{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-30",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Complete plus Whitening Sodium Fluoride CITRIC ACID MONOHYDRATE SODIUM BENZOATE POTASSIUM SORBATE MICA SACCHARIN SODIUM SODIUM ACID PYROPHOSPHATE SODIUM LAURYL SULFATE CARBOXYPOLYMETHYLENE SORBITOL FD&C BLUE NO. 1 WATER HYDRATED SILICA TITANIUM DIOXIDE CARBOXYMETHYLCELLULOSE SODIUM SODIUM FLUORIDE FLUORIDE ION SODIUM HYDROXIDE POLYSORBATE 80"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, carbomer, polysorbate 80, citric acid, sodium benzoate, potassium sorbate, mica, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 153 g Carton Crest ® plus complete NET WT/PESO NETO 5.4 OZ (153 g) FLUORIDE TOOTHPASTE / PASTA DENTAL CON FLUORURO EXTRA WHITENING with tartar protection A WHITER SMILE IN ONE TUBE* clean mint menta refrescante Crest Complete plus Extra Whitening"
      ],
      "set_id": "e3b1f139-4fe8-f005-e053-2995a90a53b4",
      "id": "47e4b6a0-2e39-3e5f-e063-6394a90afe71",
      "effective_time": "20260108",
      "version": "5",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Complete plus Whitening"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "69423-894"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "2585483"
        ],
        "spl_id": [
          "47e4b6a0-2e39-3e5f-e063-6394a90afe71"
        ],
        "spl_set_id": [
          "e3b1f139-4fe8-f005-e053-2995a90a53b4"
        ],
        "package_ndc": [
          "69423-894-54"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}