{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-29",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest Premium Plus Scope Dual Blast Active Foam Sodium Fluoride WATER SORBITOL HYDRATED SILICA SODIUM LAURYL SULFATE ALCOHOL CARBOXYMETHYLCELLULOSE SODIUM GLYCERIN POLYSORBATE 80 SODIUM BENZOATE CARBOXYPOLYMETHYLENE CETYLPYRIDINIUM CHLORIDE BENZOIC ACID TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM ACID PYROPHOSPHATE SODIUM HYDROXIDE XANTHAN GUM SODIUM FLUORIDE FLUORIDE ION SACCHARIN SODIUM"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Dist. by Procter & Gamble,Cincinnati, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients sorbitol, water, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, alcohol (0.7%), xanthan gum, sodium saccharin, glycerin, cellulose gum, carbomer, polysorbate 80, sodium benzoate, cetylpyridinium chloride, benzoic acid, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 204 g Tube Carton Crest plus PREMIUM NET WT/PESO NETO 7.2OZ (204 g) ANTICAVITY FLUORIDE TOOTHPASTE PASTA DENTAL ANTICARIES CON FLUORURO ACTIVE FOAM +WHITENING scope ® DUALBLAST® BLASTS AWAY 99.9% OF BAD BREATH GERMS* intense mint menta intensa 990"
      ],
      "set_id": "b788d16a-8a58-0352-e053-2a95a90a965e",
      "id": "47e3398c-efdd-b995-e063-6394a90a2a9b",
      "effective_time": "20260108",
      "version": "13",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest Premium Plus Scope Dual Blast Active Foam"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "37000-990"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "47e3398c-efdd-b995-e063-6394a90a2a9b"
        ],
        "spl_set_id": [
          "b788d16a-8a58-0352-e053-2a95a90a965e"
        ],
        "package_ndc": [
          "37000-990-72",
          "37000-990-52",
          "37000-990-03",
          "37000-990-35",
          "37000-990-23"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}