{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest 3D White Advanced Charcoal Sodium Fluoride SODIUM HYDROXIDE POLYSORBATE 80 SODIUM ACID PYROPHOSPHATE SORBITOL CARBOXYMETHYLCELLULOSE SODIUM HYDRATED SILICA WATER SODIUM LAURYL SULFATE SACCHARIN SODIUM MICA TITANIUM DIOXIDE CARBOXYPOLYMETHYLENE SODIUM FLUORIDE FLUORIDE ION ACTIVATED CHARCOAL"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warning Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, sodium hydroxide, flavor, cellulose gum, sodium saccharin, carbomer, charcoal powder, polysorbate 80, mica, titanium dioxide"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 107 g Tube Carton Crest 3D WHITE NET WT 3.8 OZ (107 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE WHIENENING ADVANCED CHARCOAL REMOVES 90% MORE SUFACE STAINS* STARTS WHITENING AFTER 1 BRUSH LABEL"
      ],
      "set_id": "f4eb8111-53da-17ae-e053-2a95a90a1127",
      "id": "4ee0534f-21b4-92f4-e063-6394a90a98a8",
      "effective_time": "20260407",
      "version": "12",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest 3D White Advanced Charcoal"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "69423-767"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "4ee0534f-21b4-92f4-e063-6394a90a98a8"
        ],
        "spl_set_id": [
          "f4eb8111-53da-17ae-e053-2a95a90a1127"
        ],
        "package_ndc": [
          "69423-767-28",
          "69423-767-38",
          "69423-767-76",
          "69423-767-27",
          "69423-767-29",
          "69423-767-39",
          "69423-767-24",
          "69423-767-33",
          "69423-767-03",
          "69423-767-66",
          "69423-767-93"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}