{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
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  "results": [
    {
      "spl_product_data_elements": [
        "Crest 3D White Advanced Glamorous White Sodium Fluoride MICA TITANIUM DIOXIDE SODIUM SACCHARIN CELLULOSE GUM CARBOMER SUCRALOSE DISODIUM PYROPHOSPHATE SORBITOL HYDRATED SILICA SODIUM LAURYL SULFATE SODIUM HYDROXIDE POLYSORBATE 80 WATER SODIUM FLUORIDE FLUORIDE ION"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.16% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, cellulose gum, sodium saccharin, carbomer, sucralose, polysorbate 80, titanium dioxide, mica"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 93 g Tube Carton CREST 3D WHITE ADVANCED GLAMOROUS WHITE DAILY WHITENING UPKEEP WHITER TEETH IN 5 DAYS NET WT 3.3 OZ (92 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE Artwork"
      ],
      "set_id": "f5b18988-68c7-40f9-e053-2995a90a22bc",
      "id": "47e5cb38-b55d-9cfb-e063-6394a90a8fda",
      "effective_time": "20260108",
      "version": "12",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest 3D White Advanced Glamorous White"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "69423-768"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "47e5cb38-b55d-9cfb-e063-6394a90a8fda"
        ],
        "spl_set_id": [
          "f5b18988-68c7-40f9-e053-2995a90a22bc"
        ],
        "package_ndc": [
          "69423-768-38",
          "69423-768-77",
          "69423-768-39",
          "69423-768-93",
          "69423-768-23",
          "69423-768-66",
          "69423-768-03"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}