{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
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  "results": [
    {
      "spl_product_data_elements": [
        "Crest Braces Care Cavity Protection Stannous Fluoride SUCRALOSE HYDRATED SILICA SORBITOL SODIUM CITRATE ZINC CITRATE WATER SODIUM LAURYL SULFATE SODIUM GLUCONATE CARRAGEENAN SACCHARIN SODIUM XANTHAN GUM TITANIUM DIOXIDE SODIUM HYDROXIDE FD&C BLUE NO. 1 STANNOUS FLUORIDE FLUORIDE ION STANNOUS CHLORIDE"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Stannous fluoride 0.454% (0.14% w/v fluoride ion)"
      ],
      "purpose": [
        "Purposes Anticavity, antigingivitis toothpaste"
      ],
      "indications_and_usage": [
        "Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age . If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age . If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 6 yrs. of age & older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow supervise children's brushing until good habits are established children under 6 yrs.: ask a dentist"
      ],
      "storage_and_handling": [
        "Other information products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist this product is specially formulated to help prevent staining see your dentist regularly"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium gluconate, carrageenan, flavor, sodium citrate, xanthan gum, zinc citrate, sodium hydroxide, stannous chloride, sodium saccharin, sucralose, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-844-436-7026"
      ],
      "package_label_principal_display_panel": [
        "Crest Braces Care Cavity Protection Toothpaste 99 g carton Crest BRACES CARE FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS toothpaste ANTI-BACTERIAL DEFENSE* *fights plaque bacteria associated with gingivitis FOR PEOPLE WHO WEAR BRACES AGES 6+ FRESH MINT NET WT 4.1 OZ (116 g) Crest Braces Care Cavity Protection Toothpaste"
      ],
      "set_id": "d823cba4-c4cf-7d7a-e053-2995a90a01f0",
      "id": "47e497ef-68fc-4404-e063-6394a90a0dac",
      "effective_time": "20260108",
      "version": "7",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Braces Care Cavity Protection"
        ],
        "generic_name": [
          "STANNOUS FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "69423-879"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "STANNOUS FLUORIDE"
        ],
        "rxcui": [
          "416784"
        ],
        "spl_id": [
          "47e497ef-68fc-4404-e063-6394a90a0dac"
        ],
        "spl_set_id": [
          "d823cba4-c4cf-7d7a-e053-2995a90a01f0"
        ],
        "package_ndc": [
          "69423-879-85",
          "69423-879-46",
          "69423-879-63",
          "69423-879-41"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "3FTR44B32Q"
        ]
      }
    }
  ]
}