{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-28",
    "results": {
      "skip": 0,
      "limit": 1,
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    }
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  "results": [
    {
      "spl_product_data_elements": [
        "Native Whitening Sodium Fluoride TITANIUM DIOXIDE CARRAGEENAN XANTHAN GUM WATER HYDRATED SILICA GLYCERIN STEVIA REBAUDIANA WHOLE SODIUM COCOYL GLUTAMATE COCAMIDOPROPYL BETAINE XYLITOL PEPPERMINT OIL SODIUM FLUORIDE FLUORIDE ION"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "Distr. by Native San Francisco, CA 94111"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.14% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children’s brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients glycerin, water, hydrated silica, xylitol, flavor, mentha piperita (peppermint) oil, sodium cocoyl glutamate, xanthan gum, carrageenan, cocamidopropyl betaine, stevia rebaudiana extract, titanium dioxide"
      ],
      "questions": [
        "Questions? 1-888-964-1211"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 116 g tube in carton WITH FLUORIDE WHITENS TEETH FRESHENS BREATH FIGHTS CAVITIES NATIVE FLUORIDE ANTICAVITY TOOTHPASTE WHITENING WILD MINT & PEPPERMINT OIL NET WT 4.1 OZ (116 g) 973"
      ],
      "set_id": "a5248d35-f488-3457-e053-2995a90a411e",
      "id": "47e32c0d-afe6-af72-e063-6394a90af9cf",
      "effective_time": "20260108",
      "version": "7",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Native Whitening"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "37000-973"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "47e32c0d-afe6-af72-e063-6394a90af9cf"
        ],
        "spl_set_id": [
          "a5248d35-f488-3457-e053-2995a90a411e"
        ],
        "package_ndc": [
          "37000-973-41"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}