{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-10-26",
    "results": {
      "skip": 0,
      "limit": 1,
      "total": 1
    }
  },
  "results": [
    {
      "spl_product_data_elements": [
        "Crest complete plus Whitening Deep Clean Sodium Fluoride SORBITOL WATER HYDRATED SILICA POLYSORBATE 80 SODIUM LAURYL SULFATE ZINC CITRATE CARBOXYMETHYLCELLULOSE SODIUM CARRAGEENAN SACCHARIN SODIUM SODIUM CITRATE TITANIUM DIOXIDE FD&C BLUE NO. 1 SODIUM FLUORIDE FLUORIDE ION with Blue stripe"
      ],
      "spl_unclassified_section": [
        "Drug Facts",
        "DISTR. BY PROCTER & GAMBLE, CINCINNATI, OH 45202"
      ],
      "active_ingredient": [
        "Active ingredient Sodium fluoride 0.243% (0.14% w/v fluoride ion)"
      ],
      "purpose": [
        "Purpose Anticavity toothpaste"
      ],
      "indications_and_usage": [
        "Use helps protect against cavities"
      ],
      "warnings": [
        "Warnings Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "keep_out_of_reach_of_children": [
        "Keep out of reach of children under 6 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."
      ],
      "dosage_and_administration": [
        "Directions adults and children 2 yrs. & older: brush teeth thoroughly after meals or at least twice a day or use as directed by a dentist do not swallow to minimize swallowing use a pea-sized amount in children under 6 supervise children's brushing until good habits are established children under 2 yrs.: ask a dentist"
      ],
      "inactive_ingredient": [
        "Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, flavor, cellulose gum, zinc citrate, carrageenan, sodium saccharin, sodium citrate, polysorbate 80, titanium dioxide, blue 1"
      ],
      "questions": [
        "Questions? 1-800-492-7378"
      ],
      "package_label_principal_display_panel": [
        "PRINCIPAL DISPLAY PANEL - 153 g Tube Carton Crest ® plus complete NET WT 5.4 OZ (153 g) FLUORIDE TOOTHPASTE + WHITENING DEEP CLEAN UP TO 2X DEEPER CLEAN FEELING* effervescent mint 946"
      ],
      "set_id": "973ce138-c64e-c059-e053-2a95a90a3148",
      "id": "47e3006c-545e-f700-e063-6294a90ad6c2",
      "effective_time": "20260108",
      "version": "6",
      "openfda": {
        "application_number": [
          "M021"
        ],
        "brand_name": [
          "Crest complete plus Whitening Deep Clean"
        ],
        "generic_name": [
          "SODIUM FLUORIDE"
        ],
        "manufacturer_name": [
          "The Procter & Gamble Manufacturing Company"
        ],
        "product_ndc": [
          "37000-946"
        ],
        "product_type": [
          "HUMAN OTC DRUG"
        ],
        "route": [
          "DENTAL"
        ],
        "substance_name": [
          "SODIUM FLUORIDE"
        ],
        "rxcui": [
          "891775"
        ],
        "spl_id": [
          "47e3006c-545e-f700-e063-6294a90ad6c2"
        ],
        "spl_set_id": [
          "973ce138-c64e-c059-e053-2a95a90a3148"
        ],
        "package_ndc": [
          "37000-946-02",
          "37000-946-54"
        ],
        "is_original_packager": [
          true
        ],
        "unii": [
          "8ZYQ1474W7"
        ]
      }
    }
  ]
}