{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-02",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "ISNTREE HYALURONIC ACID WATERY SUNSCREEN AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE OCTISALATE OCTISALATE OCTOCRYLENE OCTOCRYLENE HOMOSALATE HOMOSALATE AVOBENZONE AVOBENZONE TRIPROPYLENE GLYCOL CETEARYL OLIVATE CETYL ALCOHOL DIMETHICONE VINYL DIMETHICONE/METHICONE SILSESQUIOXANE CROSSPOLYMER XYLITYLGLUCOSIDE XYLITOL SORBITAN OLIVATE PANTHENOL SILICA ETHYLHEXYL METHOXYCRYLENE XANTHAN GUM WATER HYDROXYACETOPHENONE GLYCERIN CARBOMER DIETHYLHEXYL 2,6-NAPHTHALATE DIPHENYLSILOXY PHENYL TRIMETHICONE POLYMETHYLSILSESQUIOXANE (4.5 MICRONS) PENTYLENE GLYCOL TROMETHAMINE TOCOPHEROL NIACINAMIDE XYLOSE PROPANEDIOL BUTYLENE GLYCOL TRIMETHYL PENTAPHENYL TRISILOXANE 1,2-HEXANEDIOL ANHYDROXYLITOL SODIUM STEAROYL GLUTAMATE"
      ],
      "active_ingredient": [
        "Active ingredients Avobenzone 2.85 % Homosalate 7.00 % Octisalate 4.50 % Octocrylene 9.00 %"
      ],
      "purpose": [
        "Purpose sunscreen"
      ],
      "indications_and_usage": [
        "Uses • helps prevent sunburn • higher SPF gives more sunburn protection • if used as directed with other sun protection measures (see Directions) decreases the risk of skin cancer and early skin aging caused by the sun"
      ],
      "warnings": [
        "Warnings For external use only."
      ],
      "do_not_use": [
        "Do not use • on damaged skin or broken skin."
      ],
      "when_using": [
        "When using this product • keep out of eyes. Rinse with water to remove."
      ],
      "stop_use": [
        "Stop use and ask a doctor if •rash or irritation develops and lasts."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions ■ apply liberally 15 minutes before sun exposure. Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: • limit time in the sun, especially from 10 a.m. - 2 p.m. • wear long-sleeved shirts, pants, hats, and sunglasses ■ children under 6 months of age: Ask a doctor ■ reapply at least every 2 hours. ■ use a water-resistant sunscreen if swimming or sweating."
      ],
      "other_safety_information": [
        "Other information ■ protect the product from exessive heat and direct sun ■ Sun alert: Limiting sun exposure, wearing protective clothing, and using sunscreens may reduce the risks of skin aging, skin cancer, and other harmful effects of the sun."
      ],
      "inactive_ingredient": [
        "Inactive ingredients Water, Propanediol, Dimethicone, Silica, Ethylhexyl Methoxycrylene, Diethylhexyl 2,6-Naphthalate, Niacinamide, Butylene Glycol, Tripropylene Glycol, Xylitylglucoside, Xylitol, Xylose, Hydrolyzed Hyaluronic Acid, Diphenylsiloxy Phenyl Trimethicone, Lauryl Dimethicone, Polymethylsilsesquioxane, Trimethyl Pentaphenyl Trisiloxane, Pentylene Glycol, Poly C10-30 Alkyl Acrylate, 1,2-Hexanediol, Cetearyl Olivate, Hydroxyacetophenone, Sorbitan Olivate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Tromethamine, Glyceryl Glucoside, Anhydroxylitol, Sodium Stearoyl Glutamate, Hydroxypropyltrimonium Hyaluronate, Glycerin, Panthenol, Tocopherol, Cetyl Alcohol, Carbomer, Xanthan Gum"
      ],
      "package_label_principal_display_panel": [
        "ISNTREE HYALURONIC ACID WATERY SUNSCREEN"
      ],
      "set_id": "59ac747a-f9c7-2c18-e063-6394a90a2306",
      "id": "59ac747a-f9c9-2c18-e063-6394a90a2306",
      "effective_time": "20260823",
      "version": "1",
      "openfda": {
        "application_number": [
          "M020"
        ],
        "brand_name": [
          "ISNTREE HYALURONIC ACID WATERY SUNSCREEN"
        ],
        "generic_name": [
          "AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE"
        ],
        "manufacturer_name": [
          "ISNTREE Inc."
        ],
        "product_ndc": [
          "81100-507"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "TOPICAL"
        ],
        "substance_name": [
          "OCTISALATE",
          "OCTOCRYLENE",
          "HOMOSALATE",
          "AVOBENZONE"
        ],
        "spl_id": [
          "59ac747a-f9c9-2c18-e063-6394a90a2306"
        ],
        "spl_set_id": [
          "59ac747a-f9c7-2c18-e063-6394a90a2306"
        ],
        "package_ndc": [
          "81100-507-01",
          "81100-507-02"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "4X49Y0596W",
          "5A68WGF6WM",
          "V06SV4M95S",
          "G63QQF2NOX"
        ]
      }
    }
  ]
}