIUM LAURYL SULFATE ALCOHOL XANTHAN GUM SACCHARIN SODIUM POLYSORBATE 80"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by Procter & Gamble, Cincinnati, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredients Purpose Potassium nitrate 5% Toothpaste for sensitive teeth Sodium fluoride 0.243% (0.14% w/v fluoride ion) Toothpaste for cavity prevention"
      ],
      "active_ingredient_table": [
        "<table width=\"70%\"><col width=\"50%\" align=\"left\" valign=\"top\"/><col width=\"50%\" align=\"right\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>Potassium nitrate 5%</td><td>Toothpaste for sensitive teeth</td></tr><tr><td>Sodium fluoride 0.243% (0.14% w/v fluoride ion)</td><td>Toothpaste for cavity prevention</td></tr></tbody></table>"
      ],
      "purpose": [
        "Active ingredients Purpose Potassium nitrate 5% Toothpaste for sensitive teeth Sodium fluoride 0.243% (0.14% w/v fluoride ion) Toothpaste for cavity prevention"
      ],
      "purpose_table": [
        "<table width=\"70%\"><col width=\"50%\" align=\"left\" valign=\"top\"/><col width=\"50%\" align=\"right\" valign=\"top\"/><thead><tr><th><content styleCode=\"italics\">Active ingredients</content></th><th><content styleCode=\"italics\">Purpose</content></th></tr></thead><tbody><tr><td>Potassium nitrate 5%</td><td>Toothpaste for sensitive teeth</td></tr><tr><td>Sodium fluoride 0.243% (0.14% w/v fluoride ion)</td><td>Toothpaste for cavity prevention</td></tr></tbody></table>"
      ],
      "indications_and_usage": [
        "Uses when used regularly, builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets or contact aids in the prevention of cavities"
      ],
      "warnings": [
        "Warnings When using this product do not use longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if problem lasts or gets worse. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "when_using": [
        "When using this product do not use longer than four weeks unless recommended by a dentist."
      ],
      "stop_use": [
        "Stop use and ask a dentist if problem lasts or gets worse. Sensitive teeth may indicate a serious problem that may need prompt care."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions 12 yrs. & older: Apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist. Make sure to brush all sensitive areas of the teeth. do not swallow do not use in children under 12 yrs."
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, hydrated silica, glycerin, sorbitol, sodium lauryl sulfate, trisodium phosphate, flavor, cellulose gum, alcohol (0.7%), sodium saccharin, xanthan gum, polysorbate 80, cetylpyridinium chloride, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "recent_major_changes": [
        ""
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 170 g Tube Carton Crest 3DWHITE TOOTHPASTE FOR SENSITIVE TEETH AND CAVITY PREVENTION SENSITIVITY RELIEF Whitens teeth with 24/7 Sensitivity Protection* BRILLIANT MINT 3-3.7 OZ (104 g) TUBES EACH; TOTAL NET WT 11.1 OZ (314 g) label"
      ],
      "set_id": "59dff762-7f66-8bdc-e063-6294a90a9f18",
      "id": "59dff774-f9cd-e640-e063-6394a90a09c3",
      "effective_time": "20260825",
      "version": "1",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Pro-Health Sensitivity Relief"
        ],
        "generic_name": [
          "SODIUM FLUORIDE AND POTASSIUM NITRATE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "84126-671"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "POTASSIUM NITRATE",
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "1038800"
        ],
        "spl_id": [
          "59dff774-f9cd-e640-e063-6394a90a09c3"
        ],
        "spl_set_id": [
          "59dff762-7f66-8bdc-e063-6294a90a9f18"
        ],
        "package_ndc": [
          "84126-671-33"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "RU45X2JN0Z",
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}