{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest 3D White Brilliance Charcoal Sodium Fluoride COCAMIDOPROPYL BETAINE SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS POVIDONE, UNSPECIFIED POLYETHYLENE GLYCOL 300 ACTIVATED CHARCOAL WATER SACCHARIN SODIUM HYDRATED SILICA SODIUM LAURYL SULFATE SUCRALOSE TITANIUM DIOXIDE MICA SODIUM FLUORIDE FLUORIDE ION SODIUM HEXAMETAPHOSPHATE CARRAGEENAN GLYCERIN XANTHAN GUM"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.15% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, disodium pyrophosphate, sodium lauryl sulfate, flavor, sodium hydroxide, cellulose gum, sodium saccharin, carbomer, charcoal powder, sucralose, polysorbate 80, mica, titanium dioxide"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 130 g Carton LARGE SIZE CREST 3D WHITE NEW WT 4.6 OZ (130 g) FLUORIDE ANTICAVITY TOOTHPASTE ENAMEL SAFE BRILLIANCE CHARCOAL MINT EXTRA STRENGTH WHITENING WHITER TEETH IN 3 DAYS Artwork"
      ],
      "set_id": "b7882679-339c-554f-e053-2995a90afa7f",
      "id": "47e32c0d-afe7-af72-e063-6394a90af9cf",
      "effective_time": "20260108",
      "version": "10",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest 3D White Brilliance Charcoal"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "Procter & Gamble Manfuacturing Company"
        ],
        "product_ndc": [
          "37000-989"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "47e32c0d-afe7-af72-e063-6394a90af9cf"
        ],
        "spl_set_id": [
          "b7882679-339c-554f-e053-2995a90afa7f"
        ],
        "package_ndc": [
          "37000-989-39",
          "37000-989-35",
          "37000-989-46"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}