{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "effective_time": "20100825",
      "inactive_ingredient": [
        "Inactive ingredients: Sorbitol, Water, HYDRATED SILICA, SODIUM HEXAMETAPHOSPHATE, Glycerin, SODIUM LAURYL SULPHATE, flavor, ZINC LACTATE, PEG-6, CELLULOSE GUM, SODIUM PHOSPHATE, SODIUM GLUCONATE, Sodium Saccharin, Titanium Dioxide, BLUE 1, YELLOW 4."
      ],
      "purpose": [
        "ANTICAVITY, ANTIGINGIVITIS, ANTISENSITIVITY TOOTHPASTE"
      ],
      "keep_out_of_reach_of_children": [
        "KEEP OUT OF REACH OF CHILDREN"
      ],
      "warnings": [
        "WARNINGS WARNINGS: WHEN USING THIS PRODUCT DO NOT USE FOR SENSITIVITY LONGER THAN FOUR WEEKS UNLESS RECOMMENDED BY A DENTIST. STOP USE AND ASK A DENTIST IF THE SENSITIVITY PROBLEM PERSISTS OR WORSENS. SENSITIVE TEETH MAY INDICATE A SERIOUS PROBLEM THAT MAY NEED PROMPT CARE. If you accidentally swallow more than used for brushing, seek professional help or contact a Poison Control Center immediately."
      ],
      "spl_product_data_elements": [
        "Up and Up Anticavity Toothpaste Multi Function Stannous Fluoride STANNOUS FLUORIDE FLUORIDE ION SORBITOL WATER SILICON DIOXIDE SODIUM POLYMETAPHOSPHATE GLYCERIN SODIUM LAURYL SULFATE ZINC LACTATE POLYETHYLENE GLYCOL 300 CROSCARMELLOSE SODIUM SODIUM PHOSPHATE SODIUM GLUCONATE SACCHARIN SODIUM TITANIUM DIOXIDE FD&C BLUE NO. 1 clean mint flavor"
      ],
      "openfda": {},
      "version": "1",
      "dosage_and_administration": [
        "Directions Adults and children 12 years and older Brush teeth thoroughly, PREFERABLY AFTER EACH MEAL,or at least twice a day, or as directed by your dentist. DO NOT SWALLOW Children under 12 ASK A dentist or PHYSICIAN Other information PRODUCTS CONTAINING STANNOUS FLUORIDE MAY PRODUCE SURFACE STAINING OF THE TEETH. ADEQUATE TOOTHBRUSHING MAY PREVENT THESE STAIN WHICH ARE NOT HARMFUL OR PERMANENT."
      ],
      "package_label_principal_display_panel": [
        "Principal Display Panel image of container"
      ],
      "indications_and_usage": [
        "USES HELPS AID IN THE PREVENTION OF CAVITIES HELPS PREVENT GINGIVITIS HELPS CONTROL PLAQUE BACTERIA THAT CONTRIBUTE TO THE DEVELOPMENT OF GINGIVITIS BUILD INCREASING PROTECTION AGAINST PAINFUL SENSITIVITY OF THE TEETH TO COLD, HEAT, ACIDS, SWEETS OR CONTACT."
      ],
      "set_id": "eef7c016-0b43-41cc-8dc5-2e95393f2544",
      "id": "b0b132a3-c7b9-4996-b326-36b7fe1c0167",
      "active_ingredient": [
        "Active Ingredients STANNOUS FLUORIDE 0.454%...................... ANTICAVITY, ANTIGINGIVITIS, (0.16% W/V FLUORIDE ION) ANTISENSITIVITY TOOTHPASTE"
      ]
    }
  ]
}